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Emerging insights into the genesis of epilepsy.

Publication ,  Journal Article
McNamara, JO
Published in: Nature
June 24, 1999

Epilepsies are a diverse collection of brain disorders that affect 1-2% of the population. Current therapies are unsatisfactory as they provide only symptomatic relief, are effective in only a subset of affected individuals, and are often accompanied by persistent toxic effects. It is hoped that insight into the cellular and molecular mechanisms of epileptogenesis will lead to new therapies, prevention, or even a cure. Emerging insights point to alterations of synaptic function and intrinsic properties of neurons as common mechanisms underlying the hyperexcitability in diverse forms of epilepsy.

Duke Scholars

Published In

Nature

DOI

ISSN

0028-0836

Publication Date

June 24, 1999

Volume

399

Issue

6738 Suppl

Start / End Page

A15 / A22

Location

England

Related Subject Headings

  • Neurons
  • Humans
  • General Science & Technology
  • Forecasting
  • Epilepsy
  • Brain Injuries
  • Axons
  • Autoimmune Diseases
  • Animals
 

Citation

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ICMJE
MLA
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McNamara, J. O. (1999). Emerging insights into the genesis of epilepsy. Nature, 399(6738 Suppl), A15–A22. https://doi.org/10.1038/399a015
McNamara, J. O. “Emerging insights into the genesis of epilepsy.Nature 399, no. 6738 Suppl (June 24, 1999): A15–22. https://doi.org/10.1038/399a015.
McNamara JO. Emerging insights into the genesis of epilepsy. Nature. 1999 Jun 24;399(6738 Suppl):A15–22.
McNamara, J. O. “Emerging insights into the genesis of epilepsy.Nature, vol. 399, no. 6738 Suppl, June 1999, pp. A15–22. Pubmed, doi:10.1038/399a015.
McNamara JO. Emerging insights into the genesis of epilepsy. Nature. 1999 Jun 24;399(6738 Suppl):A15–A22.
Journal cover image

Published In

Nature

DOI

ISSN

0028-0836

Publication Date

June 24, 1999

Volume

399

Issue

6738 Suppl

Start / End Page

A15 / A22

Location

England

Related Subject Headings

  • Neurons
  • Humans
  • General Science & Technology
  • Forecasting
  • Epilepsy
  • Brain Injuries
  • Axons
  • Autoimmune Diseases
  • Animals