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Estimation of radiation exposure for brain perfusion CT: standard protocol compared with deviations in protocol.

Publication ,  Journal Article
Hoang, JK; Wang, C; Frush, DP; Enterline, DS; Samei, E; Toncheva, G; Lowry, C; Yoshizumi, TT
Published in: AJR Am J Roentgenol
November 2013

OBJECTIVE: The purpose of this study was to measure the organ doses and estimate the effective dose for the standard brain perfusion CT protocol and erroneous protocols. MATERIALS AND METHODS: An anthropomorphic phantom with metal oxide semiconductor field effect transistor (MOSFET) detectors was scanned on a 64-MDCT scanner. Protocol 1 used a standard brain perfusion protocol with 80 kVp and fixed tube current of 200 mA. Protocol 2 used 120 kVp and fixed tube current of 200 mA. Protocol 3 used 120 kVp with automatic tube current modulation (noise index, 2.4; minimum, 100 mA; maximum, 520 mA). RESULTS: Compared with protocol 1, the effective dose was 2.8 times higher with protocol 2 and 7.8 times higher with protocol 3. For all protocols, the peak dose was highest in the skin, followed by the brain and calvarial marrow. Compared with protocol 1, the peak skin dose was 2.6 times higher with protocol 2 and 6.7 times higher with protocol 3. The peak skin dose for protocol 3 exceeded 3 Gy. The ocular lens received significant scatter radiation: 177 mGy for protocol 2 and 435 mGy for protocol 3, which were 4.6 and 11.3 times the dose for protocol 1, respectively. CONCLUSION: Compared with the standard protocol, erroneous protocols of increasing the tube potential from 80 kVp to 120 kVp will lead to a three- to fivefold increase in organ doses, and concurrent use of high peak kilovoltage with incorrectly programmed tube current modulation can increase dose to organs by 7- to 11-fold. Tube current modulation with a low noise index can lead to doses to the skin and ocular lens that are close to thresholds for tissue reactions.

Duke Scholars

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

November 2013

Volume

201

Issue

5

Start / End Page

W730 / W734

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiometry
  • Radiation Dosage
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Brain
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Hoang, J. K., Wang, C., Frush, D. P., Enterline, D. S., Samei, E., Toncheva, G., … Yoshizumi, T. T. (2013). Estimation of radiation exposure for brain perfusion CT: standard protocol compared with deviations in protocol. AJR Am J Roentgenol, 201(5), W730–W734. https://doi.org/10.2214/AJR.12.10031
Hoang, Jenny K., Chu Wang, Donald P. Frush, David S. Enterline, Ehsan Samei, Greta Toncheva, Carolyn Lowry, and Terry T. Yoshizumi. “Estimation of radiation exposure for brain perfusion CT: standard protocol compared with deviations in protocol.AJR Am J Roentgenol 201, no. 5 (November 2013): W730–34. https://doi.org/10.2214/AJR.12.10031.
Hoang JK, Wang C, Frush DP, Enterline DS, Samei E, Toncheva G, et al. Estimation of radiation exposure for brain perfusion CT: standard protocol compared with deviations in protocol. AJR Am J Roentgenol. 2013 Nov;201(5):W730–4.
Hoang, Jenny K., et al. “Estimation of radiation exposure for brain perfusion CT: standard protocol compared with deviations in protocol.AJR Am J Roentgenol, vol. 201, no. 5, Nov. 2013, pp. W730–34. Pubmed, doi:10.2214/AJR.12.10031.
Hoang JK, Wang C, Frush DP, Enterline DS, Samei E, Toncheva G, Lowry C, Yoshizumi TT. Estimation of radiation exposure for brain perfusion CT: standard protocol compared with deviations in protocol. AJR Am J Roentgenol. 2013 Nov;201(5):W730–W734.

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

November 2013

Volume

201

Issue

5

Start / End Page

W730 / W734

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiometry
  • Radiation Dosage
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Brain
  • 3202 Clinical sciences
  • 1103 Clinical Sciences