Rational theophylline use in older asthmatics.
Publication
, Journal Article
Koenig, HG; Blake, RL
Published in: Geriatrics
August 1986
In the sick adult, the variability of clearance from patient to patient may be greater than 50%. A given dose of theophylline that is predicted to result in a serum concentration of 15 micrograms/ml may result in an actual range of serum concentrations from 6.6 to 33 micrograms/ml. Respiratory infections, both acute and chronic, seem to have an adverse effect on theophylline clearance. Studies in adults with acute viral upper respiratory infections, pneumonia, and chronic obstructive pulmonary disease show a significant decrease in clearance.
Duke Scholars
Published In
Geriatrics
ISSN
0016-867X
Publication Date
August 1986
Volume
41
Issue
8
Start / End Page
49 / 55
Location
United States
Related Subject Headings
- Theophylline
- Smoking
- Middle Aged
- Kinetics
- Humans
- Geriatrics
- Female
- Drug Interactions
- Asthma
- Anti-Bacterial Agents
Citation
APA
Chicago
ICMJE
MLA
NLM
Koenig, H. G., & Blake, R. L. (1986). Rational theophylline use in older asthmatics. Geriatrics, 41(8), 49–55.
Koenig, H. G., and R. L. Blake. “Rational theophylline use in older asthmatics.” Geriatrics 41, no. 8 (August 1986): 49–55.
Koenig HG, Blake RL. Rational theophylline use in older asthmatics. Geriatrics. 1986 Aug;41(8):49–55.
Koenig, H. G., and R. L. Blake. “Rational theophylline use in older asthmatics.” Geriatrics, vol. 41, no. 8, Aug. 1986, pp. 49–55.
Koenig HG, Blake RL. Rational theophylline use in older asthmatics. Geriatrics. 1986 Aug;41(8):49–55.
Published In
Geriatrics
ISSN
0016-867X
Publication Date
August 1986
Volume
41
Issue
8
Start / End Page
49 / 55
Location
United States
Related Subject Headings
- Theophylline
- Smoking
- Middle Aged
- Kinetics
- Humans
- Geriatrics
- Female
- Drug Interactions
- Asthma
- Anti-Bacterial Agents