Cancer in rodents: does it tell us about cancer in humans?
Publication
, Journal Article
Anisimov, VN; Ukraintseva, SV; Yashin, AI
Published in: Nature reviews. Cancer
October 2005
Information obtained from animal models (mostly mice and rats) has contributed substantially to the development of treatments for human cancers. However, important interspecies differences have to be taken into account when considering the mechanisms of cancer development and extrapolating the results from mice to humans. Comparative studies of cancer in humans and animal models mostly focus on genetic factors. This review discusses the bio-epidemiological aspects of cancer manifestation in humans and rodents that have been underrepresented in the literature.
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Published In
Nature reviews. Cancer
DOI
EISSN
1474-1768
ISSN
1474-175X
Publication Date
October 2005
Volume
5
Issue
10
Start / End Page
807 / 819
Related Subject Headings
- Species Specificity
- Sex Characteristics
- Rodent Diseases
- Rats
- Oncology & Carcinogenesis
- Neoplasms
- Neoplasm Regression, Spontaneous
- Mice
- Male
- Incidence
Citation
APA
Chicago
ICMJE
MLA
NLM
Anisimov, V. N., Ukraintseva, S. V., & Yashin, A. I. (2005). Cancer in rodents: does it tell us about cancer in humans? Nature Reviews. Cancer, 5(10), 807–819. https://doi.org/10.1038/nrc1715
Anisimov, Vladimir N., Svetlana V. Ukraintseva, and Anatoly I. Yashin. “Cancer in rodents: does it tell us about cancer in humans?” Nature Reviews. Cancer 5, no. 10 (October 2005): 807–19. https://doi.org/10.1038/nrc1715.
Anisimov VN, Ukraintseva SV, Yashin AI. Cancer in rodents: does it tell us about cancer in humans? Nature reviews Cancer. 2005 Oct;5(10):807–19.
Anisimov, Vladimir N., et al. “Cancer in rodents: does it tell us about cancer in humans?” Nature Reviews. Cancer, vol. 5, no. 10, Oct. 2005, pp. 807–19. Epmc, doi:10.1038/nrc1715.
Anisimov VN, Ukraintseva SV, Yashin AI. Cancer in rodents: does it tell us about cancer in humans? Nature reviews Cancer. 2005 Oct;5(10):807–819.
Published In
Nature reviews. Cancer
DOI
EISSN
1474-1768
ISSN
1474-175X
Publication Date
October 2005
Volume
5
Issue
10
Start / End Page
807 / 819
Related Subject Headings
- Species Specificity
- Sex Characteristics
- Rodent Diseases
- Rats
- Oncology & Carcinogenesis
- Neoplasms
- Neoplasm Regression, Spontaneous
- Mice
- Male
- Incidence