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Dequing Wu

Research Scientist, Senior
Center for Population Health & Aging
Box 90088, Durham, NC 27708-0088
A104 Erwin Mill Building, 2024 W. Main St., Durham, NC 27705

Current Appointments & Affiliations


Recent Publications


Basic Science and Pathogenesis.

Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 2025 BackgroundAPOE4 is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), with a higher effect in females than in males. Identifying factors that may reduce the detrimental impact of APOE4 on AD is an important research objecti ... Full text Cite

Developing Topics.

Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 2025 BackgroundAccumulating evidence points to a major role of compromised immunity in Alzheimer's Disease (AD). The MIR146a and COMT genes are both known for their involvement in immune responses, as well as in AD-related traits. COMT also regulates t ... Full text Cite
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Recent Grants


The Long Life Family Study

ResearchSenior Investigator · Awarded by Washington University in St. Louis · 2019 - 2030

Understanding Alzheimer's Disease in the Context of the Aging

ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2025

View All Grants