Skip to main content
Journal cover image

Clinical utility of available methods for determining platelet function.

Publication ,  Journal Article
McKenzie, ME; Gurbel, PA; Levine, DJ; Serebruany, VL
Published in: Cardiology
1999

Determination of platelet function has become increasingly important as new antiplatelet drugs are being developed. Objective means to monitor the pharmacological effects of these agents, in order to maximize efficacy and minimize toxicity, is needed. The available methods for determination of platelet function at the current time are reviewed, including platelet aggregometry, the PFA-100, flow cytometry, platelet contractile force, the rapid platelet function assay, the clot signature analyzer, Sonoclot, and thromboelastography. The principle, advantages, disadvantages, and clinical utility of each method is presented. The uses of the various methods of determining platelet function reported in the literature are summarized, in an effort to provide information regarding the applicability of those different methods.

Duke Scholars

Published In

Cardiology

DOI

ISSN

0008-6312

Publication Date

1999

Volume

92

Issue

4

Start / End Page

240 / 247

Location

Switzerland

Related Subject Headings

  • Sensitivity and Specificity
  • Platelet Function Tests
  • Platelet Aggregation
  • Humans
  • Cardiovascular System & Hematology
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
McKenzie, M. E., Gurbel, P. A., Levine, D. J., & Serebruany, V. L. (1999). Clinical utility of available methods for determining platelet function. Cardiology, 92(4), 240–247. https://doi.org/10.1159/000006981
McKenzie, M. E., P. A. Gurbel, D. J. Levine, and V. L. Serebruany. “Clinical utility of available methods for determining platelet function.Cardiology 92, no. 4 (1999): 240–47. https://doi.org/10.1159/000006981.
McKenzie ME, Gurbel PA, Levine DJ, Serebruany VL. Clinical utility of available methods for determining platelet function. Cardiology. 1999;92(4):240–7.
McKenzie, M. E., et al. “Clinical utility of available methods for determining platelet function.Cardiology, vol. 92, no. 4, 1999, pp. 240–47. Pubmed, doi:10.1159/000006981.
McKenzie ME, Gurbel PA, Levine DJ, Serebruany VL. Clinical utility of available methods for determining platelet function. Cardiology. 1999;92(4):240–247.
Journal cover image

Published In

Cardiology

DOI

ISSN

0008-6312

Publication Date

1999

Volume

92

Issue

4

Start / End Page

240 / 247

Location

Switzerland

Related Subject Headings

  • Sensitivity and Specificity
  • Platelet Function Tests
  • Platelet Aggregation
  • Humans
  • Cardiovascular System & Hematology
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology