Current Appointments & Affiliations
Professor of Pathology
·
2020 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2021 - Present
Duke Cancer Institute,
Institutes and Centers
Core Faculty Member, Duke-Margolis Institute for Health Policy
·
2024 - Present
Duke-Margolis Institute for Health Policy,
University Initiatives & Academic Support Units
Recent Publications
Surveying local CAR T-cell manufacturing processes to facilitate standardization and expand accessibility.
Journal Article J Transl Med · May 6, 2025 BACKGROUND: Chimeric antigen receptor T-cell (CAR T-cell) therapies have shown significant promise in treating cancers and other diseases. However, the manufacturing processes for CAR T-cell therapies exhibit considerable variability, which can affect trea ... Full text Link to item CiteIL-7-mediated expansion of autologous lymphocytes increases CD8+ VLA-4 expression and accumulation in glioblastoma models.
Journal Article J Clin Invest · April 17, 2025 The efficacy of T cell-activating therapies against glioma is limited by an immunosuppressive tumor microenvironment and tumor-induced T cell sequestration. We investigated whether peripherally infused non-antigen specific autologous lymphocytes (ALT) coul ... Full text Link to item CiteTransfusions in Lung Transplantation: Reply.
Journal Article Anesthesiology · December 1, 2024 Full text Link to item CiteRecent Grants
ACT EGFR (BRiTE)
ResearchPrincipal Investigator · Awarded by Adaptin Bio, Inc. · 2025 - 2026Process Development Grant for Gamm-delta T-cells
ResearchPrincipal Investigator · Awarded by AABB Foundation · 2025 - 2026NIH HEAL initiative: A first-in-class, mechanism-guided, cell-based therapy for complex regional pain syndrome
ResearchCo Investigator · Awarded by Cleveland Clinic Lerner College of Medicine · 2022 - 2025View All Grants
Education, Training & Certifications
University of Michigan, Ann Arbor ·
1996
M.D.