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Ester Kim Nilles

Biostatistician, Senior
Duke Clinical Research Institute

Current Duke Appointments & Affiliations


Recent Scholarly Works


Evaluating fitness-for-use of electronic health records in ascertaining baseline characteristics and clinical outcomes in clinical trials: insights from the VESALIUS EHR demonstration project.

Journal article Trials · April 25, 2026 INTRODUCTION: A tremendous amount of clinical data is collected and stored in electronic health records (EHRs). Whether this data can be harnessed at scale to facilitate clinical trial conduct remains to be seen. METHODS: The Effect of Evolocumab in Patien ... Full text Link to item Cite

Neonatal outcomes of pregnancy in women with congenital heart disease.

Journal article Am Heart J · January 2026 BACKGROUND: Infants born to women with congenital heart disease (CHD) are at increased risk for adverse outcomes compared with the general population. There are few large, contemporary studies examining the relationship between CHD severity, maternal risk ... Full text Link to item Cite

Abstract 4369193: Burden of Heart Failure in 4,573 Children and Adults with Fontan Physiology: Epidemiology and Outcomes from a Decade-Long Seven-State US-Based Surveillance Network

Conference Circulation · November 4, 2025 Introduction: The prevalence of heart failure (HF) among U.S. patients (pts) with Fontan physiology is poorly defined, with estimates generally derived from single centers. We leverage ... Full text Cite
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Recent Grants


The North Carolina Congenital Heart Disease Surveillance Network

Public ServiceStatistician · Awarded by Centers for Disease Control and Prevention · 2024 - 2029

Partial Heart Transplant Registry.

ResearchStatistician · Awarded by The Brett Boyer Foundation · 2025 - 2027

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

ResearchSenior Statistician · Awarded by Massachusetts General Hospital · 2019 - 2026

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