Efficient trial designs to reduce placebo requirements.
Publication
, Journal Article
Krishnan, KR
Published in: Biol Psychiatry
April 15, 2000
This brief discussion summarizes possible trial design changes that could be utilized to reduce the number of subjects exposed to ineffective treatment--in this case placebo; however, these designs are fairly complex and have not been implemented sufficiently to judge their utility. Clearly, such studies are essential before embarking on these paradigms as a primary method for assessing antidepressant efficacy.
Duke Scholars
Published In
Biol Psychiatry
DOI
ISSN
0006-3223
Publication Date
April 15, 2000
Volume
47
Issue
8
Start / End Page
724 / 726
Location
United States
Related Subject Headings
- Treatment Outcome
- Psychiatry
- Placebos
- Humans
- Depression
- Clinical Trials as Topic
- Antidepressive Agents
- 52 Psychology
- 32 Biomedical and clinical sciences
- 31 Biological sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Krishnan, K. R. (2000). Efficient trial designs to reduce placebo requirements. Biol Psychiatry, 47(8), 724–726. https://doi.org/10.1016/s0006-3223(99)00320-0
Krishnan, K. R. “Efficient trial designs to reduce placebo requirements.” Biol Psychiatry 47, no. 8 (April 15, 2000): 724–26. https://doi.org/10.1016/s0006-3223(99)00320-0.
Krishnan KR. Efficient trial designs to reduce placebo requirements. Biol Psychiatry. 2000 Apr 15;47(8):724–6.
Krishnan, K. R. “Efficient trial designs to reduce placebo requirements.” Biol Psychiatry, vol. 47, no. 8, Apr. 2000, pp. 724–26. Pubmed, doi:10.1016/s0006-3223(99)00320-0.
Krishnan KR. Efficient trial designs to reduce placebo requirements. Biol Psychiatry. 2000 Apr 15;47(8):724–726.
Published In
Biol Psychiatry
DOI
ISSN
0006-3223
Publication Date
April 15, 2000
Volume
47
Issue
8
Start / End Page
724 / 726
Location
United States
Related Subject Headings
- Treatment Outcome
- Psychiatry
- Placebos
- Humans
- Depression
- Clinical Trials as Topic
- Antidepressive Agents
- 52 Psychology
- 32 Biomedical and clinical sciences
- 31 Biological sciences