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Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns.

Publication ,  Journal Article
Jarvis, ED; Yu, J; Rivas, MV; Horita, H; Feenders, G; Whitney, O; Jarvis, SC; Jarvis, ER; Kubikova, L; Puck, AE; Siang-Bakshi, C; Martin, S ...
Published in: J Comp Neurol
November 2013

Based on quantitative cluster analyses of 52 constitutively expressed or behaviorally regulated genes in 23 brain regions, we present a global view of telencephalic organization of birds. The patterns of constitutively expressed genes revealed a partial mirror image organization of three major cell populations that wrap above, around, and below the ventricle and adjacent lamina through the mesopallium. The patterns of behaviorally regulated genes revealed functional columns of activation across boundaries of these cell populations, reminiscent of columns through layers of the mammalian cortex. The avian functionally regulated columns were of two types: those above the ventricle and associated mesopallial lamina, formed by our revised dorsal mesopallium, hyperpallium, and intercalated hyperpallium; and those below the ventricle, formed by our revised ventral mesopallium, nidopallium, and intercalated nidopallium. Based on these findings and known connectivity, we propose that the avian pallium has four major cell populations similar to those in mammalian cortex and some parts of the amygdala: 1) a primary sensory input population (intercalated pallium); 2) a secondary intrapallial population (nidopallium/hyperpallium); 3) a tertiary intrapallial population (mesopallium); and 4) a quaternary output population (the arcopallium). Each population contributes portions to columns that control different sensory or motor systems. We suggest that this organization of cell groups forms by expansion of contiguous developmental cell domains that wrap around the lateral ventricle and its extension through the middle of the mesopallium. We believe that the position of the lateral ventricle and its associated mesopallium lamina has resulted in a conceptual barrier to recognizing related cell groups across its border, thereby confounding our understanding of homologies with mammals. J. Comp. Neurol. 521:3614-3665, 2013. © 2013 Wiley Periodicals, Inc.

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Published In

J Comp Neurol

DOI

EISSN

1096-9861

Publication Date

November 2013

Volume

521

Issue

16

Start / End Page

Spc1

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • 1116 Medical Physiology
  • 1109 Neurosciences
  • 0608 Zoology
 

Citation

APA
Chicago
ICMJE
MLA
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Jarvis, E. D., Yu, J., Rivas, M. V., Horita, H., Feenders, G., Whitney, O., … Wada, K. (2013). Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns. J Comp Neurol, 521(16), Spc1. https://doi.org/10.1002/cne.23462
Jarvis, E. D., J. Yu, M. V. Rivas, H. Horita, G. Feenders, O. Whitney, S. C. Jarvis, et al. “Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns.J Comp Neurol 521, no. 16 (November 2013): Spc1. https://doi.org/10.1002/cne.23462.
Jarvis ED, Yu J, Rivas MV, Horita H, Feenders G, Whitney O, et al. Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns. J Comp Neurol. 2013 Nov;521(16):Spc1.
Jarvis, E. D., et al. “Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns.J Comp Neurol, vol. 521, no. 16, Nov. 2013, p. Spc1. Pubmed, doi:10.1002/cne.23462.
Jarvis ED, Yu J, Rivas MV, Horita H, Feenders G, Whitney O, Jarvis SC, Jarvis ER, Kubikova L, Puck AE, Siang-Bakshi C, Martin S, McElroy M, Hara E, Howard J, Pfenning A, Mouritsen H, Chen CC, Wada K. Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns. J Comp Neurol. 2013 Nov;521(16):Spc1.
Journal cover image

Published In

J Comp Neurol

DOI

EISSN

1096-9861

Publication Date

November 2013

Volume

521

Issue

16

Start / End Page

Spc1

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • 1116 Medical Physiology
  • 1109 Neurosciences
  • 0608 Zoology