Cellular Senescence
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Subject Areas on Research
- Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression.
- Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation.
- Autophagic activity dictates the cellular response to oncogenic RAS.
- CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts.
- Cell cycle control and cancer.
- Cell senescence reduced the mechanotransduction sensitivity of porcine angular aqueous plexus cells to elevation of pressure.
- Disappearance of the telomere dysfunction-induced stress response in fully senescent cells.
- Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells.
- Effects of donor age on proteasome activity and senescence in trabecular meshwork cells.
- Epigenetic regulation of COL15A1 in smooth muscle cell replicative aging and atherosclerosis.
- Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway.
- Identification of a DNA Damage-Induced Alternative Splicing Pathway That Regulates p53 and Cellular Senescence Markers.
- Induction of sodium channel clustering by oligodendrocytes.
- LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers.
- Long-term male-specific chronic pain via telomere- and p53‑mediated spinal cord cellular senescence.
- Loss of MST/Hippo Signaling in a Genetically Engineered Mouse Model of Fusion-Positive Rhabdomyosarcoma Accelerates Tumorigenesis.
- Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease.
- Melanoma proliferation and chemoresistance controlled by the DEK oncogene.
- Metabolic stress is a barrier to Epstein-Barr virus-mediated B-cell immortalization.
- Negative regulation of the tumor suppressor p53 gene by microRNAs.
- Novel human bronchial epithelial cell lines for cystic fibrosis research.
- PRDX6 attenuates oxidative stress- and TGFbeta-induced abnormalities of human trabecular meshwork cells.
- Pan-cancer analysis of whole genomes.
- Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.
- Podocyte biology in segmental sclerosis and progressive glomerular injury.
- Premature T Cell Senescence in Pediatric CKD.
- Protocol to Generate Senescent Cells from the Mouse Hepatic Cell Line AML12 to Study Hepatic Aging.
- Religiosity, depression and telomere length in Chinese older adults.
- Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells.
- Selective coexpression of VEGF receptor 2 in EGFRvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature.
- T-cell Dysfunction in Glioblastoma: Applying a New Framework.
- Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus
- Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.
- The aged niche disrupts muscle stem cell quiescence.
- Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.
- Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway.
- Utility of telomerase-pot1 fusion protein in vascular tissue engineering.
- c-Jun promotes whereas JunB inhibits epidermal neoplasia.