Current Appointments & Affiliations
Clinical Faculty in the Department of Surgery
·
2025 - Present
Surgery, Vascular and Endovascular Surgery,
Surgery
Recent Publications
The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cells.
Journal Article Biochim Biophys Acta · June 2013 A1/Bfl-1 is a NF-κB dependent, anti-apoptotic Bcl-2 family member that contains four Bcl-2 homology domains (BH) and an amphipathic C-terminal domain, and is expressed in endothelial cells (EC). Based on NF-κB reporter assays in bovine aortic EC, we have p ... Full text Link to item CiteA20 modulates lipid metabolism and energy production to promote liver regeneration.
Journal Article PloS one · March 2011 BackgroundLiver regeneration is clinically of major importance in the setting of liver injury, resection or transplantation. We have demonstrated that the NF-κB inhibitory protein A20 significantly improves recovery of liver function and mass foll ... Full text CiteA20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression.
Journal Article Liver Transpl · November 2009 The nuclear factor-kappaB inhibitory protein A20 demonstrates hepatoprotective abilities through combined antiapoptotic, anti-inflammatory, and pro-proliferative functions. Accordingly, overexpression of A20 in the liver protects mice from toxic hepatitis ... Full text Link to item CiteEducation, Training & Certifications
Tufts University, School of Medicine ·
1992
M.D.