Skip to main content

Variation method for inverse treatment planning

Publication ,  Journal Article
Liu, Y; Yin, FF; Gao, Q
Published in: Medical Physics
January 1, 1999

A new inverse planning method based on the theory of variation is developed for the computation of beam intensities that produce highly conformal dose distributions to the target volume that have an arbitrary complex geometry. It is shown that the objective function defined for the optimization of external beam intensities has a unique minimum. A corresponding algorithm is then designed to generate a sequence of intensity functions that converge to the minimum. The algorithm is applied to a test geometry where the target volume has concavity and there are adjacent critical organs. The cumulative dose-area histogram, the two-dimensional version of the cumulative dose-volume histogram, is used to evaluate the outcomes of this new inverse planning method. The results show that this method creates a group of intensity-modulated external beams that produce a dose distribution consistent with the given dose prescription.

Duke Scholars

Published In

Medical Physics

DOI

ISSN

0094-2405

Publication Date

January 1, 1999

Volume

26

Issue

3

Start / End Page

356 / 363

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Liu, Y., Yin, F. F., & Gao, Q. (1999). Variation method for inverse treatment planning. Medical Physics, 26(3), 356–363. https://doi.org/10.1118/1.598525
Liu, Y., F. F. Yin, and Q. Gao. “Variation method for inverse treatment planning.” Medical Physics 26, no. 3 (January 1, 1999): 356–63. https://doi.org/10.1118/1.598525.
Liu Y, Yin FF, Gao Q. Variation method for inverse treatment planning. Medical Physics. 1999 Jan 1;26(3):356–63.
Liu, Y., et al. “Variation method for inverse treatment planning.” Medical Physics, vol. 26, no. 3, Jan. 1999, pp. 356–63. Scopus, doi:10.1118/1.598525.
Liu Y, Yin FF, Gao Q. Variation method for inverse treatment planning. Medical Physics. 1999 Jan 1;26(3):356–363.

Published In

Medical Physics

DOI

ISSN

0094-2405

Publication Date

January 1, 1999

Volume

26

Issue

3

Start / End Page

356 / 363

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences