Morphological and biochemical properties of a new human breast cancer cell line.
Publication
, Journal Article
Langlois, AJ; Holder, WD; Iglehart, JD; Nelson-Rees, WA; Wells, SA; Bolognesi, DP
Published in: Cancer Res
July 1979
DU4475 is a new human breast cell line derived from a cutaneous metastatic nodule from a patient with advanced breast cancer. It has been in continuous culture for more than 1 year and has survived 140 subcultivations. The cells grow in suspension, displaying clusters and free-floating aggregates with serpentine-like outgrowths. The cell line is hypotetraploid with modal chromosome numbers between 86 and 93 and possesses five to six distinctive marker chromosomes. The cells grow readily in athymic nude mice and produce tumors from which cells can be reintroduced to culture in vitro.
Duke Scholars
Published In
Cancer Res
ISSN
0008-5472
Publication Date
July 1979
Volume
39
Issue
7 Pt 1
Start / End Page
2604 / 2613
Location
United States
Related Subject Headings
- Transplantation, Heterologous
- Receptors, Cell Surface
- Oncology & Carcinogenesis
- Neoplasm Transplantation
- Isoenzymes
- Humans
- Glucosephosphate Dehydrogenase
- Female
- Chromosomes
- Cell Line
Citation
APA
Chicago
ICMJE
MLA
NLM
Langlois, A. J., Holder, W. D., Iglehart, J. D., Nelson-Rees, W. A., Wells, S. A., & Bolognesi, D. P. (1979). Morphological and biochemical properties of a new human breast cancer cell line. Cancer Res, 39(7 Pt 1), 2604–2613.
Langlois, A. J., W. D. Holder, J. D. Iglehart, W. A. Nelson-Rees, S. A. Wells, and D. P. Bolognesi. “Morphological and biochemical properties of a new human breast cancer cell line.” Cancer Res 39, no. 7 Pt 1 (July 1979): 2604–13.
Langlois AJ, Holder WD, Iglehart JD, Nelson-Rees WA, Wells SA, Bolognesi DP. Morphological and biochemical properties of a new human breast cancer cell line. Cancer Res. 1979 Jul;39(7 Pt 1):2604–13.
Langlois, A. J., et al. “Morphological and biochemical properties of a new human breast cancer cell line.” Cancer Res, vol. 39, no. 7 Pt 1, July 1979, pp. 2604–13.
Langlois AJ, Holder WD, Iglehart JD, Nelson-Rees WA, Wells SA, Bolognesi DP. Morphological and biochemical properties of a new human breast cancer cell line. Cancer Res. 1979 Jul;39(7 Pt 1):2604–2613.
Published In
Cancer Res
ISSN
0008-5472
Publication Date
July 1979
Volume
39
Issue
7 Pt 1
Start / End Page
2604 / 2613
Location
United States
Related Subject Headings
- Transplantation, Heterologous
- Receptors, Cell Surface
- Oncology & Carcinogenesis
- Neoplasm Transplantation
- Isoenzymes
- Humans
- Glucosephosphate Dehydrogenase
- Female
- Chromosomes
- Cell Line