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Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry).

Publication ,  Journal Article
Caputo, RP; Goel, A; Pencina, M; Cohen, DJ; Kleiman, NS; Yen, C-H; Waksman, R; Tolerico, P; Dhar, G; Gordon, P; Bach, RG; Lopez, JJ
Published in: Am J Cardiol
August 1, 2012

In randomized trials, longer drug-eluting stent (DES) length has been associated with adverse clinical events. We used data from the EVENT registry to examine the impact of DES length on outcomes in routine clinical practice. We identified 5,425 unselected consecutive patients from the EVENT registry who had a single vessel treated with DES for nonemergency indications from 2004 through 2007. The association between stented length and short- and long-term outcomes was analyzed in ordinal categories (<15, 15 to 19, 20 to 24, and >24 mm) and as a continuous variable. There were few differences in baseline characteristics across categories. At 1 year, there was a stepwise increase in major adverse cardiac events (composite of death, myocardial infarction [MI], and target lesion revascularization [TLR]) with increasing stent length (8.0%, 10.1%, 11.8%, and 14.8%, p <0.001) and a similar relation with TLR (3.0%, 3.1%, 3.3%, and 5.0%, p = 0.02). After adjusting for demographic, clinical, angiographic, and treatment characteristics, longer stent length remained associated with 1-year major adverse cardiac events (adjusted hazard ratio 1.17 per 10-mm increase stent length) and TLR (hazard ratio 1.20 per 10 mm), but not with stent thrombosis. In conclusion, longer DES length is associated with increased adverse events, predominantly periprocedural MI, but also an increased rate of TLR.

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Published In

Am J Cardiol

DOI

EISSN

1879-1913

Publication Date

August 1, 2012

Volume

110

Issue

3

Start / End Page

350 / 355

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Registries
  • Prosthesis Design
  • Prospective Studies
  • Middle Aged
  • Male
  • Humans
  • Female
  • Drug-Eluting Stents
  • Coronary Artery Disease
 

Citation

APA
Chicago
ICMJE
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Caputo, R. P., Goel, A., Pencina, M., Cohen, D. J., Kleiman, N. S., Yen, C.-H., … Lopez, J. J. (2012). Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry). Am J Cardiol, 110(3), 350–355. https://doi.org/10.1016/j.amjcard.2012.03.031
Caputo, Ronald P., Ankush Goel, Michael Pencina, David J. Cohen, Neal S. Kleiman, Chen-Hsing Yen, Ron Waksman, et al. “Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry).Am J Cardiol 110, no. 3 (August 1, 2012): 350–55. https://doi.org/10.1016/j.amjcard.2012.03.031.
Caputo RP, Goel A, Pencina M, Cohen DJ, Kleiman NS, Yen C-H, et al. Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry). Am J Cardiol. 2012 Aug 1;110(3):350–5.
Caputo, Ronald P., et al. “Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry).Am J Cardiol, vol. 110, no. 3, Aug. 2012, pp. 350–55. Pubmed, doi:10.1016/j.amjcard.2012.03.031.
Caputo RP, Goel A, Pencina M, Cohen DJ, Kleiman NS, Yen C-H, Waksman R, Tolerico P, Dhar G, Gordon P, Bach RG, Lopez JJ. Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry). Am J Cardiol. 2012 Aug 1;110(3):350–355.
Journal cover image

Published In

Am J Cardiol

DOI

EISSN

1879-1913

Publication Date

August 1, 2012

Volume

110

Issue

3

Start / End Page

350 / 355

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Registries
  • Prosthesis Design
  • Prospective Studies
  • Middle Aged
  • Male
  • Humans
  • Female
  • Drug-Eluting Stents
  • Coronary Artery Disease