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The Foundations of Genomic and Personalized Medicine

Publication ,  Journal Article
Ginsburg, GS; Willard, HF
December 1, 2010

This chapter presents the principles and applications underlying genomic and personalized medicine. Genomics is the scientific study of a genome or genomes. A genome is the complete DNA sequence containing the entire genetic information of a gamete, an individual, a population, or a species. Personalized medicine refers to a rapidly advancing field of health care that is informed by each person's unique clinical, genetic, genomic, and environmental information. Personalized medicine aims to take advantage of the molecular understanding of disease. This is done to optimize preventive health care strategies and drug therapies while people are still well or at the earliest stages of disease. These factors are different for every person. Therefore the nature of disease, its onset, its course, and its response to drug or other interventions are as individual as the people who have them. In order for personalized medicine to be used by health care providers and their patients, the findings must be translated into precision diagnostic tests and targeted therapies. Since the overarching goal is to optimize medical care and outcomes for each individual, treatments, medication types and dosages, and/or prevention strategies may differ from person to person, resulting in unprecedented customization of patient care. © 2010 Copyright © 2010 Elsevier Inc. All rights reserved.

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December 1, 2010

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Ginsburg, G. S., & Willard, H. F. (2010). The Foundations of Genomic and Personalized Medicine, 1–10. https://doi.org/10.1016/B978-0-12-374934-5.00001-5
Ginsburg, G. S., and H. F. Willard. “The Foundations of Genomic and Personalized Medicine,” December 1, 2010, 1–10. https://doi.org/10.1016/B978-0-12-374934-5.00001-5.
Ginsburg GS, Willard HF. The Foundations of Genomic and Personalized Medicine. 2010 Dec 1;1–10.
Ginsburg, G. S., and H. F. Willard. The Foundations of Genomic and Personalized Medicine. Dec. 2010, pp. 1–10. Scopus, doi:10.1016/B978-0-12-374934-5.00001-5.
Ginsburg GS, Willard HF. The Foundations of Genomic and Personalized Medicine. 2010 Dec 1;1–10.

DOI

Publication Date

December 1, 2010

Start / End Page

1 / 10