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Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis.

Publication ,  Journal Article
Glickfeld, LL; Roberts, JD; Somogyi, P; Scanziani, M
Published in: Nat Neurosci
January 2009

Although GABAergic interneurons are the main source of synaptic inhibition in the cortex, activation of GABA(A) receptors has been shown to depolarize specific neuronal compartments, resulting in excitation. By using a noninvasive approach to monitor the effect of individual interneurons on the pyramidal cell population, we found that rat hippocampal interneurons hyperpolarized pyramidal cells irrespective of the location of their synapses along the somato-dendritic axis.

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Published In

Nat Neurosci

DOI

EISSN

1546-1726

Publication Date

January 2009

Volume

12

Issue

1

Start / End Page

21 / 23

Location

United States

Related Subject Headings

  • gamma-Aminobutyric Acid
  • Synaptic Transmission
  • Receptors, GABA-A
  • Rats
  • Pyramidal Cells
  • Neurology & Neurosurgery
  • Interneurons
  • Hippocampus
  • Electrophysiology
  • Dendrites
 

Citation

APA
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ICMJE
MLA
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Glickfeld, L. L., Roberts, J. D., Somogyi, P., & Scanziani, M. (2009). Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. Nat Neurosci, 12(1), 21–23. https://doi.org/10.1038/nn.2230
Glickfeld, Lindsey L., J David Roberts, Peter Somogyi, and Massimo Scanziani. “Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis.Nat Neurosci 12, no. 1 (January 2009): 21–23. https://doi.org/10.1038/nn.2230.
Glickfeld LL, Roberts JD, Somogyi P, Scanziani M. Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. Nat Neurosci. 2009 Jan;12(1):21–3.
Glickfeld, Lindsey L., et al. “Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis.Nat Neurosci, vol. 12, no. 1, Jan. 2009, pp. 21–23. Pubmed, doi:10.1038/nn.2230.
Glickfeld LL, Roberts JD, Somogyi P, Scanziani M. Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. Nat Neurosci. 2009 Jan;12(1):21–23.

Published In

Nat Neurosci

DOI

EISSN

1546-1726

Publication Date

January 2009

Volume

12

Issue

1

Start / End Page

21 / 23

Location

United States

Related Subject Headings

  • gamma-Aminobutyric Acid
  • Synaptic Transmission
  • Receptors, GABA-A
  • Rats
  • Pyramidal Cells
  • Neurology & Neurosurgery
  • Interneurons
  • Hippocampus
  • Electrophysiology
  • Dendrites