Evert Njomen

The Njomen Lab leverages stereochemically defined small molecules alongside advanced chemical proteomic methods to discover and characterize ligands for disease-relevant and challenging-to-drug proteins. Specifically, we aim to identify ligands that bind to and modulate specific proteoforms, including protein complexes, and elucidate their effects on protein functions and biological pathways. Our objective is to enhance our understanding of the roles these proteins play in human biology and diseases, ultimately facilitating the development of therapeutic strategies for critical human conditions. Our research adopts a multidisciplinary approach that integrates chemistry, chemoproteomics, molecular biology, enzymology, and assay development across various disease areas, including cancers and inflammatory disorders.