NO: an inhibitor of cell death.
Publication
, Journal Article
Liu, L; Stamler, JS
Published in: Cell death and differentiation
October 1999
Nitric oxide (NO) or related molecules of both endogenous and exogenous origin inhibit programmed cell death in a variety of cells and tissues. This general protective function is largely independent of the apoptotic stimulus. S-nitrosylation of the catalytic-site cysteine of caspases is a well-established and possibly widespread mechanism of enzyme inhibition that protects from cell death. However, NO may inhibit apoptosis by additional mechanisms. The physiological and pathological significance of NO's anti-apoptotic activity remains to be determined in most cases.
Published In
Cell death and differentiation
DOI
EISSN
1476-5403
ISSN
1350-9047
Publication Date
October 1999
Volume
6
Issue
10
Start / End Page
937 / 942
Related Subject Headings
- Nitric Oxide
- Humans
- Cytoprotection
- Cell Death
- Biochemistry & Molecular Biology
- Animals
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 11 Medical and Health Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Liu, L., & Stamler, J. S. (1999). NO: an inhibitor of cell death. Cell Death and Differentiation, 6(10), 937–942. https://doi.org/10.1038/sj.cdd.4400578
Liu, L., and J. S. Stamler. “NO: an inhibitor of cell death.” Cell Death and Differentiation 6, no. 10 (October 1999): 937–42. https://doi.org/10.1038/sj.cdd.4400578.
Liu L, Stamler JS. NO: an inhibitor of cell death. Cell death and differentiation. 1999 Oct;6(10):937–42.
Liu, L., and J. S. Stamler. “NO: an inhibitor of cell death.” Cell Death and Differentiation, vol. 6, no. 10, Oct. 1999, pp. 937–42. Epmc, doi:10.1038/sj.cdd.4400578.
Liu L, Stamler JS. NO: an inhibitor of cell death. Cell death and differentiation. 1999 Oct;6(10):937–942.
Published In
Cell death and differentiation
DOI
EISSN
1476-5403
ISSN
1350-9047
Publication Date
October 1999
Volume
6
Issue
10
Start / End Page
937 / 942
Related Subject Headings
- Nitric Oxide
- Humans
- Cytoprotection
- Cell Death
- Biochemistry & Molecular Biology
- Animals
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 11 Medical and Health Sciences