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Clear cell chondrosarcoma: Cytologic findings in six cases.

Publication ,  Journal Article
Jiang, XS; Pantanowitz, L; Bui, MM; Esther, R; Budwit, D; Dodd, LG
Published in: Diagn Cytopathol
September 2014

Clear cell chondrosarcoma (CCCS) is a rare variant of chondrosarcoma characterized, in most instances, by indolent behavior and a long interval to progression of disease. CCCS commonly occurs in adult individuals and has a proclivity for the epiphysis of long bones, although it has been reported in other sites. This lesion is difficult to diagnose preoperatively. Factors contributing to difficulty in recognizing this lesion include its relative scarcity as well as its tendency to be confused with other lesions on imaging studies. In the following, we report six cases of CCCS initially diagnosed by fine needle aspiration and/or touch preparations of needle biopsy samples. The cytologic features identified include large, plasmacytoid cells with foamy cytoplasm as well as extracellular chondroid type matrix material. Definitive diagnosis was made in each case by recognizing the "clear cell" nature of the tumor on cell block material.

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Published In

Diagn Cytopathol

DOI

EISSN

1097-0339

Publication Date

September 2014

Volume

42

Issue

9

Start / End Page

784 / 791

Location

United States

Related Subject Headings

  • Spinal Neoplasms
  • Sarcoma, Clear Cell
  • Radiography
  • Pathology
  • Middle Aged
  • Male
  • Humans
  • Diagnosis, Differential
  • Chondrosarcoma
  • Biopsy, Fine-Needle
 

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Jiang, X. S., Pantanowitz, L., Bui, M. M., Esther, R., Budwit, D., & Dodd, L. G. (2014). Clear cell chondrosarcoma: Cytologic findings in six cases. Diagn Cytopathol, 42(9), 784–791. https://doi.org/10.1002/dc.23043
Jiang, Xiaoyin Sara, Liron Pantanowitz, Marilyn M. Bui, Robert Esther, Debra Budwit, and Leslie G. Dodd. “Clear cell chondrosarcoma: Cytologic findings in six cases.Diagn Cytopathol 42, no. 9 (September 2014): 784–91. https://doi.org/10.1002/dc.23043.
Jiang XS, Pantanowitz L, Bui MM, Esther R, Budwit D, Dodd LG. Clear cell chondrosarcoma: Cytologic findings in six cases. Diagn Cytopathol. 2014 Sep;42(9):784–91.
Jiang, Xiaoyin Sara, et al. “Clear cell chondrosarcoma: Cytologic findings in six cases.Diagn Cytopathol, vol. 42, no. 9, Sept. 2014, pp. 784–91. Pubmed, doi:10.1002/dc.23043.
Jiang XS, Pantanowitz L, Bui MM, Esther R, Budwit D, Dodd LG. Clear cell chondrosarcoma: Cytologic findings in six cases. Diagn Cytopathol. 2014 Sep;42(9):784–791.
Journal cover image

Published In

Diagn Cytopathol

DOI

EISSN

1097-0339

Publication Date

September 2014

Volume

42

Issue

9

Start / End Page

784 / 791

Location

United States

Related Subject Headings

  • Spinal Neoplasms
  • Sarcoma, Clear Cell
  • Radiography
  • Pathology
  • Middle Aged
  • Male
  • Humans
  • Diagnosis, Differential
  • Chondrosarcoma
  • Biopsy, Fine-Needle