Overview
Synthetic Virology & Gene Therapy
Current Appointments & Affiliations
Professor in Surgery
·
2019 - Present
Surgery, Surgical Sciences,
Surgery
Director of Gene Therapy
·
2018 - Present
Surgery, Surgical Sciences,
Surgery
Professor of Molecular Genetics and Microbiology
·
2019 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Professor of Biomedical Engineering
·
2019 - Present
Biomedical Engineering,
Pratt School of Engineering
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
Enhancer-directed gene delivery for digit regeneration based on conserved epidermal factors.
Journal Article Proc Natl Acad Sci U S A · April 28, 2026 Limb loss remains a significant clinical challenge, but regenerative medicine approaches such as gene therapy offer a promising strategy to trigger endogenous regeneration programs. Optimal vector configurations and molecular targets for appendicular skele ... Full text Link to item CiteIn vivo site-specific engineering to reprogram T cells.
Journal Article Nature · April 2026 Engineered T cells, reprogrammed to express chimeric antigen receptors (CAR) or T cell receptors (TCR), have transformed cancer treatment and are being explored as therapeutics for autoimmune and infectious diseases. Enhancing T cell function through genom ... Full text Link to item CiteRewriting Renal Fate: The Evolving Landscape of Adeno-Associated Virus-Mediated Kidney Gene Therapies.
Journal Article Kidney360 · February 1, 2026 Full text Link to item CiteRecent Grants
Ex Vivo Delivery of Viral-Mediated Gene Therapy for the Amelioration of Post-Transplant Rejection
ResearchCo Investigator · Awarded by National Institutes of Health · 2026 - 2031Epithelial actions of a ubiquitin editor restrict immune-regulated sodium transport in hypertension
ResearchInvestigator · Awarded by National Institutes of Health · 2026 - 2031Interdisciplinary Research Training Program in AIDS
Inst. Training Prgm or CMEAdvisor · Awarded by National Institutes of Health · 2010 - 2030View All Grants
Education
University of North Carolina, Chapel Hill ·
2004
Ph.D.