Skip to main content

An immunopathologic study of retinoblastoma protein.

Publication ,  Journal Article
Sawaguchi, S; Peng, Y; Wong, F; Tso, MO
Published in: Trans Am Ophthalmol Soc
1990

We investigated the immunoreactivity of the retinoblastoma protein in eight retinoblastoma tumors of different stages of differentiation. All undifferentiated tumor cells failed to show immunoreactivity. In one patient, who had a family history of retinoblastoma and had been treated by radiation, the tumor had a large area of undifferentiated cells and small independent retinocytomas. The tumor cells in the retinocytoma and the cone cells in the adjacent retina, but not the undifferentiated tumor cells, showed positive staining with two anti-Rb antibodies. The immunoreactivity may be related to radiation or differentiation of retinoblastoma and cone cells.

Duke Scholars

Published In

Trans Am Ophthalmol Soc

ISSN

0065-9533

Publication Date

1990

Volume

88

Start / End Page

51 / 61

Location

United States

Related Subject Headings

  • Retinoblastoma Protein
  • Retinoblastoma
  • Ophthalmology & Optometry
  • Melanoma
  • Male
  • Infant
  • Immunoenzyme Techniques
  • Humans
  • Female
  • Eye Neoplasms
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sawaguchi, S., Peng, Y., Wong, F., & Tso, M. O. (1990). An immunopathologic study of retinoblastoma protein. Trans Am Ophthalmol Soc, 88, 51–61.
Sawaguchi, S., Y. Peng, F. Wong, and M. O. Tso. “An immunopathologic study of retinoblastoma protein.Trans Am Ophthalmol Soc 88 (1990): 51–61.
Sawaguchi S, Peng Y, Wong F, Tso MO. An immunopathologic study of retinoblastoma protein. Trans Am Ophthalmol Soc. 1990;88:51–61.
Sawaguchi, S., et al. “An immunopathologic study of retinoblastoma protein.Trans Am Ophthalmol Soc, vol. 88, 1990, pp. 51–61.
Sawaguchi S, Peng Y, Wong F, Tso MO. An immunopathologic study of retinoblastoma protein. Trans Am Ophthalmol Soc. 1990;88:51–61.

Published In

Trans Am Ophthalmol Soc

ISSN

0065-9533

Publication Date

1990

Volume

88

Start / End Page

51 / 61

Location

United States

Related Subject Headings

  • Retinoblastoma Protein
  • Retinoblastoma
  • Ophthalmology & Optometry
  • Melanoma
  • Male
  • Infant
  • Immunoenzyme Techniques
  • Humans
  • Female
  • Eye Neoplasms