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Bhargav Srinivas Adagarla

Bioinformatician, Senior
Duke Clinical Research Institute
300 W Morgan St, 225P, Durham, NC 27701
300 W Morgan St, 225P, Durham, NC 27701

Scholarly Works


Evaluation of electronic health record to HL7® FHIR® mappings in pediatric research studies.

Journal article Int J Med Inform · April 1, 2026 BACKGROUND: eSource technologies that exchange patient data from electronic health records (EHR) to clinical study electronic data capture (EDC) systems can reduce data quality errors and decrease data collection time. However, the availability of site-spe ... Full text Link to item Cite

Noninvasive Ventilation or CPAP in the Initial Treatment Phase of Small Infants With Respiratory Failure.

Journal article Respir Care · February 2025 Background: Respiratory failure in infants is a common reason for admission to the pediatric ICU (PICU). Although high-flow nasal cannula (HFNC) is the preferred first-line treatment at our institution, some infants require CPAP or noninvasive ventilation ... Full text Link to item Cite

Evaluating Factors Associated With Telehealth Appropriateness in Outpatient Rheumatoid Arthritis Encounters Using the Encounter Appropriateness Score for You (EASY).

Journal article J Rheumatol · August 1, 2024 OBJECTIVE: Telehealth has been proposed as a safe and effective alternative to in-person care for rheumatoid arthritis (RA). The purpose of this study was to evaluate factors associated with telehealth appropriateness in outpatient RA encounters. METHODS: ... Full text Open Access Link to item Cite

Encounter Appropriateness Score for You Model: Development and Pilot Implementation of a Predictive Model to Identify Visits Appropriate for Telehealth in Rheumatology.

Journal article Arthritis Care Res (Hoboken) · January 2024 OBJECTIVE: We aimed to develop a decision-making tool to predict telehealth appropriateness for future rheumatology visits and expand telehealth care access. METHODS: The model was developed using the Encounter Appropriateness Score for You (EASY) and elec ... Full text Link to item Cite

Noninvasive Ventilation or CPAP for Postextubation Support in Small Infants.

Journal article Respir Care · December 28, 2023 BACKGROUND: Infants with a high risk of extubation failure are often treated with noninvasive ventilation (NIV) or CPAP, but data on the role of these support modalities following extubation are sparse. This report describes our experience using NIV or CPA ... Full text Link to item Cite

Assessing clinical site readiness for electronic health record (EHR)-to-electronic data capture (EDC) automated data collection.

Journal article Contemp Clin Trials · May 2023 BACKGROUND: eSource software is used to automatically copy a patient's electronic health record data into a clinical study's electronic case report form. However, there is little evidence to assist sponsors in identifying the best sites for multi-center eS ... Full text Link to item Cite

Timing of Treatment Outcomes and Risk Factors for Failure of BPAP in Patients Hospitalized for COPD Exacerbation.

Journal article Respir Care · December 2022 BACKGROUND: Patients hospitalized for COPD exacerbation have an increased risk of mortality, particularly among those who fail bi-level positive airway pressure (BPAP) for hypercapnic respiratory failure subsequently requiring invasive mechanical ventilati ... Full text Link to item Cite

Telehealth Made EASY: Understanding Provider Perceptions of Telehealth Appropriateness in Outpatient Rheumatology Encounters.

Journal article ACR Open Rheumatol · October 2022 OBJECTIVE: The purpose of this study was to evaluate a novel scoring system, the Encounter Appropriateness Score for You (EASY), to assess provider perceptions of telehealth appropriateness in rheumatology encounters. METHODS: The EASY scoring system promp ... Full text Open Access Link to item Cite

Evaluating Site-Level Implementations of the HL7 FHIR Standard to Support eSource Data Exchange in Clinical Research.

Journal article Stud Health Technol Inform · May 27, 2021 Direct extraction and use of electronic health record (EHR) data is a long-term and multifaceted endeavor that includes design, development, implementation and evaluation of methods and tools for semi-automating tasks in the research data collection proces ... Full text Link to item Cite

Impact of the COVID-19 pandemic on patterns of outpatient cardiovascular care.

Journal article Am Heart J · January 2021 BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic brought about abrupt changes in the way health care is delivered, and the impact of transitioning outpatient clinic visits to telehealth visits on processes of care and outcomes is unclear. METHO ... Full text Link to item Cite

Unanticipated Respiratory Compromise and Unplanned Intubations on General Medical and Surgical Floors.

Journal article Respir Care · September 2020 BACKGROUND: Unanticipated respiratory compromise that lead to unplanned intubations is a known phenomenon in hospitalized patients. Most events occur in patients at high risk in well-monitored units; less is known about the incidence, risk factors, and tra ... Full text Link to item Cite

Simulating retrieval from a highly clustered network: Implications for spoken word recognition

Journal article Frontiers in Psychology · December 1, 2011 Network science describes how entities in complex systems interact, and argues that the structure of the network influences processing. Clustering coefficient, C - one measure of network structure - refers to the extent to which neighbors of a node are als ... Full text Cite