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Derek Cyr

Biostatistician, Principal
Duke Clinical Research Institute
300 West Morgan Street, Durham, NC 27701
300 West Morgan Street, Durham, NC 27701

Current Appointments & Affiliations


Recent Publications


Heart Failure With Preserved Ejection Fraction Across the Spectrum of Body Mass Index: Hemodynamic and Echocardiographic Characteristics and Outcomes.

Journal Article JACC Heart Fail · March 2026 BACKGROUND: Limited data are available on the relationship between body mass index (BMI) and heart failure (HF) physiology or clinical outcomes in patients with heart failure with preserved ejection fraction (HFpEF). OBJECTIVES: This study aims to assess t ... Full text Link to item Cite

Influence of ejection fraction on outcomes with sacubitril/valsartan in patients with worsening heart failure with EF>40%: The PARAGLIDE-HF Trial.

Conference Am Heart J · November 2025 BACKGROUND: In the PARAGLIDE-HF trial, treatment with sacubitril/valsartan (Sac/Val) was associated with greater reduction in NT-proBNP than valsartan (Val) alone in patients stabilized after an episode of worsening heart failure (HF) with left ventricular ... Full text Link to item Cite

Structural abnormalities and effects of sacubitril/valsartan in patients with mildly reduced or preserved ejection fraction and worsening heart failure: The PARAGLIDE-HF trial.

Conference Am Heart J · November 2025 BACKGROUND: PARAGLIDE-HF showed significantly greater reduction in NT-proBNP in patients with LVEF>40% and worsening HF with sacubitril/valsartan (sac/val) vs valsartan (val). The impact of structural abnormalities on the effects of sac/val in this context ... Full text Link to item Cite
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Recent Grants


Urinary Stone Research_USDRN-SDRC Grant_Continuation

ResearchBiostatistician · Awarded by Washington University in St. Louis · 2025 - 2026

Urinary Stone Research_USDRN-SDRC Grant_Continuation

ResearchBiostatistician · Awarded by University of Texas Southwestern Medical Center · 2025 - 2026

RADx-UP CDCC

ResearchSenior Statistician · Awarded by National Institutes of Health · 2020 - 2025

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