Scopolamine

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  Subject Areas on Research

  • A pilot phase II randomized, cross-over, double-blinded, controlled efficacy study of octreotide versus hyoscine hydrobromide for control of noisy breathing at the end-of-life. 
  • A randomized, double-blind, multicenter trial comparing transdermal scopolamine plus ondansetron to ondansetron alone for the prevention of postoperative nausea and vomiting in the outpatient setting. 
  • Acute and chronic nicotine effects on working memory in aged rats. 
  • Acute nicotine interactions with nicotinic and muscarinic antagonists: working and reference memory effects in the 16-arm radial maze. 
  • Alteration of accessibility with scopolamine. 
  • Attention-modulating effects of cognitive enhancers. 
  • Attenuation of pharmacologically-induced attentional impairment by methylphenidate in rats. 
  • Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation. 
  • Characterization of the cognitive effects of combined muscarinic and nicotinic blockade. 
  • Cholinergic stimulation of phosphatidic acid formation by rat cornea in vitro. 
  • Cholinergic transmission in the dorsal hippocampus modulates trace but not delay fear conditioning. 
  • Cholinergic-dopaminergic interactions in radial-arm maze performance. 
  • Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia. 
  • Decreased hyperthermic effect of MK-801 in selectively bred hypercholinergic rats. 
  • Drug-induced reductions in ethanol intake in alcohol preferring and Fawn-Hooded rats. 
  • Effect of desiccating environmental stress versus systemic muscarinic AChR blockade on dry eye immunopathogenesis. 
  • Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically-induced impaired attention in rats. 
  • Effects of combined muscarinic and nicotinic blockade on choice accuracy in the radial-arm maze. 
  • Impairment of radial-arm maze performance in rats following lesions involving the cholinergic medial pathway: reversal by arecoline and differential effects of muscarinic and nicotinic antagonists. 
  • Interactive effects of D1 and D2 agonists with scopolamine on radial-arm maze performance. 
  • Intraoperative awareness and hypertensive crisis during high-dose fentanyl-diazepam-oxygen anesthesia. 
  • Muscarinic cholinergic regulation of epileptic spiking in kindling. 
  • Nicotinic and muscarinic interactions and choice accuracy in the radial-arm maze. 
  • Nicotinic, muscarinic and dopaminergic actions in the ventral hippocampus and the nucleus accumbens: effects on spatial working memory in rats. 
  • Nicotinic-dopaminergic relationships and radial-arm maze performance in rats. 
  • Palliative care pharmacotherapy literature summaries and analyses. 
  • Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion. 
  • Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats. 
  • Persistent neurobehavioral effects of early postnatal domoic acid exposure in rats. 
  • Persisting behavioral consequences of prenatal domoic acid exposure in rats. 
  • Potential interactions between GABAb and cholinergic systems: baclofen augments scopolamine-induced performance deficits in the eight-arm radial maze. 
  • Prenatal chlorpyrifos exposure in rats causes persistent behavioral alterations. 
  • Psychopharmacological investigations of a lead-induced long-term cognitive deficit in monkeys. 
  • Radial-arm maze performance in rats is impaired by a combination of nicotinic-cholinergic and D2 dopaminergic antagonist drugs. 
  • Reactivation treatment prevents the memory-impairing effects of scopolamine in preweanling rats. 
  • Reduction in ethanol preference following injection of centrally and peripherally acting antimuscarinic agents. 
  • Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning. 
  • Reversal of systemic toxic effects of scopolamine with physostigmine salicylate. 
  • Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague-Dawley rats. 
  • Scopolamine effects on Hamilton search task performance in monkeys. 
  • Scopolamine interactions with D1 and D2 antagonists on radial-arm maze performance in rats. 
  • Scopolamine sleep treatment in private practise. 
  • Sex-related spatial learning differences after prenatal cocaine exposure in the young adult rat. 
  • Synthesis, rodent biodistribution, dosimetry, metabolism, and monkey images of carbon-11-labeled (+)-2 alpha-tropanyl benzilate: a central muscarinic receptor imaging agent. 
  • The acute toxicity of drugs acting at cholinoceptive sites and twenty-four hour rhythms in brain acetylcholine. 
  • The ventral hippocampal muscarinic cholinergic system plays a key role in sexual dimorphisms of spatial working memory in rats. 
  • Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra. 
  • [Transdermal therapeutic system of scopolamine (TTS-S) in the prevention of sea sickness and its mechanism of action].