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Bathing the brain.

Publication ,  Journal Article
Strittmatter, WJ
Published in: J Clin Invest
March 2013

The brain and spinal cord are surrounded by cerebrospinal fluid, which provides a mechanically stable environment for these delicate structures against the forces of gravity and sudden acceleration and deceleration. Neurons and glia comprising the parenchyma of the brain are enveloped in their microenvironment by interstitial fluid. Interstitial fluid has long been considered to be unaffected by the production and flow of cerebrospinal fluid outside the brain parenchyma. However, two recent papers by Iliff et al. demonstrate that cerebrospinal fluid enters the deep substance of the brain, mixes with the interstitial fluid surrounding neurons and glia, and plays an important role in the exchange and clearance of molecules in the interstitial space of the central nervous system.

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Published In

J Clin Invest

DOI

EISSN

1558-8238

Publication Date

March 2013

Volume

123

Issue

3

Start / End Page

1013 / 1015

Location

United States

Related Subject Headings

  • Magnetic Resonance Imaging
  • Immunology
  • Humans
  • Gadolinium DTPA
  • Female
  • Contrast Media
  • Brain
  • Animals
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Strittmatter, W. J. (2013). Bathing the brain. J Clin Invest, 123(3), 1013–1015. https://doi.org/10.1172/JCI68241
Strittmatter, Warren J. “Bathing the brain.J Clin Invest 123, no. 3 (March 2013): 1013–15. https://doi.org/10.1172/JCI68241.
Strittmatter WJ. Bathing the brain. J Clin Invest. 2013 Mar;123(3):1013–5.
Strittmatter, Warren J. “Bathing the brain.J Clin Invest, vol. 123, no. 3, Mar. 2013, pp. 1013–15. Pubmed, doi:10.1172/JCI68241.
Strittmatter WJ. Bathing the brain. J Clin Invest. 2013 Mar;123(3):1013–1015.

Published In

J Clin Invest

DOI

EISSN

1558-8238

Publication Date

March 2013

Volume

123

Issue

3

Start / End Page

1013 / 1015

Location

United States

Related Subject Headings

  • Magnetic Resonance Imaging
  • Immunology
  • Humans
  • Gadolinium DTPA
  • Female
  • Contrast Media
  • Brain
  • Animals
  • 42 Health sciences
  • 32 Biomedical and clinical sciences