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Regulation of hematopoietic cell development and activation by adapter proteins.

Publication ,  Journal Article
Koretzky, GA; Abtahian, F; Derimanov, GS; Dmowski, SA; Guerriero, A; Jordan, MS; Maltzman, JS; Olenchock, BA; Singer, AL; Wu, JN; Zhong, X-P
Published in: Immunol Res
2003

Adapter proteins, molecules with modular domains that mediate intermolecular interactions, play critical roles in the regulation of signaling events in all cell types. A major focus of our laboratory has been to examine the role of adapter molecules in hematopoietic cell development and activation. This review will describe the approaches we are taking to identify such proteins and to determine the mechanisms by which they exert their functions. This work represents the enormous efforts of the students and postdocs who have committed themselves to these projects, as well as the important collaborations we have developed with other investigators at the University of Pennsylvania and elsewhere.

Duke Scholars

Published In

Immunol Res

DOI

ISSN

0257-277X

Publication Date

2003

Volume

27

Issue

2-3

Start / End Page

357 / 366

Location

United States

Related Subject Headings

  • T-Lymphocytes
  • Signal Transduction
  • Phosphoproteins
  • Immunology
  • Humans
  • Hematopoiesis
  • Animals
  • Adaptor Proteins, Signal Transducing
  • 3204 Immunology
  • 1107 Immunology
 

Citation

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MLA
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Koretzky, G. A., Abtahian, F., Derimanov, G. S., Dmowski, S. A., Guerriero, A., Jordan, M. S., … Zhong, X.-P. (2003). Regulation of hematopoietic cell development and activation by adapter proteins. Immunol Res, 27(2–3), 357–366. https://doi.org/10.1385/IR:27:2-3:357
Koretzky, Gary A., Farhad Abtahian, Geo S. Derimanov, Sally A. Dmowski, Anastasia Guerriero, Martha S. Jordan, Jonathan S. Maltzman, et al. “Regulation of hematopoietic cell development and activation by adapter proteins.Immunol Res 27, no. 2–3 (2003): 357–66. https://doi.org/10.1385/IR:27:2-3:357.
Koretzky GA, Abtahian F, Derimanov GS, Dmowski SA, Guerriero A, Jordan MS, et al. Regulation of hematopoietic cell development and activation by adapter proteins. Immunol Res. 2003;27(2–3):357–66.
Koretzky, Gary A., et al. “Regulation of hematopoietic cell development and activation by adapter proteins.Immunol Res, vol. 27, no. 2–3, 2003, pp. 357–66. Pubmed, doi:10.1385/IR:27:2-3:357.
Koretzky GA, Abtahian F, Derimanov GS, Dmowski SA, Guerriero A, Jordan MS, Maltzman JS, Olenchock BA, Singer AL, Wu JN, Zhong X-P. Regulation of hematopoietic cell development and activation by adapter proteins. Immunol Res. 2003;27(2–3):357–366.
Journal cover image

Published In

Immunol Res

DOI

ISSN

0257-277X

Publication Date

2003

Volume

27

Issue

2-3

Start / End Page

357 / 366

Location

United States

Related Subject Headings

  • T-Lymphocytes
  • Signal Transduction
  • Phosphoproteins
  • Immunology
  • Humans
  • Hematopoiesis
  • Animals
  • Adaptor Proteins, Signal Transducing
  • 3204 Immunology
  • 1107 Immunology