Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis.
Publication
, Journal Article
Glickfeld, LL; Roberts, JD; Somogyi, P; Scanziani, M
Published in: Nat Neurosci
January 2009
Although GABAergic interneurons are the main source of synaptic inhibition in the cortex, activation of GABA(A) receptors has been shown to depolarize specific neuronal compartments, resulting in excitation. By using a noninvasive approach to monitor the effect of individual interneurons on the pyramidal cell population, we found that rat hippocampal interneurons hyperpolarized pyramidal cells irrespective of the location of their synapses along the somato-dendritic axis.
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Published In
Nat Neurosci
DOI
EISSN
1546-1726
Publication Date
January 2009
Volume
12
Issue
1
Start / End Page
21 / 23
Location
United States
Related Subject Headings
- gamma-Aminobutyric Acid
- Synaptic Transmission
- Receptors, GABA-A
- Rats
- Pyramidal Cells
- Neurology & Neurosurgery
- Interneurons
- Hippocampus
- Electrophysiology
- Dendrites
Citation
APA
Chicago
ICMJE
MLA
NLM
Glickfeld, L. L., Roberts, J. D., Somogyi, P., & Scanziani, M. (2009). Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. Nat Neurosci, 12(1), 21–23. https://doi.org/10.1038/nn.2230
Glickfeld, Lindsey L., J David Roberts, Peter Somogyi, and Massimo Scanziani. “Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis.” Nat Neurosci 12, no. 1 (January 2009): 21–23. https://doi.org/10.1038/nn.2230.
Glickfeld LL, Roberts JD, Somogyi P, Scanziani M. Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. Nat Neurosci. 2009 Jan;12(1):21–3.
Glickfeld, Lindsey L., et al. “Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis.” Nat Neurosci, vol. 12, no. 1, Jan. 2009, pp. 21–23. Pubmed, doi:10.1038/nn.2230.
Glickfeld LL, Roberts JD, Somogyi P, Scanziani M. Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. Nat Neurosci. 2009 Jan;12(1):21–23.
Published In
Nat Neurosci
DOI
EISSN
1546-1726
Publication Date
January 2009
Volume
12
Issue
1
Start / End Page
21 / 23
Location
United States
Related Subject Headings
- gamma-Aminobutyric Acid
- Synaptic Transmission
- Receptors, GABA-A
- Rats
- Pyramidal Cells
- Neurology & Neurosurgery
- Interneurons
- Hippocampus
- Electrophysiology
- Dendrites