Immunology

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  Subject Areas on Research

  • "Cannibalistic" phagocytosis in acute megakaryoblastic leukemia (AML M7) with t(10;17)(p15;q22). 
  • 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. 
  • 125-P: Long-term outcome of lung recipients sensitized to HLA (Ab+recips) receiving desensitization (DS) therapy 
  • 14-3-3 zeta protein secreted by tumor associated monocytes/macrophages from ascites of epithelial ovarian cancer patients. 
  • 14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends 
  • 14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends. 
  • 14th International Congress on Antiphospholipid Antibodies: task force report on antiphospholipid syndrome treatment trends. 
  • 173: Outcomes of matched related donor bone marrow transplantation in pediatric patients with myelodysplastic syndrome 
  • 2,4-Dienoyl-coenzyme A reductase deficiency: a possible new disorder of fatty acid oxidation. 
  • 224: Outcomes of Unrelated Umbilical Cord Blood Transplantation in Pediatric Patients with Myelodysplastic Syndrome 
  • 2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis. 
  • 4-hydroperoxycyclophosphamide--purged peripheral blood stem cells for autologous transplantation in patients with acute myeloid leukemia. 
  • 5-Oxo-eicosatetraenoate is a broadly active, eosinophil-selective stimulus for human granulocytes. 
  • 63: Outcomes of Unrelated Umbilical Cord Blood Transplantation in 159 Young Patients with Peroxisomal and Lysosomal Storage Disorders at a Single Center 
  • A 10 Day Schedule of Azacitidine Induces More Complete Cytogenetic Remissions Than the Standard Schedule In Myelodysplasia and Acute Myeloid Leukemia with Myelodysplasia-Related Changes: Results of the E1905 US Leukemia Intergroup Study 
  • A CD91-positive subset of CD11c+ blood dendritic cells: characterization of the APC that functions to enhance adaptive immune responses against CD91-targeted antigens. 
  • A Cancer and Leukemia Group B multi-center study of DA-EPOCH-rituximab in untreated diffuse large B-cell lymphoma with analysis of outcome by molecular subtype. 
  • A Couple-Based Communication Intervention for Hematopoietic Cell Transplantation Survivors and Their Caregiving Partners: Feasibility, Acceptability, and Change in Process Measures. 
  • A Multi-Vector, Multi-Envelope HIV-1 Vaccine. 
  • A Multicenter Retrospective Analysis Stressing the Importance of Long-Term Follow-Up after Hematopoietic Cell Transplantation for β-Thalassemia. 
  • A National Survey Study of Transplant Physicians' Attitudes About Palliative Care 
  • A North American multilaboratory study of CD4 counts using flow cytometric panLeukogating (PLG): a NIAID-DAIDS Immunology Quality Assessment Program Study. 
  • A Pathobiological Role of the Insulin Receptor in Chronic Lymphocytic Leukemia 
  • A Phase 1 Trial of Inotuzumab in Combination with CVP (Cyclophosphamide, Vincristine, Prednisone) for Relapsed/ Refractory CD22+Acute Leukemia (SWOG 1312) 
  • A Phase 1 Trial of SGN-CD33A As Monotherapy in Patients with CD33-Positive Acute Myeloid Leukemia (AML) 
  • A Phase 1/2 Study of G-CSF, Cladribine, Cytarabine, and Dose-Escalated Mitoxantrone (G-CLAM) in Adults with Newly Diagnosed Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) 
  • A Phase 1b Study of Vadastuximab Talirine As Maintenance and in Combination with Standard Consolidation for Patients with Acute Myeloid Leukemia (AML) 
  • A Phase 1b Study of Vadastuximab Talirine in Combination with 7+3 Induction Therapy for Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) 
  • A Phase II Trial of Azacitidine (NSC-102816) and Gemtuzumab Ozogamicin (NSC-720568) As Induction and Post-Remission Therapy in Patients of Age 60 and Older with Previously Untreated Non-M3 Acute Myeloid Leukemia (SWOG S0703): Report On the Poor Risk Patients 
  • A Phase II study of Bcl-2 antisense (oblimersen sodium) combined with gemtuzumab ozogamicin in older patients with acute myeloid leukemia in first relapse. 
  • A Prospective Randomized Double Blind Phase 3 Clinical Trial of Anti- T Lymphocyte Globulin (ATLG) to Assess Impact on Chronic Graft-Versus-Host Disease (cGVHD) Free Survival in Patients Undergoing HLA Matched Unrelated Myeloablative Hematopoietic Cell Transplantation (HCT) 
  • A Prospective Study of Reduced Intensity Conditioning (RIC) in Children Undergoing Unrelated Umbilical Cord Blood Transplantation (UCBT) for Non-Malignant Diseases: Preliminary Results Demonstrate a High Rate of Engraftment and Low Incidence of GVHD 
  • A RIPK3–Caspase 8 Complex Mediates Atypical Pro–IL-1β Processing 
  • A Randomized Phase II Study of Azacitidine Combined with Lenalidomide or with Vorinostat Vs. Azacitidine Monotherapy in Higher-Risk Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML): North American Intergroup Study SWOG S1117 
  • A Retrospective Multi-Center Analysis of Prognostic Factors Determining Outcomes In Patients with Secondary AML. 
  • A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection. 
  • A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome. 
  • A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. 
  • A birthday for B cells: Lymphopoiesis II, a scientific symposium honoring Max Cooper. 
  • A c-Myc and surface CD19 signaling amplification loop promotes B cell lymphoma development and progression in mice. 
  • A case series describing causes of death in pregnant women with sickle cell disease in a low-resource setting. 
  • A cell-based model of coagulation and the role of factor VIIa. 
  • A combination of 5-fluorouracil and membrane-bound antibody inhibits B-cell lymphoma growth in a mouse model system. 
  • A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer. 
  • A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients. 
  • A comparative study of the generation of dendritic cells from mobilized peripheral blood progenitor cells of patients undergoing high-dose chemotherapy. 
  • A computational framework for the analysis of peptide microarray antibody binding data with application to HIV vaccine profiling. 
  • A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection. 
  • A critical role for the autophagy gene Atg5 in T cell survival and proliferation. 
  • A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension. 
  • A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes 
  • A cytokine cocktail directly modulates the phenotype of DC-enriched anti-tumor T cells to convey potent anti-tumor activities in a murine model. 
  • A cytokine-based neuroimmunologic mechanism of cancer-related symptoms. 
  • A cytotoxic proteinase isolated from human lymphocytes. 
  • A descriptive study of the variation in baseline levels of antiendotoxin core antibodies between US and UK populations. 
  • A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires. 
  • A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells. 
  • A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia. 
  • A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: Cancer and leukemia group B study 8811 
  • A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: cancer and leukemia group B study 8811. 
  • A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros. 
  • A functional role for circulating mouse L-selectin in regulating leukocyte/endothelial cell interactions in vivo. 
  • A futile metabolic cycle activated in adipocytes by antidiabetic agents. 
  • A genetic investigation of E2A function in lymphocyte development. 
  • A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo. 
  • A guanine nucleotide regulatory protein controls polyphosphoinositide metabolism, Ca2+ mobilization, and cellular responses to chemoattractants in human monocytes. 
  • A guide to immunometabolism for immunologists. 
  • A high endothelial cell-derived chemokine induces rapid, efficient, and subset-selective arrest of rolling T lymphocytes on a reconstituted endothelial substrate. 
  • A human anti-HIV autoantibody enhances EBV transformation and HIV infection. 
  • A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. 
  • A human novel gene DERPC on 16q22.1 inhibits prostate tumor cell growth and its expression is decreased in prostate and renal tumors. 
  • A human-human hybridoma secreting anti-HLA class II antibody. 
  • A large sample of finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter. 
  • A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection. 
  • A model for harmonizing flow cytometry in clinical trials. 
  • A multicenter pilot evaluation of the National Institutes of Health chronic graft-versus-host disease (cGVHD) therapeutic response measures: feasibility, interrater reliability, and minimum detectable change. 
  • A multicenter, phase II study of maintenance azacitidine in older patients with acute myeloid leukemia in complete remission after induction chemotherapy. 
  • A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities. 
  • A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. 
  • A neutrophil chemotatic factor derived from C'5 upon interaction of guinea pig serum with endotoxin. 
  • A new cardiac MASTer switch for the renin-angiotensin system. 
  • A new entry route for HIV. 
  • A new genetic model for separating and analyzing Treg cells in unchallenged mice based on their proliferative history 
  • A new twist to the leukocyte adhesion cascade: intimate cooperation is key. 
  • A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer. 
  • A noncanonical function of cGAMP in inflammasome priming and activation. 
  • A noncanonical role for the CKI-RB-E2F cell-cycle signaling pathway in plant effector-triggered immunity. 
  • A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily. 
  • A novel neurotoxoid vaccine prevents mucosal botulism. 
  • A novel protective effect of erythropoietin in the infarcted heart. 
  • A novel reduced-intensity conditioning regimen for unrelated umbilical cord blood transplantation in children with nonmalignant diseases 
  • A novel triple purge strategy for eliminating chronic myelogenous leukemia (CML) cells from autografts. 
  • A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays. 
  • A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. 
  • A phase 1 trial of vadastuximab talirine as monotherapy in patients with CD33-positive acute myeloid leukemia. 
  • A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML. 
  • A phase 1/2 study of an adjuvanted varicella-zoster virus subunit vaccine in autologous hematopoietic cell transplant recipients. 
  • A phase 2 study of mocetinostat, a histone deacetylase inhibitor, in relapsed or refractory lymphoma. 
  • A phase 2 trial of azacitidine and gemtuzumab ozogamicin therapy in older patients with acute myeloid leukemia. 
  • A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia. 
  • A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer. 
  • A phase I trial of recombinant human interleukin-1 beta (OCT-43) following high-dose chemotherapy and autologous bone marrow transplantation. 
  • A phase I trial of recombinant human interleukin-1 beta alone and in combination with myelosuppressive doses of 5-fluorouracil in patients with gastrointestinal cancer. 
  • A phase I/II study of CY and topotecan in patients with high-risk malignancies undergoing autologous hematopoietic cell transplantation: the St Jude long-term follow-up. 
  • A phase II study of elacytarabine in combination with idarubicin and of human equilibrative nucleoside transporter 1 expression in patients with acute myeloid leukemia and persistent blasts after the first induction course. 
  • A phase II trial of combination therapy with arsenic trioxide (ATO) and gemtuzumab ozogamicin (GO) in patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) arising from MDS. 
  • A phase II/III randomized, multicenter trial of prednisone/sirolimus versus prednisone/ sirolimus/calcineurin inhibitor for the treatment of chronic graft-versus-host disease: BMT CTN 0801. 
  • A phase III trial of high-dose cytosine arabinoside with or without etoposide in relapsed and refractory acute myelogenous leukemia. A Southeastern Cancer Study Group trial. 
  • A preliminary study of a health related quality of life assessment of priority symptoms in advanced lymphoma: the National Comprehensive Cancer Network-Functional Assessment of Cancer Therapy - Lymphoma Symptom Index. 
  • A promoter polymorphism in the gene encoding interleukin-12 p40 (IL12B) is associated with mortality from cerebral malaria and with reduced nitric oxide production. 
  • A prospective randomized trial of buffy coat versus CD34-selected autologous bone marrow support in high-risk breast cancer patients receiving high-dose chemotherapy. 
  • A randomized comparison between rasburicase and allopurinol in children with lymphoma or leukemia at high risk for tumor lysis. 
  • A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia. 
  • A randomized controlled trial comparing two vaso-occlusive episode (VOE) protocols in sickle cell disease (SCD). 
  • A randomized controlled trial of filgrastim during remission induction and consolidation chemotherapy for adults with acute lymphoblastic leukemia: CALGB study 9111. 
  • A randomized phase II study of standard-dose versus high-dose rituximab with BEAM in autologous stem cell transplantation for relapsed aggressive B-cell non-hodgkin lymphomas: long term results. 
  • A randomized phase II trial of fludarabine/melphalan 100 versus fludarabine/melphalan 140 followed by allogeneic hematopoietic stem cell transplantation for patients with multiple myeloma. 
  • A randomized trial of amifostine and carmustine-containing chemotherapy to assess lung-protective effects. 
  • A randomized trial of recombinant human interleukin-11 following autologous bone marrow transplantation with peripheral blood progenitor cell support in patients with breast cancer. 
  • A randomized, open-label study of Lestaurtinib (CEP-701), an oral FLT3 inhibitor, administered in sequence with chemotherapy in patients with relapsed AML harboring FLT3 activating mutations: Clinical response correlates with successful FLT3 inhibition. 
  • A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents. 
  • A receptor for the third component of complement in the human renal glomerulus. 
  • A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. 
  • A retrospective analysis of therapy for acute graft-versus-host disease: initial treatment. 
  • A risk factor analysis of outcomes after unrelated cord blood transplantation for children with Wiskott-Aldrich syndrome. 
  • A role for MAPK in feedback inhibition of Tcrb recombination. 
  • A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes. 
  • A role for the cytoplasmic tail of the β chain of CD8 in thymic selection 
  • A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection 
  • A simple and enzyme-free method for processing infiltrating lymphocytes from small mouse tumors for ELISpot analysis. 
  • A single amino acid defines cross-species reactivity of tree shrew (Tupaia belangeri) CD1d to human invariant natural killer T (iNKT) cells. 
  • A single cell analysis of immunoglobulin genes in chronic lymphocytic leukemia (CLL): Progressive somatic mutations in the immunoglobulin heavy and light chains contribute to intraclonal diversification in CLL. 
  • A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells. 
  • A spatially and temporally restricted mouse model of soft tissue sarcoma. 
  • A study of filgrastim (rG-CSF) priming of etoposide/cisplatin in advanced non-small cell lung cancer. 
  • A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-gamma treatment. 
  • A survival guide to early T cell development. 
  • A survivor of breast cancer with immunity to MUC-1 mucin, and lactational mastitis. 
  • A synthetic peptide homologous to retroviral envelope protein down-regulates TNF-alpha and IFN-gamma mRNA expression. 
  • A synthetic peptide homologous to the envelope proteins of retroviruses inhibits monocyte-mediated killing by inactivating interleukin 1. 
  • A tale of two callings. 
  • A threshold for central T cell tolerance to an inducible serum protein. 
  • A tribute to Michael S. Neuberger. 
  • A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. 
  • AAP Presidential Address: The AAP and the transformation of medicine. 
  • ADA Deficiency: Evaluation of the Clinical and Laboratory Features and the Outcome 
  • ADAM10 is essential for proteolytic activation of Notch during thymocyte development. 
  • ADA酵素蛋白の安定性を相乗的に阻害する"WAZA-ARI"変異を認めたADA欠損症の1例 
  • ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. 
  • AI for medical imaging goes deep. 
  • AIF Is "Always In Fashion" for T Cells. 
  • ALK-negative anaplastic large cell lymphoma is a genetically heterogeneous disease with widely disparate clinical outcomes. 
  • ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. 
  • AML-loaded DC generate Th1-type cellular immune responses in vitro. 
  • ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling. 
  • ASBMT committee report: white paper on measurement of quality outcomes. 
  • ASBMT policy statement regarding the methodology of evidence-based reviews in evaluating the role of blood and marrow transplantation in the treatment of selected diseases. American Society for Blood and Marrow Transplantation. 
  • ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category. 
  • ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes. 
  • Aberrant B-cell homeostasis in chronic GVHD. 
  • Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma. 
  • Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology. 
  • Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages. 
  • Abl tyrosine kinases in T-cell signaling. 
  • Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule. 
  • Abnormal parathyroid hormone stimulation of 25-hydroxyvitamin D-1 alpha-hydroxylase activity in the hypophosphatemic mouse. Evidence for a generalized defect of vitamin D metabolism. 
  • Abnormal regulation of renal 25-hydroxyvitamin D-1 alpha-hydroxylase activity in the X-linked hypophosphatemic mouse. 
  • Abnormalities in the regulation of human IgE synthesis. 
  • Absence of immunodominant anti-Gag p17 (SL9) responses among Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele. 
  • Absolute values of dendritic cell subsets in bone marrow, cord blood, and peripheral blood enumerated by a novel method. 
  • Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens. 
  • Acquired hypoprothrombinemia: effects of danazol treatment. 
  • Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors. 
  • Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma. 
  • Activated protein C cleaves factor Va more efficiently on endothelium than on platelet surfaces. 
  • Activation of human B cells by phosphorothioate oligodeoxynucleotides. 
  • Activation of the guinea pig granulocyte NAD(P)H-dependent superoxide generating enzyme: localization in a plasma membrane enriched particle and kinetics of activation. 
  • Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor. 
  • Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms. 
  • Acute and chronic phagocyte determinants of cardiac allograft vasculopathy 
  • Acute graft-versus-host disease: analysis of risk factors after allogeneic marrow transplantation and prophylaxis with cyclosporine and methotrexate. 
  • Acute graft-vs-host disease: pathobiology and management. 
  • Acute myeloid leukemia ontogeny is defined by distinct somatic mutations. 
  • Acute pancreatitis during immunosuppression with tacrolimus following an allogeneic umbilical cord blood transplantation. 
  • Adaptations of Innate Immunity in Hibernation: Mechanisms for Protection Against Acute Organ Injury 
  • Additional Analyses of a Randomized Phase II Study of Azacitidine Combined with Lenalidomide or with Vorinostat Vs. Azacitidine Monotherapy in Higher-Risk Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML): North American Intergroup Study SWOG S1117 
  • Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements. 
  • Adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency in common variable immunodeficiency. 
  • Adenosine deaminase deficiency in adults. 
  • Adenovirus F protein as a delivery vehicle for botulinum B. 
  • Adhesion molecules and hydroxyurea in the pathophysiology of sickle cell disease. 
  • Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy. 
  • Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition. 
  • Administration of a CD31-derived peptide delays the onset and significantly increases survival from lethal graft-versus-host disease. 
  • Adoptive immunotherapy by allogeneic stem cell transplantation for metastatic renal cell carcinoma: a CALGB intergroup phase II study. 
  • Adrenal cortical regulation of the distribution of water and electrolytes in the human body. 
  • Adult Umbilical Cord Blood Transplantation Using Myeloablative Thiotepa, Total Body Irradiation, and Fludarabine Conditioning. 
  • Adult Umbilical Cord Blood Transplantation Using Myeloablative Total Body Irradiation, Fludarabine, and Thiotepa Conditioning 
  • Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets. 
  • Adult patients with de novo acute myeloid leukemia and t(9; 11)(p22; q23) have a superior outcome to patients with other translocations involving band 11q23: a cancer and leukemia group B study. 
  • Adventures within the speckled band: heterogeneity, angiogenesis, and balanced inflammation in the tuberculous granuloma. 
  • Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. 
  • African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity. 
  • Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury. 
  • Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates. 
  • Alemtuzumab for the prevention and treatment of graft-versus-host disease. 
  • All-Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients 
  • Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis. 
  • Allelic exclusion of mouse T cell receptor alpha chains occurs at the time of thymocyte TCR up-regulation. 
  • Allogeneic Hematopoietic Cell Transplantation for Aggressive NK Cell Leukemia. A Center for International Blood and Marrow Transplant Research Analysis. 
  • Allogeneic Hematopoietic Stem Cell Transplantation with Clofarabine/Busulfan x 4 (CloBu4) Conditioning Exhibits Significant Anti-Tumor Activity In Non - Remission Hematologic Malignancies, Especially In AML 
  • Allogeneic Umbilical Cord Blood Infusion for Adults with Ischemic Stroke (CoBIS): Clinical Outcomes from a Phase 1 Safety Study 
  • Allogeneic bone marrow transplantation for high-risk acute lymphoblastic leukemia during first complete remission. 
  • Allogeneic haematopoietic cell transplantation with clofarabine/busulfan x 4 conditioning exhibits significant anti-leukaemic activity in non-remission AML 
  • Allogeneic hematopoietic cell transplantation for chemotherapy-unresponsive mantle cell lymphoma: a cohort analysis from the center for international blood and marrow transplant research. 
  • Allogeneic human mesenchymal stem cell therapy (remestemcel-L, Prochymal) as a rescue agent for severe refractory acute graft-versus-host disease in pediatric patients. 
  • Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens. 
  • Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: a randomized trial of two irradiation regimens. 
  • Allogeneic stem cell transplantation for patients with chronic myeloid leukemia and acute lymphocytic leukemia after Bcr-Abl kinase mutation-related imatinib failure. 
  • Alteration Of Cytogenetic Risk Stratification In New Diagnosis Of Leukemia By FISH Testing - Retrospective Review Of The SWOG Experience 
  • Alterations in antibody-dependent cellular cytotoxicity during the course of HIV-1 infection. Humoral and cellular defects. 
  • Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy. 
  • Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome. 
  • Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. 
  • Altered cell-averaged microviscosity of murine peritoneal macrophages undergoing activation in vivo or in vitro. 
  • Altered gene expression in busulfan-resistant human myeloid leukemia. 
  • Aluminum deposition at the osteoid-bone interface. An epiphenomenon of the osteomalacic state in vitamin D-deficient dogs. 
  • Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression. 
  • Alzheimer’s disease: the new promise. 
  • Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer. 
  • Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors 
  • American Society of Hematology/American Society of Clinical Oncology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer. 
  • Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support. 
  • Amino acid substitution at peptide-binding pockets of HLA class I molecules increases risk of severe acute GVHD and mortality. 
  • Amiodarone and cyclophosphamide: potential for enhanced lung toxicity. 
  • Amplification of suppressor inducer pathway with monoclonal antibody, anti-2H4, identifying a novel epitope of the common leukocyte antigen/T200 antigen. 
  • An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells. 
  • An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease. 
  • An Ectopic CTCF Binding Element Inhibits Tcrd Rearrangement by Limiting Contact between Vδ and Dδ Gene Segments. 
  • An HIV Envelope gp120-Fc Fusion Protein Elicits Effector Antibody Responses in Rhesus Macaques. 
  • An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD. 
  • An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer. 
  • An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus. 
  • An analysis of clinical and laboratory features of acute lymphocytic leukemias with emphasis on 35 children with pre-B leukemia. 
  • An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. 
  • An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. 
  • An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis. 
  • An essential role for c-FLIP in the efficient development of mature T lymphocytes. 
  • An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system. 
  • An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. 
  • Anabolic effects of a G protein-coupled receptor kinase inhibitor expressed in osteoblasts. 
  • Analysis of a Global Registration Trial of the Efficacy and Safety of CTL019 in Pediatric and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) 
  • Analysis of autoantibodies to plasminogen in the serum of patients with rheumatoid arthritis. 
  • Analysis of autoantibody binding to different regions of the human La antigen expressed in recombinant fusion proteins. 
  • Analysis of clones derived from human CD7+CD4-CD8-CD3- thymocytes. 
  • Analysis of expression of CD2, CD3, and T cell antigen receptor molecules during early human fetal thymic development. 
  • Analysis of regulatory CD8 T cells in Qa-1-deficient mice. 
  • Analysis of risk factors influencing outcomes after cord blood transplantation in children with juvenile myelomonocytic leukemia: a EUROCORD, EBMT, EWOG-MDS, CIBMTR study. 
  • Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection. 
  • Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases. 
  • Analysis of the cellular components of the graft and clinical characteristics of 159 children with lysosomal and peroxisomal disorders (LSD) undergoing unrelated umbilical cord blood transplantation at a single center 
  • Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancer. 
  • Androgen regulation of rat renal angiotensinogen messenger RNA expression. 
  • Anemia of inflammation: the cytokine-hepcidin link. 
  • Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. 
  • Angiopoietin-1 is required for Schlemm's canal development in mice and humans. 
  • Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. 
  • Angiotensin II stimulates canonical TGF-β signaling pathway through angiotensin type 1 receptor to induce granulation tissue contraction 
  • Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression. 
  • Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic β cell insufficiency. 
  • Anti-CD22 ligand-blocking antibody HB22.7 has independent lymphomacidal properties and augments the efficacy of 90Y-DOTA-peptide-Lym-1 in lymphoma xenografts. 
  • Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis. 
  • Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. 
  • Anti-La antibody production by MRL-1pr/1pr mice. Analysis of fine specificity. 
  • Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation. 
  • Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation. 
  • Anti-tumor activity of a novel monoclonal antibody, NPC-1C, optimized for recognition of tumor antigen MUC5AC variant in preclinical models. 
  • Anti-tumor immunotherapy despite immunity to adenovirus using a novel adenoviral vector Ad5 [E1-, E2b-]-CEA. 
  • Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation. 
  • Antibodies to granulocyte precursors in selective myeloid hypoplasia and other suspected autoimmune neutropenias: use of HL-60 cells as targets. 
  • Antibodies to stem cell marker antigens reduce engraftment of hematopoietic stem cells. 
  • Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy. 
  • Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved. 
  • Antibody polyspecificity and neutralization of HIV-1: a hypothesis. 
  • Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis. 
  • Antibody responses to bacteriophage phi X174 in patients with adenosine deaminase deficiency. 
  • Antibody to VLA-4, but not to L-selectin, protects neuronal M2 muscarinic receptors in antigen-challenged guinea pig airways. 
  • Antibody to native human immunodeficiency virus type 1 envelope glycoproteins induced by IIIB and MN recombinant gp120 vaccines. The NIAID AIDS Vaccine Evaluation Group. 
  • Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia. 
  • Antibody-induced proteinase activation: a proposed mechanism for pemphigus. 
  • Antibody-induced release of cellular proteinases: loss of adhesion of human melanoma cells after binding of anti-melanoma antibody. 
  • Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice. 
  • Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin). 
  • Antibody-virus co-evolution in HIV infection: paths for HIV vaccine development. 
  • Antigen-presenting cells pulsed with unfractionated tumor-derived peptides are potent tumor vaccines. 
  • Antigen-specific T-lymphocyte function after cord blood transplantation. 
  • Antiinflammatory effects of neoplasms. 
  • Antileukemic Activity and Tolerability of ASP2215 80mg and Greater in FLT3 Mutation-Positive Subjects with Relapsed or Refractory Acute Myeloid Leukemia: Results from a Phase 1/2, Open-Label, Dose-Escalation/Dose-Response Study 
  • Antimetabolite therapy for lesser-risk B-lineage acute lymphoblastic leukemia of childhood: a report from Children's Oncology Group Study P9201. 
  • Antimicrobial activity of PLUNC protects against Pseudomonas aeruginosa infection. 
  • Antiphospholipid syndrome: laboratory testing and diagnostic strategies. 
  • Antiretroviral therapy restores diversity in the T-cell receptor Vbeta repertoire of CD4 T-cell subpopulations among human immunodeficiency virus type 1-infected children and adolescents. 
  • Apo E structure determines VLDL clearance and atherosclerosis risk in mice. 
  • Apolipoprotein E and mimetic peptide initiate a calcium-dependent signaling response in macrophages. 
  • Apolipoprotein E and peptide mimetics modulate inflammation by binding the SET protein and activating protein phosphatase 2A. 
  • Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. 
  • Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus. 
  • Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay. 
  • Applications of Gene Editing Technologies to Cellular Therapies. 
  • Are 2 cords better than 1? 
  • Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. 
  • Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. 
  • Arsenic trioxide with ascorbic acid and high-dose melphalan: results of a phase II randomized trial. 
  • Assessing a role for enhancer-blocking activity in gene regulation within the murine T-cell receptor alpha/delta locus. 
  • Assessing immunophenotyping performance: proficiency-validation for adopting improved flow cytometry methods. 
  • Associated risk factors for silent cerebral infarcts in sickle cell anemia: low baseline hemoglobin, sex, and relative high systolic blood pressure. 
  • Association of HLA alleles with Plasmodium falciparum severity in Malian children. 
  • Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis. 
  • Associations between Complete Remissions (CRs) with 7+3 Induction Chemotherapy for Acute Myeloid Leukemia and 2-3 Year Survival ("Potential Cure") over the Past Four Decades: Analysis of SWOG Trial Data 
  • Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium. 
  • Augmentation of umbilical cord blood (UCB) transplantation with ex vivo-expanded UCB cells: results of a phase 1 trial using the AastromReplicell System. 
  • Auto-SCT for AML in second remission: CALGB study 9620. 
  • Autoantibody-mediated alteration of cellular adhesion: The role of plasminogen activator 
  • Autocrine and paracrine effects of atrial natriuretic peptide gene transfer on vascular smooth muscle and endothelial cellular growth. 
  • Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression. 
  • Autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for the treatment of persistent active EBV infection. 
  • Autologous Transplantation in Follicular Lymphoma with Early Therapy Failure: A National LymphoCare Study and Center for International Blood and Marrow Transplant Research Analysis. 
  • Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. 
  • Autologous stem cell transplantation for refractory or poor-risk relapsed Hodgkin's lymphoma: effect of the specific high-dose chemotherapy regimen on outcome. 
  • Autologous transplantation followed closely by reduced-intensity allogeneic transplantation as consolidative immunotherapy in advanced lymphoma patients: a feasibility study. 
  • Autophagy is essential for mitochondrial clearance in mature T lymphocytes. 
  • Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. 
  • Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. 
  • Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs. 
  • Azacitidine With Or Without Entinostat For The Treatment Of Therapy-Related Myeloid Neoplasm: Further Results Of The E1905 North American Leukemia Intergroup Study 
  • Azacitidine with or without Entinostat for the treatment of therapy-related myeloid neoplasm: further results of the E1905 North American Leukemia Intergroup study. 
  • B cell antigen receptor and CD40 differentially regulate CD22 tyrosine phosphorylation. 
  • B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity. 
  • B cell depletion reduces the development of atherosclerosis in mice. 
  • B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. 
  • B cells in chronic graft-versus-host disease. 
  • B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. 
  • B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions. 
  • B lymphocytes differentially influence acute and chronic allograft rejection in mice. 
  • B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction. 
  • B lymphocytes: how they develop and function. 
  • B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae. 
  • B-CAM/LU expression and the role of B-CAM/LU activation in binding of low- and high-density red cells to laminin in sickle cell disease. 
  • B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation. 
  • B-cell targeting in chronic graft-versus-host disease. 
  • B-lymphocyte contributions to human autoimmune disease. 
  • B-lymphocyte effector functions in health and disease. 
  • B10 cell regulation of health and disease. 
  • B10 cells: a functionally defined regulatory B cell subset. 
  • BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study. 
  • BAFF-ling autoantibodies. 
  • BATF Modulates the Th2 Locus Control Region and Regulates CD4+ T Cell Fate during Antihelminth Immunity. 
  • BCNU treatment of marrow stromal monolayers reversibly alters haematopoiesis. 
  • BIM deletion polymorphism profiling complements prognostic values of risk scores in imatinib-treated Asian chronic myeloid leukemia patients. 
  • BLyS and APRIL in rheumatoid arthritis. 
  • BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomide. 
  • BP1, a new homeobox gene, is frequently expressed in acute leukemias. 
  • Bacteremia, Sepsis, and Infective Endocarditis Associated with Staphylococcus aureus. 
  • Balance of Irgm protein activities determines IFN-gamma-induced host defense. 
  • Basal cell adhesion molecule Lutheran protein - The receptor critical for sickle cell adhesion to laminin (vol 101, pg 2550, 1998) 
  • Basal cell adhesion molecule/lutheran protein. The receptor critical for sickle cell adhesion to laminin. 
  • Baseline Predictors of Mortality in Patients with Relapsed or Refractory Acute Myeloid Leukemia Treated with Vosaroxin Plus Cytarabine or Placebo Plus Cytarabine in the Phase 3 VALOR Study 
  • Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia. 
  • Bathing the brain. 
  • Battle of the sex steroids in the male skeleton: and the winner is.... 
  • Bcr-Abl variants: biological and clinical aspects. 
  • Beliefs and Patterns of Practice in the Management of Hyperleukocytosis and Leukostasis Among Health Care Providers for Patients with Acute Leukemia: A Large North American Web-Based Survey 
  • Beneficial effects of cholecystokinin-receptor blockade and inhibition of proteolytic enzyme activity in experimental acute hemorrhagic pancreatitis in mice. Evidence for cholecystokinin as a major factor in the development of acute pancreatitis. 
  • Beta-arrestin-2 regulates the development of allergic asthma. 
  • Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. 
  • Betulinic acid derivatives as HIV-1 antivirals. 
  • Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease. 
  • Beyond the cardiac myofilament: hypertrophic cardiomyopathy- associated mutations in genes that encode calcium-handling proteins. 
  • Binding of polyreactive antibodies to self versus foreign antigens. 
  • Bioavailability of IgG administered by the subcutaneous route. 
  • Biochemical Underpinnings of Immune Cell Metabolic Phenotypes. 
  • Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits. 
  • Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. 
  • Biomarkers in chronic graft-versus-host disease: quo vadis? 
  • Bispecific antibodies engage T cells for antitumor immunotherapy. 
  • Blazing a new TRAIL in hematopoietic cell transplantation. 
  • Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication. 
  • Blood pressure homeostasis is maintained by a P311-TGF-β axis. 
  • Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding. 
  • Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses. 
  • Bone density loss after allogeneic hematopoietic stem cell transplantation: a prospective study. 
  • Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation. 
  • Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors. 
  • Boosting high-intensity focused ultrasound-induced anti-tumor immunity using a sparse-scan strategy that can more effectively promote dendritic cell maturation. 
  • Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition. 
  • Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder. 
  • Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease. 
  • Breaking bad blood: β2-microglobulin as a pro-aging factor in blood. 
  • Brincidofovir for Asymptomatic Adenovirus Viremia in Pediatric and Adult Allogeneic Hematopoietic Cell Transplant Recipients: A Randomized Placebo-Controlled Phase II Trial. 
  • Bromelain treatment decreases neutrophil migration to sites of inflammation. 
  • Bromelain treatment decreases secretion of pro-inflammatory cytokines and chemokines by colon biopsies in vitro. 
  • Build it and hope that enough of them will come. 
  • Building and maintaining the epithelium of the lung. 
  • Busulfan plus cyclophosphamide compared with total-body irradiation plus cyclophosphamide before marrow transplantation for myeloid leukemia: long-term follow-up of 4 randomized studies. 
  • Busulfan/melphalan is an effective and well tolerated conditioning regimen for pediatric AML and MDS patients receiving a matched sibling BMT 
  • Busulfan/melphalan/antithymocyte globulin followed by unrelated donor cord blood transplantation for treatment of infant leukemia and leukemia in young children: the Cord Blood Transplantation study (COBLT) experience. 
  • Bypassing complement: evolutionary lessons and future implications. 
  • C-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent. 
  • C75 inhibits food intake by increasing CNS glucose metabolism. 
  • CALGB 50604: Risk-adapted treatment of nonbulky early-stage Hodgkin lymphoma based on interim PET 
  • CAMP-mediated inhibition of the renal brush border membrane Na+-H+ exchanger requires a dissociable phosphoprotein cofactor. 
  • CCL3L1 and HIV/AIDS susceptibility. 
  • CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality. 
  • CCR2-antagonist prophylaxis reduces pulmonary immune pathology and markedly improves survival during influenza infection. 
  • CD1 expression by dendritic cells in human leprosy lesions: correlation with effective host immunity. 
  • CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies. 
  • CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation. 
  • CD19 expression levels regulate B lymphocyte development: human CD19 restores normal function in mice lacking endogenous CD19. 
  • CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes. 
  • CD19 regulates intrinsic B lymphocyte signal transduction and activation through a novel mechanism of processive amplification. 
  • CD19, CD21, and CD22: multifaceted response regulators of B lymphocyte signal transduction. 
  • CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse. 
  • CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. 
  • CD20 deficiency in humans results in impaired T cell-independent antibody responses. 
  • CD20: a regulator of cell-cycle progression of B lymphocytes 
  • CD22 and Siglec-G in B cell function and tolerance. 
  • CD22 cross-linking generates B-cell antigen receptor-independent signals that activate the JNK/SAPK signaling cascade. 
  • CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo. 
  • CD22 negatively and positively regulates signal transduction through the B lymphocyte antigen receptor. 
  • CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms. 
  • CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. 
  • CD22: a multifunctional receptor that regulates B lymphocyte survival and signal transduction. 
  • CD25+CD4+ regulatory T cell migration requires L-selectin expression: L-selectin transcriptional regulation balances constitutive receptor turnover. 
  • CD26 inhibition enhances allogeneic donor-cell homing and engraftment after in utero hematopoietic-cell transplantation. 
  • CD28 costimulatory signal induces protein arginine methylation in T cells. 
  • CD28 is required for germinal center formation. 
  • CD28 ligation induces rapid tyrosine phosphorylation of the linker molecule LAT in the absence of Syk and ZAP-70 tyrosine phosphorylation. 
  • CD34+CD38-lin- cord blood cells develop into dendritic cells in human thymic stromal monolayers and thymic nodules. 
  • CD4 T cells are required for CD8 T cell survival during both primary and memory recall responses. 
  • CD4 T follicular helper cell dynamics during SIV infection. 
  • CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse. 
  • CD4-independent binding of HIV-1 to the B lymphocyte receptor CR2 (CD21) in the presence of complement and antibody. 
  • CD40 expression by human fibroblasts. 
  • CD40 is a functional activation antigen and B7-independent T cell costimulatory molecule on normal human lung fibroblasts. 
  • CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis. 
  • CD44 antibody against In(Lu)-related p80, lymphocyte-homing receptor molecule inhibits the binding of human erythrocytes to T cells. 
  • CD4⁺ Thy1^- thymocytes with a Th-type 2 cytokine response 
  • CD5/CD8 T-cell subset depletion of bone marrow in HLA-non-identical and unrelated donor transplants compared with a comparable non-depleted control group. 
  • CD6-ligand interactions: a paradigm for SRCR domain function? 
  • CD6. 
  • CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines. 
  • CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver. 
  • CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells. 
  • CEA/CD3-bispecific T cell-engaging (BiTE) antibody-mediated T lymphocyte cytotoxicity maximized by inhibition of both PD1 and PD-L1. 
  • CEPP(B): an effective and well-tolerated regimen in poor-risk, aggressive non-Hodgkin's lymphoma. 
  • CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRbeta repertoire 
  • CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire. 
  • COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. 
  • CRISPR technology for gene therapy. 
  • CTLA-4-mediated inhibition of early events of T cell proliferation 
  • CTLA4Ig: bridging the basic immunology with clinical application. 
  • CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. 
  • CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. 
  • CXCR3 and CCR5 ligands in rheumatoid arthritis synovium. 
  • CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signalling through the T-cell receptor. 
  • Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development. 
  • Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller. 
  • Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells. 
  • Can the thymus win the battle against drug-resistant HIV? 
  • Can we agree on patient-reported outcome measures for assessing hematopoietic cell transplantation patients? A study from the CIBMTR and BMT CTN. 
  • Can we keep the "academic" in academic medicine? 2009 American Society for Clinical Investigation Presidential Address. 
  • Cancer immunotherapy innovator James Allison receives the 2015 Lasker~DeBakey Clinical Medical Research Award. 
  • Cancer immunotherapy: harnessing the immune system to battle cancer. 
  • Candidate counterparts of Sézary cells and adult T-cell lymphoma-leukaemia cells in normal peripheral blood: an ultrastructural study with the immunogold method and monoclonal antibodies. 
  • Carbon monoxide diffusion capacity: how low can you go for hematopoietic cell transplantation eligibility? 
  • Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. 
  • Cardiac fibroblasts in pressure overload hypertrophy: the enemy within? 
  • Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. 
  • Cardiac toxicity following high-dose cyclophosphamide, cisplatin, and BCNU (STAMP-I) for breast cancer. 
  • Cardiac xenografts between primate species provide evidence for the importance of the alpha-galactosyl determinant in hyperacute rejection. 
  • Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects. 
  • Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. 
  • Cardioprotective role of S-nitrosylated hemoglobin from rbc. 
  • Cardiopulmonary fitness in patients undergoing hematopoietic SCT: a pilot study. 
  • Cardiovascular Risk Factors in Survivors of Childhood Hematopoietic Cell Transplantation Treated with Total Body Irradiation: A Longitudinal Analysis. 
  • Carfilzomib, pomalidomide, and dexamethasone for relapsed or refractory myeloma. 
  • Casein kinase 1α-dependent feedback loop controls autophagy in RAS-driven cancers. 
  • Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy. 
  • Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology 
  • Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. 
  • Casting a smaller net into a bigger donor pool: A single center's experience with the new kidney allocation system. 
  • Catabolic pathways for streptokinase, plasmin, and streptokinase activator complex in mice. In vivo reaction of plasminogen activator with alpha 2-macroglobulin. 
  • Catabolism of human tissue plasminogen activator in mice. 
  • Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. 
  • Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate. 
  • Cell-Cycle Regulators and Cell Death in Immunity. 
  • Cell-Free DNA Is Elevated after Acute Arterial Injury in Infants 
  • Cellular and molecular targeting for nanotherapeutics in transplantation tolerance. 
  • Central nervous system bleeding in hemophiliacs. 
  • Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance. 
  • Certolizumab pegol. 
  • ChREBP regulates fructose-induced glucose production independently of insulin signaling. 
  • Challenges and opportunities for international cooperative studies in pediatric hematopoeitic cell transplantation: priorities of the Westhafen Intercontinental Group. 
  • Challenges in the pursuit of immune tolerance. 
  • Changes in primary lymphoid organs with aging. 
  • Changes in the pattern of cytogenetic aberrations with advancing age in acute myeloid (Non-APL) leukemia: A Southwest Oncology study (S9007). 
  • Changing patterns of chemotherapy relative dose intensity and supportive care for aggressive B-cell non-Hodgkin lymphoma. 
  • Characteristics of Late Fatal Infections after Allogeneic Hematopoietic Cell Transplantation. 
  • Characterization and affinity isolation of xenoreactive human natural antibodies. 
  • Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis 
  • Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis. 
  • Characterization of Leu777Pro and Ile865Thr type IIA von Willebrand disease mutations. 
  • Characterization of a B lymphoblastoid cell line mutant that secretes HLA-A2. 
  • Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes. 
  • Characterization of a monoclonal antibody, RTE-21, that binds to keratohyalin granule-associated proteins in epithelial cells of human skin and thymus. 
  • Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies. 
  • Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger. 
  • Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. 
  • Characterization of an oligopeptide chemoattractant receptor on human blood monocytes using a new radioligand. 
  • Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. 
  • Characterization of cord blood natural killer and lymphokine activated killer lymphocytes following ex vivo cellular engineering. 
  • Characterization of human CD7 transgenic mice. 
  • Characterization of human thymic epithelial cell surface antigens: phenotypic similarity of thymic epithelial cells to epidermal keratinocytes. 
  • Characterization of lung inflammation and its impact on macrophage function in aging. 
  • Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus. 
  • Chemoattractant receptors on phagocytic cells. 
  • Chemoattractant-induced activation of c-fos gene expression in human monocytes. 
  • Chemokine 25-induced signaling suppresses colon cancer invasion and metastasis. 
  • Chemokine production by G protein-coupled receptor activation in a human mast cell line: roles of extracellular signal-regulated kinase and NFAT. 
  • Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge. 
  • Chemokines as adjuvants for immunotherapy: implications for immune activation with CCL3. 
  • Chemotactic factor and P15E-related chemotaxis inhibitor in human melanoma cell lines with different macrophage content and tumorigenicity in nude mice. 
  • Chemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia. 
  • Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10. 
  • Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction. 
  • Cholera in Haiti and Other Caribbean Regions, 19th Century 
  • Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with non-replicating antigens. 
  • Chromatin Dynamics and the Development of the TCRα and TCRδ Repertoires. 
  • Chronic Graft-versus-Host Disease: A Long Road Ahead. 
  • Chronic dry eye disease is principally mediated by effector memory Th17 cells. 
  • Chronic graft-versus-host disease and other late complications of bone marrow transplantation. 
  • Chronic lymphocytic leukemia (CLL) cell CD38 expression and inducible nitric oxide synthase (NOS2) expression are associated with serum IL-4 levels. 
  • Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function. 
  • Chronic lymphocytic leukemia cells (CLL) express the neuronal isoform of nitric oxide synthase (NOS1), and NOS1-specific inhibitors induce CLL cell death. 
  • Cigarette smoke and inflammation: role in cerebral aneurysm formation and rupture. 
  • Cilia loss sensitizes cells to transformation by activating the mevalonate pathway. 
  • Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators. 
  • Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults. 
  • Circulating endothelial cells in Kawasaki disease. 
  • Cirrhosis of the liver in long-term marrow transplant survivors. 
  • Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma. 
  • Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivo. 
  • Clinical Characteristics and Quality of Life of Children with ITP Starting Second Line Treatments: Data from the ITP Consortium of North America ICON1 Study 
  • Clinical Characteristics of Hyposecretory Multiple Myeloma (Monoclonal Immunoglobulin < 3 g/dl) in Afro-Caribbean Patients at a Single Urban Institution 
  • Clinical Outcomes of Microtransplantation for Older Adults with Acute Myeloid Leukemia 
  • Clinical and biologic features predict a poor prognosis in acute lymphoid leukemias in infants: a Pediatric Oncology Group Study. 
  • Clinical and immunologic effects of prolonged infusion of low-dose recombinant interleukin-2 after autologous and T-cell-depleted allogeneic bone marrow transplantation. 
  • Clinical and laboratory diagnosis of von Willebrand disease: a synopsis of the 2008 NHLBI/NIH guidelines. 
  • Clinical and metabolic correction of pompe disease by enzyme therapy in acid maltase-deficient quail. 
  • Clinical and metabolomic risk factors associated with rapid renal function decline in sickle cell disease. 
  • Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia. 
  • Clinical applications of filgrastim and stem cell factor in vivo and in vitro. 
  • Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency. 
  • Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • Clinical outcomes of splenectomy in children: report of the splenectomy in congenital hemolytic anemia registry. 
  • Clinical risks and healthcare utilization of hematopoietic cell transplantation for sickle cell disease in the USA using merged databases. 
  • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. 
  • Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study. 
  • Clinician Approaches to Myeloma in Academia and the Community : An in-Practice Qualitative Study 
  • Clinicopathologic and genetic spectrum of infantile B-lymphoblastic leukemia: a multi-institutional study. 
  • Clofarabine Plus Busulfan is an Effective Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Lymphoblastic Leukemia: Long-Term Study Results. 
  • Clofarabine combined with busulfan provides excellent disease control in adult patients with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation. 
  • Clofarabine ± fludarabine with once daily i.v. busulfan as pretransplant conditioning therapy for advanced myeloid leukemia and MDS. 
  • Clonal analysis of human anti-V3 monoclonal antibodies selected by a V3 tetramer. 
  • Cloned mice have an obese phenotype not transmitted to their offspring. 
  • Cloning and characterization of the chronic neutrophilic leukemia-associated P230 BCR/ABL oncogene. 
  • Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. 
  • Co-option of endocytic functions of cellular caveolae by pathogens. 
  • Coadministration of IL-12 or IL-10 expression cassettes drives immune responses toward a Th1 phenotype. 
  • Coagulation activation in sickle cell trait: an exploratory study 
  • Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. 
  • Coenzyme Q10 protects ischemic myocardium in an open-chest swine model. 
  • Coexistence of a chemotactic factor and a retroviral P15E-related chemotaxis inhibitor in human tumor cell culture supernatants. 
  • Coexistent naïve phenotype and higher cycling rate of cord blood T cells as compared to adult peripheral blood. 
  • Cognitive problems following hematopoietic stem cell transplant: relationships with sleep, depression and fatigue. 
  • Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium. 
  • Collaborative study of marrow transplantation for sickle cell disease: Aspects specific for transplantation of hemoglobin disorders 
  • Colonization, pathogenicity, host susceptibility, and therapeutics for Staphylococcus aureus: what is the clinical relevance? 
  • Combination antifungal therapy: what can and should we expect? 
  • Combination of datmorubicin and cytarabine chemotherapy with gemtuzumab ozogamicin as initial therapy for elderly patients with previously untreated acute myeloid leukemia. 
  • Combination treatment of bullous pemphigoid with anti-CD20 and anti-CD25 antibodies in a patient with chronic graft-versus-host disease. 
  • Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression. 
  • Coming of age: molecular drivers of aging and therapeutic opportunities. 
  • Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. 
  • Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10. 
  • Common variants within 6p21.31 locus are associated with chronic lymphocytic leukaemia and, potentially, other non-Hodgkin lymphoma subtypes (vol 159, pg 572, 2012) 
  • Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. 
  • Comparable Outcomes of Patients Eligible Versus Ineligible for Southwest Oncology Group (SWOG) Leukemia Studies 
  • Comparable outcomes of patients eligible vs ineligible for SWOG leukemia studies. 
  • Comparative analysis of antigen loading strategies of dendritic cells for tumor immunotherapy. 
  • Comparative analysis of type 2b von Willebrand disease mutations: implications for the mechanism of von Willebrand factor binding to platelets. 
  • Comparative and functional evaluation of in vitro generated to ex vivo CD8 T cells. 
  • Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker. 
  • Comparison of characteristics from White- and Black-Americans with venous thromboembolism: a cross-sectional study. 
  • Comparison of human immunodeficiency virus antigens as stimulants for lymphocyte proliferation assays. 
  • Comparison of interlaboratory variation in absolute T-cell counts by single-platform and optimized dual-platform methods. 
  • Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD-AF and treated with vitamin K antagonists. 
  • Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders. 
  • Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies. 
  • Comparison of reduced-intensity hematopoietic cell transplantation with chemotherapy in patients age 60-70 years with acute myelogenous leukemia in first remission. 
  • Comparison of systemic and mucosal vaccination: impact on intravenous and rectal SIV challenge. 
  • Comparison of the intestinal and serum antibody response in patients with dermatitis herpetiformis 
  • Comparison of thymocyte development and cytokine production in CD7-deficient, CD28-deficient and CD7/CD28 double-deficient mice. 
  • Comparison of two long-term chemotherapy regimens, with or without agents to modify skeletal repair, in multiple myeloma. 
  • Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation. 
  • Complement component 1 inhibitor (C1-INH) like protein on murine spermatozoa: anti-C1-INH inhibits in vitro fertilization. 
  • Complementary roles for CD19 and Bruton's tyrosine kinase in B lymphocyte signal transduction. 
  • Complete Remissions (CRs) with Azacitidine Regimens Compared to Crs with 7+3 Induction Chemotherapy and the Effect on Overall Survival 
  • Complete Response to Clofarabine Is Durable and Correlates with Survival in Previously Untreated Older Adult Patients with Acute Myeloid Leukemia (AML) and Unfavorable Prognostic Factors 
  • Complex Antigens Drive Permissive Clonal Selection in Germinal Centers. 
  • Complex immune correlates of protection in HIV-1 vaccine efficacy trials. 
  • Complications of implantable venous access devices in patients with sickle cell disease. 
  • Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence. 
  • Conditional and unconditional estimation of multidimensional quality of life after hematopoietic stem cell transplantation: a longitudinal follow-up of 415 patients. 
  • Conditional stabilization of beta-catenin expands the pool of lung stem cells. 
  • Conditioning therapy with intravenous busulfan and cyclophosphamide (IV BuCy2) for hematologic malignancies prior to allogeneic stem cell transplantation: a phase II study. 
  • Connect MM® - the Multiple Myeloma Disease Registry: incidence of second primary malignancies in patients treated with lenalidomide. 
  • Consensus guidelines on plasma cell myeloma minimal residual disease analysis and reporting. 
  • Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals. 
  • Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy 
  • Construction and destruction of MHC class I in the peptide-loading complex. 
  • Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses. 
  • Contemporary experience with high-dose interleukin-2 therapy and impact on survival in patients with metastatic melanoma and metastatic renal cell carcinoma. 
  • Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies. 
  • Contrasting Adult and Infant Immune Responses to HIV Infection and Vaccination. 
  • Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries. 
  • Control of IFN-alphaA by CD73: implications for mucosal inflammation. 
  • Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability. 
  • Control of simian/human immunodeficiency virus viremia and disease progression after IL-2-augmented DNA-modified vaccinia virus Ankara nasal vaccination in nonhuman primates. 
  • Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3. 
  • Control of the innate immune response by the mevalonate pathway. 
  • Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR. 
  • Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes. 
  • Conversion of an immunogenic human immunodeficiency virus (HIV) envelope synthetic peptide to a tolerogen in chimpanzees by the fusogenic domain of HIV gp41 envelope protein. 
  • Copper in microbial pathogenesis: meddling with the metal. 
  • Cord Blood Transplantation Study (COBLT): cord blood bank standard operating procedures. 
  • Cord blood derived cell therapy product, DUOC-01, accelerates remyelination in a murine model of cuprizone induced demyelination 
  • Cord blood for brain injury 
  • Cord blood for brain injury. 
  • Cord blood is the optimal graft source for the treatment of pediatric patients with lysosomal storage diseases: clinical outcomes and future directions. 
  • Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model. 
  • Coronatine promotes Pseudomonas syringae virulence in plants by activating a signaling cascade that inhibits salicylic acid accumulation. 
  • Correction: SP-A Preserves Airway Homeostasis during Mycoplasma pneumoniae Infection in Mice. 
  • Correction: phase 1 clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibtion. 
  • Correlating notch signaling with thymocyte maturation. 
  • Correlation between erythrocyte CR1 reduction and other blood proteinase markers in patients with malignant and inflammatory disorders. 
  • Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition. 
  • Corrigendum: Genomic signatures to guide the use of chemotherapeutics (Nature Medicine (2006) 12, (1294-1300)) 
  • Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus. 
  • Cost-Effectiveness of Blood Transfusions Versus Observation for Silent Cerebral Infarcts from the Silent Cerebral Infarct Trial 
  • Costs and length of stay for patients with and without sickle cell disease after hysterectomy, appendectomy, or knee replacement. 
  • Country-Level Macroeconomic Indicators Predict Early Post-Allogeneic Hematopoietic Cell Transplantation Survival in Acute Lymphoblastic Leukemia: A CIBMTR Analysis. 
  • Creating meaningful health care reform. 
  • Critical role for mouse marginal zone B cells in PF4/heparin antibody production. 
  • Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. 
  • Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation. 
  • Crossing the bridge: large animal models in translational transplantation research. 
  • Crosstransplantation of kidneys in normal and Hyp mice. Evidence that the Hyp mouse phenotype is unrelated to an intrinsic renal defect. 
  • Crucial role for the VWF A1 domain in binding to type IV collagen. 
  • Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing. 
  • Cryptococcosis: a model for the understanding of infectious diseases. 
  • Cryptococcus neoformans copper detoxification machinery is critical for fungal virulence. 
  • Cumulative incidence of secondary solid malignant tumors in aplastic anemia patients given marrow grafts after conditioning with chemotherapy alone. 
  • Current Diagnosis Patterns for Acute Myeloid Leukemia (AML) in Clinical Practice Compared with World Health Organization (WHO) 2008 Recommendations: Outcomes from the CONNECT (R) Myelodysplastic Syndromes (MDS) and AML Disease Registry 
  • Current therapies and future possibilities for drug development against liver-stage malaria. 
  • Cutting Edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development. 
  • Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo 
  • Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes. 
  • Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells. 
  • Cutting edge: C3d functions as a molecular adjuvant in the absence of CD21/35 expression. 
  • Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses. 
  • Cutting edge: TGF-beta-induced expression of Foxp3 in T cells is mediated through inactivation of ERK. 
  • Cutting edge: a role for the adaptor protein LAT in human NK cell-mediated cytotoxicity. 
  • Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. 
  • Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation. 
  • Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice. 
  • Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells. 
  • Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling. 
  • Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling. 
  • Cyclosporine v methotrexate for graft-v-host disease prevention in patients given marrow grafts for leukemia: long-term follow-up of three controlled trials. 
  • Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation. 
  • Cytokine expression in vivo during murine herpetic stromal keratitis. Effect of protective antibody therapy. 
  • Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization. 
  • Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells. 
  • Cytokine transcriptional events during helper T cell subset differentiation. 
  • Cytokines, leptin, and stress-induced thymic atrophy. 
  • Cytokines: the future of intranasal vaccine adjuvants. 
  • Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis. 
  • D-dimer antigen: current concepts and future prospects. 
  • DNA Priming Increases Frequency of T-Cell Responses to a Vesicular Stomatitis Virus HIV Vaccine with Specific Enhancement of CD8+ T-Cell Responses by Interleukin-12 Plasmid DNA. 
  • DQB1*03:19 ASSOCIATION WITH DRB1 AND DQA1 IN NORTH CAROLINA POPULATION. 
  • DUOC-01, A CANDIDATE CELL THERAPY PRODUCT DERIVED FROM BANKED CORD BLOOD, ACCELERATES BRAIN REMYELINATION IN NSG MICE FOLLOWING CUPRIZONE FEEDING 
  • Danger signals in regulating the immune response to solid organ transplantation. 
  • Dangerous liaisons: flirtations between oncogenic BRAF and GRP78 in drug-resistant melanomas. 
  • Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia. 
  • Death-associated protein kinase 1 promotes growth of p53-mutant cancers. 
  • Deciphering the tête-à-tête between the microbiota and the immune system. 
  • Declining Rates of Treatment-Related Mortality in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) Given "Intensive" Induction Regimens: A Report From the Southwest Oncology Group (SWOG) and MD Anderson Cancer Center (MDA) 
  • Declining rates of treatment-related mortality in patients with newly diagnosed AML given 'intense' induction regimens: a report from SWOG and MD Anderson. 
  • Decreased circulating macrophage migration inhibitory factor (MIF) protein and blood mononuclear cell MIF transcripts in children with Plasmodium falciparum malaria. 
  • Decreased fibrinolytic activity in porcine-to-primate cardiac xenotransplantation. 
  • Decreased incidence of marrow graft rejection in patients with severe aplastic anemia: changing impact of risk factors. 
  • Decreased normal NK-cells is a characteristic of T-cell large granular lymphocytic leukemia and is strongly associated with cytopenia. 
  • Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice. 
  • Decreased survival in hepatitis C patients with monomorphic post-transplant lymphoproliferative disorder after liver transplantation treated with frontline immunochemotherapy. 
  • Defective T cell development and function in the absence of Abelson kinases. 
  • Defensins in innate antiviral immunity. 
  • Defibrotide (DF) for the treatment of severe veno-occlusive disease (sVOD) and multi-organ failure (MOF) post SCT: Final results of a multi-center, randomized, dose-finding trial. 
  • Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation: a multicenter, randomized, dose-finding trial. 
  • Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. 
  • Deficiency in MyD88 Signaling Results in Decreased Antibody Responses to an Adeno-Associated Virus Vector in Murine Pompe Disease. 
  • Defining a second epitope for heparin-induced thrombocytopenia/thrombosis antibodies using KKO, a murine HIT-like monoclonal antibody. 
  • Defining the Genomic Make up of Acute Myeloid Leukemia in Adolescents and Young Adults (AYA): Report from COG AAML03P1, AAML531 and SWOG S0106 
  • Definitions of the phenotypic manifestations of sickle cell disease. 
  • Degradation of collagen by a human granulocyte collagenolytic system. 
  • Degradation of the epidermal-dermal junction by proteolytic enzymes from human skin and human polymorphonuclear leukocytes. 
  • Degradation of von Willebrand factor in patients with acquired clinical conditions in which there is heightened proteolysis. 
  • Delayed apoptosis of circulating neutrophils in Kawasaki disease. 
  • Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis 
  • Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC. 
  • Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. 
  • Delineation of immunologically and biochemically distinct HLA-A2 antigens. 
  • Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. 
  • Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta. 
  • Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models. 
  • Dendritic cell-based immunotherapy. 
  • Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. 
  • Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells. 
  • Dendritic cells infected with a vaccinia vector carrying the human gp100 gene simultaneously present multiple specificities and elicit high-affinity T cells reactive to multiple epitopes and restricted by HLA-A2 and -A3. 
  • Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. 
  • Dendritic epidermal T cells regulate skin antimicrobial barrier function. 
  • Dengue virus-induced autophagy regulates lipid metabolism. 
  • Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines. 
  • Depression of lymphocyte transformation and exacerbation of Behcet's syndrome by ingestion of english walnuts. 
  • Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group. 
  • Design and Patient Characteristics of the Chronic Graft-versus-Host Disease Response Measures Validation Study 
  • Designer monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer. 
  • Detection of amino-terminal extracellular domain of somatostatin receptor 2 by specific monoclonal antibodies and quantification of receptor density in medulloblastoma. 
  • Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation. 
  • Detection of minimal residual T cell acute lymphoblastic leukemia by flow cytometry. 
  • Detection of pathogen-specific antibodies by loop-mediated isothermal amplification. 
  • Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging. 
  • Determinants of PF4/heparin immunogenicity. 
  • Determinants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA era 
  • Determination of the primary structures of human skin chymase and cathepsin G from cutaneous mast cells of urticaria pigmentosa lesions. 
  • Determining γδ versus αß T cell development. 
  • Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination. 
  • Developing aptamers into therapeutics. 
  • Development and implementation of a proficiency testing program for Luminex bead-based cytokine assays. 
  • Development and validation of a predictive model for chemotherapy-associated thrombosis. 
  • Development and validation of a rapid, aldehyde dehydrogenase bright-based cord blood potency assay. 
  • Development of a bead immunoassay to measure Vi polysaccharide-specific serum IgG after vaccination with the Salmonella enterica serovar Typhi Vi polysaccharide. 
  • Development of a contemporary globally diverse HIV viral panel by the EQAPOL program. 
  • Development of a novel screen for protease inhibitors. 
  • Development of an Online Patient Decision Aid for Previously Treated Mantle Cell Lymphoma 
  • Development of pemphigus vulgaris-like lesions in severe combined immunodeficiency disease mice reconstituted with lymphocytes from patients. 
  • Development of specific receptors for N-formylated chemotactic peptides in a human monocyte cell line stimulated with lymphokines. 
  • Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance. 
  • Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer. 
  • Diacylglycerol kinase zeta regulates microbial recognition and host resistance to Toxoplasma gondii 
  • Diacylglycerol kinase zeta regulates microbial recognition and host resistance to Toxoplasma gondii. 
  • Diacylglycerol kinases in immune cell function and self-tolerance. 
  • Diagnosis, Treatment and Long-Term Follow Up of Patients with ADA Deficiency: a Single-Center Experience. 
  • Dibutyryl cyclic adenosine monophosphate reduces expression of c-myc during HL-60 differentiation. 
  • Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. 
  • Differences in prognostic factors and outcomes in African Americans and whites with acute myeloid leukemia. 
  • Different patterns of relapse associated with three intensive treatment regimens for pediatric E-rosette positive T-cell leukemia: a Pediatric Oncology Group study. 
  • Differential Impact of HLA-A, -B, and -DRB1 Mismatching in Relation to Other Variables on the Outcomes of Myeloablative Unrelated Single Donor Umbilical Cord Blood Transplantation From 4/6 Matched Units in Children and Young Adults 
  • Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma. 
  • Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge. 
  • Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines. 
  • Differential expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas. 
  • Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis. 
  • Differential regulation of accessory mitogenic signaling receptors by the T cell antigen receptor. 
  • Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases. 
  • Differential requirement for the SAP-Fyn interaction during NK T cell development and function. 
  • Differential requirement of RasGRP1 for γδ T cell development and activation. 
  • Differential stimulation of the respiratory burst and lysosomal enzyme secretion in human polymorphonuclear leukocytes by synthetic diacylglycerols. 
  • Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci. 
  • Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation. 
  • Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme. 
  • Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells. 
  • Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. 
  • Discontinuous expression of a membrane antigen (HB-7) during B lymphocyte differentiation. 
  • Disease severity in rheumatoid arthritis: relationships of plasma tumor necrosis factor-alpha, soluble interleukin 2-receptor, soluble CD4/CD8 ratio, neopterin, and fibrin D-dimer to traditional severity and functional measures. 
  • Disparity in the kinetics of onset of hypermutation in immunoglobulin heavy and light chains. 
  • Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity. 
  • Disruption of diacylglycerol metabolism impairs the induction of T cell anergy. 
  • Disruption of mindin exacerbates cardiac hypertrophy and fibrosis. 
  • Disruption of the Ang II type 1 receptor promotes longevity in mice. 
  • Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. 
  • Dissemination and commercialization of hematopoietic progenitor cell transplantation. 
  • Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells. 
  • Distinct Responses of Stem Cells to Telomere Uncapping-A Potential Strategy to Improve the Safety of Cell Therapy. 
  • Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1. 
  • Distinct populations of CD4+helper T cells generate CD4 and CD8 memory responses to infection 
  • Distinct roles for c-Myb and core binding factor/polyoma enhancer-binding protein 2 in the assembly and function of a multiprotein complex on the TCR delta enhancer in vivo. 
  • Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system. 
  • Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. 
  • Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. 
  • Divergent functions of angiotensin II receptor isoforms in the brain. 
  • Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms. 
  • Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects. 
  • Dna Ligase IV Deficiency With Novel Compound Heterozygous Mutations 
  • Does Living Closer to a Medical Care Center Matter in Sickle Cell Disease? 
  • Dolph Oliver Adams, M.D., Ph.D 
  • Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency. 
  • Donor body mass index does not predict graft versus host disease following hematopoietic cell transplantation 
  • Donor buffy coat cell infusion after marrow transplantation for aplastic anemia. 
  • Donor immune reconstitution after liver-small bowel transplantation for multiple intestinal atresia with immunodeficiency. 
  • Donor leukocyte infusions in recurrent Hodgkin lymphoma following allogeneic stem cell transplant: 10-year experience at the M. D. Anderson Cancer Center. 
  • Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease. 
  • Dose-intense chemoimmunotherapy plus radioimmunotherapy in high-risk diffuse large B-cell lymphoma and mantle cell lymphoma: a phase II study. 
  • Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemia. 
  • Down syndrome childhood acute lymphoblastic leukemia has a unique spectrum of sentinel cytogenetic lesions that influences treatment outcome: a report from the Children's Oncology Group. 
  • Dr(a-) polymorphism of decay accelerating factor. Biochemical, functional, and molecular characterization and production of allele-specific transfectants. 
  • Driving an improved CAR for cancer immunotherapy. 
  • Dry powder vaccines for mucosal administration: critical factors in manufacture and delivery. 
  • Dual antigen transfer pathways mediate highly efficacious anti-tumor immunity induced by intravenously injected antigen loaded monocytes 
  • Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity. 
  • Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity. 
  • Dual targeting of the thioredoxin and glutathione systems in cancer and HIV. 
  • Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells. 
  • Durable Chimerism and Long-Term Survival after Unrelated Umbilical Cord Blood Transplantation for Pediatric Hemophagocytic Lymphohistiocytosis: A Single-Center Experience. 
  • Durable Engraftment and Correction of Genetic Defect in Children with Congenital Amegakaryocytic Thrombocytopenia Following Myeloablative Umbilical Cord Blood Transplantation 
  • Durable Overall Survival Benefit in Patients >= 60 Years with Relapsed or Refractory AML Treated with Vosaroxin/Cytarabine Vs Placebo/Cytarabine: Updated Results from the Valor Trial 
  • Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury. 
  • Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. 
  • Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants. 
  • Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia. 
  • Dynamic microRNA gene transcription and processing during T cell development. 
  • Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome. 
  • Dysfunctional T cell metabolism in the tumor microenvironment. 
  • E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression. 
  • E2A promotes the survival of precursor and mature B lymphocytes. 
  • E3 ligase FBXW7 aggravates TMPD-induced systemic lupus erythematosus by promoting cell apoptosis 
  • EBV Noncoding RNAs. 
  • EGF Accelerates Hematopoietic Stem Cell Regeneration Following 5-FU Chemotherapy Via G-CSF Receptor Signaling 
  • EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis. 
  • EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells. 
  • ENESTgoal Treatment-Free Remission Study: Updated Preliminary Results and Digital Polymerase Chain Reaction Analysis in Patients with Chronic Myeloid Leukemia in Chronic Phase Who Switched from Imatinib to Nilotinib 
  • ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. 
  • EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma. 
  • ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum. 
  • Early Allogeneic Stem Cell Transplantation Appears to Improve Outcomes in Adult T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL/T-LBL) Patients: A Multi-Institutional Review 
  • Early Allogeneic Stem Cell Transplantation and Use of Asparaginase during Induction Chemotherapy Appear to Improve Otherwise Poor Outcomes in Adult T Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL/T-LBL) Patients: A Multi Institutional Review 
  • Early Failure of Frontline Rituximab-Containing Chemo-immunotherapy in Diffuse Large B Cell Lymphoma Does Not Predict Futility of Autologous Hematopoietic Cell Transplantation 
  • Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry. 
  • Early failure of frontline rituximab-containing chemo-immunotherapy in diffuse large B cell lymphoma does not predict futility of autologous hematopoietic cell transplantation. 
  • Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint. 
  • Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock 
  • Early relapse after autologous hematopoietic cell transplantation remains a poor prognostic factor in multiple myeloma but outcomes have improved over time. 
  • Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. 
  • Easy-to-Read Informed Consent Form for Hematopoietic Cell Transplantation Clinical Trials: Results from the Blood and Marrow Transplant Clinical Trials Network 1205 Study 
  • Economic analysis of conventional-dose chemotherapy compared with high-dose chemotherapy plus autologous hematopoietic stem-cell transplantation for metastatic breast cancer. 
  • Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. 
  • Editorial overview: Metabolism of T cells: integrating nutrients, signals, and cell fate. 
  • Editorial position on publishing articles on human organ transplantation. 
  • Educating Pediatric Outpatient Nurses to the Unique Challenges of Reduced Intensity Transplant Conditioning (RIC) Regimen in Children With Non-Malignant Disorders 
  • Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity. 
  • Effect of FXIII Polymorphism on Formation of Heterocellular Aggregates in SCD 
  • Effect of HLA-matching recipients to donor noninherited maternal antigens on outcomes after mismatched umbilical cord blood transplantation for hematologic malignancy. 
  • Effect of Minimal Residual Disease (MRD) Information on Prediction of Relapse and Survival in Adult Acute Myeloid Leukemia 
  • Effect of anti-V3 antibodies on cell-free and cell-to-cell human immunodeficiency virus transmission. 
  • Effect of bismuth salts on systemic and mucosal immune responses to orally administered cholera toxin. 
  • Effect of measurable ('minimal') residual disease (MRD) information on prediction of relapse and survival in adult acute myeloid leukemia. 
  • Effect of pregnancy and human immunodeficiency virus infection on intracellular interleukin-2 production patterns. 
  • Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans. 
  • Effect of thymectomy on peripheral lymphocyte subsets in myasthenia gravis: selective effect on T-cells in patients with thymic atrophy. 
  • Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor. 
  • Effective asparagine depletion with pegylated asparaginase results in improved outcomes in adult acute lymphoblastic leukemia: Cancer and Leukemia Group B Study 9511. 
  • Effectiveness of etoposide chemomobilization in lymphoma patients undergoing auto-SCT. 
  • Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK. 
  • Effects of cranial radiation in children with high risk T cell acute lymphoblastic leukemia: a Pediatric Oncology Group report. 
  • Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial 
  • Effects of human immunodeficiency virus type 1 on CD4 lymphocyte subset activation. 
  • Effects of hydroxyurea treatment for patients with hemoglobin SC disease. 
  • Effects of progesterone and estradiol sex hormones on the release of microparticles by RAW 264.7 macrophages stimulated by Poly(I:C). 
  • Efficacy and Safety of Pembrolizumab in Patients Enrolled in KEYNOTE-030 in the United States: An Expanded Access Program. 
  • Efficacy and safety of CMA-676 in patients with AML in first relapse. 
  • Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal™) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study. 
  • Efficacy and safety of hematopoietic stem cell remobilization with plerixafor+G-CSF in adult patients with germ cell tumors. 
  • Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia. 
  • Efficacy and toxicity of 9-beta-D-arabinofuranosylguanine (araG) as an agent to purge malignant T cells from murine bone marrow: application to an in vivo T-leukemia model. 
  • Efficacy of Pharmacokinetics-Directed Busulfan, Cyclophosphamide, and Etoposide Conditioning and Autologous Stem Cell Transplantation for Lymphoma: Comparison of a Multicenter Phase II Study and CIBMTR Outcomes. 
  • Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I. 
  • Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I. 
  • Efficient Culture of Human Naive and Memory B Cells for Use as APCs. 
  • Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. 
  • Efficient lymphocyte migration across high endothelial venules of mouse Peyer's patches requires overlapping expression of L-selectin and beta7 integrin. 
  • Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis. 
  • Elevated expression of numerous interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis. 
  • Elevated level of peripheral CD8(+)CD28(-) T lymphocytes are an independent predictor of progression-free survival in patients with metastatic breast cancer during the course of chemotherapy. 
  • Elevated serum levels of matrix metalloproteinase-9 (MMP-9) in Kawasaki disease. 
  • Elevated soluble interleukin-2 receptor in childhood hemophagocytic histiocytic syndromes. 
  • Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. 
  • Eliglustat maintains long-term clinical stability in patients with Gaucher disease type 1 stabilized on enzyme therapy. 
  • Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency virus. 
  • Emerging applications of aptamers for anticoagulation and hemostasis. 
  • Emerging pathways for hereditary axonopathies. 
  • Emerging therapeutic approaches in the management of retinal angiogenesis and edema. 
  • Empiric Definition of Eligibility Criteria for Clinical Trials in Relapsed/Refractory AML: Analysis of 1,892 Patients from HOVON/SAKK and SWOG 
  • Empiric definition of eligibility criteria for clinical trials in relapsed/refractory acute myeloid leukemia: analysis of 1,892 patients from HOVON/SAKK and SWOG. 
  • Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. 
  • Endothelial Heparan Sulfate Controls Chemokine Presentation in Recruitment of Lymphocytes and Dendritic Cells to Lymph Nodes 
  • Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26. 
  • Endpoints for clinical trials testing treatment of acute graft-versus-host disease: a joint statement. 
  • Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation. 
  • Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus. 
  • Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. 
  • Engineering musculoskeletal tissues with human embryonic germ cell derivatives. 
  • Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. 
  • Enhanced T cell responses due to diacylglycerol kinase zeta deficiency. 
  • Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes. 
  • Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells. 
  • Enhanced interleukin-8 release and gene expression in macrophages after exposure to Mycobacterium tuberculosis and its components. 
  • Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein. 
  • Enhanced priming of adaptive immunity by Mycobacterium smegmatis mutants with high-level protein secretion. 
  • Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis. 
  • Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery. 
  • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. 
  • Enhancer-blocking activity within the DNase I hypersensitive site 2 to 6 region between the TCR alpha and Dad1 genes. 
  • Enhancing dendritic cell-based vaccination for highly aggressive glioblastoma. 
  • Enumerating antigen-specific T-cell responses in peripheral blood: a comparison of peptide MHC Tetramer, ELISpot, and intracellular cytokine analysis. 
  • Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease. 
  • Epidemiologic and economic consequences of the global epidemics of obesity and diabetes. 
  • Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration. 
  • Epidermal growth factor regulates hematopoietic regeneration after radiation injury. 
  • Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage. 
  • Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer. 
  • Epinephrine acts through erythroid signaling pathways to activate sickle cell adhesion to endothelium via LW-alphavbeta3 interactions. 
  • Epinephrine-induced activation of LW-mediated sickle cell adhesion and vaso-occlusion in vivo. 
  • Epiregulin and EGFR interactions are involved in pain processing. 
  • Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis 
  • Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis 
  • Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. 
  • Epithelial-mesenchymal transitions and hepatocarcinogenesis. 
  • Epitope specificity of anti-La antibodies from patients with Sjögren's syndrome. 
  • Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 
  • Epitope-specific signaling through CD45 on T lymphocytes leads to cAMP synthesis in monocytes after ICAM-1-dependent cellular interaction. 
  • Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication. 
  • Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases. 
  • Equivalence of 2 effective graft-versus-host disease prophylaxis regimens: results of a prospective double-blind randomized trial. 
  • Erratum: CORRIGENDUM: Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer 
  • Erratum: Corrigendum: Epidemiologic and economic consequences of the global epidemics of obesity and diabetes 
  • Erratum: Corrigendum: Protection against malaria at 1 year and immune correlates following PfSPZ vaccination 
  • Erratum: Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel 
  • Erratum: Genomic signatures to guide the use of chemotherapeutics (Nature (2006) 12, (1294-1300)) 
  • Erratum: Genomic signatures to guide the use of chemotherapeutics (Nature Medicine (2006) 12 (1294-1300)) 
  • Erratum: Regenerating functional myocardium: Improved performance after skeletal myoblast transplantation 
  • Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution. 
  • Erythrocyte blood group antigens: not so simple after all. 
  • Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium. 
  • Escalation of daunorubicin and addition of etoposide in the ADE regimen in acute myeloid leukemia patients aged 60 years and older: Cancer and Leukemia Group B Study 9720. 
  • Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse. 
  • Essential amino acid deprivation induces monocytic differentiation of the human HL-60 myeloid leukemia cell line. 
  • Essential role of LAT in T cell development. 
  • Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia. 
  • Establishment of the DU.528 human lymphohemopoietic stem cell line. 
  • Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay. 
  • Ethylenecarbodiimide-fixed donor splenocyte infusions differentially target direct and indirect pathways of allorecognition for induction of transplant tolerance. 
  • Ethylenecarbodiimide-treated splenocytes carrying male CD4 epitopes confer histocompatibility Y chromosome antigen transplant protection by inhibiting CD154 upregulation. 
  • Evaluation of GM-CSF mouthwash for prevention of chemotherapy-induced mucositis: a randomized, double-blind, dose-ranging study. 
  • Evaluation of Residual Disease Positivity Rates in Adult Acute Lymphoblastic Leukemia Patients Treated with Asparaginase Versus Non-Asparaginase Containing Regimens 
  • Evaluation of a role for 1,25-dihydroxyvitamin D3 in the pathogenesis and treatment of X-linked hypophosphatemic rickets and osteomalacia. 
  • Evidence for an immune barrier after in utero hematopoietic-cell transplantation. 
  • Evidence of fibroblast heterogeneity and the role of fibroblast subpopulations in fibrosis. 
  • Evidence that several high-frequency human blood group antigens reside on phosphatidylinositol-linked erythrocyte membrane proteins. 
  • Ex vivo expanded peripheral blood progenitor cells provide rapid neutrophil recovery after high-dose chemotherapy in patients with breast cancer. 
  • Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. 
  • Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification. 
  • Examination of seven candidate regions for multiple sclerosis: strong evidence of linkage to chromosome 1q44. 
  • Excess diagnosis of non-Hodgkin's lymphoma during spring in the USA. 
  • Exercise training changes IL-10/TNF-alpha ratio in the skeletal muscle of post-MI rats. 
  • Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus. 
  • Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. 
  • Expression of CD44 molecules and CD44 ligands during human thymic fetal development: expression of CD44 isoforms is developmentally regulated. 
  • Expression of T-lymphoblast-encoded HLA-DR antigens on human T-B lymphoblast hybrids. 
  • Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer. 
  • Expression of differentiation antigens by hybrids of human lymphoblastoid cells. 
  • Expression of heme oxygenase-1 can determine cardiac xenograft survival. 
  • Expression of human T cell receptor-gamma delta structural forms. 
  • Expression of protooncogene c-myb in normal human hematopoietic cells. 
  • Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. 
  • Expression of the cystic fibrosis gene in adult human lung. 
  • Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells. 
  • Extensive haplotype diversity in African American mothers and their cord blood units. 
  • Extent of stimulation controls the formation of memory CD8 T cells. 
  • Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion. 
  • Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia. 
  • FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial. 
  • FGF23 induces left ventricular hypertrophy. 
  • FLT3 internal tandem duplication mutations are rare in agnogenic myeloid metaplasia. 
  • FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. 
  • FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. 
  • Factors Associated with Long-Term Risk of Relapse after Unrelated Cord Blood Transplantation in Children with Acute Lymphoblastic Leukemia in Remission. 
  • Factors associated with graft rejection after HLA-identical marrow transplantation for aplastic anaemia. 
  • Factors associated with survival in a contemporary adult sickle cell disease cohort. 
  • Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. 
  • Family-Associated Monoclonal B Lymphocytosis Is Commonly Oligoclonal and Expresses Markers Associated with Adverse Risk in CLL 
  • Family-Associated Monoclonal B Lymphocytosis Shows Differences From CLL That Suggest An Indolent Biology 
  • Family-directed umbilical cord blood banking. 
  • Fate of patients with newly diagnosed acute myeloid leukemia who fail primary induction therapy. 
  • Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers. 
  • Favorable Outcomes for Older Adolescents and Young Adults (AYA) with Acute Lymphoblastic Leukemia (ALL): Early Results of US Intergroup Trial C10403 
  • Favorable Outcomes with Fludarabine, High Dose Cytarabine and Granulocyte Colony Stimulating Factor (FLAG) As Re-Induction for Residual Acute Myeloid Leukemia on Day 14 Bone Marrow 
  • Feasibility of Allogeneic Hematopoietic Cell Transplantation Among High-Risk AML Patients in First Complete Remission: Results of the Transplant Objective from the SWOG (S1203) Randomized Phase III Study of Induction Therapy Using Standard 7+3 Therapy or Idarubicin with High-Dose Cytarabine (IA) Versus IA Plus Vorinostat 
  • Feasibility of frequent patient-reported outcome surveillance in patients undergoing hematopoietic cell transplantation. 
  • Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. 
  • Final Results of the Chrysalis Trial: A First-in-Human Phase 1/2 Dose-Escalation, Dose-Expansion Study of Gilteritinib (ASP2215) in Patients with Relapsed/ Refractory Acute Myeloid Leukemia (R/R AML) 
  • Final results of a multivariate logistic regression analysis to determine factors contributing to the risk of developing hepatic veno-occlusive disease (VOD) following treatment with gemtuzumab ozogamicin. 
  • Financial Burden and Patient-Reported Outcomes after Hematopoietic Cell Transplantation: Impact of Pre-Treatment Awareness of Transplant-Associated Costs 
  • Fingolimod Is Cytotoxic in Acute Myeloid Leukemia Independent of Additional Chemotherapeutic Agents 
  • First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients. 
  • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. 
  • Flow cytometric analysis of intercellular adhesion between B-cell precursor acute lymphoblastic leukemic cells and bone marrow stromal cells. 
  • Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor. 
  • Flow cytometric methods for prenatal and neonatal diagnosis. 
  • Flow cytometry sorting of recombinant mycobacterial species yields bacterial clones with enhanced insert expression. 
  • Fludarabine with pharmacokinetically guided IV busulfan is superior to fixed-dose delivery in pretransplant conditioning of AML/MDS patients. 
  • Fludarabine, melphalan, thiotepa and anti-thymocyte globulin conditioning for unrelated cord blood transplant. 
  • Fludarabine-based nonmyeloablative stem cell transplantation for sickle cell disease with and without renal failure: clinical outcome and pharmacokinetics. 
  • Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production. Modulation by potassium channel blockade. 
  • Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes. 
  • Fluorescent in situ hybridization in the diagnosis, prognosis, and treatment monitoring of chronic myeloid leukemia. 
  • Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. 
  • Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. 
  • Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. 
  • Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells. 
  • Forging a field: the golden age of iron biology. 
  • Four different regimens of farnesyltransferase inhibitor tipifarnib in older, untreated acute myeloid leukemia patients: North American Intergroup Phase II study SWOG S0432. 
  • Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. 
  • Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow. 
  • Frequency of MART-1/MelanA and gp100/PMel17-specific T cells in tumor metastases and cultured tumor-infiltrating lymphocytes. 
  • From genome-wide to candidate gene: an investigation of variation at the major histocompatibility complex in common bottlenose dolphins exposed to harmful algal blooms 
  • Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation. 
  • Frontline-Treatment Of Acute Lymphoblastic Leukemia (ALL) In Older Adolescents and Young Adults (AYA) Using a Pediatric Regimen Is Feasible: Toxicity Results of the Prospective US Intergroup Trial C10403 (Alliance) 
  • Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration. 
  • Function and regulation of chemoattractant receptors. 
  • Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development. 
  • Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations. 
  • Functional and numerical T cell abnormalities in chronic lymphocytic leukemia 
  • Functional association of CD7 with phosphatidylinositol 3-kinase: interaction via a YEDM motif. 
  • Functional repair of a mutant chloride channel using a trans-splicing ribozyme. 
  • Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children. 
  • Fungal infection prevention after hematopoietic cell transplantation. 
  • Further investigation of the role of factor XIII in priapism associated with SCD 
  • G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. 
  • GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL. 
  • GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer. 
  • GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo. 
  • GP120 specific cellular cytotoxicity in HIV-1 seropositive individuals. Evidence for circulating CD16+ effector cells armed in vivo with cytophilic antibody. 
  • GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain. 
  • GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression. 
  • Gamma (immune) interferon production by leukocytes from a patient with a TG cell proliferative disease. 
  • Gemtuzumab ozogamicin (Mylotarg (R)) as primary induction therapy for elderly patients with acute myeloid leukemia: A phase II trial 
  • Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. 
  • Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. 
  • Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity. 
  • Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. 
  • Gene segment selection in V(D)J recombination: accessibility and beyond. 
  • Gene therapies for hemophilia hit the mark in clinical trials 
  • Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. 
  • Gene therapy for human SCID: dreams become reality. 
  • Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model. 
  • Gene-centric association study of acute chest syndrome and painful crisis in sickle cell disease patients. 
  • Generation of mucosal anti-human immunodeficiency virus type 1 T-cell responses by recombinant Mycobacterium smegmatis. 
  • Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. 
  • Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. 
  • Genetic analysis of susceptibility to Chlamydia trachomatis in mouse. 
  • Genetic basis of murine responses to hyperoxia-induced lung injury. 
  • Genetic convergence of rare lymphomas. 
  • Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila. 
  • Genetic engineering of a suboptimal islet graft with A20 preserves beta cell mass and function. 
  • Genetic engineering of murine CD8+ and CD4+ T cells for preclinical adoptive immunotherapy studies. 
  • Genetic epidemiology of the susceptibility to leprosy. 
  • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. 
  • Genetic manipulation of primitive leukemic and normal hematopoietic cells using a novel method of adenovirus-mediated gene transfer. 
  • Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. 
  • Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism. 
  • Genetic therapies for cardiovascular diseases. 
  • Genetic-based dosing in orthopedic patients beginning warfarin therapy. 
  • Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. 
  • Genome-Wide Analysis of Microdeletions and Identification of NF1 Inactivation in Acute Myelogenous Leukemia. 
  • Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement. 
  • Genome-wide association for smoking cessation success: participants in a trial with adjunctive denicotinized cigarettes. 
  • Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. 
  • Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL. 
  • Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia. 
  • Genome-wide association study of severity in multiple sclerosis. 
  • Genome-wide study of methotrexate clearance replicates SLCO1B1. 
  • Genomic profiling of chronic lymphocytic leukemia identifies novel genetic subtypes. 
  • Genomic signatures to guide the use of chemotherapeutics. 
  • Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells. 
  • Genotype-phenotype correlation in MYH9-related thrombocytopenia. 
  • Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination. 
  • Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells. 
  • Germinal center responses to complex antigens 
  • Germline sequences of V(H)7183 gene family members in C57BL/6 mice demonstrate natural selection of particular sequences during recent evolution. 
  • Getting biological about the genetics of diabetes. 
  • Ghrelin and hypothalamic development: too little and too much of a good thing. 
  • Glioblastoma multiforme: an emerging paradigm of anti-VEGF therapy. 
  • Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. 
  • Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis. 
  • Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. 
  • Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. 
  • Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. 
  • Glutathione peroxidase protein. Absence in selenium deficiency states and correlation with enzymatic activity. 
  • Glycosyl-phosphatidylinositol anchor synthesis in paroxysmal nocturnal hemoglobinuria: partial or complete defect in an early step. 
  • Gpr124 is essential for blood-brain barrier integrity in central nervous system disease. 
  • Gq signaling causes glomerular injury by activating TRPC6. 
  • Graft-versus-host disease prophylaxis with methotrexate/cyclosporine in children with severe aplastic anemia treated with cyclophosphamide and HLA-identical marrow grafts. 
  • Grafted cerebellar cells in a mouse model of hereditary ataxia express IGF-I system genes and partially restore behavioral function. 
  • Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN). 
  • Granulocyte-colony stimulating factor (filgrastim) accelerates granulocyte recovery after intensive postremission chemotherapy for acute myeloid leukemia with aziridinyl benzoquinone and mitoxantrone: Cancer and Leukemia Group B study 9022. 
  • Granulocyte-macrophage colony-stimulating factor as adjunct therapy in relapsed lymphoid malignancy: implications for economic analyses of phase III clinical trials. 
  • Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. 
  • Great expectations. 
  • Growth hormone accelerates immune recovery following allogeneic T-cell-depleted bone marrow transplantation in mice. 
  • Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors. 
  • Gut microbes out of control in HIV infection. 
  • H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury. 
  • HCT outcomes: a new tool? 
  • HDAC3 sets the timer on muscle fuel switching. 
  • HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia. 
  • HIGH-THROUGHPUT RNA INTERFERENCE SCREENING IDENTIFIES SYNTHETIC LETHALITY BETWEEN ONCOGENIC KRAS DEPENDENCY AND SUPPRESSION OF STK33 
  • HIV antibodies for treatment of HIV infection. 
  • HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition. 
  • HIV vaccine development at Duke University Medical Center. 
  • HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism. 
  • HIV-1 GP120-mediated immune suppression and lymphocyte destruction in the absence of viral infection. 
  • HIV-1 Nef protein: An invitation to a kill. 
  • HIV-1 Neutralizing Antibodies: Understanding Nature's Pathways 
  • HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria. 
  • HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life. 
  • HIV-1 infection: fooling the gatekeeper. 
  • HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes. 
  • HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound. 
  • HIV-1: nature's master of disguise. 
  • HIV-Host Interactions: Implications for Vaccine Design. 
  • HIV-specific humoral responses benefit from stronger prime in phase Ib clinical trial. 
  • HLA class II molecules on monocytes regulate T cell proliferation through physical interaction in the CD3 activation pathway. 
  • HLA-identical marrow transplantation during accelerated-phase chronic myelogenous leukemia: analysis of survival and remission duration. 
  • Haploidentical hematopoietic cell transplantation. 
  • Happy birthday JCI. 
  • Harboring of particulate allergens within secretory compartments by mast cells following IgE/FcepsilonRI-lipid raft-mediated phagocytosis. 
  • Healing of bone disease in X-linked hypophosphatemic rickets/osteomalacia. Induction and maintenance with phosphorus and calcitriol. 
  • Health Care Utilization and End of Life Care for Older Patients with Acute Myeloid Leukemia Receiving Supportive Care Alone 
  • Heart and lung disease in engineered mice. 
  • Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivity. 
  • Heavy LIFting: tumor promotion and radioresistance in NPC. 
  • Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis. 
  • Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. 
  • Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. 
  • Hematopoietic Stem Cell Transplantation Activity in Pediatric Cancer between 2008 and 2014 in the United States: A Center for International Blood and Marrow Transplant Research Report. 
  • Hematopoietic Stem Cell Transplantation in ADA2 Deficiency: Early Restoration of ADA2 Enzyme Activity and Disease Relapse upon Drop of Donor Chimerism. 
  • Hematopoietic cell transplant comorbidity index is predictive of survival after autologous hematopoietic cell transplantation in multiple myeloma. 
  • Hematopoietic cell transplantation with cord blood for cure of HIV infections. 
  • Hematopoietic stem cell transplantation rescues the hematological, immunological, and vascular phenotype in DADA2. 
  • Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production 
  • Hemoglobin C associated with protection from severe malaria in the Dogon of Mali, a West African population with a low prevalence of hemoglobin S. 
  • Hemoglobin S-nitrosylation plays an essential role in cardioprotection. 
  • Hemorrhagic cystitis after allogeneic bone marrow transplantation in children: clinical characteristics and outcome. 
  • Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplants is the complex result of BK virus infection, preparative regimen intensity and donor type. 
  • Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation. 
  • Heparin cofactor II-proteinase reaction products exhibit neutrophil chemoattractant activity. 
  • Heparin modifies the immunogenicity of positively charged proteins. 
  • Heparin-induced thrombocytopenia. 
  • Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. 
  • Hepatic iron concentration does not influence response to therapy with interferon plus ribavirin in chronic HCV infection. 
  • Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway. 
  • Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3-dependent induction of IDO. 
  • Hepatic veno-occlusive disease following stem cell transplantation: incidence, clinical course, and outcome. 
  • Hepatic β-arrestin 2 is essential for maintaining euglycemia. 
  • Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling. 
  • Hepatosplenic T-cell lymphoma with blastoid morphology in a patient with Crohn disease. 
  • Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. 
  • Herpes simplex virus (HSV)-mediated ICAM-1 gene transfer abrogates tumorigenicity and induces anti-tumor immunity. 
  • Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin. 
  • High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques. 
  • High Variability in the Reported Management of Hepatic Veno-Occlusive Disease in Children after Hematopoietic Stem Cell Transplantation. 
  • High dose CHOP: a phase II study of initial treatment in aggressive non-Hodgkin lymphoma. Cancer and Leukemia Group B 9351. 
  • High dose cyclophosphamide plus recombinant human granulocyte-colony stimulating factor (rhG-CSF) in the treatment of follicular, low grade non-Hodgkin's lymphoma: CALGB 9150. 
  • High dose factor VIIa improves clot structure and stability in a model of haemophilia B. 
  • High dose intravenous immunoglobulin does not affect complement-bacteria interactions. 
  • High expression of nucleoside transporter protein hENT1 in Reed-Sternberg cells is associated with treatment failure in relapsed/refractory Hodgkin lymphoma patients treated with gemcitabine, vinorelbine and liposomal doxorubicin - a CALGB 59804 correlative study. 
  • High frequency of immunophenotype changes in acute myeloid leukemia at relapse: implications for residual disease detection (Cancer and Leukemia Group B Study 8361). 
  • High incidence of antibodies to protamine and protamine/heparin complexes in patients undergoing cardiopulmonary bypass. 
  • High level expression of CD43 inhibits T cell receptor/CD3-mediated apoptosis. 
  • High-dose chemotherapy with AHPCS for the treatment of breast cancer. The University of Colorado results. 
  • High-dose chemotherapy with autologous peripheral blood progenitor cell support for primary breast cancer in patients with 4-9 involved axillary lymph nodes. 
  • High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study. 
  • High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis. 
  • High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes. 
  • High-dose infusional gemcitabine combined with busulfan and melphalan with autologous stem-cell transplantation in patients with refractory lymphoid malignancies. 
  • High-dose therapy with autologous hematopoietic cell support as salvage treatment for patients with breast cancer who have relapsed after previous high-dose chemotherapy. 
  • High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses. 
  • Histopathologic changes in anti-angiotensin II type 1 receptor antibody-positive kidney transplant recipients with acute rejection and no donor specific HLA antibodies. 
  • Hitting the reset button for immune tolerance. 
  • Holding the Inflammatory System in Check: TLRs and NLRs. 
  • Homeostatic control of lymphocyte survival: potential origins and implications. 
  • Hormonal activation of adenylate cyclase in macrophage membranes is regulated by guanine nucleotides. 
  • Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins. 
  • Host controls of HIV broadly neutralizing antibody development. 
  • Host defenses against cryptococcosis. 
  • Host-microbe interactions in the developing zebrafish. 
  • Hostile takeover: fungal protein promotes host cell invasion. 
  • How I treat ADA deficiency. 
  • How I treat catastrophic thrombotic syndromes. 
  • How I treat sinusoidal obstruction syndrome. 
  • How I treat thrombocytopenia in pregnancy. 
  • How I use fibrinogen replacement therapy in acquired bleeding. 
  • How do plants achieve immunity? Defence without specialized immune cells. 
  • How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways. 
  • How irritation: The role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways 
  • How mast cells make decisions. 
  • How much vitamin D should I take? 
  • Human B cell alloantigens: expression of MB and MT determinants. 
  • Human B cell alloantigens; alpha subunit variability. 
  • Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance. 
  • Human IFN-gamma production is inhibited by a synthetic peptide homologous to retroviral envelope protein. 
  • Human IL-1 beta processing and secretion in recombinant baculovirus-infected Sf9 cells is blocked by the cowpox virus serpin crmA. 
  • Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression. 
  • Human Responses to Influenza Vaccination Show Seroconversion Signatures and Convergent Antibody Rearrangements 
  • Human Stem Cell Transplantation 
  • Human T cell receptor-gamma and -delta chain pairing analyzed by transfection of a T cell receptor-delta negative mutant cell line. 
  • Human T cell reconstitution in DiGeorge syndrome and HIV-1 infection. 
  • Human T-cell leukemia/lymphoma virus: studies of host-virus interaction. 
  • Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. 
  • Human cord blood derived CD14 cell therapy provides neuroprotection in aquired brain injury 
  • Human erythrocyte acetylcholinesterase bears the Yta blood group antigen and is reduced or absent in the Yt(a-b-) phenotype. 
  • Human erythrocyte antigens: II. The In(Lu) gene regulates expression of an antigen on an 80-kilodalton protein of human erythrocytes. 
  • Human immunodeficiency virus-1 disease progression in hemophiliacs. 
  • Human lymphocyte proliferation responses following primary immunization with rabies vaccine as neoantigen. 
  • Human medullary thymocyte p80 antigen and In(Lu)-related p80 antigen reside on the same protein. 
  • Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. 
  • Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. 
  • Human natural killer cells analyzed by B73.1, a monoclonal antibody blocking Fc receptor functions. I. Characterization of the lymphocyte subset reactive with B73.1. 
  • Human neutrophil dysfunction with giant granules and defective activation of the respiratory burst. 
  • Human placental cytotrophoblasts attract monocytes and CD56(bright) natural killer cells via the actions of monocyte inflammatory protein 1alpha. 
  • Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. 
  • Human platelets exhibit chemotaxis using functional N-formyl peptide receptors. 
  • Human postnatal CD4- CD8- CD3- thymic T cell precursors differentiate in vitro into T cell receptor delta-bearing cells. 
  • Human retrovirus-related synthetic peptides inhibit T lymphocyte proliferation. 
  • Human secretory immunoglobulin A may contribute to biofilm formation in the gut. 
  • Human thymic epithelial cells function as accessory cells for autologous mature thymocyte activation. 
  • Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF, and leukemia inhibitory factor. 
  • Human thymic epithelial cells produce granulocyte and macrophage colony-stimulating factors. 
  • Human thymic epithelial cells produce interleukin 1. 
  • Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem. 
  • Humoral autoimmunity to basement membrane antigens is regulated in C57BL/6 and MRL/MpJ mice transgenic for anti-laminin Ig receptors. 
  • Humoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses. 
  • Humoral immunostimulation. IV. Role of complement. 
  • Hyper IgM Syndrome: a Report from the USIDNET Registry. 
  • Hyper IgM syndrome associated with defective CD40-mediated B cell activation. 
  • Hyperspectral imaging system using acousto-optic tunable filter for flow cytometry applications. 
  • Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH. 
  • ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration. 
  • ICON: the early diagnosis of congenital immunodeficiencies. 
  • IFATS collection: Adipose-derived stromal cells improve the foreign body response. 
  • IFN-gamma dictates allograft fate via opposing effects on the graft and on recipient CD8 T cell responses. 
  • IFN-gamma induction of p21(WAF1) is required for cell cycle inhibition and suppression of apoptosis. 
  • IL-1 is an effective adjuvant for mucosal and systemic immune responses when coadministered with protein immunogens. 
  • IL-10 stimulatory effects on human NK cells explored by gene profile analysis. 
  • IL-10+ regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation. 
  • IL-15 regulates homeostasis and terminal maturation of NKT cells. 
  • IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection. 
  • IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils. 
  • IL-4-STAT6 signal transduction-dependent induction of the clinical phase of Sjögren's syndrome-like disease of the nonobese diabetic mouse. 
  • IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells. 
  • IL-7 enhancement of antigen-driven activation/expansion of HIV-1-specific cytotoxic T lymphocyte precursors (CTLp). 
  • IL-7 enhances the survival and maintains the size of naive T cells. 
  • IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival. 
  • IMGN779, a Next-Generation CD33-Targeting Antibody-Drug Conjugate (ADC) Demonstrates Initial Antileukemia Activity in Patients with Relapsed or Refractory Acute Myeloid Leukemia 
  • INTER-V-H-GENE-FAMILY SHARED IDIOTYPE ON ACQUIRED IMMUNODEFICIENCY SYNDROME-ASSOCIATED LYMPHOMAS 
  • ISO: a critical evaluation of the role of peptides in heat shock/chaperone protein-mediated tumor rejection. 
  • ITAM-containing adaptors regulate NKG2D-mediated cytotoxicity in human NK cells 
  • Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors. 
  • Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity. 
  • Id3 and Id2 act as a dual safety mechanism in regulating the development and population size of innate-like γδ T cells. 
  • Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans. 
  • Identification of a B cell signature associated with renal transplant tolerance in humans. 
  • Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. 
  • Identification of a Costimulation Blockade Resistant Mechanism of Bone Marrow Allograft Rejection Induced by Infection with a Murine EBV Homologue. 
  • Identification of a second class of IgG Fc receptors on human neutrophils. A 40 kilodalton molecule also found on eosinophils. 
  • Identification of a tissue-specific, C/EBPβ-dependent pathway of differentiation for murine peritoneal macrophages. 
  • Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies. 
  • Identification of beta-adrenergic receptors in human lymphocytes by (-) (3H) alprenolol binding. 
  • Identification of human erythrocyte blood group antigens on decay-accelerating factor (DAF) and an erythrocyte phenotype negative for DAF. 
  • Identification of human erythrocyte blood group antigens on the C3b/C4b receptor. 
  • Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands. 
  • Identification of recombinant antibodies against multiple distinct toll-like receptors by homolog mining a single immune scFv phage library. 
  • Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies. 
  • Identification of the human NHE-1 form of Na(+)-H+ exchanger in rabbit renal brush border membranes. 
  • Identifying local and descending inputs for primary sensory neurons. 
  • Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death. 
  • IgG antibodies from patients with bullous pemphigoid bind to localized epitopes on synthetic peptides encoded by bullous pemphigoid antigen cDNA. 
  • Image Segmentation and Dynamic Lineage Analysis in Single-Cell Fluorescence Microscopy 
  • Image segmentation and dynamic lineage analysis in single-cell fluorescence microscopy. 
  • Immune containment and consequences of measles virus infection in healthy and immunocompromised individuals. 
  • Immune mechanisms in inflammatory and degenerative eye disease. 
  • Immune reconstitution after unrelated cord blood transplantation. 
  • Immune reconstitution and survival of 100 SCID patients post-hematopoietic cell transplant: a PIDTC natural history study. 
  • Immune recovery in adult patients after myeloablative dual umbilical cord blood, matched sibling, and matched unrelated donor hematopoietic cell transplantation. 
  • Immune regulation by glucocorticoids. 
  • Immune response of chimpanzee to purified melanoma 250 kilodalton tumor-associated antigen. 
  • Immune response to influenza vaccination in the elderly is altered by chronic medication use. 
  • Immune-related Neurological Symptoms in an Adolescent Patient Receiving the Checkpoint Inhibitor Nivolumab. 
  • Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle. 
  • Immunization of normal human splenocytes in vitro to produce human monoclonal antibodies to cellular antigens. 
  • Immunoblot analysis of anti-Ureaplasma urealyticum antibody in pregnant women and newborn infants. 
  • Immunodeficiencies. 
  • Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice. 
  • Immunodominant sites of human T cell lymphotropic virus type 1 envelope protein for murine helper T cells. 
  • Immunogenetics and immunology in transplantation. 
  • Immunogenetics and transplantation. 
  • Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies. 
  • Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion. 
  • Immunoinhibition of intracellular protein digestion in macrophages. 
  • Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies. 
  • Immunologic characterization of CD7-deficient mice. 
  • Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy. 
  • Immunologic reconstitution during PEG-ADA therapy in an unusual mosaic ADA deficient patient. 
  • Immunomodulation of experimental autoimmune encephalomyelitis by helminth ova immunization. 
  • Immunosenescence and germinal center reaction. 
  • Immunosuppressive activity of the retroviral envelope protein P 15E and its possible relationship to neoplasia. 
  • Immunosuppressive retroviral peptides: immunopathological implications for immunosuppressive influences of retroviral infections. 
  • Immunotherapy of malignant brain tumors. 
  • Immunotherapy of type 1 diabetes: where are we and where should we be going? 
  • Impact of Available Therapies on Survival of Very Elderly Myelodysplastic Syndrome (MDS) Patients (Age above 75 yrs) 
  • Impact of Polymorphic Variations of Gemcitabine Metabolism, DNA Damage Repair, and Drug-Resistance Genes on the Effect of High-Dose Chemotherapy for Relapsed or Refractory Lymphoid Malignancies. 
  • Impact of Poxvirus Vector Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques. 
  • Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT. 
  • Impact of post-transplantation maintenance therapy on health-related quality of life in patients with multiple myeloma: data from the Connect® MM Registry. 
  • Impact of prior imatinib mesylate on the outcome of hematopoietic cell transplantation for chronic myeloid leukemia. 
  • Impact of pronase on flow cytometric crossmatch outcome. 
  • Impaired formation of beta-adrenergic receptor-nucleotide regulatory protein complexes in pseudohypoparathyroidism. 
  • Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47). 
  • Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria. 
  • Impairment of filgrastim-induced stem cell mobilization after prior lenalidomide in patients with multiple myeloma. 
  • Implementation of Good Clinical Laboratory Practice (GCLP) guidelines within the External Quality Assurance Program Oversight Laboratory (EQAPOL). 
  • Implementation of multidisciplinary care reduces maternal mortality in women with sickle cell disease living in low-resource setting. 
  • Important impact of gingival and periodontal conditions on outcomes in SCT recipients. 
  • Improved Prognostic Significance of Genomic and Transcriptional Biomarkers By Examining Enriched Populations of AML Blasts: A SWOG Report 
  • Improved Survival in Patients with First Relapsed or Refractory Acute Myeloid Leukemia (AML) Treated with Vosaroxin Plus Cytarabine Versus Placebo Plus Cytarabine: Results of a Phase 3 Double-Blind Randomized Controlled Multinational Study (VALOR) 
  • Improved detection of diffuse large B-cell lymphoma by flow cytometric immunophenotyping-Effect of tissue disaggregation method. 
  • Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01. 
  • Improved outcome in central nervous system aspergillosis, using voriconazole treatment. 
  • Improvements in digital vasculature observed using micro magnetic resonance angiography after high-dose immunosuppression for severe systemic sclerosis. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance. 
  • In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. 
  • In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia. 
  • In vitro culture of human peripheral blood monocytes induces hyaluronan binding and up-regulates monocyte variant CD44 isoform expression. 
  • In vitro desensitization of beta adrenergic receptors in human neutrophils. Attenuation by corticosteroids. 
  • In vitro function of indium-111 oxine-labeled human monocytes. 
  • In vitro growth and phenotypic characterization of mesodermal-derived and epithelial components of normal and abnormal human thymus. 
  • In vitro priming and expansion of cytomegalovirus-specific Th1 and Tc1 T cells from naive cord blood lymphocytes. 
  • In vivo T cell costimulation blockade with abatacept for acute graft-versus-host disease prevention: a first-in-disease trial. 
  • In vivo cytotoxic T lymphocyte induction with soluble proteins administered in liposomes. 
  • Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. 
  • Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. 
  • Incidence of tumor-cell contamination in leukapheresis products of breast cancer patients mobilized with stem cell factor and granulocyte colony-stimulating factor (G-CSF) or with G-CSF alone. 
  • Incidence, risk factors, and mortality from pneumonia developing late after hematopoietic stem cell transplantation. 
  • Increase in TCR gamma delta T lymphocytes in synovia from rheumatoid arthritis patients with active synovitis. 
  • Increased IL-4 production and attenuated proliferative and pro-inflammatory responses of splenocytes from wild-caught rats (Rattus norvegicus). 
  • Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. 
  • Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6. 
  • Increased expression of blood mononuclear cell nitric oxide synthase type 2 in rheumatoid arthritis patients. 
  • Increased glutamine catabolism mediates bone anabolism in response to WNT signaling. 
  • Increased levels of IgE and autoreactive, polyreactive IgG in wild rodents: implications for the hygiene hypothesis. 
  • Increased prevalence of potential right-to-left shunting in children with sickle cell anaemia and stroke. 
  • Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma. 
  • Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation. 
  • Increasing chimerism after allogeneic stem cell transplantation is associated with longer survival time. 
  • Increasing incidence of chronic graft-versus-host disease in allogeneic transplantation: a report from the Center for International Blood and Marrow Transplant Research. 
  • Increasing use of allogeneic hematopoietic cell transplantation in patients aged 70 years and older in the United States. 
  • Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. 
  • Induced sensitization of tumor stroma leads to eradication of established cancer by T cells 
  • Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. 
  • Induction of CD56 and TCR-independent activation of T cells with aging. 
  • Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses. 
  • Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux. 
  • Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells. 
  • Induction of cytotoxic T lymphocytes with dendritic cells transfected with human papillomavirus E6 and E7 RNA: implications for cervical cancer immunotherapy. 
  • Induction of immunity to human immunodeficiency virus type-1 by vaccination. 
  • Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. 
  • Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA. 
  • Infectious morbidity in long-term survivors of allogeneic marrow transplantation is associated with low CD4 T cell counts 
  • Inflammasome, Inflammation, and Tissue Homeostasis 
  • Inflammasomes are important mediators of prostatic inflammation associated with BPH 
  • Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. 
  • Influence of heavy chain constant regions on antigen binding and HIV-1 neutralization by a human monoclonal antibody. 
  • Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. 
  • Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation. 
  • Inherited human complement C5 deficiency. Nonsense mutations in exons 1 (Gln1 to Stop) and 36 (Arg1458 to Stop) and compound heterozygosity in three African-American families. 
  • Inhibition of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-ALL after blocking remote 3'-BCL11B enhancer sequences with matching DNA oligos reveals coregulation by PU.1 and HMGA1. 
  • Inhibition of human natural killer cell activity by a synthetic peptide homologous to a conserved region in the retroviral protein, p15E. 
  • Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade. 
  • Inhibition of murine cytotoxic T lymphocyte activity by a synthetic retroviral peptide and abrogation of this activity by IL. 
  • Inhibition of nitric oxide synthase (NOS) 1, NOS2, and NOS3 enzymatic activities by vitamin B-12 and related corrins: Biochemical and molecular modeling studies 
  • Inhibition of protein kinase C by a peptide conjugate homologous to a domain of the retroviral protein p15E. 
  • Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure. 
  • Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma. 
  • Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth. 
  • Inhibition of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) messenger RNA (mRNA) expression in HL-60 leukemia cells by pentoxifylline and dexamethasone: dissociation of acivicin-induced TNF-alpha and IL-1 beta mRNA expression from acivicin-induced monocytoid differentiation. 
  • Inhibitors of histone deacetylases promote hematopoietic stem cell self-renewal. 
  • Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease. 
  • Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. 
  • Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. 
  • Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. 
  • Innate Antiviral Immunity in the Skin. 
  • Innate Immune Cell Recovery Is Positively Regulated by NLRP12 during Emergency Hematopoiesis 
  • Innate Immune Cell Recovery Is Positively Regulated by NLRP12 during Emergency Hematopoiesis. 
  • Innate immunity against vaccinia virus is mediated by TLR2 and requires TLR-independent production of IFN-beta. 
  • Innate immunity and its regulation by mast cells. 
  • Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma. 
  • Insight into the mechanism of asparaginase-induced depletion of antithrombin III in treatment of childhood acute lymphoblastic leukemia. 
  • Insights into antiviral innate immunity revealed by studying hepatitis C virus. 
  • Inspiring the next generation of physician-scientists. 
  • Insurance Design and Out-of-Pocket (OOP) Costs: a Comparison of Oral and Intravenous (IV) Treatment Plans for Chronic Lymphocytic Leukemia (CLL) in the Era of the Affordable Care Act (ACA) 
  • Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. 
  • Integrin beta 1 regulates phagosome maturation in macrophages through Rac expression. 
  • Intensive chemotherapy for progressive chronic lymphocytic leukemia administered early after a nonmyeloablative allograft. 
  • Intensive high-dose asparaginase consolidation improves survival for pediatric patients with T cell acute lymphoblastic leukemia and advanced stage lymphoblastic lymphoma: a Pediatric Oncology Group study. 
  • Intercellular adhesion molecule-1 deficiency attenuates the development of skin fibrosis in tight-skin mice. 
  • Interferon (IFN)-alpha activation of human blood mononuclear cells in vitro and in vivo for nitric oxide synthase (NOS) type 2 mRNA and protein expression: possible relationship of induced NOS2 to the anti-hepatitis C effects of IFN-alpha in vivo. 
  • Interferon-gamma for delayed pulmonary toxicity syndrome resistant to steroids. 
  • Intergroup LEAP trial (S1612): A randomized phase 2/3 platform trial to test novel therapeutics in medically less fit older adults with acute myeloid leukemia. 
  • Interim Analysis of a Phase 1 Trial of SGN-CD33A in Patients with CD33-Positive Acute Myeloid Leukemia (AML) 
  • Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. 
  • Interleukin-2 reverses CD8(+) T cell exhaustion in clinical malignant pleural effusion of lung cancer. 
  • Interleukin-3-induced activation of the JAK/STAT pathway is prolonged by proteasome inhibitors. 
  • Interleukin-6 induces hepcidin expression through STAT3. 
  • Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. 
  • Internalization of FimH+ Escherichia coli by the human mast cell line (HMC-1 5C6) involves protein kinase C. 
  • Interplay between DNA tumor viruses and the host DNA damage response. 
  • Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. 
  • Intestinal Microbiota Injury during Allo-Hct is Generalizable across Transplantation Centers and is Associated with Increased Mortality, Broad-Spectrum Antibiotics, and Decreased Calorie Intake 
  • Intracellular innate immune cascades and interferon defenses that control hepatitis C virus. 
  • Intracellular osteopontin (iOPN) and immunity. 
  • Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy. 
  • Intranasal immunization with CTL epitope peptides from HIV-1 or ovalbumin and the mucosal adjuvant cholera toxin induces peptide-specific CTLs and protection against tumor development in vivo. 
  • Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA. 
  • Intrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion. 
  • Intravenous BU plus Mel: an effective, chemotherapy-only transplant conditioning regimen in patients with ALL. 
  • Intravenous Busulfan Compared with Total Body Irradiation Pretransplant Conditioning for Adults with Acute Lymphoblastic Leukemia 
  • Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia. 
  • Intravenous busulfan in pretransplant chemotherapy: bioavailability and patient benefit. 
  • Intravenous busulfan plus melphalan is a highly effective, well-tolerated preparative regimen for autologous stem cell transplantation in patients with advanced lymphoid malignancies. 
  • Intravenous immunoglobulin therapy induces neutrophil apoptosis in Kawasaki disease. 
  • Intravenous versus oral busulfan as part of a busulfan/cyclophosphamide preparative regimen for allogeneic hematopoietic stem cell transplantation: decreased incidence of hepatic venoocclusive disease (HVOD), HVOD-related mortality, and overall 100-day mortality. 
  • Intrinsic IL-21 signaling is critical for CD8 T cell survival and memory formation in response to vaccinia viral infection. 
  • Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis. 
  • Intrinsic differences in L-selectin expression levels affect T and B lymphocyte subset-specific recirculation pathways. 
  • Introduction of Robert J. Lefkowitz. 
  • Inverse correlation between cerebral blood flow measured by continuous arterial spin-labeling (CASL) MRI and neurocognitive function in children with sickle cell anemia (SCA). 
  • Inverse correlation of maturity and antibacterial activity in human dendritic cells. 
  • Inverse relationship of serum albumin to the risk of venous thromboembolism among acutely ill hospitalized patients: Analysis from the APEX trial. 
  • Investigation of HIFU-induced anti-tumor immunity in a murine tumor model. 
  • Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. 
  • Is RNA interference a physiologically relevant innate antiviral immune response in mammals? 
  • Is RNA interference involved in intrinsic antiviral immunity in mammals? 
  • Islet cell transplantation for the treatment of diabetes mellitus. 
  • Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells. 
  • Isohemagglutinins and xenoreactive antibodies: members of a distinct family of natural antibodies. 
  • Isolation and expansion of oligodendrocyte progenitor cells from cryopreserved human umbilical cord blood. 
  • Isolation and generation of human dendritic cells. 
  • Isolation of microarray-quality RNA from primary human cells after intracellular immunostaining and fluorescence-activated cell sorting 
  • Isolation of the JMH antigen on a novel phosphatidylinositol-linked human membrane protein. 
  • It infects me, it infects me not: phenotypic switching in the fungal pathogen Cryptococcus neoformans. 
  • Ivosidenib (AG-120) in Mutant IDH1 AML and Advanced Hematologic Malignancies: Results of a Phase 1 Dose Escalation and Expansion Study 
  • JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma. 
  • JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. 
  • Jak3 and the pathogenesis of severe combined immunodeficiency. 
  • Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation. 
  • John F. Enders and measles virus vaccine--a reminiscence. 
  • KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. 
  • KIR genotypic diversity can track ancestries in heterogeneous populations: a potential confounder for disease association studies. 
  • Kappa editing rescues autoreactive B cells destined for deletion in mice transgenic for a dual specific anti-laminin Ig. 
  • Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. 
  • Ki67 and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: a Cancer and Leukemia Group B 59909 correlative science study. 
  • Kidney α-intercalated cells and lipocalin 2: defending the urinary tract. 
  • Knotty Zika Virus Blocks Exonuclease to Produce Subgenomic Flaviviral RNAs. 
  • Kruppel-like factor 15 is critical for vascular inflammation. 
  • Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis. 
  • L- and P-selectins, but not CD49d (VLA-4) integrins, mediate monocyte initial attachment to TNF-alpha-activated vascular endothelium under flow in vitro. 
  • L-carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia. 
  • L-selectin (CD62L) blockade does not impair peritoneal neutrophil emigration or subcutaneous host defense to bacteria in rabbits. 
  • L-selectin and beta7 integrin synergistically mediate lymphocyte migration to mesenteric lymph nodes. 
  • L-selectin binds to P-selectin glycoprotein ligand-1 on leukocytes: interactions between the lectin, epidermal growth factor, and consensus repeat domains of the selectins determine ligand binding specificity. 
  • L-selectin is involved in lymphocyte migration to sites of inflammation in the skin: delayed rejection of allografts in L-selectin-deficient mice. 
  • L-selectin is not required for T cell-mediated autoimmune diabetes. 
  • L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity. 
  • L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes. 
  • L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites. 
  • LAB: a new membrane-associated adaptor molecule in B cell activation. 
  • LAT is essential for Fc(epsilon)RI-mediated mast cell activation. 
  • LFA-1 blockade induces effector and regulatory T-cell enrichment in lymph nodes and synergizes with CTLA-4Ig to inhibit effector function. 
  • LFA-1-specific therapy prolongs allograft survival in rhesus macaques. 
  • LMP2 expression and proteasome activity in NOD mice. 
  • LMP2 expression and proteasome activity in NOD mice. 
  • Lack of protease inhibitor resistance following treatment failure--too good to be true? 
  • Large volume ex vivo expansion of CD34-positive hematopoietic progenitor cells for transplantation. 
  • Late Effects after Umbilical Cord Blood Transplantation in Very Young Children after Busulfan-Based, Myeloablative Conditioning. 
  • Late Gastrointestinal Complications of Allogeneic Hematopoietic Stem Cell Transplantation in Adults. 
  • Late cardiovascular morbidity and mortality following pediatric allogeneic hematopoietic cell transplantation. 
  • Late effects in patients with Fanconi anemia following allogeneic hematopoietic stem cell transplantation from alternative donors. 
  • Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells. 
  • Leading a sheltered life: intracellular pathogens and maintenance of vacuolar compartments. 
  • Lentiviral vector integration in the human genome induces alternative splicing and generates aberrant transcripts 
  • Leptin directly promotes T-cell glycolytic metabolism to drive effector T-cell differentiation in a mouse model of autoimmunity. 
  • Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy. 
  • Lessons from babies: inducing HIV-1 broadly neutralizing antibodies. 
  • Lessons learned from HIV-1 vaccine trials: new priorities and directions. 
  • Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy. 
  • Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy. 
  • Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion. 
  • Leukocyte migration is regulated by L-selectin endoproteolytic release. 
  • Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs. 
  • Level of tear cytokines in population-level participants and correlation with clinical features. 
  • Levels of Foxp3 in regulatory T cells reflect their functional status in transplantation. 
  • Liberation of ATP secondary to hemolysis is not mutually exclusive of regulated export. 
  • Ligand binding to the LFA-3 cell adhesion molecule induces IL-1 production by human thymic epithelial cells. 
  • Ligation of MHC class I and class II molecules can lead to heterologous desensitization of signal transduction pathways that regulate homotypic adhesion in human lymphocytes. 
  • Ligation of cell surface-associated glucose-regulated protein 78 by receptor-recognized forms of alpha 2-macroglobulin: activation of p21-activated protein kinase-2-dependent signaling in murine peritoneal macrophages. 
  • Light scattering by polymorphonuclear leukocytes stimulated to aggregate under various pharmacologic conditions. 
  • Lipopolysaccharide-induced expression of TRAIL promotes dendritic cell differentiation 
  • Liver X receptors alpha and beta regulate renin expression in vivo. 
  • Localization of collagenase mRNA in rheumatoid arthritis synovium by in situ hybridization histochemistry. 
  • Localization of the cystic fibrosis transmembrane conductance regulator in pancreas. 
  • Location, location, location: regional immune mechanisms critically influence rejection. 
  • Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation. 
  • Long-Term Functional Outcomes after Hematopoietic Stem Cell Transplant for Early Infantile Krabbe Disease. 
  • Long-Term Outcomes after Treatment with Clofarabine ± Fludarabine with Once-Daily Intravenous Busulfan as Pretransplant Conditioning Therapy for Advanced Myeloid Leukemia and Myelodysplastic Syndrome. 
  • Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection. 
  • Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID). 
  • Long-term follow-up of allogeneic bone marrow recipients for Philadelphia chromosome-positive acute lymphoblastic leukemia. 
  • Long-term follow-up of allogeneic hematopoietic stem cell transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: impact of tyrosine kinase inhibitors on treatment outcomes. 
  • Long-term health-related outcomes in survivors of childhood cancer treated with HSCT versus conventional therapy: a report from the Bone Marrow Transplant Survivor Study (BMTSS) and Childhood Cancer Survivor Study (CCSS). 
  • Long-term outcome of Hurler syndrome patients after hematopoietic cell transplantation: an international multicenter study. 
  • Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep. 
  • Long-term results of Dana-Farber Cancer Institute ALL Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1985-2000). 
  • Long-term survival and late deaths after hematopoietic cell transplantation for primary immunodeficiency diseases and inborn errors of metabolism. 
  • Long-term tolerance to allogeneic thymus transplants in complete DiGeorge anomaly. 
  • Longitudinal analysis of T-cell receptor variable beta chain repertoire in patients with acute graft-versus-host disease after allogeneic stem cell transplantation. 
  • Loss of the mismatched human leukocyte antigen haplotype in two acute myelogenous leukemia relapses after haploidentical bone marrow transplantation with post-transplantation cyclophosphamide. 
  • Low incidence of Epstein-Barr virus-associated posttransplantation lymphoproliferative disorders in 272 unrelated-donor umbilical cord blood transplant recipients. 
  • Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. 
  • Lung inflammation stalls Th17-cell migration en route to the central nervous system during the development of experimental autoimmune encephalomyelitis. 
  • Lung stem cells: looking beyond the hype. 
  • Lupus-specific antiribonucleoprotein B cell tolerance in nonautoimmune mice is maintained by differentiation to B-1 and governed by B cell receptor signaling thresholds. 
  • Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. 
  • Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines. 
  • Lymphocyte Migration in L-Selectin-Deficient Mice: Altered Subset Migration and Aging of the Immune System 
  • Lymphocyte accumulation in the spleen of retinoic acid receptor-related orphan receptor gamma-deficient mice. 
  • Lymphocyte activation markers may predict the presence of donor specific alloreactivity in pediatric living related liver transplant recipients. 
  • Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. 
  • Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcgammaRI, FcgammaRIII, and FcgammaRIV. 
  • MANUFACTURING OF ALLOGENEIC HUMAN CORD TISSUE MESENCHYMAL STROMAL CELLS: INITIAL RESULTS OF A PHASE I CLINICAL TRIAL IN CHILDREN WITH AUTISM SPECTRUM DISORDER 
  • MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages. 
  • MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment 
  • MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. 
  • MHC class II alleles associated with clinical and immunological manifestations of HIV-1 infection among children in Catalonia, Spain. 
  • MHC-restricted recognition of autologous melanoma by tumor-specific cytotoxic T cells. Evidence for restriction by a dominant HLA-A allele. 
  • MLN4924, a Novel Investigational Inhibitor Of NEDD8-Activating Enzyme (NAE), In Adult Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS): Results From Multiple Dosing Schedules In a Phase 1 Study 
  • MYH9 and APOL1 are both associated with sickle cell disease nephropathy. 
  • Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. 
  • Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart. 
  • Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions. 
  • Major histocompatibility complex variation and evolution at a single, expressed DQA locus in two genera of elephants. 
  • Making sense of hormone crosstalk during plant immune responses. 
  • Malaria parasites and red cell variants: when a house is not a home. 
  • Maleylated-BSA induces hydrolysis of PIP2, fluxes of Ca2+, NF-kappaB binding, and transcription of the TNF-alpha gene in murine macrophages. 
  • Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures. 
  • Management of adverse events associated with idelalisib treatment: expert panel opinion. 
  • Mannose Receptor 1 Mediates Cellular Uptake and Endosomal Delivery of CpG-Motif Containing Oligodeoxynucleotides 
  • Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a monoclonal antibody to gp46. 
  • Maribavir prophylaxis for prevention of cytomegalovirus infection in allogeneic stem cell transplant recipients: a multicenter, randomized, double-blind, placebo-controlled, dose-ranging study. 
  • Marked QRS complex abnormalities and sodium channel blockade by propoxyphene reversed with lidocaine. 
  • Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. 
  • Markers of endothelial dysfunction and leucocyte activation in Saudi and non-Saudi haplotypes of sickle cell disease 
  • Marrow transplantation for Fanconi anemia with or without leukemic transformation: an update of the Seattle experience. 
  • Marrow transplantation for chronic myeloid leukemia: the influence of plasma busulfan levels on the outcome of transplantation. 
  • Marrow transplantation in hepatitis-associated aplastic anemia. 
  • Marrow transplantation with or without donor buffy coat cells for 65 transfused aplastic anemia patients. 
  • Mast cell activation by Mycobacterium tuberculosis: mediator release and role of CD48. 
  • Mast cell activators: a new class of highly effective vaccine adjuvants. 
  • Mast cell desensitization inhibits calcium flux and aberrantly remodels actin. 
  • Mast cell interleukin-10 drives localized tolerance in chronic bladder infection. 
  • Mast cell phagocytosis of FimH-expressing enterobacteria. 
  • Mast cell-derived particles deliver peripheral signals to remote lymph nodes. 
  • Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection. 
  • Mast cell-orchestrated immunity to pathogens. 
  • Mast cells and basophils in innate immunity. 
  • Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues. 
  • Mast cells enable heightened humoral immunity during infection 
  • Mast cells process bacterial Ags through a phagocytic route for class I MHC presentation to T cells. 
  • Matched and mismatched metabolic fuels in lymphocyte function. 
  • Matched-related donor transplantation for sickle cell disease: report from the Center for International Blood and Transplant Research. 
  • Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission. 
  • Maternal Humoral Immune Correlates of Peripartum Transmission of Clade C HIV-1 in the Setting of Peripartum Antiretrovirals. 
  • Maximal adjuvant activity of nasally delivered IL-1α requires adjuvant-responsive CD11c(+) cells and does not correlate with adjuvant-induced in vivo cytokine production. 
  • Maximizing the retention of antigen specific lymphocyte function after cryopreservation. 
  • Measuring therapeutic response in chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. Response Criteria Working Group report. 
  • Mechanics of T cell receptor gene rearrangement. 
  • Mechanisms of heparanase inhibitors in cancer therapy. 
  • Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of Mac-1(CD11b/CD18) and urokinase receptor (CD87). 
  • Mechanisms that diversify an otherwise intrinsically processive Trav-Trqj recombination program 
  • Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy. 
  • Melanoma immunotherapy using mature DCs expressing the constitutive proteasome 
  • Melphalan containing cytoreduction results in a good overall survival (OS) in pediatric patients with relapse or refractory AML undergoing unrelated umbilical cord blood transplantation (UCBT). 
  • Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. 
  • Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants. 
  • Meningeal whole mount preparation and characterization of neural cells by flow cytometry. 
  • Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis. 
  • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. 
  • Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing. 
  • Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. 
  • Metabolic Barriers to T Cell Function in Tumors. 
  • Metabolic pathways in T cell fate and function. 
  • Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation. 
  • Metabolic regulation of T lymphocytes. 
  • Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. 
  • Metabolism and autophagy in the immune system: immunometabolism comes of age. 
  • Metabolism of PGE2 by prostaglandin dehydrogenase is essential for remodeling the ductus arteriosus. 
  • Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days 
  • Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures. 
  • Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. 
  • Metformin reverses fatty liver disease in obese, leptin-deficient mice. 
  • Methodology for updating published evidence-based reviews evaluating the role of blood and marrow transplantation in the treatment of selected diseases: a policy statement by the American Society for Blood and Marrow Transplantation. 
  • Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. 
  • Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. 
  • Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. 
  • Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome. 
  • MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes 
  • MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes. 
  • MicroRNAs as mediators of viral evasion of the immune system. 
  • Microassay for the photometric quantitation of cell-associated plasminogen activator using a chromogenic tripeptide substrate. 
  • Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish. 
  • Microcytic anemia in mk/mk mice is not corrected by retroviral-mediated gene transfer of wild-type p45 NF-E2. 
  • Microparticles as a source of extracellular DNA. 
  • Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus. 
  • Microparticles as mediators of cellular cross-talk in inflammatory disease. 
  • Minimal data reporting standards for serological testing for histocompatibility 
  • Mitochondrial dysfunction in ataxia-telangiectasia. 
  • Mixed leukocyte culture reactivity and graft-versus-host disease in HLA-identical marrow transplantation for leukemia. 
  • Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. 
  • Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis. 
  • Mobilization of dendritic cells from patients with breast cancer into peripheral blood stem cell leukapheresis samples using Flt-3-Ligand and G-CSF or GM-CSF. 
  • Mobilization of peripheral blood stem cells following myelosuppressive chemotherapy: a randomized comparison of filgrastim, sargramostim, or sequential sargramostim and filgrastim. 
  • Model for leukocyte regulation by chemoattractant receptors: roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism. 
  • Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities. 
  • Modification of the pharmacokinetics of high-dose cyclophosphamide and cisplatin by antiemetics. 
  • Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge. 
  • Modulating hedgehog signaling can attenuate the severity of osteoarthritis. 
  • Modulation of CD45 tyrosine phosphatase activity by antigen. 
  • Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens. 
  • Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. 
  • Modulation of mouse peritoneal macrophage Ia and human peritoneal macrophage HLA-DR expression by alpha 2-macroglobulin "fast" forms. 
  • Modulation of natural IgM binding and complement activation by natural IgG antibodies: a role for IgG anti-Gal alpha1-3Gal antibodies. 
  • Modulation of nonneutralizing HIV-1 gp41 responses by an MHC-restricted TH epitope overlapping those of membrane proximal external region broadly neutralizing antibodies 
  • Modulation of the intracellular Ca²⁺ and inositol trisphosphate concentrations in murine T lymphocytes by the glycosylphosphatidylinositol- anchored protein sgp-60 
  • Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes. 
  • Molecular and cellular pathogenesis of heparin-induced thrombocytopenia (HIT). 
  • Molecular and structural analysis of nuclear localizing anti-DNA lupus antibodies. 
  • Molecular basis for elliptocytosis associated with glycophorin C and D deficiency in the Leach phenotype. 
  • Molecular basis for paradoxical carriers of adenosine deaminase (ADA) deficiency that show extremely low levels of ADA activity in peripheral blood cells without immunodeficiency. 
  • Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro. 
  • Molecular control of iron metabolism. 
  • Molecular control of steady-state dendritic cell maturation and immune homeostasis. 
  • Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution. 
  • Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation. 
  • Molecular mapping of the Cromer blood group Cra and Tca epitopes of decay accelerating factor: toward the use of recombinant antigens in immunohematology. 
  • Molecular subtype classification of formalin-fixed, paraffin-embedded diffuse large B-cell lymphoma samples on the ICEPlex® system. 
  • Monitoring of kidney and simultaneous pancreas-kidney transplantation rejection by release of donor-specific, soluble HLA class I. 
  • Monoclonal antibodies against human T cell leukemia-lymphoma virus (HTLV) p24 internal core protein. Use as diagnostic probes and cellular localization of HTLV. 
  • Monoclonal antibodies reactive with human T cell lymphotropic virusI (HTLVI) p19 internal core protein: cross-reactivity with normal tissues and differential reactivity with HTLV types I and II. 
  • Monoclonal antibodies to CD2 and lymphocyte function-associated antigen 3 inhibit human thymic epithelial cell-dependent mature thymocyte activation. 
  • Monoclonal antibody against human T cell leukemia virus p19 defines a human thymic epithelial antigen acquired during ontogeny. 
  • Monoclonal antibody definition of T cell acute leukemia: a Pediatric Oncology Group study. 
  • Monocyte adhesion in patients with bone marrow fibrosis is required for the production of fibrogenic cytokines. Potential role for interleukin-1 and TGF-beta. 
  • Monocyte responsiveness to chemotactic stimuli is a property of a subpopulation of cells that can respond to multiple chemoattractants. 
  • Monocytoid differentiation of freshly isolated human myeloid leukemia cells and HL-60 cells induced by the glutamine antagonist acivicin. 
  • Morbidity and mortality in chronically transfused subjects with thalassemia and sickle cell disease: A report from the multi-center study of iron overload. 
  • Morbidity and mortality of chronic GVHD after hematopoietic stem cell transplantation from HLA-identical siblings for patients with aplastic or refractory anemias. 
  • More than skin deep: connecting melanocyte pigmentation and angiogenic diseases. 
  • Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys. 
  • Mouse CD20 expression and function. 
  • Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses. 
  • Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. 
  • Moving upstream in the war on WNTs. 
  • Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination. 
  • Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease. 
  • Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4. 
  • Mucosal immunity to HIV-1: systemic and vaginal antibody responses after intranasal immunization with the HIV-1 C4/V3 peptide T1SP10 MN(A). 
  • Mucosal immunity to infection with implications for vaccine development. 
  • Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A. 
  • Multi-Center US Intergroup Study of Intensive Chemotherapy Plus Dasatinib Followed By Allogeneic Stem Cell Transplant in Patients with Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Younger Than 60 
  • Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome. 
  • Multi-site evaluation of the BD Stem Cell Enumeration Kit for CD34⁺ cell enumeration on the BD FACSCanto II and BD FACSCalibur flow cytometers 
  • Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP). 
  • Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria. 
  • Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. 
  • Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. 
  • Multifunctional regulators of cell growth are differentially expressed in anergic murine B cells. 
  • Multiple CTL specificities against autologous HIV-1-infected BLCLs. 
  • Multiple Myeloma Patient Experience with Financial Toxicity: Findings from the Cancer Experience Registry 
  • Multiple Myeloma Symptom Burden, Perceived Control, and Quality of Life: Findings from the Cancer Experience Registry 
  • Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development. 
  • Multiple gamma c-dependent cytokines regulate T-cell development. 
  • Multiple genetic lesions in acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma. 
  • Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand. 
  • Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells. 
  • Multiplex assay for simultaneous measurement of antibodies to multiple Plasmodium falciparum antigens. 
  • Multiplex assay reliability and long-term intra-individual variation of serologic inflammatory biomarkers. 
  • Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice. 
  • Murine CD7 shares antigenic cross-reactivity with HSP-60. 
  • Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis. 
  • Murine monoclonal anti-T cell antibodies for treatment of steroid-resistant acute graft-versus-host disease. 
  • Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function. 
  • Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression. 
  • Muscle autoantibodies in myasthenia gravis: beyond diagnosis? 
  • Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. 
  • Mutations in activation-induced cytidine deaminase in patients with hyper IgM syndrome. 
  • Mutations in the glucose-6-phosphatase gene are associated with glycogen storage disease types 1a and 1aSP but not 1b and 1c. 
  • Myeloablative Conditioning with Clofarabine and Busulfan X 4 (CloBu4) Is Well Tolerated, Facilitates Secure Engraftment, and Exhibits Significant Anti-Tumor Activity against Non-Remission Hematologic Malignancies Including AML 
  • Myeloablative intravenous busulfan/fludarabine conditioning does not facilitate reliable engraftment of dual umbilical cord blood grafts in adult recipients. 
  • Myeloablative transplantation using either cord blood or bone marrow leads to immune recovery, high long-term donor chimerism and excellent survival in chronic granulomatous disease. 
  • Myelodysplastic syndrome evolving from aplastic anemia treated with immunosuppressive therapy: efficacy of hematopoietic stem cell transplantation. 
  • Myeloid Cells in the Central Nervous System. 
  • Myocardial beta-adrenergic receptor signaling in vivo: insights from transgenic mice. 
  • N-terminal and central regions of the human CD44 extracellular domain participate in cell surface hyaluronan binding. 
  • N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. 
  • NCI, NHLBI first international consensus conference on late effects after pediatric hematopoietic cell transplantation: state of the science, future directions. 
  • NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • NIH Consensus development project on criteria for clinical trials in chronic graft-versus-host disease: II. The 2014 Pathology Working Group Report. 
  • NK cell receptors 2B4 and NKp46 utilize Fc epsilon RIy for cell-mediated cytotoxicity 
  • NK cell-extrinsic IL-18 signaling is required for efficient NK-cell activation by vaccinia virus. 
  • NK susceptibility varies inversely with target cell class I HLA antigen expression. 
  • NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway. 
  • NKG2D-mediated activation of cytotoxic lymphocytes: unique signaling pathways and distinct functional outcomes. 
  • NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells. 
  • NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses. 
  • NO adducts in mammalian red blood cells: too much or too little? 
  • NO/redox disequilibrium in the failing heart and cardiovascular system. 
  • NOS: modulator, not mediator of cardiac performance. 
  • NOTCH signaling in skeletal progenitors is critical for fracture repair. 
  • National Cancer Institute, National Heart, Lung and Blood Institute/Pediatric Blood and Marrow Transplantation Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: the need for pediatric-specific long-term follow-up guidelines. 
  • Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. 
  • Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume. 
  • Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways. 
  • Natural killer cell-enriched donor lymphocyte infusions from A 3-6/6 HLA matched family member following nonmyeloablative allogeneic stem cell transplantation. 
  • Natural killing target antigens as inducers of interferon: studies with an immunoselected, natural killing-resistant human T lymphoblastoid cell line. 
  • Naïve T cells are maintained in the periphery during the first 3 months of acute HIV-1 infection: implications for analysis of thymus function. 
  • Necrosis-dependent and independent signaling of the RIP kinases in inflammation 
  • Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. 
  • Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. 
  • Negative regulation of T cell activation and autoimmunity by the transmembrane adaptor protein LAB. 
  • Neighborhood watch orchestrates liver regeneration. 
  • Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation. 
  • Neisseria gonorrhoeae-induced human defensins 5 and 6 increase HIV infectivity: role in enhanced transmission. 
  • Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801. 
  • Neonates support lymphopenia-induced proliferation. 
  • Neopterin production by HIV-1-infected mononuclear phagocytes. 
  • Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells. 
  • Neuroimmunology in 2017: The central nervous system: privileged by immune connections. 
  • Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect. 
  • Neuronal and glial cell composition in a mouse brain slice culture model is useful in developing human cord blood derived cellular therapies for neonatal hypoxic-ischemic brain injury 
  • Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury. 
  • Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. 
  • Neutralizing and infection-enhancing antibody responses do not correlate with the differential pathogenicity of SIVmac239delta3 in adult and infant rhesus monkeys. 
  • Neutralizing antibodies take a swipe at HIV in vivo. 
  • Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations. 
  • Neutrophil margination, sequestration, and emigration in the lungs of L-selectin-deficient mice. 
  • New CD from the B cell section of the Fifth International Workshop on Human Leukocyte Differentiation Antigens. 
  • New approaches in progenitor cell-supported chemotherapy for stage IV breast cancer 
  • New approaches to HIV vaccine development. 
  • New clues to the molecular pathogenesis of Burkitt lymphoma revealed through next-generation sequencing 
  • New clues to the molecular pathogenesis of Burkitt lymphoma revealed through next-generation sequencing. 
  • New concepts in macrophage ontogeny in the adult neural retina. 
  • New insights into E-protein function in lymphocyte development. 
  • New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunodeficiency associated with adenosine deaminase deficiency. 
  • New insights into mononuclear phagocyte biology from the visual system. 
  • New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone. 
  • New ways in which GLP-1 can regulate glucose homeostasis. 
  • Nitric oxide and redox mechanisms in the immune response. 
  • Nitric oxide enhancement of fludarabine cytotoxicity for B-CLL lymphocytes. 
  • Nitric oxide in the human respiratory cycle. 
  • Nitric oxide modulation of human leukemia cell differentiation and gene expression. 
  • Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: a review. 
  • Non-erythroid effects of erythropoietin. 
  • Non-myeloablative umbilical cord blood transplantation. 
  • Noncytolytic CD8 T cell-mediated suppression of HIV replication. 
  • Noninvasive cineangiography by magnetic resonance global coherent free precession. 
  • Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node. 
  • Nonmyeloablative allogeneic hematopoietic stem cell transplantation for congenital sideroblastic anemia. 
  • Nonpermissive HLA-DPB1 mismatch increases mortality after myeloablative unrelated allogeneic hematopoietic cell transplantation. 
  • Normal human bone marrow precursors that express terminal deoxynucleotidyl transferase include T-cell precursors and possible lymphoid stem cells. 
  • Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. 
  • Normal neutrophil function in cathepsin G-deficient mice. 
  • North American Cooperative Group Members' Patterns of Blood Products Transfusion for Patients with Acute Leukemia 
  • Notch 1 signaling regulates peripheral T cell activation. 
  • Notch promotes radioresistance of glioma stem cells. 
  • Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism 
  • Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. 
  • Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients. 
  • Novel epinephrine and cyclic AMP-mediated activation of BCAM/Lu-dependent sickle (SS) RBC adhesion. 
  • Novel intranasal pertussis vaccine based on bacterium-like particles as a mucosal adjuvant 
  • Novel nuclear target for thrombin: activation of the Elk1 transcription factor leads to chemokine gene expression. 
  • Novel role for surfactant protein A in gastrointestinal graft-versus-host disease. 
  • Novel role of gastric releasing peptide-mediated signaling in the host response to influenza infection. 
  • Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. 
  • Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. 
  • Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. 
  • Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi. 
  • Nutrients and the microenvironment to feed a T cell army. 
  • Nutritional effects on T-cell immunometabolism. 
  • OMIP-036: Co-inhibitory receptor (immune checkpoint) expression analysis in human T cell subsets. 
  • Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation. 
  • Obstetric and Gynecological History in Sickle Cell Disease Females 
  • Odorant receptors and desensitization proteins colocalize in mammalian sperm. 
  • Older patients with myeloma derive similar benefit from autologous transplantation. 
  • Oligoclonal TRBV gene usage among CD8(+) T cells in monoclonal B lymphocytosis and CLL. 
  • Once daily i.v. busulfan and fludarabine (i.v. Bu-Flu) compares favorably with i.v. busulfan and cyclophosphamide (i.v. BuCy2) as pretransplant conditioning therapy in AML/MDS. 
  • Once-daily intravenous busulfan and fludarabine: clinical and pharmacokinetic results of a myeloablative, reduced-toxicity conditioning regimen for allogeneic stem cell transplantation in AML and MDS. 
  • Oncogenic mutations in ras create HLA-A2.1 binding peptides but affect their extracellular antigen processing. 
  • One-stop-shop tumor imaging: buy hypoxia, get lactate free. 
  • Ontogeny of the human thymus during fetal development. 
  • Opiates transdeactivate chemokine receptors: delta and mu opiate receptor-mediated heterologous desensitization. 
  • Opioid management and dependency among adult patients with sickle cell disease. 
  • Opioid patient controlled analgesia use during the initial experience with the IMPROVE PCA trial: a phase III analgesic trial for hospitalized sickle cell patients with painful episodes. 
  • Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors. 
  • Opsonized zymosan-stimulated granulocytes-activation and activity of the superoxide-generating system and membrane potential changes. 
  • Optic disc and retinal microvasculopathy after high-dose chemotherapy and autologous hematopoietic progenitor cell support. 
  • Optimal Practices in Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies. 
  • Optimization and qualification of an Fc Array assay for assessments of antibodies against HIV-1/SIV. 
  • Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1 
  • Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1. 
  • Oral immunogenicity of the plant proteinase bromelain. 
  • Organ iron accumulation in chronically transfused children with sickle cell anaemia: baseline results from the TWiTCH trial. 
  • Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development. 
  • Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. 
  • Osteopontin induces ubiquitin-dependent degradation of STAT1 in RAW264.7 murine macrophages. 
  • Our cells get stressed too! Implications for human disease. 
  • Outcome of transplantation for acute myelogenous leukemia in children with Down syndrome. 
  • Outcomes after Hematopoietic Stem Cell Transplantation for Children with I-Cell Disease 
  • Outcomes after Second Hematopoietic Cell Transplantation in Children and Young Adults with Relapsed Acute Leukemia. 
  • Outcomes and costs of autologous stem cell mobilization with chemotherapy plus G-CSF vs G-CSF alone 
  • Outcomes for Older Patients with Acute Myeloid Leukemia Admitted to the Intensive Care Unit 
  • Outcomes in hepatitis C virus seropositive lymphoma and myeloma patients after autologous stem cell transplantation. 
  • Outcomes of Allogeneic Hematopoietic Cell Transplantation in Patients with Myelofibrosis with Prior Exposure to Janus Kinase 1/2 Inhibitors. 
  • Outcomes of Maintenance Therapy with Bortezomib after Autologous Stem Cell Transplantation for Patients with Multiple Myeloma. 
  • Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression. 
  • Outcomes of Unrelated Umbilical Cord Blood Transplantation In Pediatric Patients With Primary and Secondary Myelodysplastic Syndromes 
  • Outcomes of adults with acute lymphoblastic leukemia relapsing after allogeneic hematopoietic stem cell transplantation. 
  • Outcomes of allogeneic hematopoietic cell transplantation in patients with dyskeratosis congenita. 
  • Outcomes of fludarabine, high dose cytarabine and granulocyte-colony stimulating factor (FLAG) as re-induction for residual acute myeloid leukemia on day 14 bone marrow. 
  • Outcomes of front-line ibrutinib treated CLL patients excluded from landmark clinical trial. 
  • Outcomes of second allogeneic hematopoietic stem cell transplantation for patients with acute lymphoblastic leukemia. 
  • Outcomes of stem cell transplant patients with acute respiratory failure requiring mechanical ventilation in the United States. 
  • Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning. 
  • Outcomes of unrelated umbilical cord blood transplantation in pediatric patients with myelodysplastic syndrome 
  • Outcomes of unrelated umbilical cord blood transplantation in pediatric patients with myelodysplastic syndrome 
  • Overexpression of the high affinity choline transporter in cortical regions affected by Alzheimer's disease. Evidence from rapid autopsy studies. 
  • Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation. 
  • Overexpression of wild-type retinoic acid receptor alpha (RARalpha) recapitulates retinoic acid-sensitive transformation of primary myeloid progenitors by acute promyelocytic leukemia RARalpha-fusion genes. 
  • Overlapping roles for L-selectin and P-selectin in antigen-induced immune responses in the microvasculature. 
  • Oxidative damage-induced inflammation initiates age-related macular degeneration. 
  • Oxidized alpha2-macroglobulin (alpha2M) differentially regulates receptor binding by cytokines/growth factors: implications for tissue injury and repair mechanisms in inflammation. 
  • Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2. 
  • Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation. 
  • P- and L-selectin mediate distinct but overlapping functions in endotoxin-induced leukocyte-endothelial interactions in the rat mesenteric microcirculation. 
  • P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808. 
  • P-selectin glycoprotein ligand-1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells. 
  • P135 New frequent HLA-DPB1/DPA1 haplotypes in low resolution typing 
  • P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. 
  • PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma. 
  • PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue. 
  • PD-L1 serves as a double agent in separating GVL from GVHD. 
  • PET concerns in bevacizumab treatment. 
  • PF4/heparin complexes are T cell-dependent antigens. 
  • PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI. 
  • PIG-A, DAF and proto-oncogene expression in paroxysmal nocturnal haemoglobinuria-associated acute myelogenous leukaemia blasts. 
  • PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. 
  • Pain and other non-neurological adverse events in children with sickle cell anemia and previous stroke who received hydroxyurea and phlebotomy or chronic transfusions and chelation: results from the SWiTCH clinical trial. 
  • Palliative Care For Patients With Hematologic Malignancies: A Profile Of Patients With Blood Cancers Referred To The Choice Hospice Network 
  • Palmitoylation-dependent plasma membrane transport but lipid raft-independent signaling by linker for activation of T cells. 
  • Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization. 
  • Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells. 
  • Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1 (Retracted article. See vol. 123, pg. 2752, 2013) 
  • Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1. 
  • Parent education and biologic factors influence on cognition in sickle cell anemia. 
  • Partially HLA matched, non-myeloablative allogeneic transplantation 
  • Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation. 
  • Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation. 
  • Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation. 
  • Partners in anti-crime: how interferon-inducible GTPases and autophagy proteins team up in cell-intrinsic host defense. 
  • Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques. 
  • Pathogenesis of NOD diabetes is initiated by reactivity to the insulin B chain 9-23 epitope and involves functional epitope spreading. 
  • Pathogenesis of autoimmunity in pemphigus. 
  • Patient perspectives on physical function after allogeneic hematopoietic stem cell transplantation: a qualitative study. 
  • Patient-Reported Distress in Hodgkin Lymphoma Patients on Active Therapy Vs. Long-Term Survivors 
  • Patients welcome the Sickle Cell Disease Mobile Application to Record Symptoms via Technology (SMART). 
  • Pattern recognition molecule mindin promotes intranasal clearance of influenza viruses. 
  • Patterns of microRNA expression characterize stages of human B-cell differentiation. 
  • Pax7 expressing cells contribute to dermal wound repair, regulating scar size through a β-catenin mediated process. 
  • Payment and Care for Hematopoietic Cell Transplantation Patients: Toward a Specialized Medical Home for Complex Care Patients 
  • Peg-L-Asparaginase (PL-A) in advanced multiple myeloma (MM): A novel agent with therapeutic potential. 
  • Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling. 
  • Perceptions of Prognosis and Treatment Risk in Older Patients with Acute Myeloid Leukemia 
  • Performance of serum-supplemented and serum-free media in IFNgamma Elispot Assays for human T cells. 
  • Pericardial Effusion Following Unrelated Umbilical Cord Blood Transplantation: Analysis in a Cohort Of 423 Pediatric Patients Transplanted at a Single Center 
  • Peripheral and central mechanisms of inflammatory pain, with emphasis on MAP kinases. 
  • Peripheral blood allogeneic microchimerism in lung and cardiac allograft recipients. 
  • Peripheral blood progenitor cell mobilization using stem cell factor in combination with filgrastim in breast cancer patients. 
  • Peripheral blood stem cell transplantation in breast cancer. 
  • Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia. 
  • Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-γ+CD4+ T cell numbers during colitis development in mice. 
  • Peritoneal fluid and plasma levels of human macrophage colony-stimulating factor in relation to peritoneal fluid macrophage content. 
  • Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice. 
  • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. 
  • Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. 
  • Pevonedistat (MLN4924), a First-in-Class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukaemia and myelodysplastic syndromes: a phase 1 study. 
  • Pevonedistat (MLN4924), an Investigational, First-in-Class NAE Inhibitor, in Combination with Azacitidine in Elderly Patients with Acute Myeloid Leukemia (AML) Considered Unfit for Conventional Chemotherapy: Updated Results from the Phase 1 C15009 Trial 
  • Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, combined with azacitidine in patients with AML. 
  • Phagocytosis and killing of Cryptococcus neoformans by rat alveolar macrophages in the absence of serum. 
  • Pharmacogenetics of minimal residual disease response in children with B-precursor acute lymphoblastic leukemia: a report from the Children's Oncology Group. 
  • Pharmacokinetics of once-daily IV busulfan as part of pretransplantation preparative regimens: a comparison with an every 6-hour dosing schedule. 
  • Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models. 
  • Phase 1 trial of rituximab, lenalidomide, and ibrutinib in previously untreated follicular lymphoma: Alliance A051103. 
  • Phase 1 trial study of 131I-labeled chimeric 81C6 monoclonal antibody for the treatment of patients with non-Hodgkin lymphoma. 
  • Phase 1/2 trial of GCLAM with dose-escalated mitoxantrone for newly diagnosed AML or other high-grade myeloid neoplasms. 
  • Phase 2 study of the g209-2M melanoma peptide vaccine and low-dose interleukin-2 in advanced melanoma: Cancer and Leukemia Group B 509901. 
  • Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720. 
  • Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure. 
  • Phase I and pharmacokinetic study of docetaxel combined with melphalan and carboplatin, with autologous hematopoietic progenitor cell support, in patients with advanced refractory malignancies. 
  • Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia. 
  • Phase I evaluation of gemcitabine, mitoxantrone, and their effect on plasma disposition of fludarabine in patients with relapsed or refractory acute myeloid leukemia. 
  • Phase I trial of lenalidomide in combination with plerixafor for relapsed/refractory chronic lymphocytic leukemia (CLL): follow-up and correlative analysis 
  • Phase I/II randomized trial of safety and immunogenicity of LIPO-5 alone, ALVAC-HIV (vCP1452) alone, and ALVAC-HIV (vCP1452) prime/LIPO-5 boost in healthy, HIV-1-uninfected adult participants. 
  • Phase II Study of Single Agent Clofarabine in Previously Untreated Older Adult Patients with Acute Myelogenous Leukemia (AML) Unlikely to Benefit from Standard Induction Chemotherapy 
  • Phase II Study of the Oral MEK Inhibitor AZD6244 in Advanced Acute Myeloid Leukemia (AML) 
  • Phase II Trial of Graft-versus-Host Disease Prophylaxis with Post-Transplantation Cyclophosphamide after Reduced-Intensity Busulfan/Fludarabine Conditioning for Hematological Malignancies. 
  • Phase II Trial of High-Dose Gemcitabine/Busulfan/Melphalan with Autologous Stem Cell Transplantation for Primary Refractory or Poor-Risk Relapsed Hodgkin Lymphoma 
  • Phase II studies of different schedules and doses of the farnesyl transferase inhibitor tipifarnib (R115777, zarnestra, NSC-702818) for patients of age 70 or older with previously untreated acute myeloid leukemia (AML): A north American intergroup study (S0432) 
  • Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing. 
  • Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells. 
  • Philadelphia chromosome mosaicism at diagnosis in chronic myeloid leukemia: clinical correlates and effect on imatinib mesylate treatment outcome. 
  • Phorbol myristate acetate mediates redistribution of protein kinase C in human neutrophils: potential role in the activation of the respiratory burst enzyme. 
  • Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. 
  • Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. 
  • Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP 
  • Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. 
  • Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition. 
  • Physiological disposition and metabolic fate of infused pentoses in man. 
  • Pillars Article: Identification of a Putative Second T-cell Receptor. Nature. 1986. 322: 145-149. 
  • Pioneering geneticist Mary-Claire King receives the 2014 Lasker~Koshland Special Achievement Award in Medical Science. 
  • Placenta growth factor in sickle cell disease: association with hemolysis and inflammation. 
  • Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. 
  • Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. 
  • Plasma microRNA-586 is a new biomarker for acute graft-versus-host disease. 
  • Platelet transfusions: utilization and associated costs in a tertiary care hospital. 
  • Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154 
  • Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154 
  • Platelet-rich plasma and peripheral nerve regeneration: a potential contraindication to its use after tumor excision. 
  • Platelets deliver costimulatory signals to antigen-presenting cells: A potential bridge between injury and immune activation 
  • Pleiotrophin mediates hematopoietic regeneration via activation of RAS. 
  • Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. 
  • Plerixafor Plus Granulocyte Colony-Stimulating Factor for Patients with Non-Hodgkin Lymphoma and Multiple Myeloma: Long-Term Follow-Up Report. 
  • Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma. 
  • Polychromatic plots: graphical display of multidimensional data. 
  • Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys. 
  • Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway. 
  • Polyribonucleotides induce nitric oxide production by human monocyte-derived macrophages. 
  • Polyvalent human immunodeficiency virus synthetic immunogen comprised of envelope gp120 T helper cell sites and B cell neutralization epitopes. 
  • Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. 
  • Population prevalence of diagnosed primary immunodeficiency diseases in the United States. 
  • Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL. 
  • Positive selection of CD34+ hematopoietic progenitor cells for transplantation. 
  • Post transplant CD8+ gammadelta T-cell lymphoma associated with human herpes virus-6 infection. 
  • Post-mortem incidental finding of cytomegalovirus oophoritis after an allogeneic stem cell transplant. 
  • Post-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease. 
  • Post-transplantation B cell function in different molecular types of SCID. 
  • Postoperative Venous Thromboembolism in Children Is Increased in Setting of Cancer or Infection 
  • Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine. 
  • Posttranscriptional m 6 A Editing of HIV-1 mRNAs Enhances Viral Gene Expression 
  • Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. 
  • Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1. 
  • Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. 
  • Potentially Avoidable Hospitalizations in Older Patients with Acute Myeloid Leukemia (AML) 
  • Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. 
  • Potentiation of beta-adrenergic signaling by adenoviral-mediated gene transfer in adult rabbit ventricular myocytes. 
  • Pre-T cell receptor's clashing signals: "should I stay or should I go". 
  • Pre-Transfusion Rejuvenation of RBCs for Red Blood Cell Exchange: Report of Feasibility 
  • Pre-transplant Screening for Non-HLA Antibodies: Who should be Tested? 
  • Precision and linearity targets for validation of an IFNgamma ELISPOT, cytokine flow cytometry, and tetramer assay using CMV peptides. 
  • Preclinical efficacy of MEK inhibition in Nras-mutant AML. 
  • Prediction of CR following a second course of '7+3' in patients with newly diagnosed acute myeloid leukemia not in CR after a first course. 
  • Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy. 
  • Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation. 
  • Preemptive donor apoptotic cell infusions induce IFN-γ-producing myeloid-derived suppressor cells for cardiac allograft protection. 
  • Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. 
  • Pregnancy in patients with thrombocytopenia and absent radii (TAR) syndrome. 
  • Prenatal sensitization of a postnatal trigger for metabolic disease. 
  • Preparing an oncolytic poliovirus recombinant for clinical application against glioblastoma multiforme. 
  • Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. 
  • Pretransplant exposure to donor HLA-DR antigen in random transfusion units and the development of donor antigen-specific hyporeactivity. 
  • Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). 
  • Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study. 
  • Prevalence of HTLV-I-associated T-cell lymphoma 
  • Prevalence of HTLV-I-associated T-cell lymphoma. 
  • Prevalence of heterozygotes for hemochromatosis in the white population of the United States. 
  • Prevalence of self-reported sleep dysfunction before allogeneic hematopoietic cell transplantation 
  • Prevalence, predictors and outcomes of cardiopulmonary resuscitation in hospitalized adult stem cell transplant recipients in the United States: not just opening the black box but exploring an opportunity to optimize! 
  • Prevention Of Acute GvHD During Haplo-BMT: Evaluating The Efficacy Of T-Cell Costimulation Blockade Using A Novel Rhesus Macaque Transplant Model 
  • Prevention of Acute GvHD During MHC Haploidentical BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model. 
  • Prevention of Acute GvHD during Haplo-BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model 
  • Prevention of Vaginal Transmission of Simian-Human Immunodeficiency Virus (SHIV) in Rhesus Monkeys by Small-molecule CD4-mimetic Compounds 
  • Prevention of preeclampsia. 
  • Prevention trumps treatment of antibody-mediated transplant rejection. 
  • Previous donor pregnancy as a risk factor for acute graft-versus-host disease in patients with aplastic anaemia treated by allogeneic marrow transplantation. 
  • Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation. 
  • Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions. 
  • Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes. 
  • Prognostic Methylation Markers for Survival in Cytogenetically Normal AML Patients Treated on SWOG Trials 
  • Prognostic Significance of FLT3 and NPM1 Mutations in Adults of Age 18-60 with De Novo Acute Myeloid Leukemia (AML) on SWOG S0106 Study: A Study by FHCRC and SWOG 
  • Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia. 
  • Prognostic factors in childhood T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study. 
  • Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. 
  • Prognostic significance of occult tumor cells in the apheresis products of patients with advanced breast cancer receiving high-dose chemotherapy and autologous hematopoietic progenitor cell support. 
  • Programmed Necrosis in the Cross Talk of Cell Death and Inflammation 
  • Progress toward Development of a Vaccine against Congenital Cytomegalovirus Infection. 
  • Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification. 
  • Proinflammatory state, hepcidin, and anemia in older persons. 
  • Prolonged Administration of Azacitidine with or without Entinostat Increases Rate of Hematologic Normalization for Myelodysplastic Syndrome and Acute Myeloid Leukemia with Myelodysplasia-Related Changes: Results of the US Leukemia Intergroup Trial E1905 
  • Prolonged disease control by nonmyeloablative allogeneic transplantation for metastatic breast cancer. 
  • Prolonged disease-free survival in patients with acute myeloid leukemia in first relapse treated with gemtuzumab ozogamicin (Mylotarg (TM), CMA-676) followed by hematopoietic stem cell transplantation. 
  • Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report. 
  • Prolonged subcutaneous administration of recombinant alpha 2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: effect on remission duration and survival: Cancer and Leukemia Group B study 8583. 
  • Prometheus revisited 
  • Promising vaccines for treating glioblastoma. 
  • Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes. 
  • Prophylaxis and treatment of acute graft-versus-host disease. 
  • Prospect of rindopepimut in the treatment of glioblastoma. 
  • Prospective Implementation of Multi-Disciplinary Obstetric Team Decreases the Mortality Rate of Pregnant Women with Sickle Cell Disease in Ghana 
  • Prospective Study of Acute Myeloid Leukemia (AML) Clinical Epidemiology and Cytogenetic Risk Group in Older Adults in the ECOG-ACRIN E2906 Clinical Trial: The Acute Leukemia Epidemiology, Survival and Endpoints (ALESE) Study 
  • Prospective analysis of TEL and MLL gene rearrangements in childhood acute lymphoblastic leukemia: A Children's Oncology Group study. 
  • Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling. 
  • Prostanoids and blood pressure: which way is up? 
  • Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. 
  • Protease activity of normal and PHA stimulated human lymphocytes. 
  • Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis. 
  • Protection against malaria at 1 year and immune correlates following PfSPZ vaccination. 
  • Protection from pathogenic SIV challenge using multigenic DNA vaccines. 
  • Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice. 
  • Protein S-nitrosylation in health and disease: a current perspective. 
  • Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation. 
  • Protein phosphatase inhibitors as potent cytotoxic agents for B-cell CLL in vitro. 
  • Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy. 
  • Protein tyrosine phosphatase-σ regulates hematopoietic stem cell-repopulating capacity. 
  • Pseudo-von Willebrand disease: a mutation in the platelet glycoprotein Ib alpha gene associated with a hyperactive surface receptor. 
  • Pulmonary fibrosis: patterns and perpetrators. 
  • Pulmonary fibrosis: thinking outside of the lung. 
  • Pulmonary hypertension and nitric oxide depletion in sickle cell disease. 
  • Pulmonary marginal zone lymphoma: a single centre experience and review of the SEER database. 
  • Pulmonary, gonadal, and central nervous system status after bone marrow transplantation for sickle cell disease. 
  • Pulse Cyclophosphamide for Steroid-Refractory Chronic Graft-Versus-Host Disease 
  • Pure Red Cell Aplasia in Major ABO-Mismatched Allogeneic Hematopoietic Stem Cell Transplantation Is Associated with Severe Pancytopenia. 
  • Purging of autologous bone marrow for transplantation: the protection and selection of the hematopoietic progenitor cell. 
  • Purification and partial characterization of a human hematopoietic precursor population. 
  • Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway. 
  • Qualified Biolayer Interferometry Avidity Measurements Distinguish the Heterogeneity of Antibody Interactions with Plasmodium falciparum Circumsporozoite Protein Antigens. 
  • Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. 
  • Quality assurance program for peripheral blood mononuclear cell cryopreservation. 
  • Quality control in the flow cytometric measurement of T-lymphocyte subsets: the multicenter AIDS cohort study experience. The Multicenter AIDS Cohort Study Group. 
  • Quality of life domains among non-Hodgkin lymphoma survivors: an integrative literature review. 
  • Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting. 
  • Quantification of total T-cell receptor diversity by flow cytometry and spectratyping. 
  • Quantitating therapeutically relevant T-cell responses to cancer vaccines. 
  • Quantitative analysis demonstrates expansion of SCID-repopulating cells and increased engraftment capacity in human cord blood following ex vivo culture with human brain endothelial cells. 
  • Quantitative analysis of erythrocytes containing fetal hemoglobin (F cells) in children with sickle cell disease. 
  • Quantitative genetic variation in CD19 expression correlates with autoimmunity. 
  • Quantitative modelling to predict candidates for outpatient blood and/or marrow transplantation (BMT) 
  • Quantitative phase microscopy spatial signatures of cancer cells. 
  • RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome. 
  • REPETITIVE IN-VITRO EXPOSURE TO DFP AFFECTS MHC CLASS I AND CLASS II ANTIGEN EXPRESSION 
  • RIPK1 and PGAM5 Control Leishmania Replication through Distinct Mechanisms. 
  • RNA Aptamer Against FXa Synergizes with FXa Catalytic Site Inhibitors to Effectively and Reversibly Anticoagulate Blood in an Ex Vivo Oxygenator Circuit 
  • RNA Interference in Mammals: The Virus Strikes Back. 
  • RNA interference: antiviral defense and genetic tool. 
  • RNA-Mediated Reprogramming of Primary Adult Human Dermal Fibroblasts into c-kit(+) Cardiac Progenitor Cells. 
  • RNA-Sequencing of Isolated Cell Populations Expressing Human APOL1 Risk Variants Reveals Molecular Correlates of Sickle Cell Nephropathy in Zebrafish Podocytes 
  • RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer 
  • RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer. 
  • RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction. 
  • Racial diversity with high nucleated cell counts and CD34 counts achieved in a national network of cord blood banks. 
  • Radiologic and nuclear events: contingency planning for hematologists/oncologists. 
  • Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL). Lederle Cooperative Group. 
  • Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use. 
  • Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia. 
  • Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation. 
  • Rapid Achievement of MR4.5 after Switching from Imatinib (IM) to Nilotinib (NIL) in Patients (Pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP): Preliminary Results from ENESTgoal 
  • Rapid and slow progressors differ by a single MHC class I haplotype in a family of MHC-defined rhesus macaques infected with SIV. 
  • Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. 
  • Rapid changes in light scattering from human polymorphonuclear leukocytes exposed to chemoattractants. Discrete responses correlated with chemotactic and secretory functions. 
  • Rapid, comprehensive analysis of human cytokine mRNA and its application to the study of acute renal allograft rejection. 
  • Rare codons capacitate Kras-driven de novo tumorigenesis. 
  • Rational design of membrane proximal external region lipopeptides containing chemical modifications for HIV-1 vaccination. 
  • Re-engineered CD40 receptor enables potent pharmacological activation of dendritic-cell cancer vaccines in vivo. 
  • Re-evaluating the role of heat-shock protein-peptide interactions in tumour immunity. 
  • Real-world outcomes and management strategies for venetoclax-treated chronic lymphocytic leukemia patients in the United States. 
  • Reassessing the role of astrocytes in ammonia neurotoxicity. 
  • Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse. 
  • Reciprocal control of Forkhead box O 3a and c-Myc via the phosphatidylinositol 3-kinase pathway coordinately regulates p27Kip1 levels. 
  • Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. 
  • Recognition of HLA-A2 mutant and variant target cells by an HLA-A2 allospecific human cytotoxic T lymphocyte line. 
  • Recognition of early mortality in multiple myeloma by a prediction matrix. 
  • Recollective homeostasis and the immune consequences of peritransplant depletional induction therapy. 
  • Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung. 
  • Recombinant Mycobacterium bovis bacillus Calmette-Guerin elicits human immunodeficiency virus type 1 envelope-specific T lymphocytes at mucosal sites. 
  • Recombinant Mycobacterium bovis bacillus Calmette-Guérin vectors prime for strong cellular responses to simian immunodeficiency virus gag in rhesus macaques. 
  • Recombinant adeno-associated virus for muscle directed gene therapy. 
  • Recombinant interferon-alpha2b added to oral cyclophosphamide either as induction or maintenance in treatment-naive follicular lymphoma: final analysis of CALGB 8691. 
  • Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT. 
  • Recovery after allogeneic marrow transplantation: prospective study of predictors of long-term physical and psychosocial functioning. 
  • Recovery from and consequences of severe iatrogenic lymphopenia (induced to treat autoimmune diseases). 
  • Recovery of energy metabolism in rat brain after carbon monoxide hypoxia. 
  • Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. 
  • Redirecting cardiac growth mechanisms for therapeutic regeneration. 
  • Reduced Intensity Conditioning In Children Undergoing Unrelated Umbilical Cord Blood Transplantation for Non-Malignant Diseases: Preliminary Results Demonstrate a High Rate of Engraftment and Low Incidence of Gvhd. 
  • Reduced dose intravenous immunoglobulin does not decrease transplant-related complications in adults given related donor marrow allografts. 
  • Reduced peripheral PGE2 biosynthesis in Plasmodium falciparum malaria occurs through hemozoin-induced suppression of blood mononuclear cell cyclooxygenase-2 gene expression via an interleukin-10-independent mechanism. 
  • Reduced-intensity allogeneic transplantation using alemtuzumab from HLA-matched related, unrelated, or haploidentical related donors for patients with hematologic malignancies. 
  • Reduced-intensity conditioning allogeneic hematopoietic cell transplantation for patients with hematologic malignancies who relapse following autologous transplantation: a multi-institutional prospective study from the Cancer and Leukemia Group B (CALGB trial 100002). 
  • Reduced-intensity conditioning using fludarabine, melphalan and thiotepa for adult patients undergoing haploidentical SCT. 
  • Redundancy renders the glycoprotein 96 receptor scavenger receptor A dispensable for cross priming in vivo. 
  • Refractory lactic acidosis in CD30 positive gastric cancer. 
  • Regenerating functional myocardium: improved performance after skeletal myoblast transplantation. 
  • Regionalization of stem cell transplant procedures into teaching hospitals in United States: are we ready? 
  • Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells. 
  • Regulating regulatory T cells. 
  • Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19. 
  • Regulation of B-cell development by BCAP and CD19 through their binding to phosphoinositide 3-kinase. 
  • Regulation of E2A gene expression in B-lymphocyte development. 
  • Regulation of L-selectin-mediated rolling through receptor dimerization. 
  • Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters. 
  • Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility. 
  • Regulation of T cell receptor delta gene rearrangement by CBF/PEBP2. 
  • Regulation of T cell receptor-alpha gene recombination by transcription. 
  • Regulation of T-cell survival and mitochondrial homeostasis by TSC1. 
  • Regulation of T-helper-cell lineage development by osteopontin: the inside story. 
  • Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure. 
  • Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice. 
  • Regulation of chondrogenesis and chondrocyte differentiation by stress. 
  • Regulation of factor IXa in vitro in human and mouse plasma and in vivo in the mouse. Role of the endothelium and the plasma proteinase inhibitors. 
  • Regulation of fibrinolysis by platelet-released plasminogen activator inhibitor 1: light scattering and ultrastructural examination of lysis of a model platelet-fibrin thrombus. 
  • Regulation of gastric emptying in humans by cholecystokinin. 
  • Regulation of hepatic innate immunity by hepatitis C virus. 
  • Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies. 
  • Regulation of leukocyte adhesion molecule-1 (TQ1, Leu-8) expression and shedding by normal and malignant cells. 
  • Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1. 
  • Regulation of lymphocyte development and activation by the LAT family of adapter proteins. 
  • Regulation of macrophage motility by Irgm1. 
  • Regulation of mast cell survival and function by tuberous sclerosis complex 1. 
  • Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. 
  • Regulation of nuclear Prointerleukin-16 and p27(Kip1) in primary human T lymphocytes. 
  • Regulation of the B cell response to T-dependent antigens by classical pathway complement. 
  • Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. 
  • Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein. 
  • Regulatory B cell (B10 Cell) expansion during Listeria infection governs innate and cellular immune responses in mice. 
  • Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice. 
  • Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis. 
  • Regulatory B cells (B10 cells) have a suppressive role in murine lupus: CD19 and B10 cell deficiency exacerbates systemic autoimmunity. 
  • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. 
  • Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. 
  • Regulatory B10 cell development and function. 
  • Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo. 
  • Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease. 
  • Related umbilical cord blood transplantation in patients with thalassemia and sickle cell disease. 
  • Relationship between event-free survival and overall survival in acute myeloid leukemia: a report from SWOG, HOVON/SAKK, and MRC/NCRI. 
  • Relationship between transferrin saturation and iron stores in the African American and US Caucasian populations: analysis of data from the third National Health and Nutrition Examination Survey. 
  • Relationship of blood monocytes with chronic lymphocytic leukemia aggressiveness and outcomes: a multi-institutional study. 
  • Relationship of the human erythrocyte Wrb antigen to an interaction between glycophorin A and band 3. 
  • Relative survival following response to 7 + 3 versus azacytidine is similar in acute myeloid leukemia and high-risk myelodysplastic syndromes: an analysis of four SWOG studies. 
  • Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice. 
  • Release of DNA from dead and dying lymphocyte and monocyte cell lines in vitro. 
  • Release of tumor cells from bone marrow. 
  • Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. 
  • Replication-defective canarypox (ALVAC) vectors effectively activate anti-human immunodeficiency virus-1 cytotoxic T lymphocytes present in infected patients: implications for antigen-specific immunotherapy. 
  • Reply: the BIM deletion polymorphism cannot account for intrinsic TKI resistance of Chinese individuals with chronic myeloid leukemia. 
  • Report of the Relapsed/Refractory Cohort of SWOG S0919: A Phase 2 Study of Idarubicin and Cytarabine in Combination with Pravastatin for Acute Myelogenous Leukemia 
  • Repression of interleukin-2 mRNA translation in primary human breast carcinoma tumor-infiltrating lymphocytes. 
  • Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor. 
  • Requirement for Ca2+/calmodulin-dependent kinase type IV/Gr in setting the thymocyte selection threshold. 
  • Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytes. 
  • Requirements for T lymphocyte migration in explanted lymph nodes. 
  • Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls. 
  • Rescue of cytotoxic function in the CD8alpha knockout mouse by removal of MHC class II. 
  • Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model. 
  • Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. 
  • Response and toxicity of donor lymphocyte infusions following T-cell depleted non-myeloablative allogeneic hematopoietic SCT from 3-6/6 HLA matched donors. 
  • Response of blood leukocytes to thrombin receptor peptides. 
  • Response to Editorial Reply 
  • Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women. 
  • Results from Enestgoal: A Phase 2 Study of Treatment-Free Remission (TFR) in Patients (pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Who Switched from Imatinib to Nilotinib 
  • Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse. 
  • Results of a Clinical Study of Pevonedistat (Pev),a First-in-Class NEDD8-Activating Enzyme (NAE) Inhibitor, Combined with Azacitidine (Aza) in Older Patients (Pts) with Acute Myeloid Leukemia (AML) 
  • Results of a phase II study of 506U78 in cutaneous T-cell lymphoma and peripheral T-cell lymphoma: CALGB 59901. 
  • Results of allogeneic hematopoietic stem cell transplantation for chronic myelogenous leukemia patients who failed tyrosine kinase inhibitors after developing BCR-ABL1 kinase domain mutations. 
  • Results of minimally toxic nonmyeloablative transplantation in patients with sickle cell anemia and beta-thalassemia. 
  • Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies. 
  • Results of the cord blood transplantation study (COBLT): outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with lysosomal and peroxisomal storage diseases. 
  • Retraction. Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1. 
  • Retraction: Genomic signatures to guide the use of chemotherapeutics. 
  • Retroviral E-DNA: persistence and gene expression in nondividing immune cells. 
  • Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers. 
  • Review of 54 patients with complete DiGeorge anomaly enrolled in protocols for thymus transplantation: outcome of 44 consecutive transplants. 
  • Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). 
  • Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. 
  • Rhesus Macaque Natural CD4 Regulatory T Cells Exhibit Decreased Proliferation But Enhanced Suppression After Pulsing with Sirolimus 
  • Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. 
  • Ribozyme-mediated revision of RNA and DNA. 
  • Risk assessment for hepatic veno-occlusive disease in patients treated with gemtuzumab ozogamicin (Mylotarg (R)) with or without hematopoietic stem cell transplantation. 
  • Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome. 
  • Risk factors for acute GVHD and survival after hematopoietic cell transplantation. 
  • Risk of lymphoproliferative disorders after bone marrow transplantation: a multi-institutional study. 
  • Rod mutations associated with MYH9-related disorders disrupt nonmuscle myosin-IIA assembly. 
  • Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation. 
  • Role for hedgehog pathway in regulating growth and function of invariant NKT cells. 
  • Role of CCR2(+) Monocyte-derived Cells in LPS-induced Acute Lung Injury 
  • Role of Glucose Transporter 1 in Graft-Versus-Host Disease and Graft-Versus-Tumor Effect 
  • Role of Rap1 in promoting sickle red blood cell adhesion to laminin via BCAM/LU. 
  • Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants. 
  • Role of allogeneic transplantation for FLT3/ITD acute myeloid leukemia: outcomes from 133 consecutive newly diagnosed patients from a single institution. 
  • Role of complement activation in obliterative bronchiolitis post-lung transplantation. 
  • Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies. 
  • Role of mast cell leukotrienes in neutrophil recruitment and bacterial clearance in infectious peritonitis. 
  • Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications. 
  • Role of the ABL oncogene tyrosine kinase activity in human leukaemia. 
  • Role of thromboxane A2 in the induction of apoptosis of immature thymocytes by lipopolysaccharide. 
  • Role of transforming growth factor-beta in hematologic malignancies. 
  • Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV. 
  • Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. 
  • Ruxolitinib Used to Treat Hypereosinophilic Syndrome 
  • S-nitrosylation in health and disease. 
  • S-nitrosylation: integrator of cardiovascular performance and oxygen delivery. 
  • S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. 
  • SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery. 
  • SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target. 
  • SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a. 
  • SGN-CD33A (Vadastuximab Talirine) followed by Allogeneic Hematopoietic Stem Cell Transplant (AlloHSCT) Results in Durable Complete Remissions (CRs) in Patients with Acute Myeloid Leukemia (AML) 
  • SGN-CD33A Plus Hypomethylating Agents: A Novel, Well-Tolerated Regimen with High Remission Rate in Frontline Unfit AML 
  • SGN-CD33A: Case Reports of Anti-Leukemic Activity and Bridge to Allogeneic Stem Cell Transplant (SCT) in Patients with Acute Myeloid Leukemia (AML) 
  • SIV-induced instability of the chimpanzee gut microbiome. 
  • SNO-hemoglobin and hypoxic vasodilation. 
  • STAT1 signaling in CD8 T cells is required for their clonal expansion and memory formation following viral infection in vivo. 
  • STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasion. 
  • STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib. 
  • STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis bythe protein kinase inhibitor sorafenib 
  • STAT6-independent production of IL-4 by mast cells. 
  • SWOG S1203: A Randomized Phase III Study of Standard Cytarabine Plus Daunorubicin (7+3) Therapy Versus Idarubicin with High Dose Cytarabine (IA) with or without Vorinostat (IA plus V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML) 
  • Safety and Efficacy of Venetoclax Plus Low-Dose Cytarabine in Treatment-Naive Patients Aged >= 65 Years with Acute Myeloid Leukemia 
  • Safety and Tolerability of Plerixafor in Combination with Cytarabine and Daunorubicin in Patients with Newly Diagnosed Acute Myeloid Leukemia-Preliminary Results From a Phase I Study 
  • Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals. 
  • Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients. 
  • Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group. 
  • Safety of incremental inhaled lipopolysaccharide challenge in humans. 
  • Safety profile of recombinant factor VIIa. 
  • Safety, efficacy, and authorization of eliglustat as a first-line therapy in Gaucher disease type 1 
  • Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines. 
  • Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP. 
  • Searching for transcriptional regulators of Ang II-induced vascular pathology. 
  • Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity. 
  • Second cycle remission achievement with 7+3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials. 
  • Second marrow transplants in patients with aplastic anemia rejecting the first graft: use of a conditioning regimen including cyclophosphamide and antithymocyte globulin. 
  • Secondary allergic T cell responses are regulated by dendritic cell-derived thrombospondin-1 in the setting of allergic eye disease. 
  • Secondary failure of platelet recovery after hematopoietic stem cell transplantation. 
  • Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow. 
  • Secondhand smoke is associated with more frequent hospitalizations in children with sickle cell disease. 
  • Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili. 
  • Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins. 
  • Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB. 
  • Selective expansion of allogeneic regulatory T cells by hepatic stellate cells: role of endotoxin and implications for allograft tolerance. 
  • Selective inhibition of natural killer activity by the monoclonal antibodies OKT10 and VEP10 at the single cell level. 
  • Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. 
  • Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs. 
  • Sensing heart stress. 
  • Sequential contribution of L- and P-selectin to leukocyte rolling in vivo. 
  • Sequential doxorubicin and topotecan in relapsed/refractory aggressive non-Hodgkin's lymphoma: results of CALGB 59906. 
  • Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors. 
  • Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222. 
  • Sequential myeloablative autologous stem cell transplantation and reduced intensity allogeneic hematopoietic cell transplantation is safe and feasible in children, adolescents and young adults with poor-risk refractory or recurrent Hodgkin and non-Hodgkin lymphoma. 
  • Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia. 
  • Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors. 
  • Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity. 
  • Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusion. 
  • Serum proteomic analysis focused on fibrosis in patients with hepatitis C virus infection. 
  • Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells. 
  • Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44. 
  • Severely impaired B lymphocyte proliferation, survival, and induction of the c-Myc:Cullin 1 ubiquitin ligase pathway resulting from CD22 deficiency on the C57BL/6 genetic background. 
  • Sevuparin binds to multiple adhesive ligands and reduces sickle red blood cell-induced vaso-occlusion. 
  • Shared Decision-Making in Hematopoietic Stem Cell Transplantation for Sickle Cell Disease. 
  • ShcA and c-Abl provide a new signaling axis regulating beta-selection 
  • Short Course of Bendamustine and Rituximab Followed By 90Y-Ibritumomab Tiuxetan in Patients with Chemotherapy-Naive Follicular Lymphoma (FOL-BRITe): Final Report of Response Rates and Progression Free Survival 
  • Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation. 
  • Signaling by the TNF Receptor Superfamily and T Cell Homeostasis 
  • Similar CD19 dysregulation in two autoantibody-associated autoimmune diseases suggests a shared mechanism of B-cell tolerance loss. 
  • Simultaneous Measurement of Cerebral Blood Flow and Arterial Transit Time for Sickle Cell Disease 
  • Simultaneous detection of eight analytes in human serum by two commercially available platforms for multiplex cytokine analysis. 
  • Simultaneous functional photoacoustic and ultrasonic endoscopy of internal organs in vivo. 
  • Single Donor 4/6 Matched Banked Unrelated Cord Blood Is An Effective Graft Source for Children Undergoing Myeloablative Transplantation for Malignant and Nonmalignant Disorders: Single Center Analysis of 318 Patients 
  • Single agent bortezomib in the treatment of relapsed and refractory Hodgkin lymphoma: cancer and leukemia Group B protocol 50206. 
  • Single center experience of unrelated umbilical cord blood transplantation (UCBDT) for acute myeloid leukemia (AML) in 97 pediatric patients: Impact of disease status and cytoreductive regimen 
  • Single-Agent Clofarabine Produces Durable Remissions in Patients with Acute Myelogenous Leukemia (AML) Who Are >= 70, Have Intermediate or Unfavorable Cytogenetics, Antecedent Hematological Disorders (AHD), or 2 or More Unfavorable Prognostic Factors 
  • Sirolimus Inhibits Proliferation but Enhances Suppressive Activity of Rhesus Macaque Natural CD4 Regulatory T Cells 
  • Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin. 
  • Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair. 
  • Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver. 
  • Smoothened is a master regulator of adult liver repair. 
  • Soluble B7-H1: Differences in production between dendritic cells and T cells 
  • Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells. 
  • Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia. 
  • Specific association of retroviral envelope protein, p15E, with human cell surfaces. 
  • Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation. 
  • Spliceosomal component Sf3b1 is essential for hematopoietic differentiation in zebrafish. 
  • Spontaneous delta- to beta-globin switching in K562 human leukemia cells. 
  • Spontaneous formation of germinal centers in autoimmune mice. 
  • Stability of Th1 and Th2 populations. 
  • Stable Expression of Lentiviral Antigens by Quality-Controlled Recombinant Mycobacterium bovis BCG Vectors. 
  • Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication. 
  • Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia. 
  • Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation. 
  • Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process. 
  • State of the art: Reproduction and pregnancy in rheumatic diseases. 
  • Statistical mixture modeling for cell subtype identification in flow cytometry 
  • Status of high-dose chemotherapy for breast cancer: a review. 
  • Stem Cell Transplantation and Informatics: Current Considerations 
  • Stem cell isolation. 
  • Stem cells for the ischaemic heart. 
  • Stem-cell transplantation for the treatment of advanced solid tumors. 
  • Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing. 
  • Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice. 
  • Straight talk with...Victor Dzau. Interview by Roxanne Khamsi. 
  • Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses. 
  • Strategies to circumvent humoral immunity to adeno-associated viral vectors. 
  • Strength through Organization: Classifying Antibody Activity against EBOV. 
  • Streptokinase promotes development of dipeptidyl peptidase IV (CD26) autoantibodies after fibrinolytic therapy in myocardial infarction patients. 
  • Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones. 
  • Stromal heparan sulfate differentiates neuroblasts to suppress neuroblastoma growth. 
  • Structural analysis of HLA-A2 antigen from immunoselected mutant 8.6.1: further definition of an HLA-A2-specific serological determinant. 
  • Structural organization of the human MS4A gene cluster on Chromosome 11q12. 
  • Structural rearrangements in the transmembrane glycoprotein after receptor binding. 
  • Structural requirements regulate endoproteolytic release of the L-selectin (CD62L) adhesion receptor from the cell surface of leukocytes. 
  • Subpopulations of common acute lymphoblastic leukemia antigen-positive lymphoid cells in normal bone marrow identified by hematopoietic differentiation antigens. 
  • Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis. 
  • Subtype C gp140 Vaccine Boosts Immune Responses Primed by the South African AIDS Vaccine Initiative DNA-C2 and MVA-C HIV Vaccines after More than a 2-Year Gap. 
  • Successful Engraftment of Donor Umbilical Cord Blood (UCB) Cells after Co-Transplantation of Nicord (R) (Ex Vivo Expanded UCB Progenitor Cells with Nicotinamide) and a Second Unmanipulated Cord Blood Unit after Myeloablative Chemotherapy in Pediatric Patients with Severe Sickle Cell Disease 
  • Successful allogeneic engraftment of mismatched unrelated cord blood following a nonmyeloablative preparative regimen. 
  • Successful immune reconstitution decreases leukemic relapse and improves survival in recipients of unrelated cord blood transplantation. 
  • Successful management of autoimmune hemolytic anemia with steroid, IVIg and plasmapheresis in a haploidentical transplant recipient 
  • Successful treatment with apixaban of sinus venous thrombosis due to pegylated asparaginase in a young adult with T cell acute lymphoblastic leukemia: case report and review of management. 
  • Successful tumour immunotherapy: possible role of antibodies to anti-inflammatory factors produced by neoplasms. 
  • Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4+ T lymphocytes. 
  • Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system. 
  • Superoxide production by digitonin-stimulated guinea pig granulocytes. The effects of N-ethyl maleimide, divalent cations; and glycolytic and mitochondrial inhibitors on the activation of the superoxide generating system. 
  • Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. 
  • Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia. 
  • Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease. 
  • Suppression of human interferon-gamma production by a 17 amino acid peptide homologous to the transmembrane envelope protein of retroviruses: evidence for a primary role played by monocytes. 
  • Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex. 
  • Suppression of the respiratory burst of human monocytes by a synthetic peptide homologous to envelope proteins of human and animal retroviruses. 
  • Supramolecular peptide vaccines: tuning adaptive immunity. 
  • Surface CD5 Protein Risk Stratifies Chronic Lymphocytic Leukemia 
  • Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection. 
  • Surface plasmon resonance measurements of plasma antibody avidity during primary and secondary responses to anthrax protective antigen 
  • Surface plasmon resonance measurements of plasma antibody avidity during primary and secondary responses to anthrax protective antigen. 
  • Surfactant protein A modulates induction of regulatory T cells via TGF-β. 
  • Surrogate markers of response to cancer immunotherapy. 
  • Survival and Functional Outcomes in Boys with Cerebral Adrenoleukodystrophy with and without Hematopoietic Stem Cell Transplantation. 
  • Survival of acute myeloid leukemia cells requires PI3 kinase activation. 
  • Symptom Burden, Quality of Life, and Distress in Acute Myeloid Leukemia Patients Receiving Induction Chemotherapy: Results of a Prospective Electronic Patient-Reported Outcomes Study 
  • Synergistic control of T cell activation, regulatory T cell function, and autoimmunity by Diacylglycerol Kinases alpha and zeta 
  • Synergistic control of T cell development by Diacylglycerol kinase alpha and zeta 
  • Synergistic role of idacylglycerol kinases alpha and zeta in T cell development and self-tolerance 
  • Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction. 
  • Synthetic peptide in mineral oil adjuvant elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes in rhesus monkeys. 
  • Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of neutralizing antibodies in rhesus monkeys. 
  • Systemic Sclerosis as an Indication for Autologous Hematopoietic Cell Transplantation: Position Statement from the American Society for Blood and Marrow Transplantation. 
  • Systems biology of vaccination for seasonal influenza in humans. 
  • T CELL POSITIVE AND B CELL NEGATIVE FCXM WITH PRONASE TREATED DONOR CELLS OBSERVED IN AN HIV INFECTED PATIENT. 
  • T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms. 
  • T cell assays and MIATA: the essential minimum for maximum impact. 
  • T cell development: better living through chromatin. 
  • T cell metabolic fitness in antitumor immunity 
  • T cell metabolic fitness in antitumor immunity. 
  • T cell receptor excision circle assessment of thymopoiesis in aging mice. 
  • T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity. 
  • T cell-mediated elimination of B7.2 transgenic B cells. 
  • T lymphocyte ontogeny in adenosine deaminase-deficient severe combined immune deficiency after treatment with polyethylene glycol-modified adenosine deaminase. 
  • T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates. 
  • T-Cell recovery in adults and children following umbilical cord blood transplantation. 
  • T-cell exhaustion: characteristics, causes and conversion. 
  • T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction. 
  • T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells. 
  • TARGETING NEUROINFLAMMATION WITH HUMAN UMBILICAL CORD TISSUE-DERIVED MESENCHYMAL STROMAL CELLS 
  • TCF1 links GIPR signaling to the control of beta cell function and survival. 
  • TGF-beta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis. 
  • TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. 
  • TLR4 signaling attenuates ongoing allergic inflammation. 
  • TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder. 
  • TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44. 
  • TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the Cutaneous Lymphoma Task Force of the European Organization of Research and Treatment of Cancer (EORTC). 
  • TOWARDS A MECHANISM-BASED POTENCY ASSAY FOR CORD BLOOD UNITS IN TREATMENT OF HYPOXIC-ISCHEMIC BRAIN DAMAGE 
  • TRPA1 is a major oxidant sensor in murine airway sensory neurons. 
  • TSC1 is critical for iNKT-cell terminal maturation and controls iNKT-1/17 balance 
  • TUMOR-INDUCED IMMUNOSUPPRESSION - INHIBITION OF INTERLEUKIN-2 PRODUCTION BY TUMOR-CELL PRODUCTS AND A P15E-RELATED PEPTIDE 
  • Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation. 
  • Tacrolimus and mycophenolate mofetil after nonmyeloablative matched-sibling donor allogeneic stem-cell transplantations conditioned with fludarabine and low-dose total body irradiation. 
  • Tandem bispecific broadly neutralizing antibody — a novel approach to HIV-1 treatment 
  • Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. 
  • Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis. 
  • Targeted genetic repair: an emerging approach to genetic therapy. 
  • Targeted inhibition of V(D)J recombination by a histone methyltransferase. 
  • Targeted inhibition of VEGF receptor 2: an update on ramucirumab. 
  • Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice. 
  • Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. 
  • Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature. 
  • Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection 
  • Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. 
  • Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. 
  • Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. 
  • Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis. 
  • Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression. 
  • Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome. 
  • Targeting the local tumor microenvironment with vaccinia virus expressing B7.1 for the treatment of melanoma. 
  • Teaching advanced flow cytometry in Africa: 10 years of lessons learned. 
  • Temporal correlation of antibody responses to different epitopes of the human La autoantigen. 
  • Temporal dynamics of Wnt-dependent transcriptome reveals an oncogenic Wnt/MYC/ribosome axis. 
  • Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy. 
  • Terminal deoxynucleotidyl transferases from elasmobranchs reveal structural conservation within vertebrates. 
  • Th17 cells are long lived and retain a stem cell-like molecular signature. 
  • The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. 
  • The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha. 
  • The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. 
  • The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules. 
  • The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity. 
  • The CD19-CD21 signal transduction complex of B lymphocytes regulates the balance between health and autoimmune disease: systemic sclerosis as a model system. 
  • The CD28 signaling pathway regulates glucose metabolism. 
  • The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy. 
  • The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis. 
  • The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. 
  • The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs. 
  • The Complex Relationship Between Sickle Cell Disease and Depression 
  • The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration. 
  • The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia. 
  • The DRiP hypothesis decennial: support, controversy, refinement and extension. 
  • The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression. 
  • The First B-Cell Tolerance Checkpoint in Mice and Humans: Control by AID 
  • The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflammatory cytokine production and prevents endotoxemia. 
  • The Immune Landscape of Cancer 
  • The Immune Tolerance Network at 10 years: tolerance research at the bedside. 
  • The Impact of Graft-versus-Host Disease on the Relapse Rate in Patients with Lymphoma Depends on the Histological Subtype and the Intensity of the Conditioning Regimen. 
  • The Inab phenotype: characterization of the membrane protein and complement regulatory defect. 
  • The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors. 
  • The Metabolic Signature of CLL: Enhanced Glucose Metabolism in A Subset of High-Risk CLL Patients 
  • The Microbiome and Hematopoietic Cell Transplantation: Past, Present, and Future. 
  • The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. 
  • The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. 
  • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. 
  • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. 
  • The Necroptosis Adaptor RIPK3 Promotes Injury-Induced Cytokine Expression and Tissue Repair 
  • The Novel, Investigational NEDD8-Activating Enzyme Inhibitor MLN4924 In Adult Patients with Acute Myeloid Leukemia (AML) or High-Grade Myelodysplastic Syndromes (MDS): A Phase 1 Study 
  • The PEPvIII-KLH (CDX-110) vaccine in glioblastoma multiforme patients. 
  • The Role of Surface Immunoglobulin Isotype in Chronic Lymphocytic Leukemia Disease Biology and Clinical Outcome 
  • The Smads: transcriptional regulation and mouse models. 
  • The Stimulatory Potency of T Cell Antigens Is Influenced by the Formation of the Immunological Synapse 
  • The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice. 
  • The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis. 
  • The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels. 
  • The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens 
  • The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules. 
  • The annual ASCI meeting: does nostalgia have a future? 
  • The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes. 
  • The antigenic complex in HIT binds to B cells via complement and complement receptor 2 (CD21). 
  • The benefits of restraint: a pivotal role for IL-13 in hepatic glucose homeostasis. 
  • The binding site of human adenosine deaminase for CD26/Dipeptidyl peptidase IV: the Arg142Gln mutation impairs binding to cd26 but does not cause immune deficiency. 
  • The biochemistry of somatic hypermutation. 
  • The biological activity of a liposomal complete core lipopolysaccharide vaccine. 
  • The biology of human lymphoid malignancies revealed by gene expression profiling. 
  • The blood nucleome in the pathogenesis of SLE. 
  • The bridge between dendritic cells and asthma. 
  • The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19. 
  • The calm after the cytokine storm: lessons from the TGN1412 trial. 
  • The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases. 
  • The challenges of checkpoint inhibition in the treatment of multiple myeloma. 
  • The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression. 
  • The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl. 
  • The commercialism of academic research 
  • The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge. 
  • The contribution of autophagy to lymphocyte survival and homeostasis. 
  • The current epidemiology and clinical decisions surrounding acute respiratory infections 
  • The current epidemiology and clinical decisions surrounding acute respiratory infections. 
  • The cutaneous lymphocyte antigen is an essential component of the L-selectin ligand induced on human vascular endothelial cells. 
  • The cutaneous reverse Arthus reaction requires intercellular adhesion molecule 1 and L-selectin expression. 
  • The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 
  • The danger of sex and death in Scarf1(-/-) autoimmune mice. 
  • The development and function of memory regulatory T cells after acute viral infections. 
  • The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. 
  • The dual role of IL-10. 
  • The effect of AZT on in vitro lymphokine-activated killer (LAK) activity in human immunodeficiency virus type-1 (HIV-1) infected individuals. 
  • The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients. 
  • The effect of fibrin-stabilizing factor on the subunit structure of human fibrin. 
  • The effects of IL-1, IL-2, and tumor necrosis factor on polymorphonuclear leukocyte Fc gamma receptor-mediated phagocytosis. IL-2 down-regulates the effect of tumor necrosis factor. 
  • The effects of chronic opiates pain therapy in sickle cell anemia 
  • The evolution of the evidence-based review: evaluating the science enhances the art of medicine--statement of the Steering Committee for Evidence-Based Reviews of the American Society for Blood and Marrow Transplantation. 
  • The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation. 
  • The expression of HMGB1 on microparticles released during cell activation and cell death in vitro and in vivo. 
  • The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. 
  • The extracellular matrix protein mindin serves as an integrin ligand and is critical for inflammatory cell recruitment. 
  • The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus–induced microRNAs 
  • The final touches make perfect the peptide-MHC class I repertoire. 
  • The fine specificity of anti-La antibodies induced in mice by immunization with recombinant human La autoantigen. 
  • The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. 
  • The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells. 
  • The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation. 
  • The gamma delta T cell receptor. 
  • The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. 
  • The great balancing act: regulation and fate of antiviral T-cell interactions. 
  • The gut connectome: making sense of what you eat. 
  • The host defense peptide cathelicidin is required for NK cell-mediated suppression of tumor growth. 
  • The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants. 
  • The human thymic microenvironment during organ culture. 
  • The human thymic microenvironment. 
  • The human thymic microenvironment. Phenotypic characterization of Hassall's bodies with the use of monoclonal antibodies. 
  • The human thymic microenvironment: cortical thymic epithelium is an antigenically distinct region of the thymic microenvironment. 
  • The human thymus. A chimeric organ comprised of central and peripheral lymphoid components. 
  • The human thymus. A chimeric organ comprised of central and peripheral lymphoid components. 
  • The immune response during acute HIV-1 infection: clues for vaccine development. 
  • The imperative to invest in science has never been greater. 
  • The imperative to invest in science has never been greater. 
  • The in vivo balance between B cell clonal expansion and elimination is regulated by CD95 both on B cells and in their micro-environment. 
  • The inextricable role of the kidney in hypertension. 
  • The influence of lipofectin on the in vitro stimulation of murine spleen cells by bacterial DNA and plasmid DNA vectors. 
  • The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. 
  • The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. 
  • The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells. 
  • The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors. 
  • The junctophilin family of proteins: from bench to bedside. 
  • The level of IgE produced by a B cell is regulated by norepinephrine in a p38 MAPK- and CD23-dependent manner. 
  • The liver kinase B1 is a central regulator of T cell development, activation, and metabolism. 
  • The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-kappaB-independent pathway. 
  • The mast cell activator Compound 48/80 is a potent adjuvant for intradermally-administered anthrax protective antigen 
  • The metabolic life and times of a T-cell. 
  • The miscible pool and turnover rate of hydrocortisone in man. 
  • The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus. 
  • The mitochondrial targeting chaperone 14-3-3ε regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity. 
  • The molecular basis of class II MHC allelic control of T cell responses. 
  • The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domain. 
  • The mouse CD7 gene: identification of a new element common to the human CD7 and mouse Thy-1 promoters. 
  • The mouse Cd83 gene: structure, domain organization, and chromosome localization. 
  • The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity 
  • The multiple causes of human SCID. 
  • The n-hexane and chloroform fractions of Piper betle L. trigger different arms of immune responses in BALB/c mice and exhibit antifilarial activity against human lymphatic filarid Brugia malayi. 
  • The natural history of children with severe combined immunodeficiency: baseline features of the first fifty patients of the primary immune deficiency treatment consortium prospective study 6901. 
  • The nature of immune responses to urinary tract infections. 
  • The non-haematopoietic biological effects of erythropoietin. 
  • The other physician-scientist problem: where have all the young girls gone? 
  • The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first and second complete remission. 
  • The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice. 
  • The physiological disposition and metabolic fate of hydrocortisone in man. 
  • The price of drugs for chronic myeloid leukemia (CML) is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts. 
  • The promoter of human T-cell leukemia virus type-I is repressed by the immediate-early gene region of human cytomegalovirus in primary blood lymphocytes. 
  • The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure. 
  • The quest for an antibody-based HIV vaccine. 
  • The rapid and large scale separation of peritoneal macrophages. 
  • The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid. 
  • The relationship between cardiac endothelium and fibroblasts: it's complicated. 
  • The relationship of opiate analgesia to quality of life in an adult sickle cell population 
  • The relevance of information generated by in vitro experimental models to clinical doxorubicin cardiotoxicity. 
  • The renin-angiotensin system: it's all in your head. 
  • The requirement of reversible cysteine sulfenic acid formation for T cell activation and function. 
  • The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up. 
  • The role of EVI1 in myeloid malignancies. 
  • The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases. 
  • The role of IL-13 in the generation of dendritic cells in vitro. 
  • The role of MTJ-1 in cell surface translocation of GRP78, a receptor for alpha 2-macroglobulin-dependent signaling. 
  • The role of adhesion molecules in human leukocyte attachment to porcine vascular endothelium: implications for xenotransplantation. 
  • The role of antibodies in HIV vaccines. 
  • The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants. 
  • The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes. 
  • The role of biomaterials in stem cell differentiation: applications in the musculoskeletal system. 
  • The role of complement in inflammation and phagocytosis. 
  • The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of myelodysplastic syndromes: an evidence-based review. 
  • The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of diffuse large B cell lymphoma: update of the 2001 evidence-based review. 
  • The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of follicular lymphoma: an evidence-based review. 
  • The role of glutathione reductase in maintaining human granulocyte function and sensitivity to exogenous H2O2. 
  • The role of interferon-β in the treatment of multiple sclerosis and experimental autoimmune encephalomyelitis - in the perspective of inflammasomes. 
  • The role of leukocyte adhesion molecules in cellular interactions: implications for the pathogenesis of inflammatory synovitis. 
  • The role of mTORC1 on regulating tissue resident macrophage homeostasis 
  • The role of mast cells in host defense and their subversion by bacterial pathogens. 
  • The role of natural regulatory T cells in infection. 
  • The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine. 
  • The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes. 
  • The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection. 
  • The role of transmethylation reactions in regulating the binding of BCG-activated murine macrophages to neoplastic target cells. 
  • The role of tuberous sclerosis complex 1 in regulating innate immunity. 
  • The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches. 
  • The roles of alpha IIb beta 3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation. 
  • The roles of orphan nuclear receptors in the development and function of the immune system. 
  • The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus. 
  • The sickle cell disease implementation consortium: Translating evidence-based guidelines into practice for sickle cell disease. 
  • The sooner the better: Our laboratory experience with chorionic villus sampling (CVS) HLA typing prior to HSCT 
  • The structural basis of repertoire shift in an immune response to phosphocholine. 
  • The tetraspanin CD81 regulates the expression of CD19 during B cell development in a postendoplasmic reticulum compartment. 
  • The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. 
  • The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction. 
  • The type III TGF-beta receptor suppresses breast cancer progression. 
  • The use of high-dose cyclophosphamide, carmustine, and thiotepa plus autologous hematopoietic stem cell transplantation as consolidation therapy for high-risk primary breast cancer after primary surgery or neoadjuvant chemotherapy. 
  • The yin yang of bacterial polysaccharides: lessons learned from B. fragilis PSA. 
  • The zinc finger transcription factor ZFX is required for maintaining the tumorigenic potential of glioblastoma stem cells. 
  • Therapeutic CD154 antibody for lupus: promise for the future? 
  • Therapeutic potential of β-arrestin- and G protein-biased agonists. 
  • Therapy with bortezomib plus lenalidomide for relapsed/refractory mantle cell lymphoma: final results of a phase II trial (CALGB 50501). 
  • Therapy with mycophenolate mofetil for refractory acute and chronic GVHD. 
  • Thermic effect of food in lean and obese men. 
  • Thinking outside the gate: single-cell assessments in multiple dimensions. 
  • Three Factor Prothrombin Complex Concentrates in Cardiac Surgery: A Novel Algorithmic Approach to Perioperative Bleeding 
  • Three is better than one: Pre-ligand receptor assembly in the regulation of TNF receptor signaling 
  • Thrombin enhances monocyte secretion of tumor necrosis factor and interleukin-1 beta by two distinct mechanisms. 
  • Thrombocytopenia in association with a wandering spleen. 
  • Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand - Reply 
  • Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. 
  • Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection. 
  • Thymic expression of the transcription factor Nur77 rescues the T cell but not the B cell abnormality of gld/gld mice 
  • Thymic involution and immune reconstitution. 
  • Thymic rejuvenation and aging. 
  • Thymoma-associated immunodeficiency: a syndrome characterized by severe alterations in NK, T and B-cells and progressive increase in naïve CD8+ T Cells. 
  • Thymus transplantation in complete DiGeorge syndrome: immunologic and safety evaluations in 12 patients. 
  • Thymus transplantation. 
  • Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy. 
  • Ticlopidine-associated ADAMTS13 activity deficient thrombotic thrombocytopenic purpura in 22 persons in Japan: a report from the Southern Network on Adverse Reactions (SONAR). 
  • Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling. 
  • Tie2(+) bone marrow endothelial cells regulate hematopoietic stem cell regeneration following radiation injury. 
  • Time Sensitive Parameters of Immune Reconstitution Measured Between Day 100 and 1 Year Predict Survival After Unrelated Cord Blood Transplant (UCBT): The Dynamic Impact of Dendritic Cells, Tregs, and Thymic Recovery 
  • Tissue factor in experimental acute lung injury 
  • Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells. 
  • Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. 
  • Tissue plasminogen activator (tPA) signal sequence enhances immunogenicity of MVA-based vaccine against tuberculosis. 
  • Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice. 
  • Tolerance induced by apoptotic antigen-coupled leukocytes is induced by PD-L1+ and IL-10-producing splenic macrophages and maintained by T regulatory cells. 
  • Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells. 
  • Toll-like receptors in the pathogenesis of human disease. 
  • Total colony-forming units are a strong, independent predictor of neutrophil and platelet engraftment after unrelated umbilical cord blood transplantation: a single-center analysis of 435 cord blood transplants. 
  • Toward better representations of sound with cochlear implants. 
  • Toxicities and outcomes of 616 ibrutinib-treated patients in the United States: a real-world analysis. 
  • Toxicity, pharmacology and feasibility of administration of PEG-L-asparaginase as consolidation therapy in patients undergoing bone marrow transplantation for acute lymphoblastic leukemia. 
  • Toxin-based targeted therapy for malignant brain tumors. 
  • Tradition, tradition. 
  • Transcript Expression, Intron Retention, and RNA Editing Are Conserved in Human Platelets over a 4 Year Period 
  • Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway. 
  • Transcriptional down-regulation of tumor necrosis factor-alpha gene expression by a synthetic peptide homologous to retroviral envelope protein. 
  • Transcriptional regulation of T lymphocyte development and function. 
  • Transcriptional regulatory functions of heterogeneous nuclear ribonucleoprotein-U and -A/B in endotoxin-mediated macrophage expression of osteopontin. 
  • Transepithelial transport of maternal antibody: purification of IgG receptor from newborn rat intestine. 
  • Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression. 
  • Transformation in Pre-Treatment Presentations of Gaucher Disease during the First Two Decades of Imiglucerase Enzyme Replacement Therapy: A Report from the International Collaborative Gaucher Group Gaucher Registry 
  • Transforming properties of the P185, P210 and P230 variants of BCR/ABL in primary mouse bone marrow. 
  • Transfusion Dependence and Use of Hospice Among Medicare Beneficiaries with Leukemia 
  • Transfusion and alloimmunization in sickle cell disease. The Cooperative Study of Sickle Cell Disease. 
  • Transfusion dependence, use of hospice services, and quality of end-of-life care in leukemia. 
  • Transgenic Expression of the Viral FLIP MC159 Causes lpr/gld-Like Lymphoproliferation and Autoimmunity 
  • Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy. 
  • Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance. 
  • Transmembrane adaptor proteins: organizers of immunoreceptor signalling. 
  • Transmission of human immunodeficiency virus to sexual partners of hemophiliacs. 
  • Transplantation Following Myeloablative Cytoreduction Results in Excellent Survival, Long-Term Engraftment, and Donor Chimerism in Children with Chronic Granulomatous Disease Across Donor and Graft Sources 
  • Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. 
  • Transplantation of CD34+ hematopoietic progenitor cells. 
  • Transplantation of CD34+ marrow and/or PBPCS into breast cancer patients following high-dose chemotherapy 
  • Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization. 
  • Transplantation of adult and pediatric cancer patients with cord blood progenitors expanded ex vivo 
  • Transplantation of ex vivo expanded cord blood 
  • Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial. 
  • Transplantation of hematopoietic stem cells in human severe combined immunodeficiency: longterm outcomes. 
  • Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice. 
  • Transplantation tolerance: a look at the nonhuman primate literature in the light of modern tolerance theories. 
  • Transplantation: Integrating the concepts of innate and acquired immunity with translational trials 
  • Transport properties of pancreatic cancer describe gemcitabine delivery and response. 
  • Treatment of Relapsed or Refractory Acute Lymphoblastic Leukemia in Real-World US Practices 
  • Treatment of menorrhagia in women undergoing hematopoietic stem cell transplantation. 
  • Treatment of murine peritoneal macrophages with bacterial lipopolysaccharide alters expression of c-fos and c-myc oncogenes. 
  • Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL. 
  • Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. 
  • Trends in primary central nervous system lymphoma incidence and survival in the U.S. 
  • Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F. 
  • Tuberculous meningitis: a roadmap for advancing basic and translational research. 
  • Tumor necrosis factor induces tissue factor-like activity in human leukemia cell line U937 and peripheral blood monocytes. 
  • Tumor potential in rat wounds after short- and long-term administration of platelet-rich plasma: an update. 
  • Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma. 
  • Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning. 
  • Tumor-targeted, systemic delivery of therapeutic viral vectors using hitchhiking on antigen-specific T cells. 
  • Twenty-five-year follow-up among survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. 
  • Two Sides of the Same Coin: Pediatric-Onset and Adult-Onset Common Variable Immune Deficiency. 
  • Two forms of NF-kappa B1 (p105/p50) in murine macrophages: differential regulation by lipopolysaccharide, interleukin-2, and interferon-gamma. 
  • Two new polymorphisms but no mutations of the KIT gene in patients with myelodysplasia at positions corresponding to human FMS and murine W locus mutational hot spots 
  • Type 1 angiotensin receptors on macrophages ameliorate IL-1 receptor-mediated kidney fibrosis. 
  • Type 17 CD8+ T cells display enhanced antitumor immunity. 
  • Type 2 alveolar cells are stem cells in adult lung. 
  • Type I IFN signaling on both B and CD4 T cells is required for protective antibody response to adenovirus. 
  • Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment. 
  • Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma. 
  • Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2. 
  • Tyrosine phosphorylation-independent regulation of lipopolysaccharide-mediated response by the transmembrane adaptor protein LAB. 
  • Ubiquitination of Innate Immune Regulator TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex. 
  • Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia. 
  • Ultrastructural analysis of granulocyte inclusions in genetically confirmed MYH9-related disorders. 
  • Umbilical Cord Blood (UCB) Transplantation in Children with Acute Leukemia: Impact of Conditioning Regimen on Transplant Outcomes 
  • Umbilical Cord Blood Transplantation for Cartilage Hair Hypoplasia: A Single Center Experience Demonstrates Excellent Outcomes Using Myeloablative Preparative Regimens 
  • Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment. 
  • Umbilical cord blood transplantation for children with thalassemia and sickle cell disease. 
  • Umbilical cord blood transplantation for non-malignant diseases. 
  • Under pressure: the search for the essential mechanisms of hypertension. 
  • Underlying potential: cellular and molecular determinants of adult liver repair. 
  • Understanding patterns and correlates of daily pain using the Sickle cell disease Mobile Application to Record Symptoms via Technology (SMART). 
  • Unique sensitivity of Hb Zürich to oxidative injury by phenazopyridine: reversal of the effects by elevating carboxyhemoglobin levels in vivo and in vitro. 
  • Unrelated Umbilical Cord Blood Transplantation From A Single 4/6 Matched Unit is an Effective Therapy for Children With Malignant and Non-Malignant Diagnoses: Good Survival, Low Graft Failure and Graft-vs-Host Disease in a Single Center Analysis of 314 Patients 
  • Unrelated Umbilical Cord Blood Transplantation for Pediatric Hemophagocytic Lymphohistiocytosis 
  • Unrelated donor cord blood transplantation for children with severe sickle cell disease: results of one cohort from the phase II study from the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). 
  • Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes. 
  • Unrelated umbilical cord blood stem cell transplant after failure of haploidentical or matched unrelated donor hematopoietic stem cell transplant. 
  • Untying the Gordian knot: policies, practices, and ethical issues related to banking of umbilical cord blood. 
  • Up-regulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin. 
  • Updated survival analysis of two sequential prospective trials of R-MACLO-IVAM followed by maintenance for newly diagnosed mantle cell lymphoma. 
  • Urinary albumin excretion is associated with pulmonary hypertension in sickle cell disease: potential role of soluble fms-like tyrosine kinase-1 
  • Usability and Feasibility of an mHealth Intervention for Monitoring and Managing Pain Symptoms in Sickle Cell Disease: The Sickle Cell Disease Mobile Application to Record Symptoms via Technology (SMART). 
  • Use of C6-deficient rats to evaluate the mechanism of hyperacute rejection of discordant cardiac xenografts. 
  • Use of Cyclosporine Is Associated with the Increase in Pre-Engraftment Syndrome After Myeloablative Dual Cord Blood Transplantation 
  • Use of ED and hospital services for patients with acute leukemia after induction therapy: one year follow-up. 
  • Use of Mobile Technology to Monitor Pain and Reduce Outpatient, Emergency Department (ED), and Hospital Visits for Sickle Cell Pain Crisis 
  • Use of allograft biopsies to assess thymopoiesis after thymus transplantation. 
  • Use of intravenous gamma-globulin in antibody immunodeficiency: results of a multicenter controlled trial. 
  • Use of serum-free media to minimize apoptosis of chronic lymphocytic leukemia cells during in vitro culture. 
  • Use of thymic grafts or thymic factors to augment immunologic recovery after bone marrow transplantation: brief report with 2 to 12 years' follow-up. 
  • Utility of Autopsy among Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients: One Last Chance to Learn? 
  • Utility of obtaining blood cultures in febrile neutropenic patients undergoing bone marrow transplantation. 
  • Utility of peripheral blood dual color, double fusion fluorescent in situ hybridization for BCR/ABL fusion to assess cytogenetic remission status in chronic myeloid leukemia. 
  • V(D)J hypermutation and receptor revision: coloring outside the lines. 
  • V(D)J recombination becomes accessible. 
  • VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression. 
  • VEGF-targeted cancer therapy strategies: current progress, hurdles and future prospects. 
  • Vaccination establishes clonal relatives of germinal center T cells in the blood of humans. 
  • Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor efficiently primes CTL responses, but is insufficient to overcome tolerance to a model tumor/self antigen. 
  • Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2. 
  • Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages 
  • Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages. 
  • Vadastuximab Talirine Monotherapy in Older Patients with Treatment Naive CD33-Positive Acute Myeloid Leukemia (AML) 
  • Vadastuximab Talirine Plus Hypomethylating Agents: A Well-Tolerated Regimen with High Remission Rate in Frontline Older Patients with Acute Myeloid Leukemia (AML) 
  • Variable HLA expression on deceased donor lymphocytes: Not all crossmatches are created equal. 
  • Variable phenotypic expression of mutations in genes of the immune system. 
  • Variation in Serial TCD Velocity Measurements in the TCD with Transfusions Changing to Hydroxyurea (TWiTCH) Trial 
  • Vascular endothelial cells produce soluble factors that mediate the recovery of human hematopoietic stem cells after radiation injury. 
  • Vascular endothelial growth factor inhibition is not an effective therapeutic strategy for relapsed or refractory multiple myeloma: a phase 2 study of pazopanib (GW786034). 
  • Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies. 
  • Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II. 
  • Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias. Acute regulation of CFTR trafficking in an intact epithelium. 
  • Venetoclax as Targeted Therapy for Relapsed/Refractory Multiple Myeloma 
  • Venetoclax for patients with chronic lymphocytic leukemia who progressed during or after idelalisib therapy 
  • Vertical T cell immunodominance and epitope entropy determine HIV-1 escape 
  • Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced. 
  • Viral Infection "Interferes" with Glucose Tolerance. 
  • Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases. 
  • Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells. 
  • Viral and cellular microRNAs as determinants of viral pathogenesis and immunity. 
  • Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines. 
  • Viremia control despite escape from a rapid and potent autologous neutralizing antibody response after therapy cessation in an HIV-1-infected individual. 
  • Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide. 
  • Vision of correction for classic homocystinuria. 
  • Von Willebrand Factor to Prevent Postpartum Hemorrhage 
  • Vorinostat Combined with High-Dose Gemcitabine, Busulfan, and Melphalan with Autologous Stem Cell Transplantation in Patients with Refractory Lymphomas. 
  • Waste not, want not. 
  • What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants? 
  • When 7 transmembrane receptors are not G protein-coupled receptors. 
  • Which comes first: the antigen or the adjuvant? 
  • Whole Recombinant Saccharomyces cerevisiae Yeast Expressing Ras Mutations as Treatment for Patients With Solid Tumors Bearing Ras Mutations: Results From a Phase 1 Trial. 
  • William Kaelin, Peter Ratcliffe, and Gregg Semenza receive the 2016 Albert Lasker Basic Medical Research Award. 
  • Wnt signaling suppresses MAPK-driven proliferation of intestinal stem cells. 
  • Wnt-signaling in retinal development and disease. 
  • [18F]-fluorodeoxyglucose positron emission tomography combined with computed tomography detection of asymptomatic late pulmonary toxicity in patients with non-Hodgkin lymphoma treated with rituximab-containing chemotherapy. 
  • beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. 
  • c-FLIP protects T lymphocytes from apoptosis in the intrinsic pathway. 
  • c-FLIP protects mature T lymphocytes from TCR-mediated killing. 
  • cDNA sequencing confirms HTLV-I expression in adult T-cell leukemia/lymphoma and different sequence variations in vivo and in vitro. 
  • gammadelta T cells: a new frontier for immunotherapy? 
  • hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia. 
  • iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions. 
  • mTOR deficiency reveals an immunological trade-off in innate resistance to mycobacterial infection in vivo 
  • mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation. 
  • miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways. 
  • microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease. 
  • microRNAs at the regulatory frontier: an investigation into how microRNAs impact the development and effector functions of CD4 T cells. 
  • mir-17-92: a polycistronic oncomir with pleiotropic functions. 
  • p47 GTPases: regulators of immunity to intracellular pathogens. 
  • p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells. 
  • polyethylene glycol-conjugated adenosine deaminase (ADA) therapy provides temporary immune reconstitution to a child with delayed-onset ADA deficiency. 
  • von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene. 
  • β-Catenin-regulated myeloid cell adhesion and migration determine wound healing. 
  • β2-Adrenergic receptor and adenylate cyclase gene polymorphisms affect sickle red cell adhesion 
  • γδ T cells: A new frontier for immunotherapy? 
• 

  Keywords of People

  • Liu, Boyi, Adjunct Assistant Professor in the Department of Anesthesiology, Anesthesiology
  • Saxena, Tarun, Project Manager, Dtmi, Duke Clinical & Translational Science Institute
  • Yi, John S, Assistant Professor of Surgery, Surgery, Surgical Sciences