Circadian rhythm of adrenergic regulation of adrenocorticotropin and cortisol secretion in man.
Publication
, Journal Article
Naylor, MR; Krishnan, KR; Manepalli, AN; Ritchie, JC; Wilson, WH; Carroll, BJ
Published in: J Clin Endocrinol Metab
August 1988
The effects of the alpha-adrenergic agonist methoxamine on the human hypothalamic-pituitary-adrenal axis was assessed by a placebo-controlled study in the morning and one in the evening. A 5-mg iv bolus dose of methoxamine in normal subjects caused a significant rise in plasma ACTH and cortisol concentrations in the morning study. However, no significant change in plasma cortisol or ACTH concentrations was noted during the evening study. These studies suggest the existence of a diurnal variation in alpha 1-adrenergic regulation of the hypothalamic-pituitary-adrenal axis.
Duke Scholars
Published In
J Clin Endocrinol Metab
DOI
ISSN
0021-972X
Publication Date
August 1988
Volume
67
Issue
2
Start / End Page
404 / 406
Location
United States
Related Subject Headings
- Time Factors
- Receptors, Adrenergic, alpha
- Methoxamine
- Male
- Hydrocortisone
- Humans
- Endocrinology & Metabolism
- Circadian Rhythm
- Adult
- Adrenocorticotropic Hormone
Citation
APA
Chicago
ICMJE
MLA
NLM
Naylor, M. R., Krishnan, K. R., Manepalli, A. N., Ritchie, J. C., Wilson, W. H., & Carroll, B. J. (1988). Circadian rhythm of adrenergic regulation of adrenocorticotropin and cortisol secretion in man. J Clin Endocrinol Metab, 67(2), 404–406. https://doi.org/10.1210/jcem-67-2-404
Naylor, M. R., K. R. Krishnan, A. N. Manepalli, J. C. Ritchie, W. H. Wilson, and B. J. Carroll. “Circadian rhythm of adrenergic regulation of adrenocorticotropin and cortisol secretion in man.” J Clin Endocrinol Metab 67, no. 2 (August 1988): 404–6. https://doi.org/10.1210/jcem-67-2-404.
Naylor MR, Krishnan KR, Manepalli AN, Ritchie JC, Wilson WH, Carroll BJ. Circadian rhythm of adrenergic regulation of adrenocorticotropin and cortisol secretion in man. J Clin Endocrinol Metab. 1988 Aug;67(2):404–6.
Naylor, M. R., et al. “Circadian rhythm of adrenergic regulation of adrenocorticotropin and cortisol secretion in man.” J Clin Endocrinol Metab, vol. 67, no. 2, Aug. 1988, pp. 404–06. Pubmed, doi:10.1210/jcem-67-2-404.
Naylor MR, Krishnan KR, Manepalli AN, Ritchie JC, Wilson WH, Carroll BJ. Circadian rhythm of adrenergic regulation of adrenocorticotropin and cortisol secretion in man. J Clin Endocrinol Metab. 1988 Aug;67(2):404–406.
Published In
J Clin Endocrinol Metab
DOI
ISSN
0021-972X
Publication Date
August 1988
Volume
67
Issue
2
Start / End Page
404 / 406
Location
United States
Related Subject Headings
- Time Factors
- Receptors, Adrenergic, alpha
- Methoxamine
- Male
- Hydrocortisone
- Humans
- Endocrinology & Metabolism
- Circadian Rhythm
- Adult
- Adrenocorticotropic Hormone