Scholars@Duke
Xuhui Bao

Xuhui Bao

Adjunct Professor in the Department of Pathology
Pathology
xuhui.bao@duke.edu
Duke Box 3712, Durham, NC 27710
Duke Box 3712, Durham, NC 27710

Scholarly Works - Conferences

Abstract LB280: Enhancing glioblastoma radiotherapy by COMT inhibition

Conference Cancer Research · April 5, 2024 AbstractThere is an urgent unmet medical need to discover novel therapeutics to enhance the efficacy of glioma radiotherapy. Here we assessed the roles of catechol - o - methyltransferase COMT, a key enzyme ... Full text Cite

Abstract NG12: From cholesterol regulation to tumor suppression: Pcsk9 as a novel target for cancer immunotherapy

Conference Cancer Research · July 1, 2021 AbstractBackground: Despite its great success, immunotherapy is still of limited efficacy in many cancer patients. Numerous efforts are underway to develop novel strategies to enhance immune checkpoint inhib ... Full text Cite

BIOL-10. DISTRIBUTION AND VULNERABILITY OF TRANSCRIPTIONAL OUTPUTS ACROSS THE GENOME IN MYC-AMPLIFIED MEDULLOBLASTOMA CELLS

Conference Neuro-Oncology · June 1, 2021 AbstractMyc plays a central role in tumorigenesis by orchestrating the expression of genes essential to numerous cellular processes. While it is well established that Myc functions by binding to its target g ... Full text Cite

Abstract B47: Efficacy of GLI antagonists in triple-negative inflammatory breast cancer 2D and 3D models

Conference Cancer Epidemiology, Biomarkers & Prevention · July 1, 2018 AbstractOur objective was to investigate the differential effects of specific GLI1 antagonists in triple-negative inflammatory breast cancer 2D and 3D cell culture systems. Inflammatory breast cancer (IBC) a ... Full text Cite

A combinatorial immunotherapy for malignant brain tumors: D2C7 immunotoxin and immune checkpoint inhibitors.

Conference Journal of Clinical Oncology · March 1, 2017 102 Background: Immunotoxins can induce direct and rapid cytotoxicity by targeting specific tumor antigens. D2C7 is a unique recombinant immunotoxin targeting EGFRwt/EGFRvIII, two frequently overexpressed proteins on gliomas, and ... Full text Cite

Anti-Podoplanin Immunotoxin Therapy For Lung Cancer Treatment

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2017 Link to item Cite