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Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose?

Publication ,  Journal Article
Luke, FE; Allen, BC; Moshiri, ST; Ho, LM; Massey, CM; Stinnett, SS; Muir, AJ; Jaffe, TA
Published in: J Comput Assist Tomogr
2013

OBJECTIVE: The objectives of this study were to explore utilization of multi-detector row computed tomography (MDCT) in screening for hepatocellular carcinoma (HCC) and to modify a liver CT protocol with a goal of dose reduction. METHODS: An electronic mail survey querying HCC surveillance practices was sent. One hundred forty consecutive patients referred for HCC indications underwent 4-phase MDCT of the liver. The unenhanced and delayed phases were evaluated by 3 readers for identification of HCC and reader confidence. The estimated effective dose (ED) was calculated. RESULTS: Computed tomography is primarily used to screen for HCC. Average estimated ED was 35.5 mSv. Unenhanced phase did not add to reader confidence; delayed phase increased confidence in 47% of cases. Thirty-two percent of the screening population had cumulative ED of greater than 200 mSv. CONCLUSIONS: Multi-detector row CT of the liver is used frequently in screening for HCC. Unenhanced phase imaging does not add to HCC detection and may be eliminated to reduce radiation dose.

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Published In

J Comput Assist Tomogr

DOI

EISSN

1532-3145

Publication Date

2013

Volume

37

Issue

3

Start / End Page

408 / 414

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Sensitivity and Specificity
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiation Dosage
  • Practice Patterns, Physicians'
  • Nuclear Medicine & Medical Imaging
  • Multidetector Computed Tomography
  • Middle Aged
  • Male
  • Liver Transplantation
 

Citation

APA
Chicago
ICMJE
MLA
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Luke, F. E., Allen, B. C., Moshiri, S. T., Ho, L. M., Massey, C. M., Stinnett, S. S., … Jaffe, T. A. (2013). Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose? J Comput Assist Tomogr, 37(3), 408–414. https://doi.org/10.1097/RCT.0b013e3182838680
Luke, Frank E., Brian C. Allen, Sara T. Moshiri, Lisa M. Ho, Christopher M. Massey, Sandra S. Stinnett, Andrew J. Muir, and Tracy A. Jaffe. “Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose?J Comput Assist Tomogr 37, no. 3 (2013): 408–14. https://doi.org/10.1097/RCT.0b013e3182838680.
Luke, Frank E., et al. “Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose?J Comput Assist Tomogr, vol. 37, no. 3, 2013, pp. 408–14. Pubmed, doi:10.1097/RCT.0b013e3182838680.
Luke FE, Allen BC, Moshiri ST, Ho LM, Massey CM, Stinnett SS, Muir AJ, Jaffe TA. Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose? J Comput Assist Tomogr. 2013;37(3):408–414.

Published In

J Comput Assist Tomogr

DOI

EISSN

1532-3145

Publication Date

2013

Volume

37

Issue

3

Start / End Page

408 / 414

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Sensitivity and Specificity
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiation Dosage
  • Practice Patterns, Physicians'
  • Nuclear Medicine & Medical Imaging
  • Multidetector Computed Tomography
  • Middle Aged
  • Male
  • Liver Transplantation