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Chronic primary intestinal pseudo-obstruction.

Publication ,  Journal Article
Hanks, JB; Meyers, WC; Andersen, DK; Woodard, BH; Peete, WP; Garbutt, JT; Jones, RS
Published in: Surgery
February 1981

Chronic primary intestinal pseudo-obstruction (CPIP) has received attention despite of its unclear etiology and infrequent occurrence. Recently a patient with this disorder had evidence of a primary visceral neuropathy. Reviewing the literature, we found 30 case reports of CPIP and evaluated their clinicopathologic findings. Presenting symptoms and radiologic findings were nonspecific. Esophageal motility was abnormal in 12 of 14 reports. Intestinal histopathology revealed normal muscle wall, mucosa, and ganglion cells in over 50% of reports. Only 48% of cases demonstrated clinical improvement. Thirty percent (8 of 30) ultimately died. We conclude that CPIP is a perplexing, often fatal entity that can mimic mechanical obstruction in the absence of definite etiology. Primary neurologic or muscular disease may be a possible explanation, but, as yet, definite documentation does not exist.

Duke Scholars

Published In

Surgery

ISSN

0039-6060

Publication Date

February 1981

Volume

89

Issue

2

Start / End Page

175 / 182

Location

United States

Related Subject Headings

  • Surgery
  • Middle Aged
  • Male
  • Intestinal Pseudo-Obstruction
  • Intestinal Obstruction
  • Infant
  • Humans
  • Female
  • Esophagus
  • Chronic Disease
 

Citation

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Hanks, J. B., Meyers, W. C., Andersen, D. K., Woodard, B. H., Peete, W. P., Garbutt, J. T., & Jones, R. S. (1981). Chronic primary intestinal pseudo-obstruction. Surgery, 89(2), 175–182.
Hanks, J. B., W. C. Meyers, D. K. Andersen, B. H. Woodard, W. P. Peete, J. T. Garbutt, and R. S. Jones. “Chronic primary intestinal pseudo-obstruction.Surgery 89, no. 2 (February 1981): 175–82.
Hanks JB, Meyers WC, Andersen DK, Woodard BH, Peete WP, Garbutt JT, et al. Chronic primary intestinal pseudo-obstruction. Surgery. 1981 Feb;89(2):175–82.
Hanks, J. B., et al. “Chronic primary intestinal pseudo-obstruction.Surgery, vol. 89, no. 2, Feb. 1981, pp. 175–82.
Hanks JB, Meyers WC, Andersen DK, Woodard BH, Peete WP, Garbutt JT, Jones RS. Chronic primary intestinal pseudo-obstruction. Surgery. 1981 Feb;89(2):175–182.
Journal cover image

Published In

Surgery

ISSN

0039-6060

Publication Date

February 1981

Volume

89

Issue

2

Start / End Page

175 / 182

Location

United States

Related Subject Headings

  • Surgery
  • Middle Aged
  • Male
  • Intestinal Pseudo-Obstruction
  • Intestinal Obstruction
  • Infant
  • Humans
  • Female
  • Esophagus
  • Chronic Disease