ConferenceCancer Immunology Research · February 18, 2026
AbstractMicrosatellite stable (MSS) stage IV colorectal cancer (CRC) is treated with chemotherapy (CT) and targeted therapy, but resistance is common, with only a 13% 5-year overall survival, and more eff ...
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ConferenceJournal of Clinical Oncology · February 2025
772Background:
The therapeutic resistance of pancreatic ductal adenocarcinoma (PDAC) to conventional cytotoxic therapy unders ...
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ConferenceAnn Surg Oncol · November 2022
BACKGROUND: Intraductal papillary mucinous neoplasms (IPMN) are the only radiographically identifiable precursor to pancreatic adenocarcinoma, yet little is known about how these lesions progress to cancer. Inflammation has been associated with dysplastic ...
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ConferenceCancer Research · July 1, 2017
AbstractImmune checkpoint inhibitors (ICIs) have made a profound impact on the treatment of a variety of cancers. However, as with any systemic treatment, toxicities are inevitable. With most classes of canc ...
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ConferenceCancer Research · February 1, 2017
AbstractInflammation regulates many aspects of gut homeostasis but is also a key component of colon cancer progression. While TGFβ signaling is known to regulate inflammatory responses within immune cells, w ...
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ConferenceMolecular Cancer Research · December 1, 2014
AbstractMounting evidence indicates that oncogenic Ras can modulate cell autonomous inflammatory cytokine production, although the underlying mechanism remains unclear. Here we show that squamous cell carcin ...
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ConferenceAm J Surg Pathol · April 2014
BACKGROUND: In the pancreas, poorly differentiated neuroendocrine carcinomas include small cell carcinoma and large cell neuroendocrine carcinoma and are rare; data regarding their pathologic and clinical features are very limited. DESIGN: A total of 107 p ...
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