An immunopathologic study of retinoblastoma protein.
Publication
, Journal Article
Sawaguchi, S; Peng, Y; Wong, F; Tso, MO
Published in: Trans Am Ophthalmol Soc
1990
We investigated the immunoreactivity of the retinoblastoma protein in eight retinoblastoma tumors of different stages of differentiation. All undifferentiated tumor cells failed to show immunoreactivity. In one patient, who had a family history of retinoblastoma and had been treated by radiation, the tumor had a large area of undifferentiated cells and small independent retinocytomas. The tumor cells in the retinocytoma and the cone cells in the adjacent retina, but not the undifferentiated tumor cells, showed positive staining with two anti-Rb antibodies. The immunoreactivity may be related to radiation or differentiation of retinoblastoma and cone cells.
Duke Scholars
Published In
Trans Am Ophthalmol Soc
ISSN
0065-9533
Publication Date
1990
Volume
88
Start / End Page
51 / 61
Location
United States
Related Subject Headings
- Retinoblastoma Protein
- Retinoblastoma
- Ophthalmology & Optometry
- Melanoma
- Male
- Infant
- Immunoenzyme Techniques
- Humans
- Female
- Eye Neoplasms
Citation
APA
Chicago
ICMJE
MLA
NLM
Sawaguchi, S., Peng, Y., Wong, F., & Tso, M. O. (1990). An immunopathologic study of retinoblastoma protein. Trans Am Ophthalmol Soc, 88, 51–61.
Sawaguchi, S., Y. Peng, F. Wong, and M. O. Tso. “An immunopathologic study of retinoblastoma protein.” Trans Am Ophthalmol Soc 88 (1990): 51–61.
Sawaguchi S, Peng Y, Wong F, Tso MO. An immunopathologic study of retinoblastoma protein. Trans Am Ophthalmol Soc. 1990;88:51–61.
Sawaguchi, S., et al. “An immunopathologic study of retinoblastoma protein.” Trans Am Ophthalmol Soc, vol. 88, 1990, pp. 51–61.
Sawaguchi S, Peng Y, Wong F, Tso MO. An immunopathologic study of retinoblastoma protein. Trans Am Ophthalmol Soc. 1990;88:51–61.
Published In
Trans Am Ophthalmol Soc
ISSN
0065-9533
Publication Date
1990
Volume
88
Start / End Page
51 / 61
Location
United States
Related Subject Headings
- Retinoblastoma Protein
- Retinoblastoma
- Ophthalmology & Optometry
- Melanoma
- Male
- Infant
- Immunoenzyme Techniques
- Humans
- Female
- Eye Neoplasms