Atypical antidopaminergic properties of CI-686: a potential antipsychotic agent.
Publication
, Journal Article
Stanley, M; Rotrosen, J; Sculerati, N; Gershon, S; Kuhn, C; Cohen, BM
Published in: Psychopharmacology (Berl)
1979
The effects of the antipsychotic/antidepressant drug CI-686 on apomorphine- and amphetamine-induced stereotypies, dopamine metabolism, neuroleptic binding, and serum prolactin levels were determined. CI-686 displayed profiles of activity in each of these systems that differs markedly from those of other antipsychotics. CI-686's unique preclinical profile suggests a mechanism of action other than dopamine antagonism which could have implications regarding current thinking on the pathophysiology of schizophrenia.
Duke Scholars
Published In
Psychopharmacology (Berl)
DOI
ISSN
0033-3158
Publication Date
1979
Volume
66
Issue
1
Start / End Page
23 / 27
Location
Germany
Related Subject Headings
- Stereotyped Behavior
- Rats
- Radioligand Assay
- Psychiatry
- Prolactin
- Male
- Humans
- Dopamine Antagonists
- Chromans
- Binding, Competitive
Citation
APA
Chicago
ICMJE
MLA
NLM
Stanley, M., Rotrosen, J., Sculerati, N., Gershon, S., Kuhn, C., & Cohen, B. M. (1979). Atypical antidopaminergic properties of CI-686: a potential antipsychotic agent. Psychopharmacology (Berl), 66(1), 23–27. https://doi.org/10.1007/BF00431984
Stanley, M., J. Rotrosen, N. Sculerati, S. Gershon, C. Kuhn, and B. M. Cohen. “Atypical antidopaminergic properties of CI-686: a potential antipsychotic agent.” Psychopharmacology (Berl) 66, no. 1 (1979): 23–27. https://doi.org/10.1007/BF00431984.
Stanley M, Rotrosen J, Sculerati N, Gershon S, Kuhn C, Cohen BM. Atypical antidopaminergic properties of CI-686: a potential antipsychotic agent. Psychopharmacology (Berl). 1979;66(1):23–7.
Stanley, M., et al. “Atypical antidopaminergic properties of CI-686: a potential antipsychotic agent.” Psychopharmacology (Berl), vol. 66, no. 1, 1979, pp. 23–27. Pubmed, doi:10.1007/BF00431984.
Stanley M, Rotrosen J, Sculerati N, Gershon S, Kuhn C, Cohen BM. Atypical antidopaminergic properties of CI-686: a potential antipsychotic agent. Psychopharmacology (Berl). 1979;66(1):23–27.
Published In
Psychopharmacology (Berl)
DOI
ISSN
0033-3158
Publication Date
1979
Volume
66
Issue
1
Start / End Page
23 / 27
Location
Germany
Related Subject Headings
- Stereotyped Behavior
- Rats
- Radioligand Assay
- Psychiatry
- Prolactin
- Male
- Humans
- Dopamine Antagonists
- Chromans
- Binding, Competitive