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Brittany Elliott

Research Associate, Senior
Medicine, Cardiology

Scholarly Works - Preprints


Genome-wide profiling of RNA 2'-O-methylation in neurons and identification of orphan snoRNA targets.

Preprint · January 19, 2026 We have compared genome-wide patterns of RNA 2'-O-methylation (Nm) between two isogenic pairs of neurons. Each pair includes one line harboring a small deletion of orphan box C/D snoRNAs (SNORD116s) from the paternal chr15q11-q13 region. One isogenic pair ... Full text Link to item Cite

snoCLASH Reveals Extensive snoRNA-mRNA Interaction Networks.

Preprint · December 11, 2025 Small nucleolar RNAs (snoRNAs) are classically defined as guides for ribosomal RNA (rRNA) modification, yet increasing evidence suggests that box C/D snoRNAs also interact with non-rRNA transcripts. Systematic discovery of such interactions has been hinder ... Full text Link to item Cite

Rpl13a snoRNAs Downregulate Smooth Muscle Cell COX4I2 and Promote Neointimal Hyperplasia.

Preprint · July 27, 2025 BACKGROUND: Reactive oxygen species (ROS) augment the activation of vascular smooth muscle cells (SMCs) and promote neointimal hyperplasia evoked by arterial injury or atherogenesis. We have previously shown that small nucleolar RNAs (snoRNAs) from the Rpl ... Full text Link to item Cite