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The influence of red wine or white wine intake on platelet function and viscoelastic property of blood in volunteers.

Publication ,  Journal Article
Kikura, M; Levy, JH; Safon, RA; Lee, MK; Szlam, F
Published in: Platelets
February 2004

Since the consumption of wine in the United States has increased in recent years, a number of patients may be admitted to the hospital on the morning of their elective surgery after having consumed wine with dinner the evening before. Research indicates that by reducing platelet aggregation, moderate alcohol consumption can protect against the development of coronary artery disease. Therefore, an alcohol consumption in the night before surgery may influence on a patient's hemostasis. This study was designed to investigate the effects of wine intake the night before surgery on platelet aggregation and thromboelastogram in healthy volunteers. Twenty-four healthy subjects participated in this randomized crossover study. Each subject drank either a half bottle (300-350 ml, approximately two glasses) of red or white wine during dinner on two separate occasions. Blood samples were taken on the morning of the scheduled wine consumption and at the same time on the morning after the wine consumption. Platelet counts, and thromboelastogram (TEG) were performed and platelet function was assessed by adenosine diphosphate (ADP) and collagen induced platelet aggregation tests. There were no significant changes in platelet number, platelet function and TEG values the morning after wine consumption, and there were no significant differences in platelet number, platelet function and TEG values between red and white wine. This study indicates that an intake of red or white wine during dinner does not affect platelet number, platelet function, or viscoelastic properties of blood the next morning. A half bottle of red or white wine intake prior to a next day's elective surgery has no significant risk of suppression of coagulation function.

Duke Scholars

Published In

Platelets

DOI

ISSN

0953-7104

Publication Date

February 2004

Volume

15

Issue

1

Start / End Page

37 / 41

Location

England

Related Subject Headings

  • Wine
  • Platelet Count
  • Platelet Aggregation
  • Male
  • Humans
  • Female
  • Cross-Over Studies
  • Collagen
  • Cardiovascular System & Hematology
  • Blood Viscosity
 

Citation

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Kikura, M., Levy, J. H., Safon, R. A., Lee, M. K., & Szlam, F. (2004). The influence of red wine or white wine intake on platelet function and viscoelastic property of blood in volunteers. Platelets, 15(1), 37–41. https://doi.org/10.1080/0953710032000158772
Kikura, Mutsuhito, Jerrold H. Levy, Rebecca A. Safon, Mi K. Lee, and Fania Szlam. “The influence of red wine or white wine intake on platelet function and viscoelastic property of blood in volunteers.Platelets 15, no. 1 (February 2004): 37–41. https://doi.org/10.1080/0953710032000158772.
Kikura M, Levy JH, Safon RA, Lee MK, Szlam F. The influence of red wine or white wine intake on platelet function and viscoelastic property of blood in volunteers. Platelets. 2004 Feb;15(1):37–41.
Kikura, Mutsuhito, et al. “The influence of red wine or white wine intake on platelet function and viscoelastic property of blood in volunteers.Platelets, vol. 15, no. 1, Feb. 2004, pp. 37–41. Pubmed, doi:10.1080/0953710032000158772.
Kikura M, Levy JH, Safon RA, Lee MK, Szlam F. The influence of red wine or white wine intake on platelet function and viscoelastic property of blood in volunteers. Platelets. 2004 Feb;15(1):37–41.
Journal cover image

Published In

Platelets

DOI

ISSN

0953-7104

Publication Date

February 2004

Volume

15

Issue

1

Start / End Page

37 / 41

Location

England

Related Subject Headings

  • Wine
  • Platelet Count
  • Platelet Aggregation
  • Male
  • Humans
  • Female
  • Cross-Over Studies
  • Collagen
  • Cardiovascular System & Hematology
  • Blood Viscosity