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Onset of dyskinesia and changes in postural task performance during the course of neuroleptic withdrawal.

Publication ,  Journal Article
Newell, KM; Ko, YG; Sprague, RL; Mahorney, SL; Bodfish, JW
Published in: Am J Ment Retard
July 2002

The effect of neuroleptic withdrawal on postural task performance of 20 adults with mental retardation was examined. Dyskinesia was measured using the DISCUS rating scale and postural stability using a force platform during a prospective longitudinal neuroleptic medication withdrawal protocol. Assessments were conducted at baseline and monthly intervals, extending to approximately one year following complete medication withdrawal, when significant changes in amount of postural motion and sequential pattern of postural movement complexity were observed. Postural task performance tended to return to near baseline levels at periods of up to 1 year following medication withdrawal, although one third of the subjects continued to display atypical postural motion profiles at follow-up. Results provide within-subject evidence that tardive dyskinesia is associated with generalized changes in motor control and not simply peripheral disturbances of movement.

Duke Scholars

Published In

Am J Ment Retard

DOI

ISSN

0895-8017

Publication Date

July 2002

Volume

107

Issue

4

Start / End Page

270 / 277

Location

United States

Related Subject Headings

  • Time Factors
  • Task Performance and Analysis
  • Substance Withdrawal Syndrome
  • Sampling Studies
  • Rehabilitation
  • Posture
  • Intellectual Disability
  • Humans
  • Dyskinesia, Drug-Induced
  • Antipsychotic Agents
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Newell, K. M., Ko, Y. G., Sprague, R. L., Mahorney, S. L., & Bodfish, J. W. (2002). Onset of dyskinesia and changes in postural task performance during the course of neuroleptic withdrawal. Am J Ment Retard, 107(4), 270–277. https://doi.org/10.1352/0895-8017(2002)107<0270:OODACI>2.0.CO;2
Newell, Karl M., Young G. Ko, Robert L. Sprague, Steven L. Mahorney, and James W. Bodfish. “Onset of dyskinesia and changes in postural task performance during the course of neuroleptic withdrawal.Am J Ment Retard 107, no. 4 (July 2002): 270–77. https://doi.org/10.1352/0895-8017(2002)107<0270:OODACI>2.0.CO;2.
Newell KM, Ko YG, Sprague RL, Mahorney SL, Bodfish JW. Onset of dyskinesia and changes in postural task performance during the course of neuroleptic withdrawal. Am J Ment Retard. 2002 Jul;107(4):270–7.
Newell, Karl M., et al. “Onset of dyskinesia and changes in postural task performance during the course of neuroleptic withdrawal.Am J Ment Retard, vol. 107, no. 4, July 2002, pp. 270–77. Pubmed, doi:10.1352/0895-8017(2002)107<0270:OODACI>2.0.CO;2.
Newell KM, Ko YG, Sprague RL, Mahorney SL, Bodfish JW. Onset of dyskinesia and changes in postural task performance during the course of neuroleptic withdrawal. Am J Ment Retard. 2002 Jul;107(4):270–277.

Published In

Am J Ment Retard

DOI

ISSN

0895-8017

Publication Date

July 2002

Volume

107

Issue

4

Start / End Page

270 / 277

Location

United States

Related Subject Headings

  • Time Factors
  • Task Performance and Analysis
  • Substance Withdrawal Syndrome
  • Sampling Studies
  • Rehabilitation
  • Posture
  • Intellectual Disability
  • Humans
  • Dyskinesia, Drug-Induced
  • Antipsychotic Agents