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Wide-field microscopy using microcamera arrays

Publication ,  Journal Article
Marks, DL; Youn, SH; Son, HS; Kim, J; Brady, DJ
Published in: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
2013

A microcamera is a relay lens paired with image sensors. Microcameras are grouped into arrays to relay overlapping views of a single large surface to the sensors to form a continuous synthetic image. The imaged surface may be curved or irregular as each camera may independently be dynamically focused to a different depth. Microcamera arrays are akin to microprocessors in supercomputers in that both join individual processors by an optoelectronic routing fabric to increase capacity and performance. A microcamera may image ten or more megapixels and grouped into an array of several hundred, as has already been demonstrated by the DARPA AWARE Wide-Field program with multiscale gigapixel photography. We adapt gigapixel microcamera array architectures to wide-field microscopy of irregularly shaped surfaces to greatly increase area imaging over 1000 square millimeters at resolutions of 3 microns or better in a single snapshot. The system includes a novel relay design, a sensor electronics package, and a FPGA-based networking fabric. Biomedical applications of this include screening for skin lesions, wide-field and resolution-agile microsurgical imaging, and microscopic cytometry of millions of cells performed in situ. © 2013 Copyright SPIE.

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Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

Publication Date

2013

Volume

8589
 

Citation

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Marks, D. L., Youn, S. H., Son, H. S., Kim, J., & Brady, D. J. (2013). Wide-field microscopy using microcamera arrays. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 8589. https://doi.org/10.1117/12.2002860
Marks, D. L., S. H. Youn, H. S. Son, J. Kim, and D. J. Brady. “Wide-field microscopy using microcamera arrays.” Progress in Biomedical Optics and Imaging - Proceedings of SPIE 8589 (2013). https://doi.org/10.1117/12.2002860.
Marks DL, Youn SH, Son HS, Kim J, Brady DJ. Wide-field microscopy using microcamera arrays. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2013;8589.
Marks, D. L., et al. “Wide-field microscopy using microcamera arrays.” Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8589, 2013. Scival, doi:10.1117/12.2002860.
Marks DL, Youn SH, Son HS, Kim J, Brady DJ. Wide-field microscopy using microcamera arrays. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2013;8589.

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

Publication Date

2013

Volume

8589