Corinna Probst

Journal article mBio · June 9, 2026 UNLABELLED: The ability to sense, import, and detoxify copper (Cu) has been shown to be crucial for microbial pathogens to survive within an infected host. Previous studies conducted with the opportunistic human fungal pathogen Cryptococcus neoformans (Cn) ... Full text Link to item Cite

A broad-spectrum inhibitor of copper-exporting P<sub>1B</sub>-type ATPases.

Journal article Proceedings of the National Academy of Sciences of the United States of America · May 2026 Copper (Cu) transporting ATPases represent a highly conserved subclass of P-type ATPases with critical roles in Cu export and metalloenzyme synthesis. Despite their important biological roles and association with a wide range of human diseases, no high-aff ... Full text Cite

Rsp5-mediated ubiquitination of a functional analog of the Rim8 arrestin facilitates Rim pathway activation in Cryptococcus neoformans.

Journal article mBio · August 13, 2025 Pathogenic microorganisms use varied cellular processes to adapt to the particular stresses encountered in the infected host. These stresses include rapid alterations in ambient temperature, nutrient availability, and extracellular pH. Fungal pathogens, th ... Full text Link to item Cite

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Corinna Probst

Current Duke Appointments & Affiliations

Recent Scholarly Works

A cysteine-rich domain of the Cryptococcus neoformans Cuf1 transcription factor is required for high copper stress sensing and fungal virulence.

A broad-spectrum inhibitor of copper-exporting P<sub>1B</sub>-type ATPases.

Rsp5-mediated ubiquitination of a functional analog of the Rim8 arrestin facilitates Rim pathway activation in Cryptococcus neoformans.

Recent Grants

Copper homeostasis in fungal pathogenesis (R01)

Alspaugh Novo Nordisk

Metal Homeostasis in Yeast (R01)