Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.S., University of Tennessee Health Science Center 2003
  • Pediatric Retinal Fellowship, Ophthalmology, University of Tennessee Health Science Center 1996 - 1998
  • Retinal Fellowship, Ophthalmology, Scheie Eye Institute 1995 - 1996
  • Residency, Ophthalmology, Sapienza University of Rome (Italy) 1989 - 1993
  • M.D., Sapienza University of Rome (Italy) 1989
• 

  Duke Appointment History

  • Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 2017 - 2020
  • Instructor Temporary in the Department of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 2016 - 2017
• Research
• 

  Selected Grants

  • RST-001 awarded by Allergan, Inc. 2018 - 2033
  • An Open-label, Phase 1/2 Trial of Gene Therapy 4D-125 in Males with X-linked Retinitis Pigmentosa (XLRP) Caused by Mutations in the RPGR Gene awarded by 4D Molecular Therapeutics 2020 - 2025
  • A Prospective First-in-Human Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects with Autosomal Dominant Retinitis Pigmentosa (adRP) due to the P23H Mutation in the RHO Gene awarded by ProQR Therapeutics 2020 - 2025
  • CGNB3-001 awarded by Applied Genetic Technology Corporation 2019 - 2025
  • AGTC-501-RPGR-001 awarded by Applied Genetic Technology Corporation 2018 - 2024
  • Rate of Progression of EYS Related Retinal Degeneration awarded by Jaeb Center For Health Research 2020 - 2024
  • AGTC-RS1-001 awarded by Applied Genetic Technology Corporation 2017 - 2022
  • AGTC-XLRP-001 awarded by Applied Genetic Technology Corporation 2019 - 2022
  • Acucela 4429-301 awarded by Acucela Inc. 2019 - 2022
  • Safety and Efficacy of Zuretinol Acetate (ZA) Oral Solution in Subjects with Inherited Retinal Disease (IRD) Caused by Mutations in Retinal Pigment Epithelium Protein 65 (RPE65) or Lecithin: Retinol Acyltransferase (LRAT) awarded by Retinagenix Therapeutics 2020
  • Autoimmunity and Age-Related Macular Degeneration awarded by University of Tennessee Health Science Center 2016 - 2018
  • Retinitis Piementosa NHS P23H Mutation of the Rhodopsin Gene awarded by Ionis Pharmaceuticals Inc 2017
• 

  External Relationships

  • Acucela
  • Alia Therapeutics, Trento, Italy
  • Allergan/Retrosense
  • Applied Genetic Technologies Corporation
  • Astellas Institute for Regenerative Medicine, Marlborough, MA
  • Editas Medicine, Cambridge, MA
  • Endogena
  • Evolution Medical
  • Frontera Therapeutics
  • GLG Group, San Francisco, CA
  • Guidepoint Clinical
  • Gyroscope, Stevenage, UK (formerly Orbit Biomedical, Ambler, PA)
  • Huron Consulting Group, New York, NY
  • Kairos Ventures
  • Rhythm Pharmaceuticals, Boston, MA
  • Roivant Pharma, New York, NY
  • Teladoc Health (formerly Advance Medical, Inc., Westwood, MA)
• Publications & Artistic Works
• 

  Selected Publications

  • Books

    • Yu, M., D. Creel, and A. Iannaccone. Preface, 2019.
    • Yu, M., D. Creel, and A. Iannaccone. Handbook of clinical electrophysiology of vision, 2019. https://doi.org/10.1007/978-3-030-30417-1.
       Full Text

  • Academic Articles

    • Iannaccone, Alessandro, Emily Brabbit, Christiaan Lopez-Miro, Zoe Love, Victoria Griffiths, Marina Kedrov, and Neena B. Haider. “Interspecies Correlations between Human and Mouse NR2E3-Associated Recessive Disease.” J Clin Med 10, no. 3 (January 27, 2021). https://doi.org/10.3390/jcm10030475.
       Full Text  Link to Item
    • Duncan, Jacque L., Wendi Liang, Maureen G. Maguire, Isabelle Audo, Allison R. Ayala, David G. Birch, Joseph Carroll, et al. “Baseline Visual Field Findings in the RUSH2A Study: Associated Factors and Correlation With Other Measures of Disease Severity.” Am J Ophthalmol 219 (November 2020): 87–100. https://doi.org/10.1016/j.ajo.2020.05.024.
       Full Text  Link to Item
    • Birch, David G., Peiyao Cheng, Jacque L. Duncan, Allison R. Ayala, Maureen G. Maguire, Isabelle Audo, Janet K. Cheetham, et al. “The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline.” Transl Vis Sci Technol 9, no. 11 (October 2020): 9. https://doi.org/10.1167/tvst.9.11.9.
       Full Text  Link to Item
    • Ray, Thomas A., Kelly Cochran, Chris Kozlowski, Jingjing Wang, Graham Alexander, Martha A. Cady, William J. Spencer, et al. “Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease.” Nat Commun 11, no. 1 (July 3, 2020): 3328. https://doi.org/10.1038/s41467-020-17009-7.
       Full Text  Link to Item
    • Thompson, Debra A., Alessandro Iannaccone, Robin R. Ali, Vadim Y. Arshavsky, Isabelle Audo, James W. B. Bainbridge, Cagri G. Besirli, et al. “Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium.” Transl Vis Sci Technol 9, no. 7 (June 2020): 2. https://doi.org/10.1167/tvst.9.7.2.
       Full Text  Link to Item
    • Del Dotto, Valentina, Farid Ullah, Ivano Di Meo, Pamela Magini, Mirjana Gusic, Alessandra Maresca, Leonardo Caporali, et al. “SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder.” J Clin Invest 130, no. 1 (January 2, 2020): 108–25. https://doi.org/10.1172/JCI128514.
       Full Text  Link to Item
    • Yu, Jeannette J., Elvira Agrón, Traci E. Clemons, Amitha Domalpally, Freekje van Asten, Tiarnan D. Keenan, Catherine Cukras, Emily Y. Chew, and Emily Y. Age-Related Eye Disease Study 2 Research Group. “Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17.” Ophthalmology 126, no. 2 (February 2019): 261–73. https://doi.org/10.1016/j.ophtha.2018.08.017.
       Full Text  Link to Item
    • Mitchell, James, Fernanda Balem, Kalyan Tirupula, David Man, Harpreet Kaur Dhiman, Naveena Yanamala, Julian Ollesch, et al. “Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin.” Plos One 14, no. 5 (2019): e0214639. https://doi.org/10.1371/journal.pone.0214639.
       Full Text  Open Access Copy  Link to Item
    • Keenan, Tiarnan D., Elvira Agrón, Amitha Domalpally, Traci E. Clemons, Freekje van Asten, Wai T. Wong, Ronald G. Danis, et al. “Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.” Ophthalmology 125, no. 12 (December 2018): 1913–28. https://doi.org/10.1016/j.ophtha.2018.05.028.
       Full Text  Link to Item
    • Hollingsworth, T. J., Marko Z. Radic, Sarka Beranova-Giorgianni, Francesco Giorgianni, Yanming Wang, and Alessandro Iannaccone. “Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4).” Invest Ophthalmol Vis Sci 59, no. 10 (August 1, 2018): 3808–15. https://doi.org/10.1167/iovs.18-24118.
       Full Text  Open Access Copy  Link to Item
    • Duncan, Jacque L., Eric A. Pierce, Amy M. Laster, Stephen P. Daiger, David G. Birch, John D. Ash, Alessandro Iannaccone, et al. “Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps.” Transl Vis Sci Technol 7, no. 4 (July 2018): 6. https://doi.org/10.1167/tvst.7.4.6.
       Full Text  Open Access Copy  Link to Item
    • Myers, Mark H., Alessandro Iannaccone, and Gavin M. Bidelman. “A pilot investigation of audiovisual processing and multisensory integration in patients with inherited retinal dystrophies.” Bmc Ophthalmol 17, no. 1 (December 7, 2017): 240. https://doi.org/10.1186/s12886-017-0640-y.
       Full Text  Open Access Copy  Link to Item
    • Jiao, Xiaodong, Anren Li, Zi-Bing Jin, Xinjing Wang, Alessandro Iannaccone, Elias I. Traboulsi, Michael B. Gorin, Francesca Simonelli, and J Fielding Hejtmancik. “Identification and population history of CYP4V2 mutations in patients with Bietti crystalline corneoretinal dystrophy.” Eur J Hum Genet 25, no. 4 (April 2017): 461–71. https://doi.org/10.1038/ejhg.2016.184.
       Full Text  Link to Item
    • Hariri, Amir H., Hong Yang Zhang, Alexander Ho, Peter Francis, Richard G. Weleber, David G. Birch, Frederick L. Ferris, SriniVas R. Sadda, and SriniVas R. Trial of Oral Valproic Acid for Retinitis Pigmentosa Group. “Quantification of Ellipsoid Zone Changes in Retinitis Pigmentosa Using en Face Spectral Domain-Optical Coherence Tomography.” Jama Ophthalmol 134, no. 6 (June 1, 2016): 628–35. https://doi.org/10.1001/jamaophthalmol.2016.0502.
       Full Text  Link to Item
    • Wilkin, Justin, Natalie C. Kerr, Kathryn W. Byrd, Jewell C. Ward, and Alessandro Iannaccone. “Characterization of a Case of Pigmentary Retinopathy in Sanfilippo Syndrome Type IIIA Associated with Compound Heterozygous Mutations in the SGSH Gene.” Ophthalmic Genet 37, no. 2 (June 2016): 217–27. https://doi.org/10.3109/13816810.2015.1028647.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Giovannella Carboni, Gina Forma, Maria Giulia Mutolo, and Barbara J. Jennings. “Macular Pigment Optical Density and Measures of Macular Function: Test-Retest Variability, Cross-Sectional Correlations, and Findings from the Zeaxanthin Pilot Study of Response to Supplementation (ZEASTRESS-Pilot).” Foods 5, no. 2 (April 29, 2016). https://doi.org/10.3390/foods5020032.
       Full Text  Link to Item
    • Smith, Travis B., Maria Parker, Peter N. Steinkamp, Richard G. Weleber, Ning Smith, David J. Wilson, David J. VPA Clinical Trial Study Group, and David J. EZ Working Group. “Structure-Function Modeling of Optical Coherence Tomography and Standard Automated Perimetry in the Retina of Patients with Autosomal Dominant Retinitis Pigmentosa.” Plos One 11, no. 2 (2016): e0148022. https://doi.org/10.1371/journal.pone.0148022.
       Full Text  Link to Item
    • Yatsenko, S. A., H. A. Bakos, K. Vitullo, M. Kedrov, A. Kishore, B. J. Jennings, U. Surti, et al. “High-resolution microarray analysis unravels complex Xq28 aberrations in patients and carriers affected by X-linked blue cone monochromacy.” Clin Genet 89, no. 1 (January 2016): 82–87. https://doi.org/10.1111/cge.12638.
       Full Text  Open Access Copy  Link to Item
    • Hood, Michael Philip, Natalie Christine Kerr, Nizar Smaoui, and Alessandro Iannaccone. “Abnormal cone ERGs in a family with congenital nystagmus and photophobia harboring a p.X423Lfs mutation in the PAX6 gene.” Doc Ophthalmol 130, no. 2 (April 2015): 157–64. https://doi.org/10.1007/s10633-014-9477-3.
       Full Text  Link to Item
    • Thompson, Debra A., Robin R. Ali, Eyal Banin, Kari E. Branham, John G. Flannery, David M. Gamm, William W. Hauswirth, et al. “Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium.” Invest Ophthalmol Vis Sci 56, no. 2 (February 9, 2015): 918–31. https://doi.org/10.1167/iovs.14-16049.
       Full Text  Link to Item
    • Huntington Study Group Reach2HD Investigators, S. R. “Safety, tolerability, and efficacy of PBT2 in Huntington's disease: a phase 2, randomised, double-blind, placebo-controlled trial.” Lancet Neurol 14, no. 1 (January 2015): 39–47. https://doi.org/10.1016/S1474-4422(14)70262-5.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Francesco Giorgianni, David D. New, T. J. Hollingsworth, Allison Umfress, Albert H. Alhatem, Indira Neeli, et al. “Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis.” Plos One 10, no. 12 (2015): e0145323. https://doi.org/10.1371/journal.pone.0145323.
       Full Text  Open Access Copy  Link to Item
    • Luo, Xunda, Artur V. Cideciyan, Alessandro Iannaccone, Alejandro J. Roman, Lauren C. Ditta, Barbara J. Jennings, Svetlana A. Yatsenko, et al. “Blue cone monochromacy: visual function and efficacy outcome measures for clinical trials.” Plos One 10, no. 4 (2015): e0125700. https://doi.org/10.1371/journal.pone.0125700.
       Full Text  Link to Item
    • Iannaccone, Alessandro, and Marco A. Zarbin. “A new era in medical therapy for retinal degenerative disease?” Lancet 384, no. 9953 (October 25, 2014): 1482–84. https://doi.org/10.1016/S0140-6736(14)60956-9.
       Full Text  Link to Item
    • Iannaccone, Alessandro. “Measuring dark adaptation in the elderly: a predictor of who may develop macular degeneration?” Invest Ophthalmol Vis Sci 55, no. 8 (August 4, 2014): 4790. https://doi.org/10.1167/iovs.14-15135.
       Full Text  Link to Item
    • Jackson, Gregory R., Ingrid U. Scott, Ivana K. Kim, David A. Quillen, Alessandro Iannaccone, and John G. Edwards. “Author response: additional considerations in the utility of dark adaptometry for the diagnosis of age-related macular degeneration.” Invest Ophthalmol Vis Sci 55, no. 5 (May 19, 2014): 3149. https://doi.org/10.1167/iovs.14-14569.
       Full Text  Link to Item
    • Jackson, Gregory R., Ingrid U. Scott, Ivana K. Kim, David A. Quillen, Alessandro Iannaccone, and John G. Edwards. “Diagnostic sensitivity and specificity of dark adaptometry for detection of age-related macular degeneration.” Invest Ophthalmol Vis Sci 55, no. 3 (March 10, 2014): 1427–31. https://doi.org/10.1167/iovs.13-13745.
       Full Text  Link to Item
    • Vishwanathan, Rohini, Alessandro Iannaccone, Tammy M. Scott, Stephen B. Kritchevsky, Barbara J. Jennings, Giovannella Carboni, Gina Forma, et al. “Macular pigment optical density is related to cognitive function in older people.” Age Ageing 43, no. 2 (March 2014): 271–75. https://doi.org/10.1093/ageing/aft210.
       Full Text  Link to Item
    • Lucariello, Angela, Angelica Perna, Carmine Sellitto, Alfonso Baldi, Alessandro Iannaccone, Luigi Cobellis, Antonio De Luca, and Maria De Falco. “Modulation of wolframin expression in human placenta during pregnancy: comparison among physiological and pathological states.” Biomed Res Int 2014 (2014): 985478. https://doi.org/10.1155/2014/985478.
       Full Text  Link to Item
    • Wang, Xia, Hui Wang, Vincent Sun, Han-Fang Tuan, Vafa Keser, Keqing Wang, Huanan Ren, et al. “Comprehensive molecular diagnosis of 179 Leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing.” J Med Genet 50, no. 10 (October 2013): 674–88. https://doi.org/10.1136/jmedgenet-2013-101558.
       Full Text  Link to Item
    • Cox, Kyle F., Natalie C. Kerr, Marina Kedrov, Darryl Nishimura, Barbara J. Jennings, Edwin M. Stone, Val C. Sheffield, and Alessandro Iannaccone. “Phenotypic expression of Bardet-Biedl syndrome in patients homozygous for the common M390R mutation in the BBS1 gene.” Vision Res 75 (December 15, 2012): 77–87. https://doi.org/10.1016/j.visres.2012.08.005.
       Full Text  Link to Item
    • Branham, Kari, Mohammad Othman, Matthew Brumm, Athanasios J. Karoukis, Pelin Atmaca-Sonmez, Beverly M. Yashar, Sharon B. Schwartz, et al. “Mutations in RPGR and RP2 account for 15% of males with simplex retinal degenerative disease.” Invest Ophthalmol Vis Sci 53, no. 13 (December 13, 2012): 8232–37. https://doi.org/10.1167/iovs.12-11025.
       Full Text  Link to Item
    • Iannaccone, A. “Optical coherence tomography in rare pediatric cases.” Retina Today, no. SEPTEMBER 2012 (September 1, 2012): 66–69.
    • Carboni, Giovannella, Gina Forma, April D. Bond, Grazyna Adamus, and Alessandro Iannaccone. “Bilateral paraneoplastic optic neuropathy and unilateral retinal compromise in association with prostate cancer: a differential diagnostic challenge in a patient with unexplained visual loss.” Doc Ophthalmol 125, no. 1 (August 2012): 63–70. https://doi.org/10.1007/s10633-012-9327-0.
       Full Text  Link to Item
    • Burke, Tomas R., Gerald A. Fishman, Jana Zernant, Carl Schubert, Stephen H. Tsang, R Theodore Smith, Radha Ayyagari, et al. “Retinal phenotypes in patients homozygous for the G1961E mutation in the ABCA4 gene.” Invest Ophthalmol Vis Sci 53, no. 8 (July 3, 2012): 4458–67. https://doi.org/10.1167/iovs.11-9166.
       Full Text  Link to Item
    • De Falco, Maria, Lucrezia Manente, Angela Lucariello, Gianluca Baldi, Paola Fiore, Vincenza Laforgia, Alfonso Baldi, Alessandro Iannaccone, and Antonio De Luca. “Localization and distribution of wolframin in human tissues.” Front Biosci (Elite Ed) 4 (January 1, 2012): 1986–98. https://doi.org/10.2741/519.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Indira Neeli, Pratheebha Krishnamurthy, Nataliya I. Lenchik, Haibao Wan, Ivan C. Gerling, Dominic M. Desiderio, and Marko Z. Radic. “Autoimmune biomarkers in age-related macular degeneration: a possible role player in disease development and progression.” Adv Exp Med Biol 723 (2012): 11–16. https://doi.org/10.1007/978-1-4614-0631-0_2.
       Full Text  Link to Item
    • Jacobson, Samuel G., Artur V. Cideciyan, Ramakrishna Ratnakaram, Elise Heon, Sharon B. Schwartz, Alejandro J. Roman, Marc C. Peden, et al. “Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years.” Arch Ophthalmol 130, no. 1 (January 2012): 9–24. https://doi.org/10.1001/archophthalmol.2011.298.
       Full Text  Link to Item
    • Adamus, Grazyna, Lori Brown, Jade Schiffman, and Alessandro Iannaccone. “Diversity in autoimmunity against retinal, neuronal, and axonal antigens in acquired neuro-retinopathy.” J Ophthalmic Inflamm Infect 1, no. 3 (September 2011): 111–21. https://doi.org/10.1007/s12348-011-0028-8.
       Full Text  Link to Item
    • Sanders, Jason L., Alessandro Iannaccone, Robert M. Boudreau, Yvette P. Conley, Patricia L. Opresko, Wen-Chi Hsueh, Steven R. Cummings, et al. “The association of cataract with leukocyte telomere length in older adults: defining a new marker of aging.” J Gerontol a Biol Sci Med Sci 66, no. 6 (June 2011): 639–45. https://doi.org/10.1093/gerona/glr034.
       Full Text  Link to Item
    • Spencer, Kylee L., Lana M. Olson, Nathalie Schnetz-Boutaud, Paul Gallins, Anita Agarwal, Alessandro Iannaccone, Stephen B. Kritchevsky, et al. “Using genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degeneration.” Plos One 6, no. 3 (March 24, 2011): e17784. https://doi.org/10.1371/journal.pone.0017784.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Natalie C. Kerr, Tyson R. Kinnick, Jorge I. Calzada, and Edwin M. Stone. “Autosomal recessive best vitelliform macular dystrophy: report of a family and management of early-onset neovascular complications.” Arch Ophthalmol 129, no. 2 (February 2011): 211–17. https://doi.org/10.1001/archophthalmol.2010.367.
       Full Text  Link to Item
    • Sanders, J., A. Iannaccone, R. Boudreau, Y. Conley, W. Hsueh, R. M. Cawthon, T. Harris, and A. B. Newman. “THE ASSOCIATION OF LENS TRANSPARENCY AND CATARACT WITH TELOMERE LENGTH IN OLDER ADULTS.” Gerontologist 50 (October 1, 2010): 266–266.
       Link to Item
    • Philp, A. R., M. Jin, S. Li, E. I. Schindler, A. Iannaccone, B. L. Lam, R. G. Weleber, et al. “Predicting the pathogenicity of RPE65 mutations.” Hum Mutat 30, no. 8 (August 2009): 1183–88. https://doi.org/10.1002/humu.21033.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Kenneth H. Fung, Mari E. Eyestone, and Edwin M. Stone. “Treatment of adult-onset acute macular retinoschisis in enhanced s-cone syndrome with oral acetazolamide.” Am J Ophthalmol 147, no. 2 (February 2009): 307-312.e2. https://doi.org/10.1016/j.ajo.2008.08.003.
       Full Text  Link to Item
    • Miyake, Noriko, John Chilton, Maria Psatha, Long Cheng, Caroline Andrews, Wai-Man Chan, Krystal Law, et al. “Human CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndrome.” Science 321, no. 5890 (August 8, 2008): 839–43. https://doi.org/10.1126/science.1156121.
       Full Text  Link to Item
    • Renzi, Lisa Marie, Alessandro Iannaccone, Elizabeth Johnson, and Stephen Kritchevsky. “The relation between serum xanthophylls, fatty acids, macular pigment and cognitive function in the Health ABC Study.” Faseb Journal 22 (April 1, 2008).
       Link to Item
    • Iannaccone, Alessandro, Kevin T. Gallaher, Janda Buchholz, Barbara J. Jennings, Maureen Neitz, and D. J. Sidjanin. “Identification of two novel mutations in families with X-linked ocular albinism.” Mol Vis 13 (October 2, 2007): 1856–61.
       Link to Item
    • Iannaccone, Alessandro, Salvatore A. Tedesco, Kevin T. Gallaher, Hiroyuki Yamamoto, Steve Charles, and Thaddeus P. Dryja. “Fundus albipunctatus in a 6-year old girl due to compound heterozygous mutations in the RDH5 gene.” Doc Ophthalmol 115, no. 2 (September 2007): 111–16. https://doi.org/10.1007/s10633-007-9054-0.
       Full Text  Link to Item
    • Mura, Marco, Christina Sereda, Monica M. Jablonski, Ian M. MacDonald, and Alessandro Iannaccone. “Clinical and functional findings in choroideremia due to complete deletion of the CHM gene.” Arch Ophthalmol 125, no. 8 (August 2007): 1107–13. https://doi.org/10.1001/archopht.125.8.1107.
       Full Text  Link to Item
    • Gallaher, Kevin T., Marco Mura, Wm Andrew Todd, Tarsha L. Harris, Emily Kenyon, Tamara Harris, Karen C. Johnson, et al. “Estimation of macular pigment optical density in the elderly: test-retest variability and effect of optical blur in pseudophakic subjects.” Vision Res 47, no. 9 (April 2007): 1253–59. https://doi.org/10.1016/j.visres.2007.01.013.
       Full Text  Link to Item
    • Jablonski, Monica M., Alessandro Iannaccone, Drew H. Reynolds, Preston Gallaher, Shaun Allen, Xiaofei Wang, and Anton Reiner. “Age-related decline in VIP-positive parasympathetic nerve fibers in the human submacular choroid.” Invest Ophthalmol Vis Sci 48, no. 2 (February 2007): 479–85. https://doi.org/10.1167/iovs.06-0972.
       Full Text  Link to Item
    • Iannaccone, Alessandro, David Man, Naushin Waseem, Barbara J. Jennings, Madhavi Ganapathiraju, Kevin Gallaher, Elisheva Reese, Shomi S. Bhattacharya, and Judith Klein-Seetharaman. “Retinitis pigmentosa associated with rhodopsin mutations: Correlation between phenotypic variability and molecular effects.” Vision Res 46, no. 27 (December 2006): 4556–67. https://doi.org/10.1016/j.visres.2006.08.018.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Marco Mura, Frank M. Dyka, Maria Laura Ciccarelli, Beverly M. Yashar, Radha Ayyagari, Monica M. Jablonski, and Robert S. Molday. “An unusual X-linked retinoschisis phenotype and biochemical characterization of the W112C RS1 mutation.” Vision Res 46, no. 22 (October 2006): 3845–52. https://doi.org/10.1016/j.visres.2006.06.011.
       Full Text  Link to Item
    • Vasireddy, Vidyullatha, Monica M. Jablonski, Md Nawajes A. Mandal, Dorit Raz-Prag, Xiaofei F. Wang, Lesli Nizol, Alessandro Iannaccone, et al. “Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration.” Invest Ophthalmol Vis Sci 47, no. 10 (October 2006): 4558–68. https://doi.org/10.1167/iovs.06-0353.
       Full Text  Link to Item
    • Gruber, Michael, Richard Chappell, Amy Millen, Tara LaRowe, Suzen M. Moeller, Alessandro Iannaccone, Stephen B. Kritchevsky, and Julie Mares. “Correlates of serum lutein + zeaxanthin: findings from the Third National Health and Nutrition Examination Survey.” J Nutr 134, no. 9 (September 2004): 2387–94. https://doi.org/10.1093/jn/134.9.2387.
       Full Text  Link to Item
    • Wang, Xiaofei, Alessandro Iannaccone, and Monica M. Jablonski. “Contribution of Müller cells toward the regulation of photoreceptor outer segment assembly.” Neuron Glia Biol 1, no. 3 (August 2004): 291–96. https://doi.org/10.1017/S1740925X05000049.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Xiaofei Wang, Monica M. Jablonski, Sharon F. Kuo, Alfonso Baldi, Dominic Cosgrove, Cynthia C. Morton, and Anand Swaroop. “Increasing evidence for syndromic phenotypes associated with RPGR mutations.” Am J Ophthalmol 137, no. 4 (April 2004): 785–86. https://doi.org/10.1016/j.ajo.2003.11.050.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Stephen B. Kritchevsky, Maria Laura Ciccarelli, Salvatore A. Tedesco, Claudio Macaluso, William J. Kimberling, and Grant W. Somes. “Kinetics of visual field loss in Usher syndrome Type II.” Invest Ophthalmol Vis Sci 45, no. 3 (March 2004): 784–92. https://doi.org/10.1167/iovs.03-0906.
       Full Text  Link to Item
    • Wang, XiaoFei, Alessandro Iannaccone, and Monica M. Jablonski. “Permissive glycan support of photoreceptor outer segment assembly occurs via a non-metabolic mechanism.” Mol Vis 9 (December 16, 2003): 701–9.
       Link to Item
    • Mykytyn, Kirk, Darryl Y. Nishimura, Charles C. Searby, Gretel Beck, Kevin Bugge, Heidi L. Haines, Alberto S. Cornier, et al. “Evaluation of complex inheritance involving the most common Bardet-Biedl syndrome locus (BBS1).” Am J Hum Genet 72, no. 2 (February 2003): 429–37. https://doi.org/10.1086/346172.
       Full Text  Link to Item
    • Acar, Ceren, Alan J. Mears, Beverly M. Yashar, Anjali S. Maheshwary, Sten Andreasson, Alfonso Baldi, Paul A. Sieving, et al. “Mutation screening of patients with Leber Congenital Amaurosis or the enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene.” Mol Vis 9 (January 24, 2003): 14–17.
       Link to Item
    • Koenekoop, Robert K., Gerald A. Fishman, Alessandro Iannaccone, Hany Ezzeldin, Maria L. Ciccarelli, Alfonso Baldi, Janet S. Sunness, et al. “Electroretinographic abnormalities in parents of patients with Leber congenital amaurosis who have heterozygous GUCY2D mutations.” Arch Ophthalmol 120, no. 10 (October 2002): 1325–30. https://doi.org/10.1001/archopht.120.10.1325.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Nathalie McIntosh, Maria Laura Ciccarelli, Alfonso Baldi, P Allesandro Mutolo, Salvatore A. Tedesco, and Elizabeth C. Engle. “Familial unilateral Brown syndrome.” Ophthalmic Genet 23, no. 3 (September 2002): 175–84. https://doi.org/10.1076/opge.23.3.175.7882.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Richard A. McCluney, Vickie R. Brewer, Peter H. Spiegel, June S. Taylor, Natalie C. Kerr, and Enikö K. Pivnick. “Visual evoked potentials in children with neurofibromatosis type 1.” Doc Ophthalmol 105, no. 1 (July 2002): 63–81. https://doi.org/10.1023/a:1015719803719.
       Full Text  Link to Item
    • Breuer, Debra K., Beverly M. Yashar, Elena Filippova, Suja Hiriyanna, Robert H. Lyons, Alan J. Mears, Bersabell Asaye, et al. “A comprehensive mutation analysis of RP2 and RPGR in a North American cohort of families with X-linked retinitis pigmentosa.” Am J Hum Genet 70, no. 6 (June 2002): 1545–54. https://doi.org/10.1086/340848.
       Full Text  Link to Item
    • Lyubarsky, A. L., J. Lem, J. Chen, B. Falsini, A. Iannaccone, and E. N. Pugh. “Functionally rodless mice: transgenic models for the investigation of cone function in retinal disease and therapy.” Vision Res 42, no. 4 (February 2002): 401–15. https://doi.org/10.1016/s0042-6989(01)00214-0.
       Full Text  Link to Item
    • Wohabrebbi, Amira, Edward S. Umstot, Alessandro Iannaccone, Dominic M. Desiderio, and Monica M. Jablonski. “Downregulation of a unique photoreceptor protein correlates with improper outer segment assembly.” J Neurosci Res 67, no. 3 (February 1, 2002): 298–308. https://doi.org/10.1002/jnr.10106.
       Full Text  Link to Item
    • Cassina, Patricia, Hugo Peluffo, Mariana Pehar, Laura Martinez-Palma, Andrés Ressia, Joseph S. Beckman, Alvaro G. Estévez, and Luis Barbeito. “Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis.” J Neurosci Res 67, no. 1 (January 1, 2002): 21–29. https://doi.org/10.1002/jnr.10107.
       Full Text  Link to Item
    • Jablonski, M. M., J. Tombran-Tink, D. A. Mrazek, and A. Iannaccone. “Pigment epithelium-derived factor supports normal Müller cell development and glutamine synthetase expression after removal of the retinal pigment epithelium.” Glia 35, no. 1 (July 2001): 14–25. https://doi.org/10.1002/glia.1066.
       Full Text  Link to Item
    • Mykytyn, K., T. Braun, R. Carmi, N. B. Haider, C. C. Searby, M. Shastri, G. Beck, et al. “Identification of the gene that, when mutated, causes the human obesity syndrome BBS4.” Nat Genet 28, no. 2 (June 2001): 188–91. https://doi.org/10.1038/88925.
       Full Text  Link to Item
    • Iannaccone, A. “Genotype-phenotype correlations and differential diagnosis in autosomal dominant macular disease.” Doc Ophthalmol 102, no. 3 (May 2001): 197–236. https://doi.org/10.1023/a:1017566600871.
       Full Text  Link to Item
    • Jablonski, M. M., M. J. Graney, S. B. Kritchevsky, and A. Iannaccone. “Reliability assessment of a rod photoreceptor outer segment grading system.” Exp Eye Res 72, no. 5 (May 2001): 573–79. https://doi.org/10.1006/exer.2001.0987.
       Full Text  Link to Item
    • Nishimura, D. Y., C. C. Searby, R. Carmi, K. Elbedour, L. Van Maldergem, A. B. Fulton, B. L. Lam, et al. “Positional cloning of a novel gene on chromosome 16q causing Bardet-Biedl syndrome (BBS2).” Hum Mol Genet 10, no. 8 (April 1, 2001): 865–74. https://doi.org/10.1093/hmg/10.8.865.
       Full Text  Link to Item
    • Jablonski, M. M., M. J. Graney, S. B. Kritchevsky, and A. Iannaccone. “Reliability assessment of a rod photoreceptor outer segment grading system.” Investigative Ophthalmology & Visual Science 42, no. 4 (March 15, 2001): S364–S364.
       Link to Item
    • Jablonski, M. M., and A. Iannaccone. “Lactose supports Muller cell protein expression patterns in the absence of the retinal pigment epithelium.” Mol Vis 7 (February 13, 2001): 27–35.
       Link to Item
    • Jablonski, M. M., and A. Iannaccone. “Targeted disruption of Müller cell metabolism induces photoreceptor dysmorphogenesis.” Glia 32, no. 2 (November 2000): 192–204. https://doi.org/10.1002/1098-1136(200011)32:2<192::aid-glia80>3.0.co;2-6.
       Full Text  Link to Item
    • Jablonski, M. M., J. Tombran-Tink, D. A. Mrazek, and A. Iannaccone. “Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal.” J Neurosci 20, no. 19 (October 1, 2000): 7149–57.
       Link to Item
    • Jacobson, S. G., A. V. Cideciyan, A. Iannaccone, R. G. Weleber, G. A. Fishman, A. M. Maguire, L. M. Affatigato, et al. “Disease expression of RP1 mutations causing autosomal dominant retinitis pigmentosa.” Invest Ophthalmol Vis Sci 41, no. 7 (June 2000): 1898–1908.
       Link to Item
    • Iannaccone, A. E., J. DuPont, and J. E. Grunwald. “Human retinal hemodynamics following administration of 5-isosorbide mononitrate.” Curr Eye Res 20, no. 3 (March 2000): 205–10.
       Link to Item
    • Grunwald, J. E., A. Iannaccone, and J. DuPont. “Effect of isosorbide mononitrate on the human optic nerve and choroidal circulations.” Br J Ophthalmol 83, no. 2 (February 1999): 162–67. https://doi.org/10.1136/bjo.83.2.162.
       Full Text  Link to Item
    • Iannaccone, A. “Clinical and functional features of patients with dominant optic atrophy.” Arch Ophthalmol 117, no. 2 (February 1999): 287–88. https://doi.org/10.1001/archopht.117.2.287.
       Full Text  Link to Item
    • Hollo, G. “Plasma endothelin-1 concentrations in patients with retinal vein occlusions.” British Journal of Ophthalmology 83, no. 1 (January 1, 1999): 127–127.
       Link to Item
    • Hólló, G. “Plasma endothelial-1 concentrations in patients with retinal vein occlusions.” Br J Ophthalmol 83, no. 1 (January 1999): 127–28. https://doi.org/10.1136/bjo.83.1.126c.
       Full Text  Link to Item
    • Iannaccone, A., and C. Letizia. “Plasma endothelin-1 concentrations in patients with retinal vein occlusions - Reply.” British Journal of Ophthalmology 83, no. 1 (January 1, 1999): 127–28.
       Link to Item
    • Iannaccone, A., C. Letizia, S. Pazzaglia, E. M. Vingolo, G. Clemente, and M. R. Pannarale. “Plasma endothelin-1 concentrations in patients with retinal vein occlusions.” Br J Ophthalmol 82, no. 5 (May 1998): 498–503. https://doi.org/10.1136/bjo.82.5.498.
       Full Text  Link to Item
    • Iannaccone, A., J. E. Grunwald, and J. Dupont. “The effect of 5-isosorbide mononitrate (ISMO) on optic nerve head and foveal choroidal blood flow.” Investigative Ophthalmology and Visual Science 38, no. 4 (December 1, 1997).
    • Iannaccone, A., G. De Propris, S. Roncati, E. Rispoli, G. Del Porto, and M. R. Pannarale. “The ocular phenotype of the Bardet-Biedl syndrome. Comparison to non-syndromic retinitis pigmentosa.” Ophthalmic Genet 18, no. 1 (March 1997): 13–26. https://doi.org/10.3109/13816819709057879.
       Full Text  Link to Item
    • Letizia, C., A. Iannaccone, S. Cerci, G. Santi, M. Cilli, S. Coassin, M. R. Pannarale, and D. Scavo. “Erratum: Circulating endothelin-l in non-insulin-dependent diabetic patients with retinopathy (Hormone and Metabolic Research (1997) 29 (247-251)).” Hormone and Metabolic Research 29, no. 9 (January 1, 1997): 476.
    • Pannarale, M. R., B. Grammatico, A. Iannaccone, R. Forte, C. DeBernardo, L. Flagiello, E. M. Vingolo, and G. Del Porto. “Autosomal-dominant retinitis pigmentosa associated with an Arg-135-Trp point mutation of the rhodopsin gene. Clinical features and longitudinal observations.” Ophthalmology 103, no. 9 (September 1996): 1443–52. https://doi.org/10.1016/s0161-6420(96)30485-5.
       Full Text  Link to Item
    • Iannaccone, A., A. V. Cideciyan, V. C. Sheffield, E. M. Stone, and S. G. Jacobson. “Phenotype of chromosome 8q-linked autosomal dominant retinitis pigmentosa.” Investigative Ophthalmology and Visual Science 37, no. 3 (February 15, 1996).
    • Iannaccone, A., E. M. Vingolo, E. Rispoli, G. De Propris, P. Tanzilli, and M. R. Pannarale. “Electroretinographic alterations in the Laurence-Moon-Bardet-Biedl phenotype.” Acta Ophthalmol Scand 74, no. 1 (February 1996): 8–13. https://doi.org/10.1111/j.1600-0420.1996.tb00673.x.
       Full Text  Link to Item
    • Iannaccone, A., E. Rispoli, E. M. Vingolo, P. Onori, K. Steindl, D. Rispoli, and M. R. Pannarale. “Correlation between Goldmann perimetry and maximal electroretinogram response in retinitis pigmentosa.” Doc Ophthalmol 90, no. 2 (1995): 129–42. https://doi.org/10.1007/BF01203333.
       Full Text  Link to Item
    • Del Porto, G., E. M. Vingolo, K. Steindl, R. Forte, A. Iannaccone, E. Rispoli, and M. R. Pannarale. “Clinical heterogeneity of dominant optic atrophy: the contribution of visual function investigations to diagnosis.” Graefes Arch Clin Exp Ophthalmol 232, no. 12 (December 1994): 717–27. https://doi.org/10.1007/BF00184274.
       Full Text  Link to Item
    • Mutolo, P. A., M. L. Ciccarelli, and A. Iannaccone. “Schubert-Bornschein complete Congenital Stationary Night Blindness (SB-CSNB1) and tilted disc syndrome. A case report.” Annali Di Ottalmologia E Clinica Oculistica 120, no. 7 (October 12, 1994): 421–31.
    • Vingolo, E. M., K. Steindl, R. Forte, L. Zompatori, A. Iannaccone, A. Sciarra, G. Del Porto, and M. R. Pannarale. “Autosomal dominant simple microphthalmos.” J Med Genet 31, no. 9 (September 1994): 721–25. https://doi.org/10.1136/jmg.31.9.721.
       Full Text  Link to Item
    • Proto, F., A. De Leo, A. Iannaccone, C. Giusti, and E. M. Vingolo. “Kearns-Sayre Syndrome (KSS): Case report and review of the literature.” Annali Di Ottalmologia E Clinica Oculistica 120, no. 2 (January 1, 1994): 149–54.
    • Rispoli, E., A. Iannaccone, and E. M. Vingolo. “Low-noise electroretinogram recording techniques in retinitis pigmentosa.” Doc Ophthalmol 88, no. 1 (1994): 27–37. https://doi.org/10.1007/BF01203699.
       Full Text  Link to Item
    • Iannaccone, A., F. Scio, R. Tanzilli, L. Amoroso, and R. Lucarelli. “Central vein occlusion during hypoplatelet situation: Case report.” Annali Di Ottalmologia E Clinica Oculistica 119, no. 12 (December 1, 1993): 845–48.
    • Vingolo, E. M., E. Rispoli, D. Zicari, L. Pannarale, A. Iannaccone, and F. Fallucca. “Electrophysiologic monitoring of diabetic retinopathy in pregnancy.” Retina 13, no. 2 (1993): 99–106. https://doi.org/10.1097/00006982-199313020-00002.
       Full Text  Link to Item
    • Rispoli, E., E. M. Vingolo, and A. Iannaccone. “Thymopentin (Timunox®) in retinitis pigmentosa. Evaluation of its possible therapeutical effects after 18 months of treatment, preliminary results.” New Trends in Ophthalmology 6, no. 3 (January 1, 1991): 235–41.
    • Iannaccone, A., and M. Pannarale. “Autosomal dominant retinitis pigmentosa associated with an Arg-135-Trp point mutation of the rhodopsin gene.” Ophthalmology (Section 12 Embase), n.d.

  • Book Sections

    • Ali, M. H., A. Iannaccone, and L. Vajzovic. “Other inherited retinal diseases.” In Handbook of Pediatric Retinal OCT and the Eye-Brain Connection, 124–27, 2019. https://doi.org/10.1016/B978-0-323-60984-5.00027-5.
       Full Text
    • Ali, M. H., A. Iannaccone, and L. Vajzovic. “Retinitis pigmentosa.” In Handbook of Pediatric Retinal OCT and the Eye-Brain Connection, 105–9, 2019. https://doi.org/10.1016/B978-0-323-60984-5.00023-8.
       Full Text
    • Ali, M. H., A. Iannaccone, and L. Vajzovic. “Other forms of retinitis pigmentosa-usher syndrome, leber congenital amaurosis, and bardet-biedl syndrome.” In Handbook of Pediatric Retinal OCT and the Eye-Brain Connection, 110–14, 2019. https://doi.org/10.1016/B978-0-323-60984-5.00024-X.
       Full Text
    • Creel, D., M. Yu, and A. Iannaccone. “Characteristics of visual electrophysiology in albinism.” In Handbook of Clinical Electrophysiology of Vision, 203–13, 2019. https://doi.org/10.1007/978-3-030-30417-1_11.
       Full Text
    • Iannaccone, A., A. Senatore, W. J. Kheir, D. Creel, and M. Yu. “Characteristics of visual electrophysiology in inflammatory disorders.” In Handbook of Clinical Electrophysiology of Vision, 147–71, 2019. https://doi.org/10.1007/978-3-030-30417-1_8.
       Full Text
    • Kheir, W. J., M. Yu, A. Senatore, A. Racioppi, R. Gattegna, D. Creel, and A. Iannaccone. “Degenerative night-blinding disorders and cone and cone–rod dystrophies.” In Handbook of Clinical Electrophysiology of Vision, 77–109, 2019. https://doi.org/10.1007/978-3-030-30417-1_6.
       Full Text
    • Kheir, W. J., M. Yu, A. Senatore, R. Gattegna, A. Racioppi, D. Creel, and A. Iannaccone. “Macular dystrophies.” In Handbook of Clinical Electrophysiology of Vision, 51–75, 2019. https://doi.org/10.1007/978-3-030-30417-1_5.
       Full Text
    • Kheir, W. J., R. Gattegna, M. Yu, A. Racioppi, A. Senatore, D. Creel, and A. Iannaccone. “Congenital non-degenerative retinal diseases.” In Handbook of Clinical Electrophysiology of Vision, 37–50, 2019. https://doi.org/10.1007/978-3-030-30417-1_4.
       Full Text
    • Senatore, A., W. J. Kheir, M. Yu, A. Racioppi, R. Gattegna, D. Creel, and A. Iannaccone. “Syndromic disorders.” In Handbook of Clinical Electrophysiology of Vision, 111–45, 2019. https://doi.org/10.1007/978-3-030-30417-1_7.
       Full Text
    • Yu, M., A. Senatore, A. Iannaccone, W. J. Kheir, and D. Creel. “Characteristics of visual electrophysiology in retinal toxicities.” In Handbook of Clinical Electrophysiology of Vision, 173–90, 2019. https://doi.org/10.1007/978-3-030-30417-1_9.
       Full Text

  • Conference Papers

    • Gattegna, Roberto, Isaac Bleicher, and Alessandro Iannaccone. “Emerging Phenotypic Characteristics and Identification of Novel Mutations in Autosomal Recessive Retinitis Pigmentosa (ARRP) Associated with the EYS Gene.” In Investigative Ophthalmology & Visual Science, Vol. 60. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2019.
       Link to Item
    • Iannaccone, Alessandro, Faith Birnbaum, Rachel Champaigne, and Grazyna Adamus. “Basal Cell Carcinoma-Associated Retinopathy and Optic Neuropathy (BARN): A Novel Paraneoplastic Entity.” In Investigative Ophthalmology & Visual Science, Vol. 60. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2019.
       Link to Item
    • Iannaccone, Alessandro, and Marko Z. Radic. “Increased Protein Citrullination as a Trigger for Resident Immune System Activation, Intraretinal Inflammation, and Promotion of Anti-retinal Autoimmunity: Intersecting Paths in Retinal Degenerations of Potential Therapeutic Relevance.” In Adv Exp Med Biol, 1185:175–79, 2019. https://doi.org/10.1007/978-3-030-27378-1_29.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Jay Berdia, Wajiha Kheir, Lindsay Mighion, Nicholas Wang, Cristina DaSilva, Jie Duan, John J. Alexander, and John P-W Chiang. “Careful clinical-functional phenotyping combined with systematic, broad NGS Panel-based genotyping identify numerous novel disease-causing mutations and deletions in inherited retinal dystrophy (IRD) patients.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.
       Link to Item
    • Rafieetary, Salar, Joshua Barnett, Natalie Kerr, and Alessandro Iannaccone. “Retinal Changes and Nerve Fiber Layer Loss in Pediatric Patients on Vigabatrin: An Electroretinogram and Imaging Study.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.
       Link to Item
    • Skalak, Cindy, Wajiha Kheir, Jay Berdia, and Alessandro Iannaccone. “A simple, clinician-friendly perimetric approach to the differential diagnosis between blue cone monochromacy (BCM) and achromatopsia (ACHM): A pilot study.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.
       Link to Item
    • Hollingsworth, T. J., Marko Z. Radic, Francesco Giorgianni, Sarka Beranova-Giorgianni, Diwa Koirala, Yanming Wang, and Alessandro Iannaccone. “Peptidylarginine deiminase 4 (PAD4) is the primary mediator of retinal citrullination in mice.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.
       Link to Item
    • Iannaccone, Alessandro, T. J. Hollingsworth, Natalia Lenchik, Sarka Beranova-Giorgianni, Ivan Gerling, Marko Z. Radic, and Francesco Giorgianni. “Association between macular phenotype and serum auto-antibodies (AAbs) against macular antigens in age-related macular degeneration (AMD): Preliminary studies.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.
       Link to Item
    • Koirala, Diwa, Alessandro Iannaccone, T. J. Hollingsworth, Sarka Beranova-Giorgianni, Ivan Gerling, Marko Z. Radic, and Francesco Giorgianni. “The superoxide dismutase 1 knock out (SOD1 KO) mouse develops age-dependent auto reactivity to ocular antigens.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.
       Link to Item
    • Epstein, Rebecca, David New, T. J. Hollingsworth, Isabelle Meunier, Nataliya Lenchik, Qingxian Lu, Ivan Gerling, Christian P. Hamel, Marko Radic, and Alessandro Iannaccone. “Defective mer-tyrosine kinase (mer-TK) function is associated with anti-arrestin and anti-interphotoreceptor retinoid-binding protein (IRBP) autoantibodies (AAbs) in Mer, Axl, Tyro3 -/-(TAM) mice and in autosomal recessive retinitis pigmentosa (arRP) patients with a null MERTK mutation.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.
       Link to Item
    • Hollingsworth, T. J., David New, Francesco Giorgianni, Nataliya Lenchik, Sarka Beranova-Giorgianni, Ivan Gerling, Qingxian Lu, Yanming Wang, Marko Radic, and Alessandro Iannaccone. “Peptidylarginine deiminase (PAD4) expression and citrullination levels in normal human and mouse retinas and in murine models of late- (Sod1(-/-)) and early-onset (Tyro3(-/-), Axl(-/-), Mertk -/- or TAM mice) retinal degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.
       Link to Item
    • Iannaccone, Alessandro, David New, Francesco Giorgianni, Nataliya Lenchik, Sarka Beranova-Giorgianni, Ivan Gerling, and Marko Radic. “Sera from subjects with age-related macular degeneration (AMD) exhibit strong autoreactivity against human macular Heat Shock Proteins (HSPs).” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.
       Link to Item
    • Alhatem, Albert H., Nataliya Lenchik, Sarka Beranova-Giorgianni, Mikael Klingeborn, David D. New, Francesco Giorgianni, Ivan Gerling, Marko Radic, Catherine Bowes Rickman, and Alessandro Iannaccone. “The Apolipoprotein E4 Targeted Replacement (APOE4 TR) Mouse Model of Age-Related Macular Degeneration (AMD) Exhibits Anti-Retinal Autoreactivity.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.
       Link to Item
    • Epstein, Rebecca Satterfield, Eric Sollenberger, Grazyna Adamus, and Alessandro Iannaccone. “Clinical, functional, and imaging findings in cancer cancer-associated retinopathy (CAR) and optic neuropathy (CAON).” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.
       Link to Item
    • Iannaccone, Alessandro, Albert H. Alhatem, Nataliya Lenchik, Francesco Giorgianni, David D. New, Sarka Beranova-Giorgianni, Ivan Gerling, Rafael Ufret-Vincenty, and Marko Radic. “Evidence for Anti- Retinal Auto-Antibodies (AAbs) in the Complement Factor H Chimeric Transgenic (CfhTg) Mouse Model of Age-Related Macular Degeneration (AMD).” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.
       Link to Item
    • Sollenberger, Eric, Rebecca S. Epstein, Grazyna Adamus, and Alessandro Iannaccone. “Clinical characteristics of autoimmune neuro-retinopathy (AINR).” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.
       Link to Item
    • Lenchik, Nataliya, Francesco Giorgianni, Sarka Beranova-Giorgianni, Ivan Gerling, Marko Radic, and Alessandro Iannaccone. “Identification of Human Macular Tissue Antigens Recognized by Serum Auto-Antibodies (auto-Abs) in Patients with Age-Related Macular Degeneration (AMD).” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.
       Link to Item
    • Brumm, M. V., K. Branham, M. Othman, A. J. Karoukis, R. G. Weleber, A. Iannaccone, S. G. Jacobson, A. Swaroop, and J. R. Heckenlively. “X-Linked Recessive Mutations in Simplex Males With Retinitis Pigmentosa.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.
       Link to Item
    • Carboni, G., G. Forma, M. G. Mutolo, B. J. Jennings, and A. Iannaccone. “Cross-Sectional Correlations Between Macular Pigment Optical Density (MPOD) and Measures of Macular Function.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.
       Link to Item
    • Forma, G., G. Carboni, M. G. Mutolo, B. J. Jennings, and A. Iannaccone. “Test-Retest Variability of Measures of Macular Function: Baseline Findings From the Zeaxanthin Pilot Study of Response to Supplementation (ZEASTRESS-Pilot).” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.
       Link to Item
    • Iannaccone, A., I. Neeli, N. Lenchik, P. Krishnamurthy, I. C. Gerling, and M. Z. Radic. “Serological Patterns of Autoreactivity and Identification of Novel Auto-Antigens in Age-Related Macular Degeneration (AMD).” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.
       Link to Item
    • Radhakrishnan, S. S., G. Forma, G. Carboni, M. G. Mutolo, G. Adamus, and A. Iannaccone. “Patterns of Visual Function Loss in Autoimmune Neuro-Retinopathy (AINR): Psychophysical and Electrophysiological Findings.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.
       Link to Item
    • Iannaccone, Alessandro, Mohammad I. Othman, April D. Cantrell, Barbara J. Jennings, Kari Branham, and Anand Swaroop. “Retinal phenotype of an X-linked pseudo-Usher syndrome in association with the G173R mutation in the RPGR gene.” In Adv Exp Med Biol, 613:221–27, 2008. https://doi.org/10.1007/978-0-387-74904-4_25.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Marco Mura, Kevin T. Gallaher, Elizabeth J. Johnson, William Andrew Todd, Emily Kenyon, Tarsha L. Harris, et al. “Macular pigment optical density in the elderly: findings in a large biracial Midsouth population sample.” In Invest Ophthalmol Vis Sci, 48:1458–65, 2007. https://doi.org/10.1167/iovs.06-0438.
       Full Text  Link to Item
    • Iannaccone, Alessandro, Kirk Mykytyn, Antonio M. Persico, Charles C. Searby, Alfonso Baldi, Monica M. Jablonski, and Val C. Sheffield. “Clinical evidence of decreased olfaction in Bardet-Biedl syndrome caused by a deletion in the BBS4 gene.” In Am J Med Genet A, 132A:343–46, 2005. https://doi.org/10.1002/ajmg.a.30512.
       Full Text  Link to Item
    • Meng, S., S. Satterfield, A. Iannaccone, E. Kenyon, T. Harris, A. Newman, E. Simonsick, and S. Kritchevsky. “Self-reported and measured visual function and walking difficulty in community-dwelling older adults.” In American Journal of Epidemiology, 159:S2–S2. OXFORD UNIV PRESS INC, 2004.
       Link to Item
    • Iannaccone, A., D. K. Breuer, X. F. Wang, S. F. Kuo, E. M. Normando, E. Filippova, A. Baldi, et al. “Clinical and immunohistochemical evidence for an X linked retinitis pigmentosa syndrome with recurrent infections and hearing loss in association with an RPGR mutation.” In J Med Genet, 40:e118, 2003. https://doi.org/10.1136/jmg.40.11.e118.
       Full Text  Link to Item
    • Jablonski, M. M., X. F. Wang, L. Lu, M. Pardue, A. Iannaccone, D. Goldowitz, and R. W. Williams. “Regional mutagenesis of the mouse genome: An update of ocular phenotypes.” In Investigative Ophthalmology & Visual Science, 44:U673–U673. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2003.
       Link to Item
    • Lotery, A. J., S. G. Jacobson, R. G. Weleber, A. Iannaccone, P. Namperumalsamy, G. A. Fishman, A. Levin, B. L. Lam, E. Heon, and E. M. Stone. “Prevalence of mutations in the RPE65, CRX, AIPL1, TULP1, GUCY2D and CRB1 genes in Leber Congenital Amaurosis.” In Investigative Ophthalmology & Visual Science, 44:U397–U397. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2003.
       Link to Item
    • Iannaccone, Alessandro. “Usher syndrome: correlation between visual field size and maximal ERG response b-wave amplitude.” In Adv Exp Med Biol, 533:123–31, 2003. https://doi.org/10.1007/978-1-4615-0067-4_16.
       Full Text  Link to Item
    • Iannaccone, A., B. M. Yashar, M. L. Ciccarelli, E. L. Bingham, V. Gasparri, A. Baldi, M. M. Jablonski, R. Ayyaggari, and P. A. Sieving. “Phenotype of X-linked juvenile retinoschisis (XLRS) associated with RS1 missense mutations.” In Investigative Ophthalmology & Visual Science, 43:U272–U272. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2002.
       Link to Item
    • Wohabrebbi, A., E. S. Umstot, A. Iannaccone, D. M. Desiderio, and M. M. Jablonski. “Characterization of the XAP-1 antigen using differential centrifugation. second-dimensional gel electrophoresis, and MALDI-TOF MS.” In Investigative Ophthalmology & Visual Science, 43:U314–U314. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2002.
       Link to Item
    • Ezzeldin, H., J. L. King, P. Coan, T. Millender-Swain, A. Baldi, A. Iannaccone, S. G. Jacobson, and S. J. Pittler. “Promoter and mutational analysis of the photoreceptor guanylate cyclase I gene.” In Investigative Ophthalmology & Visual Science, 42:S353–S353. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2001.
       Link to Item
    • Iannaccone, A., M. L. Ciccarelli, D. J. Orten, M. D. Weston, A. Baldi, M. M. Jablonski, and W. J. Kimberling. “Kinetics of visual field loss in Usher syndrome type 2.” In Investigative Ophthalmology & Visual Science, 42:S77–S77. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2001.
       Link to Item
    • Wohabrebbi, A., A. Iannaccone, and M. M. Jablonski. “Downregulation of a novel photoreceptor protein correlates with improper outer segment assembly.” In Investigative Ophthalmology & Visual Science, 42:S192–S192. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2001.
       Link to Item
    • Iannaccone, A., P. K. Swain, A. Baldi, M. Conciatori, M. L. Ciccarelli, and A. Swaroop. “Autosomal dominant cone-rod dystrophy with cystoid macular edema.” In Investigative Ophthalmology & Visual Science, 41:S882–S882. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2000.
       Link to Item
    • Parker, T. A., and A. Iannaccone. “Correlation between Goldmann visual field size and maximal ERG response in patients with Usher syndrome.” In Investigative Ophthalmology & Visual Science, 41:S890–S890. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2000.
       Link to Item
    • Iannaccone, Alessandro, Benedetto Falsini, Neena Haider, Giuseppe Del Porto, Edwin M. Stone, and Val C. Sheffield. “Bardet-Biedl Syndrome,” 189–99. Springer US, 1999. https://doi.org/10.1007/978-0-585-33172-0_19.
       Full Text
    • IANNACCONE, A., E. M. VINGOLO, R. FORTE, M. RISPOLI, L. ARRICO, and E. RISPOLI. “CLINICAL AND ELECTRORETINOGRAPHIC FINDINGS IN THE GOLDMANN-FAVRE VITREORETINAL DYSTROPHY.” In Investigative Ophthalmology & Visual Science, 36:S926–S926. LIPPINCOTT-RAVEN PUBL, 1995.
       Link to Item
    • RISPOLI, E., A. IANNACCONE, E. M. VINGOLO, and M. RISPOLI. “ROD ERG FREQUENCY-RESPONSE FUNCTION - NORMATIVE DATA AND CLINICAL-APPLICATIONS.” In Investigative Ophthalmology & Visual Science, 36:S446–S446. LIPPINCOTT-RAVEN PUBL, 1995.
       Link to Item
    • VINGOLO, E. M., E. RISPOLI, B. S. GRAMMATICO, A. IANNACCONE, C. DEBERNARDO, and L. PANNARALE. “DIFFERENT ROD PATHWAYS ABNORMALITIES IN RP(2) AND RP(3) XL-RP CARRIERS.” In Investigative Ophthalmology & Visual Science, 36:S925–S925. LIPPINCOTT-RAVEN PUBL, 1995.
       Link to Item
    • Iannaccone, A., E. M. Vingolo, R. Forte, P. Tanzilli, B. Grammatico, C. DeBernardo, E. Rispoli, G. DelPorto, and M. R. Pannarale. “Scotopic threshold responses and rod intensity-response functions as sensitive indicators of the carrier status in X-linked recessive retinitis pigmentosa.” In Degenerative Diseases of the Retina, edited by R. E. Anderson, M. M. LaVail, and J. G. Hollyfield, 371–76. PLENUM PRESS DIV PLENUM PUBLISHING CORP, 1995.
       Link to Item
    • Vingolo, E. M., A. Bellelli, M. Santori, L. Pannarale, R. Forte, A. Iannaccone, and R. Grenga. “Cataractogenesis in retinitis pigmentosa - Spectroscopic fluorescence analysis of aqueous humor composition.” In Degenerative Diseases of the Retina, edited by R. E. Anderson, M. M. LaVail, and J. G. Hollyfield, 403–7. PLENUM PRESS DIV PLENUM PUBLISHING CORP, 1995.
       Link to Item
    • FORTE, R., L. PANNARALE, A. IANNACCONE, E. M. VINGOLO, G. SANTI, and M. R. PANNARALE. “CYSTOID MACULAR EDEMA IN RETINITIS-PIGMENTOSA - CLINICAL AND FUNCTIONAL-EVALUATION OF PATIENTS TREATED WITH DEFLAZACORT.” In Investigative Ophthalmology & Visual Science, 35:1958–1958. LIPPINCOTT-RAVEN PUBL, 1994.
       Link to Item
    • IANNACCONE, A., E. M. VINGOLO, P. TANZILLI, and E. RISPOLI. “THE SCOTOPIC THRESHOLD RESPONSE IN DIFFERENT FORMS OF CONGENITAL STATIONARY NIGHT BLINDNESS.” In Investigative Ophthalmology & Visual Science, 35:1377–1377. LIPPINCOTT-RAVEN PUBL, 1994.
       Link to Item
    • RISPOLI, E., E. M. VINGOLO, A. IANNACCONE, R. FORTE, B. GRAMMATICO, C. DEBERNARDO, K. STEINDL, and M. R. PANNARALE. “ELECTRORETINOGRAPHIC MEASURES IN CARRIERS OF X-LINKED RECESSIVE RETINITIS-PIGMENTOSA.” In Investigative Ophthalmology & Visual Science, 35:2159–2159. LIPPINCOTT-RAVEN PUBL, 1994.
       Link to Item
    • VINGOLO, E. M., A. IANNACCONE, G. DEPROPRIS, P. TANZILLI, E. RISPOLI, and M. R. PANNARALE. “ELECTRORETINOGRAPHIC ABNORMALITIES IN THE LAURENCE-MOON-BARDET-BIEDL PHENOTYPE.” In Investigative Ophthalmology & Visual Science, 35:1958–1958. LIPPINCOTT-RAVEN PUBL, 1994.
       Link to Item
    • DEPROPRIS, G., A. IANNACCONE, E. M. VINGOLO, S. AMODEO, A. LEONARDI, and M. R. PANNARALE. “OPHTHALMOLOGICAL FEATURES OF THE LAURENCE-MOON-BARDET-BIEDL PHENOTYPE.” In Investigative Ophthalmology & Visual Science, 34:1369–1369. LIPPINCOTT-RAVEN PUBL, 1993.
       Link to Item
    • IANNACCONE, A., E. RISPOLI, E. M. VINGOLO, P. ONORI, and M. R. PANNARALE. “PROGRESSIVE NIGHT BLINDNESS AND SUPERNORMAL ERG RESPONSES - A CASE-REPORT.” In Investigative Ophthalmology & Visual Science, 34:1271–1271. LIPPINCOTT-RAVEN PUBL, 1993.
       Link to Item
    • VINGOLO, E. M., E. RISPOLI, A. IANNACCONE, K. STEINDL, P. TANZILLI, and G. DELPORTO. “SCOTOPIC THRESHOLD RESPONSE ABNORMALITIES IN X-LINKED RP CARRIERS.” In Investigative Ophthalmology & Visual Science, 34:1271–1271. LIPPINCOTT-RAVEN PUBL, 1993.
       Link to Item
    • DELPORTO, G., E. M. VINGOLO, D. DAVID, K. STEINDL, H. WEDEMANN, R. FORTE, A. IANNACCONE, A. GAL, and M. R. PANNARALE. “CLINICAL-FEATURES OF AUTOSOMAL-DOMINANT RETINITIS-PIGMENTOSA ASSOCIATED WITH THE GLY-188-ARG MUTATION OF THE RHODOPSIN GENE.” In Retinal Degeneration, edited by J. G. Hollyfield, R. E. Anderson, and M. M. LaVail, 91–101. PLENUM PRESS DIV PLENUM PUBLISHING CORP, 1993.
       Link to Item

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.