Acute kidney injury in HIV-infected patients.
Acute kidney injury is common in human immunodeficiency virus (HIV)-infected patients, and has been associated with increased morbidity and mortality. Before the introduction of effective antiretroviral therapy, acute kidney injury in HIV-positive patients was most commonly the result of volume depletion, septicemia, or nephrotoxic medications. Acute kidney injury remains a significant problem in the antiretroviral era, and still commonly is attributed to infection or nephrotoxic medications. Less common causes such as direct infectious insults, immune restoration inflammatory syndrome, rhabdomyolysis, and obstruction should be considered when the underlying process is not obvious. In addition to advanced HIV disease, several other patient characteristics have emerged as potential risk factors for acute kidney injury in the antiretroviral era, including older age, diabetes, pre-existing chronic kidney disease, and hepatitis co-infection or liver disease.
Duke Scholars
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Related Subject Headings
- Urology & Nephrology
- United States
- Survival Rate
- Risk Factors
- Morbidity
- Kidney Cortex Necrosis
- Humans
- HIV Infections
- Acute Kidney Injury
- 3202 Clinical sciences
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Urology & Nephrology
- United States
- Survival Rate
- Risk Factors
- Morbidity
- Kidney Cortex Necrosis
- Humans
- HIV Infections
- Acute Kidney Injury
- 3202 Clinical sciences