Skip to main content

The continued vital role of electron microscopy in the diagnosis of renal disease/dysfunction.

Publication ,  Journal Article
Pavlisko, EN; Howell, DN
Published in: Ultrastruct Pathol
February 2013

Ultrastructural examination remains a crucial diagnostic tool for analysis of renal biopsies, along with light and immunofluorescence microscopy. Several advantages of electron microscopy are the ability to detect most forms of glomerular disease/dysfunction; the ability to examine small, suboptimal, or unusual specimens; and superior resolution that allows the investigator to hunt without preconceived ideas of what he/she is looking for or will find. A few shortcomings must be noted for completeness, including inability to detect disorders without specific ultrastructural signature, biochemical heterogeneity of deposits with similar or identical ultrastructural appearances, and occasional false-negative results in diseases with focal manifestations.

Duke Scholars

Published In

Ultrastruct Pathol

DOI

EISSN

1521-0758

Publication Date

February 2013

Volume

37

Issue

1

Start / End Page

1 / 8

Location

England

Related Subject Headings

  • Predictive Value of Tests
  • Pathology
  • Microscopy, Electron
  • Kidney Diseases
  • Kidney
  • Humans
  • False Negative Reactions
  • Biopsy
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Pavlisko, E. N., & Howell, D. N. (2013). The continued vital role of electron microscopy in the diagnosis of renal disease/dysfunction. Ultrastruct Pathol, 37(1), 1–8. https://doi.org/10.3109/01913123.2012.670025
Pavlisko, Elizabeth N., and David N. Howell. “The continued vital role of electron microscopy in the diagnosis of renal disease/dysfunction.Ultrastruct Pathol 37, no. 1 (February 2013): 1–8. https://doi.org/10.3109/01913123.2012.670025.
Pavlisko EN, Howell DN. The continued vital role of electron microscopy in the diagnosis of renal disease/dysfunction. Ultrastruct Pathol. 2013 Feb;37(1):1–8.
Pavlisko, Elizabeth N., and David N. Howell. “The continued vital role of electron microscopy in the diagnosis of renal disease/dysfunction.Ultrastruct Pathol, vol. 37, no. 1, Feb. 2013, pp. 1–8. Pubmed, doi:10.3109/01913123.2012.670025.
Pavlisko EN, Howell DN. The continued vital role of electron microscopy in the diagnosis of renal disease/dysfunction. Ultrastruct Pathol. 2013 Feb;37(1):1–8.

Published In

Ultrastruct Pathol

DOI

EISSN

1521-0758

Publication Date

February 2013

Volume

37

Issue

1

Start / End Page

1 / 8

Location

England

Related Subject Headings

  • Predictive Value of Tests
  • Pathology
  • Microscopy, Electron
  • Kidney Diseases
  • Kidney
  • Humans
  • False Negative Reactions
  • Biopsy
  • 3202 Clinical sciences
  • 1103 Clinical Sciences