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Christina Kelsey Zigler

Associate Professor in Population Health Sciences
Population Health Sciences
DUMC Box 104023, Durham, NC 27708
215 Morris Street, Suite 210, Durham, NC 27708


Dr. Zigler is an independent investigator dedicated to improving the ways we measure patient-centered, meaningful health states, specializing in pediatrics, rare diseases, and clinical trials. She also is a methodological co-investigator who supports the application of novel statistical approaches and measurement strategies across a diverse array of studies.

Her methodological expertise includes established qualitative and quantitative techniques (i.e. concept elicitation, cognitive testing, classical test theory, item-response theory) alongside innovative methods (i.e. novel ways to identify meaningful change), to ensure the measures are ultimately centered in the patients’ meaningful experiences. Further, she works in a variety of populations and contexts, including pediatrics, where patient-reported outcome measures empower children to report directly on their own health status, and rare diseases, where a creative and pragmatic approach to measure development is necessary and patient-centeredness is essential.

Areas of Expertise: Health Measurement, Health Behavior, and Health Services Research

Current Appointments & Affiliations

Associate Professor in Population Health Sciences · 2023 - Present Population Health Sciences, Basic Science Departments

Education, Training & Certifications

University of Pittsburgh · 2017 Ph.D.
University of Miami · 2010 M.S.Ed.