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Extending the detectability index to quantitative imaging performance: Applications in tomosynthesis and CT

Publication ,  Conference
Richard, S; Chen, B; Samei, E
Published in: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
December 1, 2010

This study aimed to extend Fourier-based imaging metrics for the modeling of quantitative imaging performance. Breast tomosynthesis was used as a platform for investigating acquisition and processing parameters (e.g., acquisition angle and dose) that can significantly affect 3D signal and noise, and consequently quantitative imaging performance. The detectability index was computed using the modulation transfer function and noise-power spectrum combined with a Fourier description of imaging task. Three imaging tasks were considered: detection, area estimation (in coronal slice), and volume estimation of a 4 mm diameter spherical target. Task functions for size estimation were generated by using measured performance of the maximum-likelihood estimator as training data. The detectability index computed with the size estimation tasks correlated well with precision measurements for area and volume estimation over a fairly broad range of imaging conditions and provided a meaningful figure of merit for quantitative imaging performance. Furthermore, results highlighted that optimal breast tomosynthesis acquisition parameters depend significantly on imaging task. Mass detection was optimal at an acquisition angle of 85" while area and volume estimation for the same mass were optimal at ∼100" and 125° acquisition angles, respectively. These findings provide key initial validation that the Fourier-based detectability index extended to estimation tasks can represent a meaningful metric and predictor of quantitative imaging performance. © 2010 SPIE.

Duke Scholars

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

ISBN

9780819480231

Publication Date

December 1, 2010

Volume

7622

Issue

PART 1
 

Citation

APA
Chicago
ICMJE
MLA
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Richard, S., Chen, B., & Samei, E. (2010). Extending the detectability index to quantitative imaging performance: Applications in tomosynthesis and CT. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7622). https://doi.org/10.1117/12.845286
Richard, S., B. Chen, and E. Samei. “Extending the detectability index to quantitative imaging performance: Applications in tomosynthesis and CT.” In Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 7622, 2010. https://doi.org/10.1117/12.845286.
Richard S, Chen B, Samei E. Extending the detectability index to quantitative imaging performance: Applications in tomosynthesis and CT. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2010.
Richard, S., et al. “Extending the detectability index to quantitative imaging performance: Applications in tomosynthesis and CT.” Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 7622, no. PART 1, 2010. Scopus, doi:10.1117/12.845286.
Richard S, Chen B, Samei E. Extending the detectability index to quantitative imaging performance: Applications in tomosynthesis and CT. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2010.
Journal cover image

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

ISBN

9780819480231

Publication Date

December 1, 2010

Volume

7622

Issue

PART 1