Skip to main content
Journal cover image

Surface-enhanced Raman scattering plasmonic enhancement using DNA origami-based complex metallic nanostructures.

Publication ,  Journal Article
Pilo-Pais, M; Watson, A; Demers, S; LaBean, TH; Finkelstein, G
Published in: Nano letters
January 2014

DNA origami is a novel self-assembly technique allowing one to form various two-dimensional shapes and position matter with nanometer accuracy. We use DNA origami templates to engineer surface-enhanced Raman scattering substrates. Specifically, gold nanoparticles were selectively placed on the corners of rectangular origami and subsequently enlarged via solution-based metal deposition. The resulting assemblies exhibit "hot spots" of enhanced electromagnetic field between the nanoparticles. We observed a significant Raman signal enhancement from molecules covalently attached to the assemblies, as compared to control nanoparticle samples that lack interparticle hot spots. Furthermore, Raman molecules are used to map out the hot spots' distribution, as they are burned when experiencing a threshold electric field. Our method opens up the prospects of using DNA origami to rationally engineer and assemble plasmonic structures for molecular spectroscopy.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Nano letters

DOI

EISSN

1530-6992

ISSN

1530-6984

Publication Date

January 2014

Volume

14

Issue

4

Start / End Page

2099 / 2104

Related Subject Headings

  • Surface Properties
  • Sulfanilic Acids
  • Spectrum Analysis, Raman
  • Nucleic Acid Conformation
  • Nanostructures
  • Nanoscience & Nanotechnology
  • Metal Nanoparticles
  • Gold
  • Dimerization
  • DNA
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Pilo-Pais, M., Watson, A., Demers, S., LaBean, T. H., & Finkelstein, G. (2014). Surface-enhanced Raman scattering plasmonic enhancement using DNA origami-based complex metallic nanostructures. Nano Letters, 14(4), 2099–2104. https://doi.org/10.1021/nl5003069
Pilo-Pais, M., A. Watson, S. Demers, T. H. LaBean, and G. Finkelstein. “Surface-enhanced Raman scattering plasmonic enhancement using DNA origami-based complex metallic nanostructures.Nano Letters 14, no. 4 (January 2014): 2099–2104. https://doi.org/10.1021/nl5003069.
Pilo-Pais M, Watson A, Demers S, LaBean TH, Finkelstein G. Surface-enhanced Raman scattering plasmonic enhancement using DNA origami-based complex metallic nanostructures. Nano letters. 2014 Jan;14(4):2099–104.
Pilo-Pais, M., et al. “Surface-enhanced Raman scattering plasmonic enhancement using DNA origami-based complex metallic nanostructures.Nano Letters, vol. 14, no. 4, Jan. 2014, pp. 2099–104. Epmc, doi:10.1021/nl5003069.
Pilo-Pais M, Watson A, Demers S, LaBean TH, Finkelstein G. Surface-enhanced Raman scattering plasmonic enhancement using DNA origami-based complex metallic nanostructures. Nano letters. 2014 Jan;14(4):2099–2104.
Journal cover image

Published In

Nano letters

DOI

EISSN

1530-6992

ISSN

1530-6984

Publication Date

January 2014

Volume

14

Issue

4

Start / End Page

2099 / 2104

Related Subject Headings

  • Surface Properties
  • Sulfanilic Acids
  • Spectrum Analysis, Raman
  • Nucleic Acid Conformation
  • Nanostructures
  • Nanoscience & Nanotechnology
  • Metal Nanoparticles
  • Gold
  • Dimerization
  • DNA