The accuracy of statistical estimates in genetic studies of aging can be significantly improved.
Publication
, Journal Article
Yashin, AI; Arbeev, KG; Ukraintseva, SV
Published in: Biogerontology
June 2007
The sample size of the data used in genetic studies is often a factor limiting the accuracy of statistical estimates. In this paper we suggest a new approach to evaluation of genetic influence on risk of development of aging-related health disorders. The approach results in substantial improvement of the accuracy of statistical estimates without an increase in the size of the genetic sample. The approach is based on the joint analysis of data from the genetic samples and easily accessible non-genetic data, such as data collected in epidemiological, demographic, and longitudinal studies of human aging and aging-related pathologies.
Duke Scholars
Published In
Biogerontology
DOI
EISSN
1573-6768
ISSN
1389-5729
Publication Date
June 2007
Volume
8
Issue
3
Start / End Page
243 / 255
Related Subject Headings
- Sample Size
- Models, Statistical
- Longitudinal Studies
- Humans
- Gerontology
- Genotype
- Data Interpretation, Statistical
- Alleles
- Aging
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Yashin, A. I., Arbeev, K. G., & Ukraintseva, S. V. (2007). The accuracy of statistical estimates in genetic studies of aging can be significantly improved. Biogerontology, 8(3), 243–255. https://doi.org/10.1007/s10522-006-9072-4
Yashin, Anatoli I., Konstantin G. Arbeev, and Svetlana V. Ukraintseva. “The accuracy of statistical estimates in genetic studies of aging can be significantly improved.” Biogerontology 8, no. 3 (June 2007): 243–55. https://doi.org/10.1007/s10522-006-9072-4.
Yashin AI, Arbeev KG, Ukraintseva SV. The accuracy of statistical estimates in genetic studies of aging can be significantly improved. Biogerontology. 2007 Jun;8(3):243–55.
Yashin, Anatoli I., et al. “The accuracy of statistical estimates in genetic studies of aging can be significantly improved.” Biogerontology, vol. 8, no. 3, June 2007, pp. 243–55. Epmc, doi:10.1007/s10522-006-9072-4.
Yashin AI, Arbeev KG, Ukraintseva SV. The accuracy of statistical estimates in genetic studies of aging can be significantly improved. Biogerontology. 2007 Jun;8(3):243–255.
Published In
Biogerontology
DOI
EISSN
1573-6768
ISSN
1389-5729
Publication Date
June 2007
Volume
8
Issue
3
Start / End Page
243 / 255
Related Subject Headings
- Sample Size
- Models, Statistical
- Longitudinal Studies
- Humans
- Gerontology
- Genotype
- Data Interpretation, Statistical
- Alleles
- Aging
- 3202 Clinical sciences