ConferenceJournal of Clinical Oncology · June 2025
11106Background:
Patients with cancer take different types of medication (e.g., enteral, parenteral), with varying treatment ...
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ConferenceJournal of Patient Reported Outcomes · December 1, 2023
Background: The pediatric patient-reported outcomes version of the common terminology criteria for adverse event measure was developed and validated for use in pediatric cancer clinical trials to better capture the symptom experiences through direct self-r ...
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ConferenceBlood · November 2, 2023
IntroductionSickle Cell Disease (SCD) is a genetic disorder that causes recurrent vaso-occlusive pain events, functional impairment, and nutritional deficiencies due to increased metabol ...
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ConferenceBlood · November 2, 2023
IntroductionAs people with sickle cell disease (SCD) age, they experience accelerated functional decline. Since historically survival for SCD has been limited to middle age, geriatric sy ...
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ConferenceApplied Research in Quality of Life · August 1, 2023
Women with heart failure report worse health-related quality of life on average, than men. This may result from actual differences in care or differing interpretations of and responses to survey questions. We investigated potential gender-based differentia ...
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ConferenceCancer Research · February 15, 2022
AbstractBackground: Few studies have assessed relationships between job loss due to breast cancer and well-being. These relationships may vary by race, work type, and functional difficulties.Methods: In the ...
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ConferenceJournal of Clinical Oncology · December 20, 2021
349527 Background: Symptoms are common during cancer care but often go undetected. Digital systems that elicit patient-reported outcomes (PRO) surveys may detect symptoms early and prompt clinicians to intervene, thereby alleviat ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · June 1, 2020
AbstractBackground Racial differences in cancer-related symptom burden are well-documented, and partly linked to inequities in symptom monitoring. Electronic patient-reported outcomes (ePROs) are useful for ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · June 1, 2020
AbstractBackground Racial disparities in time-to-treatment exist among cancer patients, with patients of color being more likely to experience treatment delays. Such racial differences in treatment initiatio ...
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ConferenceInflammatory Bowel Diseases · January 23, 2020
AbstractBackgroundPatient Reported Outcome Measurement Information System (PROMIS) provides valid, self-reported measures of physical, ...
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ConferenceCancer · January 1, 2020
BACKGROUND: Clinicians are the standard source for adverse event (AE) reporting in oncology trials, despite the subjective nature of symptomatic AEs. The authors designed a pediatric patient-reported outcome (PRO) instrument for symptomatic AEs to support ...
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ConferenceJournal of Clinical Oncology · September 20, 2019
203 Background: Health-related quality of life (HRQoL) is an important outcome in cancer care and research, but such data from sub-Saharan Africa are scant. We translated and validated the Pediatric Patient-Reported Outcome Measu ...
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ConferenceJournal of Pain · April 1, 2019
Patient-reported measures of pain intensity (i.e., numerical rating scales, visual analogue scales, and verbal rating scales) have been found to be reliable and valid in clinical trials. However, interpretations of pain intensity measures may vary within- ...
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ConferenceJ Sex Med · December 2018
BACKGROUND: There are multiple treatment options for men with localized prostate cancer that provide similar curative efficacy but differ in their impact on sexual functioning. AIM: To evaluate the psychometric properties of the Patient-Reported Outcomes M ...
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ConferenceBlood · November 29, 2018
AbstractBackground: Online patient and caregiver self-reporting for symptom and toxicity monitoring during chemotherapy can inform proactive clinical management and ameliorate serious adverse events. In adul ...
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ConferenceInt J Radiat Oncol Biol Phys · June 1, 2017
PURPOSE: To assess the feasibility of measuring symptomatic adverse events (AEs) in a multicenter clinical trial using the National Cancer Institute's Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE). METH ...
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ConferenceJournal of Clinical Oncology · May 20, 2017
10038 Background: Limitations in functional status and reduced health status are common among older adults with cancer, yet occupational and physical therapy (OT/PT) remain underutilized (Pergolotti, et.al. JGO,2015). For this po ...
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ConferenceJournal of Clinical Oncology · March 10, 2017
170 Background: Endocrine therapy under-utilization puts women at increased risk for breast cancer recurrence. The objective of this study was to determine if health-related quality of life (HRQOL) was significantly associated wi ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · February 1, 2017
AbstractObjective: There are over 3 million women in the United States living with breast cancer or who have a history of breast cancer. As the number of women undergoing treatments and surviving breast canc ...
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ConferenceAm J Obstet Gynecol · October 2016
BACKGROUND: There are currently no assessments of the impact of surgical complications on health-related quality of life in gynecology and gynecologic oncology. This is despite complications being a central focus of surgical outcome measurement, and an inc ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · March 1, 2016
AbstractIntroduction: Experiences of medical discrimination may impact women's decisions regarding breast cancer treatment. However, measures of perceived discrimination generally are not specific to the med ...
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ConferenceQual Life Res · November 2013
PURPOSE: To empirically determine clinically meaningful cut-scores on the 0-10 response scale of the revised Piper Fatigue Scale (PFS-R) and its shorter version (PFS-12). Breast cancer survivors were classified (i.e., none, mild, moderate, or severe fatigu ...
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ConferenceBlood · November 16, 2012
AbstractAbstract 4152Background:Peak oxygen consumption (VO2peak, in mL/kg*min) is assessed by cardio ...
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ConferenceBlood · November 16, 2012
AbstractAbstract 4471Background:Patient-Reported Outcome (PRO) measures help clinicians and researche ...
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ConferenceJournal of Clinical Oncology · February 10, 2012
3 Background: Comparative effectiveness research is urgently needed in prostate cancer because of the rapid adoption of newer and costlier radiation treatments such as IMRT and PT despite limited demonstrated benefit compared to ...
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ConferenceJ Clin Oncol · November 10, 2007
To evaluate and improve the use of cancer trial end points that reflect the patient's own perspective, the National Cancer Institute organized an international conference, Patient-Reported Outcomes Assessment in Cancer Trials (PROACT), in 2006. The 13 prec ...
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ConferenceJ Clin Oncol · November 10, 2007
For almost 30 years, the National Cancer Institute (NCI) has sponsored health-related quality-of-life (HRQOL) measures in cancer research as a means of including the patient's experience. The scope of NCI's research in symptom management and HRQOL is descr ...
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ConferenceValue Health · 2007
This article focuses on the necessary psychometric properties of a patient-reported outcomes (PROs) measure. Topics include the importance of reliability and validity, psychometric approaches used to provide reliability and validity estimates, the kinds of ...
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ConferenceQual Life Res · 2007
Item banks and Computerized Adaptive Testing (CAT) have the potential to greatly improve the assessment of health outcomes. This review describes the unique features of item banks and CAT and discusses how to develop item banks. In CAT, a computer selects ...
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ConferenceQual Life Res · 2007
BACKGROUND: In June 2004, the National Cancer Institute and the Drug Information Association co-sponsored the conference, "Improving the Measurement of Health Outcomes through the Applications of Item Response Theory (IRT) Modeling: Exploration of Item Ban ...
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ConferenceQual Life Res · 2007
BACKGROUND: Health outcomes researchers are increasingly applying Item Response Theory (IRT) methods to questionnaire development, evaluation, and refinement efforts. OBJECTIVE: To provide a brief overview of IRT, to review some of the critical issues asso ...
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ConferenceQual Life Res · 2007
This paper reviews important methodological considerations for developing item banks and computerized adaptive scales (commonly called computerized adaptive tests in the educational measurement literature, yielding the acronym CAT), including issues of the ...
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ConferenceQual Life Res · 2007
Many of the Institutes, Agencies and Centers that make up the US Department of Health and Human Services (DHHS) have recognized the need for better instrumentation in health outcomes research, and provide support, both internally and externally, for resear ...
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ConferenceBlood · November 16, 2006
AbstractBackground The lack of standardized response criteria is a major obstacle to the development of therapeutic agents for cGvHD. Consensus criteria for evaluating response in cGvHD have been recently pu ...
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