The role of platelet function testing in risk stratification and clinical decision-making
Publication
, Journal Article
Gurbel, PA; Tantry, US
Published in: Interventional Cardiology Clinics
October 1, 2013
Clopidogrel (a widely used second-generation thienopyridine) therapy is associated with an unpredictable pharmacodynamic response whereby approximately 1 in 3 patients will have a high on-treatment platelet reactivity to adenosine diphosphate. High on-treatment platelet reactivity is an established risk factor for ischemic event occurrence in patients undergoing percutaneous coronary intervention. Platelet function testing may have a role in monitoring therapeutic efficacy when clopidogrel is the chosen agent and in safety when more potent drugs are used, especially in patients with high bleeding risk. At this time, it seems most reasonable to assess platelet function in high-risk clopidogrel-treated patients. © 2013 Elsevier Inc.
Duke Scholars
Published In
Interventional Cardiology Clinics
DOI
ISSN
2211-7458
Publication Date
October 1, 2013
Volume
2
Issue
4
Start / End Page
607 / 614
Citation
APA
Chicago
ICMJE
MLA
NLM
Gurbel, P. A., & Tantry, U. S. (2013). The role of platelet function testing in risk stratification and clinical decision-making. Interventional Cardiology Clinics, 2(4), 607–614. https://doi.org/10.1016/j.iccl.2013.05.009
Gurbel, P. A., and U. S. Tantry. “The role of platelet function testing in risk stratification and clinical decision-making.” Interventional Cardiology Clinics 2, no. 4 (October 1, 2013): 607–14. https://doi.org/10.1016/j.iccl.2013.05.009.
Gurbel PA, Tantry US. The role of platelet function testing in risk stratification and clinical decision-making. Interventional Cardiology Clinics. 2013 Oct 1;2(4):607–14.
Gurbel, P. A., and U. S. Tantry. “The role of platelet function testing in risk stratification and clinical decision-making.” Interventional Cardiology Clinics, vol. 2, no. 4, Oct. 2013, pp. 607–14. Scopus, doi:10.1016/j.iccl.2013.05.009.
Gurbel PA, Tantry US. The role of platelet function testing in risk stratification and clinical decision-making. Interventional Cardiology Clinics. 2013 Oct 1;2(4):607–614.
Published In
Interventional Cardiology Clinics
DOI
ISSN
2211-7458
Publication Date
October 1, 2013
Volume
2
Issue
4
Start / End Page
607 / 614