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A neuroanatomic model for depression.

Publication ,  Journal Article
Byrum, CE; Ahearn, EP; Krishnan, KR
Published in: Prog Neuropsychopharmacol Biol Psychiatry
February 1999

1. Emotion and mood, once thought to be governed solely by the limbic system of the brain, now are thought to be influenced by numerous nonlimbic central nervous system structures as well. 2. The present review discusses several important brain structures and neuroanatomic pathways thought to be involved in affect and mood disorders, including the amygdala, frontal neocortex, cingulate gyrus, basal ganglia, and the monoamine systems. 3. The authors propose a specific neuroanatomic model for depression that emphasizes that a distributed system of extensively interconnected CNS structures mediates emotion and affect.

Duke Scholars

Published In

Prog Neuropsychopharmacol Biol Psychiatry

DOI

ISSN

0278-5846

Publication Date

February 1999

Volume

23

Issue

2

Start / End Page

175 / 193

Location

England

Related Subject Headings

  • Psychiatry
  • Neocortex
  • Humans
  • Gyrus Cinguli
  • Emotions
  • Depressive Disorder
  • Brain
  • Biogenic Monoamines
  • Basal Ganglia
  • Amygdala
 

Citation

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ICMJE
MLA
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Byrum, C. E., Ahearn, E. P., & Krishnan, K. R. (1999). A neuroanatomic model for depression. Prog Neuropsychopharmacol Biol Psychiatry, 23(2), 175–193. https://doi.org/10.1016/s0278-5846(98)00106-7
Byrum, C. E., E. P. Ahearn, and K. R. Krishnan. “A neuroanatomic model for depression.Prog Neuropsychopharmacol Biol Psychiatry 23, no. 2 (February 1999): 175–93. https://doi.org/10.1016/s0278-5846(98)00106-7.
Byrum CE, Ahearn EP, Krishnan KR. A neuroanatomic model for depression. Prog Neuropsychopharmacol Biol Psychiatry. 1999 Feb;23(2):175–93.
Byrum, C. E., et al. “A neuroanatomic model for depression.Prog Neuropsychopharmacol Biol Psychiatry, vol. 23, no. 2, Feb. 1999, pp. 175–93. Pubmed, doi:10.1016/s0278-5846(98)00106-7.
Byrum CE, Ahearn EP, Krishnan KR. A neuroanatomic model for depression. Prog Neuropsychopharmacol Biol Psychiatry. 1999 Feb;23(2):175–193.
Journal cover image

Published In

Prog Neuropsychopharmacol Biol Psychiatry

DOI

ISSN

0278-5846

Publication Date

February 1999

Volume

23

Issue

2

Start / End Page

175 / 193

Location

England

Related Subject Headings

  • Psychiatry
  • Neocortex
  • Humans
  • Gyrus Cinguli
  • Emotions
  • Depressive Disorder
  • Brain
  • Biogenic Monoamines
  • Basal Ganglia
  • Amygdala