Current Appointments & Affiliations
Research Scientist, Senior
Center for Population Health & Aging,
Duke Population Research Institute
Recent Publications
Basic Science and Pathogenesis.
Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 2025 BackgroundAPOE4 is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), with a higher effect in females than in males. Identifying factors that may reduce the detrimental impact of APOE4 on AD is an important research objecti ... Full text CiteDeveloping Topics.
Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 2025 BackgroundAccumulating evidence points to a major role of compromised immunity in Alzheimer's Disease (AD). The MIR146a and COMT genes are both known for their involvement in immune responses, as well as in AD-related traits. COMT also regulates t ... Full text CiteDeveloping Topics.
Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 2025 BackgroundInfections and neuroinflammation are increasingly recognized as key contributors to the pathogenesis of Alzheimer's disease (AD). Emerging evidence suggests that the immune-regulating genes GDF15 and MIR146A are promising targets for dev ... Full text CiteRecent Grants
Leveraging population-based human data to uncover mechanisms connecting Alzheimer's disease and common infections and facilitate vaccines repurposing for AD prevention
ResearchStatistician · Awarded by National Institutes of Health · 2021 - 2026Project 1: The Long Life Family Study
ResearchSenior Research Scientist · Awarded by Washington University in St. Louis · 2019 - 2025Understanding Alzheimer's Disease in the Context of the Aging
ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2025View All Grants