Skip to main content

John Ji

Adjunct Associate Professor in Global Health Research Center at Duke Kunshan University
DKU Faculty
404 Chapel Drive, Flowers Bldg Suite 214, Durham, NC 27708
404 Chapel Drive, Flowers Bldg Suite 214, Durham, NC 27708

Selected Publications


Risk factors associated with heatwave mortality in Chinese adults over 65 years.

Journal Article Nature medicine · May 2024 Aging populations are susceptible to heat-related mortality because of physiological factors and comorbidities. However, the understanding of individual vulnerabilities in the aging population is incomplete. In the Chinese Longitudinal Healthy Longevity Su ... Full text Cite

Projection of Mortality Burden Attributable to Nonoptimum Temperature with High Spatial Resolution in China.

Journal Article Environmental science & technology · April 2024 The updated climate models provide projections at a fine scale, allowing us to estimate health risks due to future warming after accounting for spatial heterogeneity. Here, we utilized an ensemble of high-resolution (25 km) climate simulations and nationwi ... Full text Cite

Real-World Evidence of Multiple Air Pollutants and Mortality: A Prospective Cohort Study in an Oldest-Old Population.

Journal Article Environment & health (Washington, D.C.) · January 2024 We aimed to report real-world longitudinal ambient air pollutants levels compared to WHO Air Quality Guidelines (AQG) and analyze multiple air pollutants' joint effect on longevity, and the modification and confounding from the climate and urbanization wit ... Full text Cite

Trade-offs between cold protection and air pollution-induced mortality of China's heating policy.

Journal Article PNAS nexus · December 2023 The winter heating policy in northern China was designed to safeguard households from the harsh subfreezing temperatures. However, it has inadvertently resulted in seasonal spikes in air pollution levels because of the reliance on coal as an energy source. ... Full text Cite

Exposure to Multiple Air Pollutants and the Risk of Fractures: A Large Prospective Population-Based Study.

Journal Article Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · November 2023 Atmospheric chemistry studies suggest air pollution impedes ultraviolet B photons and thus reduces cutaneous vitamin D3 synthesis. Biological evidence shows that inhaled pollutants disrupt circulating 25-hydroxyvitamin D (25[OH]D) metabolism and ... Full text Cite

China's public health initiatives for climate change adaptation.

Journal Article The Lancet regional health. Western Pacific · November 2023 China's health gains over the past decades face potential reversals if climate change adaptation is not prioritized. China's temperature rise surpasses the global average due to urban heat islands and ecological changes, and demands urgent actions to safeg ... Full text Cite

Projecting future labor losses due to heat stress in China under climate change scenarios.

Journal Article Science bulletin · November 2023 Climate change is expected to increase occupational heat stress, which will lead to diminished work performance and labor losses worldwide. However, sub-regional analyses remain insufficient, especially for countries with a heterogeneous spatial distributi ... Full text Cite

The burden of disease attributable to indoor air pollutants in China from 2000 to 2017.

Journal Article The Lancet. Planetary health · November 2023 BackgroundHigh-level exposure to indoor air pollutants (IAPs) and their corresponding adverse health effects have become a public concern in China in the past 10 years. However, neither national nor provincial level burden of disease attributable ... Full text Cite

Association of greenness surrounding school with aggression among adolescents: A multi-site study in China.

Journal Article Environmental research · October 2023 Association of greenness surrounding school with aggression among adolescents was not well understood. This study aimed to investigate the associations of greenness surrounding school with adolescents' total and sub-types of aggression and explore potentia ... Full text Cite

Automated simulation for household road traffic noise exposure: Application and field evaluation in a high-density city

Journal Article Computers, Environment and Urban Systems · September 1, 2023 Road traffic noise is a major nuisance and a risk factor of poor health for urban dwellers. A household's exposure to road traffic noise, especially in a high-density city, can be easily modified by the surrounding built environment, i.e., roads, traffic, ... Full text Cite

Performance and effectiveness of hepatocellular carcinoma screening in individuals with HBsAg seropositivity in China: a multicenter prospective study.

Journal Article Nature cancer · September 2023 Current guidelines recommend hepatocellular carcinoma (HCC) surveillance for at-risk individuals, including individuals with hepatitis B virus infection. However, the performance and survival benefits of annual screening have not been evaluated through mul ... Full text Cite

Exploration of the preterm birth risk-related heat event thresholds for pregnant women: a population-based cohort study in China.

Journal Article The Lancet regional health. Western Pacific · August 2023 BackgroundHeat events increase the risk of preterm birth (PTB), and identifying the risk-related event thresholds contributes to developing early warning system for pregnant women and guiding their public health response. However, the event thresh ... Full text Cite

Mortality Burden of Cardiovascular Disease Attributable to Ozone in China: 2019 vs 2050.

Journal Article Environmental science & technology · August 2023 Due to a combination of lifestyle risk factors, the burden of cardiovascular disease (CVD) has been increasing in China, affecting an estimated 330 million people. Environmental risk factors can exacerbate these risks or independently contribute to CVD. Oz ... Full text Cite

Projections of excess deaths related to cold spells under climate and population change scenarios: A nationwide time series modeling study.

Journal Article Environment international · August 2023 BackgroundFuture climate change is likely to alter cold spell-related disease burden. Few projection studies have considered the potential impact of the aging population with changing population size on cold spell-related disease burdens.Metho ... Full text Cite

Racial/ethnic disparities in the cause of death among patients with prostate cancer in the United States from 1995 to 2019: a population-based retrospective cohort study.

Journal Article EClinicalMedicine · August 2023 BackgroundRacial/ethnic disparities in prostate cancer are reported in the United States (US). However, long-term trends and contributors of racial/ethnic disparities in all-cause and cause-specific death among patients with prostate cancer remain ... Full text Cite

Building resilience in heatwaves.

Journal Article Nature medicine · July 2023 Full text Cite

Environmental greenspace, subjective well-being, and all-cause mortality in elderly Chinese: Association and mediation study in a prospective cohort.

Journal Article Environmental research · June 2023 BackgroundSubjective well-being (SWB) measures mental health and happiness. Greenspace can have a positive impact on mental health, and higher SWB is associated with lower all-cause mortality. We conducted a mediation analysis on greenspace and al ... Full text Cite

Risk factors associated with heatwave mortality in Chinese adults over 65 years.

Journal Article Nature medicine · May 2024 Aging populations are susceptible to heat-related mortality because of physiological factors and comorbidities. However, the understanding of individual vulnerabilities in the aging population is incomplete. In the Chinese Longitudinal Healthy Longevity Su ... Full text Cite

Projection of Mortality Burden Attributable to Nonoptimum Temperature with High Spatial Resolution in China.

Journal Article Environmental science & technology · April 2024 The updated climate models provide projections at a fine scale, allowing us to estimate health risks due to future warming after accounting for spatial heterogeneity. Here, we utilized an ensemble of high-resolution (25 km) climate simulations and nationwi ... Full text Cite

Real-World Evidence of Multiple Air Pollutants and Mortality: A Prospective Cohort Study in an Oldest-Old Population.

Journal Article Environment & health (Washington, D.C.) · January 2024 We aimed to report real-world longitudinal ambient air pollutants levels compared to WHO Air Quality Guidelines (AQG) and analyze multiple air pollutants' joint effect on longevity, and the modification and confounding from the climate and urbanization wit ... Full text Cite

Trade-offs between cold protection and air pollution-induced mortality of China's heating policy.

Journal Article PNAS nexus · December 2023 The winter heating policy in northern China was designed to safeguard households from the harsh subfreezing temperatures. However, it has inadvertently resulted in seasonal spikes in air pollution levels because of the reliance on coal as an energy source. ... Full text Cite

Exposure to Multiple Air Pollutants and the Risk of Fractures: A Large Prospective Population-Based Study.

Journal Article Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · November 2023 Atmospheric chemistry studies suggest air pollution impedes ultraviolet B photons and thus reduces cutaneous vitamin D3 synthesis. Biological evidence shows that inhaled pollutants disrupt circulating 25-hydroxyvitamin D (25[OH]D) metabolism and ... Full text Cite

China's public health initiatives for climate change adaptation.

Journal Article The Lancet regional health. Western Pacific · November 2023 China's health gains over the past decades face potential reversals if climate change adaptation is not prioritized. China's temperature rise surpasses the global average due to urban heat islands and ecological changes, and demands urgent actions to safeg ... Full text Cite

Projecting future labor losses due to heat stress in China under climate change scenarios.

Journal Article Science bulletin · November 2023 Climate change is expected to increase occupational heat stress, which will lead to diminished work performance and labor losses worldwide. However, sub-regional analyses remain insufficient, especially for countries with a heterogeneous spatial distributi ... Full text Cite

The burden of disease attributable to indoor air pollutants in China from 2000 to 2017.

Journal Article The Lancet. Planetary health · November 2023 BackgroundHigh-level exposure to indoor air pollutants (IAPs) and their corresponding adverse health effects have become a public concern in China in the past 10 years. However, neither national nor provincial level burden of disease attributable ... Full text Cite

Association of greenness surrounding school with aggression among adolescents: A multi-site study in China.

Journal Article Environmental research · October 2023 Association of greenness surrounding school with aggression among adolescents was not well understood. This study aimed to investigate the associations of greenness surrounding school with adolescents' total and sub-types of aggression and explore potentia ... Full text Cite

Automated simulation for household road traffic noise exposure: Application and field evaluation in a high-density city

Journal Article Computers, Environment and Urban Systems · September 1, 2023 Road traffic noise is a major nuisance and a risk factor of poor health for urban dwellers. A household's exposure to road traffic noise, especially in a high-density city, can be easily modified by the surrounding built environment, i.e., roads, traffic, ... Full text Cite

Performance and effectiveness of hepatocellular carcinoma screening in individuals with HBsAg seropositivity in China: a multicenter prospective study.

Journal Article Nature cancer · September 2023 Current guidelines recommend hepatocellular carcinoma (HCC) surveillance for at-risk individuals, including individuals with hepatitis B virus infection. However, the performance and survival benefits of annual screening have not been evaluated through mul ... Full text Cite

Exploration of the preterm birth risk-related heat event thresholds for pregnant women: a population-based cohort study in China.

Journal Article The Lancet regional health. Western Pacific · August 2023 BackgroundHeat events increase the risk of preterm birth (PTB), and identifying the risk-related event thresholds contributes to developing early warning system for pregnant women and guiding their public health response. However, the event thresh ... Full text Cite

Mortality Burden of Cardiovascular Disease Attributable to Ozone in China: 2019 vs 2050.

Journal Article Environmental science & technology · August 2023 Due to a combination of lifestyle risk factors, the burden of cardiovascular disease (CVD) has been increasing in China, affecting an estimated 330 million people. Environmental risk factors can exacerbate these risks or independently contribute to CVD. Oz ... Full text Cite

Projections of excess deaths related to cold spells under climate and population change scenarios: A nationwide time series modeling study.

Journal Article Environment international · August 2023 BackgroundFuture climate change is likely to alter cold spell-related disease burden. Few projection studies have considered the potential impact of the aging population with changing population size on cold spell-related disease burdens.Metho ... Full text Cite

Racial/ethnic disparities in the cause of death among patients with prostate cancer in the United States from 1995 to 2019: a population-based retrospective cohort study.

Journal Article EClinicalMedicine · August 2023 BackgroundRacial/ethnic disparities in prostate cancer are reported in the United States (US). However, long-term trends and contributors of racial/ethnic disparities in all-cause and cause-specific death among patients with prostate cancer remain ... Full text Cite

Building resilience in heatwaves.

Journal Article Nature medicine · July 2023 Full text Cite

Environmental greenspace, subjective well-being, and all-cause mortality in elderly Chinese: Association and mediation study in a prospective cohort.

Journal Article Environmental research · June 2023 BackgroundSubjective well-being (SWB) measures mental health and happiness. Greenspace can have a positive impact on mental health, and higher SWB is associated with lower all-cause mortality. We conducted a mediation analysis on greenspace and al ... Full text Cite

Disparities in stage at diagnosis among breast cancer molecular subtypes in China.

Journal Article Cancer medicine · May 2023 BackgroundDisease stage at diagnosis and molecular subtypes are the main determinants of breast cancer treatment strategies and prognosis. We aimed at examining the disparities and factors associated with the stage at diagnosis among the molecular ... Full text Cite

Sugary beverages and genetic risk in relation to brain structure and incident dementia: a prospective cohort study.

Journal Article The American journal of clinical nutrition · April 2023 BackgroundThe relation of intake of sugary beverages and genetic predisposition to the long-term risk of dementia and brain structure remains unclear.ObjectivesThis study aimed to assess the associations of sugar-sweetened beverages (SSBs ... Full text Cite

Association between Organophosphate Ester Exposure and Insulin Resistance with Glycometabolic Disorders among Older Chinese Adults 60-69 Years of Age: Evidence from the China BAPE Study.

Journal Article Environmental health perspectives · April 2023 BackgroundOrganophosphate esters (OPEs) are common endocrine-disrupting chemicals, and OPE exposure may be associated with type 2 diabetes (T2D). However, greater knowledge regarding the biomolecular intermediators underlying the impact of OPEs on ... Full text Cite

Air Purifier Intervention to Remove Indoor PM2.5 in Urban China: A Cost-Effectiveness and Health Inequality Impact Study.

Journal Article Environmental science & technology · March 2023 Using air purifiers is an intervention to reduce exposure to fine particulate matter (PM2.5) for health benefits. We performed a comprehensive simulation in urban China to estimate the cost-effectiveness of long-term use of air purifiers to remo ... Full text Cite

Immigration and Blood Lead Levels Among Asian Populations in the United States: NHANES 2011-2018.

Journal Article Journal of occupational and environmental medicine · March 2023 ObjectiveThe aim of this study was to explore determinants of high BLLs among the Asian population in the United States.MethodsWe used the US nationally representative National Health and Nutrition Examination Survey (NHANES), 2011-2018. ... Full text Cite

Same stimuli, different responses: a pilot study assessing air pollution visibility impacts on emotional well-being in a controlled environment

Journal Article Frontiers of Environmental Science and Engineering · February 1, 2023 A growing number of studies have shown that impaired visibility caused by particulate matter pollution influences emotional wellbeing. However, evidence is still scant on how this effect varies across individuals and over repetitive visual exposure in a co ... Full text Cite

Long-term fine particular exposure and incidence of frailty in older adults: findings from the Chinese Longitudinal Healthy Longevity Survey.

Journal Article Age and ageing · February 2023 BackgroundThe association between fine particular matter (PM2.5) and frailty is less studied, and the national burden of PM2.5-related frailty in China is unknown.ObjectiveTo explore the association between PM2.5 exposure and incident fra ... Full text Cite

Serum per- and polyfluoroalkyl substances and abnormal lipid metabolism: A nationally representative cross-sectional study.

Journal Article Environment international · February 2023 BackgroundThe associations of legacy per- and polyfluoroalkyl substances (PFAS) with lipid metabolism are controversial, and there is little information about the impact of emerging PFAS (6:2 Cl-PFESA) on lipid metabolism in China.Objectives Full text Cite

Patterns and trends in the cause of death for patients with endometrial cancer.

Journal Article JNCI cancer spectrum · January 2023 BackgroundRacial disparities in endometrial cancer have been reported in the United States, but trends and the underlying causes are not well understood. We aimed to examine the trends and contributing factors in racial disparities for causes of d ... Full text Cite

The impact of fossil fuel combustion on children's health and the associated losses of human capital

Journal Article Global Transitions · January 1, 2023 To more fully assess the far-reaching effects of fossil fuel combustion on humanity, it is necessary to gain an in-depth understanding of the full impact of fossil fuels on human health and lifetime potential. However, current knowledge of the long-term co ... Full text Cite

Biophilic classroom environments on stress and cognitive performance: A randomized crossover study in virtual reality (VR).

Journal Article PloS one · January 2023 The emerging Metaverse will likely increase time expenditure in indoor virtual environments, which could impact human health and well-being. The biophilia hypothesis suggests that humans have an innate tendency to seek connections with the natural world an ... Full text Cite

The burden of heatwave-related preterm births and associated human capital losses in China.

Journal Article Nature communications · December 2022 Frequent heatwaves under global warming can increase the risk of preterm birth (PTB), which in turn will affect physical health and human potential over the life course. However, what remains unknown is the extent to which anthropogenic climate change has ... Full text Cite

China's relocation policy for poverty reduction may save thousands of lives attributable to indoor PM2.5

Journal Article Building and Environment · December 1, 2022 To complete the last stretch of complete poverty eradication by 2020, Chinese policymakers relocated about 10 million rural people from poverty-stricken regions closer to urban areas, between 2016 and 2020. Improved indoor air from transiting out of biomas ... Full text Cite

New onset of type 2 diabetes after colorectal cancer diagnosis: Results from three prospective US cohort studies, systematic review, and meta-analysis.

Journal Article EBioMedicine · December 2022 BackgroundLimited data indicate that patients with colorectal cancer (CRC) are at higher risk of developing type 2 diabetes (T2D). We prospectively examined the risk of T2D between individuals with and without CRC in three large cohorts and conduc ... Full text Cite

Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000-2018.

Journal Article BMC medicine · December 2022 BackgroundHuman immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending t ... Full text Cite

Declines in Blood Lead Levels Among General Population - China, 2000-2018.

Journal Article China CDC weekly · December 2022 What is already known about this topic?Environmental and occupational lead exposure has generally declined in the past two decades. However, there is no large-scale monitoring of blood lead levels (BLLs) in the Chinese general population.What ... Full text Cite

COPD deaths attributable to ozone in 2019 and future projections using the WHO AQG 2021 in urban China.

Journal Article Eco-Environment & Health (Online) · December 2022 Chronic obstructive pulmonary disease (COPD) is an epidemic in China. Ozone is a possible risk factor of COPD, with ozone concentrations increasing in China, despite air pollution mitigation measures that reduced particulate matter. The WHO Air Quality Gui ... Full text Cite

Assessing the effects of ultraviolet radiation, residential greenness and air pollution on vitamin D levels: A longitudinal cohort study in China.

Journal Article Environment international · November 2022 Vitamin D metabolism is essential in aging and can be affected by multiple environmental factors. However, most studies conducted single exposure analyses. We aim to assess the individual and combined effects of ultraviolet (UV) radiation, residential gree ... Full text Cite

Deaths Attributable to Indoor PM2.5 in Urban China When Outdoor Air Meets 2021 WHO Air Quality Guidelines.

Journal Article Environmental science & technology · November 2022 The World Health Organization reduced the recommended level of annual mean PM2.5 concentrations to 5 μg/m3 in 2021. Previously, the guideline was geared toward ambient air pollution, and now it explicitly applies to indoor air polluti ... Full text Cite

Air pollution and cardiovascular disease onset: hours, days, or years?

Journal Article The Lancet. Public health · November 2022 Full text Cite

World Health Forum 2022 at Tsinghua University.

Journal Article Lancet (London, England) · November 2022 Full text Cite

Healthy cities initiative in China: Progress, challenges, and the way forward.

Journal Article The Lancet regional health. Western Pacific · October 2022 China implemented the first phase of its National Healthy Cities pilot program from 2016-20. Along with related urban health governmental initiatives, the program has helped put health on the agenda of local governments while raising public awareness. Heal ... Full text Cite

Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000-18: a geospatial modelling study.

Journal Article The Lancet. Global health · October 2022 BackgroundMore than 3 billion people do not have access to clean energy and primarily use solid fuels to cook. Use of solid fuels generates household air pollution, which was associated with more than 2 million deaths in 2019. Although local patte ... Full text Cite

Association of Long-Term Body Weight Variability With Dementia: A Prospective Study.

Journal Article The journals of gerontology. Series A, Biological sciences and medical sciences · October 2022 BackgroundBody weight variability (BWV) refers to intraindividual weight loss and gain over a period. The association of long-term BWV with dementia remains unclear and whether this association is beyond body weight change is undetermined.Meth ... Full text Cite

NO2 and PM2.5 air pollution co-exposure and temperature effect modification on pre-mature mortality in advanced age: a longitudinal cohort study in China.

Journal Article Environmental health : a global access science source · October 2022 BackgroundThere is a discourse on whether air pollution mixture or air pollutant components are causally linked to increased mortality. In particular, there is uncertainty on whether the association of NO2 with mortality is independent ... Full text Cite

Urinary Creatinine Concentrations and Its Explanatory Variables in General Chinese Population: Implications for Creatinine Limits and Creatinine Adjustment.

Journal Article Biomedical and environmental sciences : BES · October 2022 ObjectiveThe study aimed to analyze the applicability of the World Health Organization's exclusionary guidelines for Urinary creatinine (Ucr) in the general Chinese population, and to identify Ucr related factors.MethodsWe conduct a cross ... Full text Cite

Greenspace and mortality in the U.K. Biobank: Longitudinal cohort analysis of socio-economic, environmental, and biomarker pathways.

Journal Article SSM - population health · September 2022 Exposure to natural greenspace benefits health through direct and indirect pathways: increasing physical activity, improving mental health, relieving social isolation, reducing exposure to extreme temperature, noise, and air pollution. Understanding the et ... Full text Cite

The prevalence of onchocerciasis in Africa and Yemen, 2000-2018: a geospatial analysis.

Journal Article BMC medicine · September 2022 BackgroundOnchocerciasis is a disease caused by infection with Onchocerca volvulus, which is transmitted to humans via the bite of several species of black fly, and is responsible for permanent blindness or vision loss, as well as severe skin dise ... Full text Cite

Effect of FOXO3 and Air Pollution on Cognitive Function: A Longitudinal Cohort Study of Older Adults in China From 2000 to 2014.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 Forkhead Box O 3 (FOXO3) genotype is strongly associated with human longevity and may be protective against neurodegeneration. Air pollution is a risk factor for cognitive decline and dementia. We aimed to study the individual and combined effects of FOXO3 ... Full text Link to item Cite

Comparing Effects of FOXO3 and Residing in Urban Areas on Longevity: A Gene-Environment Interaction Study.

Journal Article The journals of gerontology. Series A, Biological sciences and medical sciences · August 2022 Forkhead box O3 (FOXO3) is a candidate longevity gene. Urban residents are also positively associated with longer life expectancy. We conducted a gene-environment interaction to assess the synergistic effect of FOXO3 and urban/rural environments on mortali ... Full text Cite

Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-Year Prospective Longitudinal Cohort Study.

Journal Article The journals of gerontology. Series A, Biological sciences and medical sciences · August 2022 SIRT1 and FOXO3 are both associated with longevity. Molecular biology research in many organisms (yeast, nematode worm Caenorhabditis elegans, and mice mammalian models) shows SIRT1 acts on the FOXO family of forkhead transcription factors to respond to ox ... Full text Cite

Cardiovascular effects of traffic-related air pollution: A multi-omics analysis from a randomized, crossover trial.

Journal Article Journal of hazardous materials · August 2022 A system-wide cardiovascular response to traffic-related air pollution (TRAP) has been rarely described. To systemically understand the mechanisms underlying cardiovascular effects of TRAP, we conducted a randomized, crossover trial in 56 young adults, who ... Full text Cite

Plant-based dietary patterns and cognitive function: A prospective cohort analysis of elderly individuals in China (2008-2018).

Journal Article Brain and behavior · August 2022 IntroductionPlant-based diets confer health benefits, especially on the prevention of noncommunicable diseases. The relationship between plant-based dietary patterns on cognitive function as a neurological outcome needs more evidence. We aimed to ... Full text Cite

Non-optimum temperature increases risk and burden of acute myocardial infarction onset: A nationwide case-crossover study at hourly level in 324 Chinese cities.

Journal Article EClinicalMedicine · August 2022 BackgroundThe associations of ambient temperature with acute myocardial infarction (AMI) have seldom been examined based on the time of symptom onset.MethodsWe conducted a time-stratified case-crossover study among 1,046,773 eligible AMI ... Full text Cite

Heatwave sears China: Need for actionable climate change adaptation to protect public health.

Journal Article The Lancet regional health. Western Pacific · August 2022 Full text Cite

Restrictions on indoor and outdoor NO2 emissions to reduce disease burden for pediatric asthma in China: A modeling study.

Journal Article The Lancet regional health. Western Pacific · July 2022 BackgroundEpidemiological studies have reported the associations between nitrogen dioxide (NO2) and pediatric asthma incidence, but unable to ascertain indoor NO2 sources. We estimated the pediatric asthma incidence and corre ... Full text Cite

Using an Integrated Framework to Investigate the Facilitators and Barriers of Health Information Technology Implementation in Noncommunicable Disease Management: Systematic Review.

Journal Article Journal of medical Internet research · July 2022 BackgroundNoncommunicable disease (NCD) management is critical for reducing attributable health burdens. Although health information technology (HIT) is a crucial strategy to improve chronic disease management, many health care systems have failed ... Full text Cite

Effects of extreme temperature on the risk of preterm birth in China: A population-based multi-center cohort study.

Journal Article The Lancet regional health. Western Pacific · July 2022 BackgroundExtreme temperatures are associated with the risk of preterm birth (PTB), but evidence on the effects of different clinical subtypes and across different regions is limited. We aimed to evaluate the effects of maternal exposure to extrem ... Full text Cite

The WHO Air Quality Guidelines 2021 promote great challenge for indoor air.

Journal Article The Science of the total environment · June 2022 The WHO AQGs 2021 incorporates more stringent guidelines for air pollution, which now include both ambient and indoor air quality. We discuss the challenges to meeting the AQGs for indoor air. We suggest a cocktail-like treatment solution that combines eff ... Full text Cite

Association between sleep duration and hypertension in southwest China: a population-based cross-sectional study.

Journal Article BMJ open · June 2022 ObjectiveHypertension is a major risk factor and cause of many non-communicable diseases in China. While there have been studies on various diet and lifestyle risk factors, we do not know whether sleep duration has an association to blood pressure ... Full text Cite

Long-term exposure to ozone and cardiovascular mortality in China: a nationwide cohort study.

Journal Article The Lancet. Planetary health · June 2022 BackgroundThe evidence for a causal relationship between long-term ozone exposure and cardiovascular mortality is inconclusive, and most published data are from high-income countries. We aimed to investigate the association between long-term expos ... Full text Cite

Hourly Air Pollutants and Acute Coronary Syndrome Onset in 1.29 Million Patients.

Journal Article Circulation · June 2022 BackgroundShort-term exposure to ambient air pollution has been linked with daily hospitalization and mortality from acute coronary syndrome (ACS); however, the associations of subdaily (hourly) levels of criteria air pollutants with the onset of ... Full text Cite

Solid fuel use, socioeconomic indicators and risk of cardiovascular diseases and all-cause mortality: a prospective cohort study in a rural area of Sichuan, China.

Journal Article International journal of epidemiology · May 2022 BackgroundEstimates indicate that household air pollution caused by solid fuel burning accounted for about 1.03 million premature mortalities in China in 2016. In the country's rural areas, more than half the population still relies on biomass fue ... Full text Cite

Air pollution, residential greenness, and metabolic dysfunction biomarkers: analyses in the Chinese Longitudinal Healthy Longevity Survey.

Journal Article BMC public health · May 2022 BackgroundWe hypothesize higher air pollution and fewer greenness exposures jointly contribute to metabolic syndrome (MetS), as mechanisms on cardiometabolic mortality.MethodsWe studied the samples in the Chinese Longitudinal Healthy Long ... Full text Cite

The obesity paradox is mostly driven by decreased noncardiovascular disease mortality in the oldest old in China: a 20-year prospective cohort study.

Journal Article Nat Aging · May 2022 National and international recommendations of healthy body mass index (BMI) are primarily based on evidence in young and middle-aged populations, with an insufficient representation of the oldest old (aged ≥80 years). Here, we report associations between B ... Full text Link to item Cite

Effect of exposures to mixtures of lead and various metals on hypertension, pre-hypertension, and blood pressure: A cross-sectional study from the China National Human Biomonitoring.

Journal Article Environmental pollution (Barking, Essex : 1987) · April 2022 We aimed to explore the effects of mixtures of lead and various metals on blood pressure (BP) and the odds of pre-hypertension (systolic blood pressure (SBP) 120-139 mmHg, and/or diastolic blood pressure (DBP) 80-89 mmHg) and hypertension (SBP/DBP ≥140/90  ... Full text Cite

Association between residential greenspace structures and frailty in a cohort of older Chinese adults.

Journal Article Communications medicine · April 2022 BackgroundFrailty is a late-life clinical syndrome resulting from the accumulation of aging-induced decline. Greenspaces measured with normalized difference vegetation index (NDVI) are protective of frailty. However, NDVI is not as informative as ... Full text Cite

Association between PM2.5 and daily pharmacy visit tendency in China: A time series analysis using mobile phone cellular signaling data

Journal Article Journal of Cleaner Production · March 15, 2022 While much is known about the effects of PM2.5 pollution on severe health outcomes, less is known about the heterogeneous impacts of air pollution on less severe health effects experienced by large numbers of people, such as those resulting in pharmacy vis ... Full text Cite

Composition of fine particulate matter and risk of preterm birth: A nationwide birth cohort study in 336 Chinese cities.

Journal Article Journal of hazardous materials · March 2022 BackgroundPotential hazards of fine particulate matter (PM2.5) constituents on preterm birth (PTB) have rarely been explored in China.ObjectiveTo quantify the associations of PM2.5 constituents with PTB.Methods Full text Cite

Interaction between plant-based dietary pattern and air pollution on cognitive function: a prospective cohort analysis of Chinese older adults.

Journal Article Lancet Reg Health West Pac · March 2022 BACKGROUND: Air pollution is a risk factor for poor cognitive function, while a plant-based dietary pattern is associated with better cognitive function. We aimed to explore their interaction with cognitive function among older adults. METHODS: We used a p ... Full text Link to item Cite

Plant-based dietary patterns in relation to mortality among older adults in China.

Journal Article Nature aging · March 2022 A plant-based dietary pattern has been recommended for its potential health and environmental benefits, but its relation to mortality warrants further exploration1. We examined this association among 13,154 adults aged 65 years and older (57.4% ... Full text Cite

Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study.

Journal Article BMJ (Clinical research ed.) · March 2022 ObjectivesTo use data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) to estimate mortality and disability trends for the population aged ≥70 and evaluate patterns in causes of death, disability, and risk facto ... Full text Cite

Dynamic molecular choreography induced by traffic exposure: A randomized, crossover trial using multi-omics profiling.

Journal Article Journal of hazardous materials · February 2022 The biological mechanism of adverse health outcomes related to exposure to traffic-related air pollution (TRAP) needs elucidation. We conducted a randomized, crossover trial among healthy young students in Shanghai, China. Participants wore earplugs and we ... Full text Cite

Association between Cold Spells and Mortality Risk and Burden: A Nationwide Study in China.

Journal Article Environmental health perspectives · February 2022 BackgroundFew multicity studies have evaluated the association between cold spells and mortality risk and burden.ObjectivesWe aimed to estimate the association between cold spells and cause-specific mortality and to evaluate the mortality ... Full text Cite

Impact of ozone exposure on heart rate variability and stress hormones: A randomized-crossover study.

Journal Article Journal of hazardous materials · January 2022 The biological mechanisms underlying the associations between atmospheric ozone exposure and adverse cardiometabolic outcomes are yet to be identified. Imbalanced autonomic nervous system (ANS) as well as activations of the sympatho-adrenomedullary (SAM) a ... Full text Cite

Prevention and control of coronavirus disease 2019 (COVID-19) in public places.

Journal Article Environmental pollution (Barking, Essex : 1987) · January 2022 Public places favor the transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) due to dense population, large personal mobility, and higher contact opportunities. In order to protect the health of general public in operating public pl ... Full text Cite

Fine particulate matter air pollution and under-5 children mortality in China: A national time-stratified case-crossover study.

Journal Article Environment international · January 2022 BackgroundUnder-5 mortality rate is an important indicator in Millennium Development Goals and Sustainable Development Goals. To date, no nationally representative studies have examined the effects of fine particulate matter (PM2.5) air ... Full text Cite

Is outdoor exercise in air polluted cities a major threat to global health?

Journal Article Ecotoxicology and environmental safety · January 2022 Full text Cite

Chronic kidney disease biomarkers and mortality among older adults: A comparison study of survey samples in China and the United States.

Journal Article PLoS One · 2022 OBJECTIVES: Among older adults in China and the US, we aimed to compare the biomarkers of chronic-kidney-diseases (CKD), factors associated with CKD, and the correlation between CKD and mortality. SETTING: China and the US. STUDY DESIGN: Cross-sectional an ... Full text Link to item Cite

Association of city-level walkability, accessibility to biking and public transportation and socio-economic features with COVID-19 infection in Massachusetts, USA: An ecological study.

Journal Article Geospatial health · January 2022 With people restricted to their residences, neighbourhood characteristics may affect behaviour and risk of coronavirus disease 2019 (COVID-19) infection. We aimed to analyse whether neighbourhoods with higher walkability, public transit, biking services an ... Full text Cite

Association between residential greenspace structures and frailty in a cohort of older Chinese adults.

Journal Article Communications medicine · January 2022 BackgroundFrailty is a late-life clinical syndrome resulting from the accumulation of aging-induced decline. Greenspaces measured with normalized difference vegetation index (NDVI) are protective of frailty. However, NDVI is not as informative as ... Full text Cite

What are the risk factors of hospital length of stay in the novel coronavirus pneumonia (COVID-19) patients? A survival analysis in southwest China.

Journal Article PloS one · January 2022 BackgroundThe global epidemic of novel coronavirus pneumonia (COVID-19) has resulted in substantial healthcare resource consumption. Since patients' hospital length of stay (LoS) is at stake in the process, an investigation of COVID-19 patients' L ... Full text Cite

Effect of heatwaves and greenness on mortality among Chinese older adults.

Journal Article Environ Pollut · December 1, 2021 Heatwaves and greenness have been shown to affect health, but the evidence on their joint effects is limited. We aim to assess the associations of the combined exposure to greenness and heatwaves. We utilized five waves (February 2000-October 2014) of the ... Full text Link to item Cite

The exposome in practice: an exploratory panel study of biomarkers of air pollutant exposure in Chinese people aged 60-69 years (China BAPE Study).

Journal Article Environment international · December 2021 The exposome overhauls conventional environmental health impact research paradigms and provides a novel methodological framework that comprehensively addresses the complex, highly dynamic interplays of exogenous exposures, endogenous exposures, and modifia ... Full text Cite

Disparities in stage at diagnosis for five common cancers in China: a multicentre, hospital-based, observational study.

Journal Article The Lancet. Public health · December 2021 BackgroundStage information is crucial for cancer care and essential to improve polices for cancer control. However, the distribution of stage at diagnosis for common cancers in China is not well known. We aimed to identify the distribution and fa ... Full text Cite

Interaction of greenness and polygenic risk score of Alzheimer's disease on risk of cognitive impairment.

Journal Article Sci Total Environ · November 20, 2021 Studies have shown contact with nature has positive psychological, neurological, and cognitive benefits. Whether the built environment can affect genetic predisposition of Alzheimer's disease (AD) should be explored. We aimed to examine whether greenness a ... Full text Link to item Cite

Human biomonitoring of toxic and essential metals in younger elderly, octogenarians, nonagenarians and centenarians: Analysis of the Healthy Ageing and Biomarkers Cohort Study (HABCS) in China.

Journal Article Environment international · November 2021 BackgroundMetals can be either toxic or essential to health, as they play different role in oxidative stress and metabolic homeostasis during the ageing process. Population-based biomonitoring have documented levels and ranges in concentrations am ... Full text Cite

Is green space exposure beneficial in a developing country?

Journal Article Landscape and Urban Planning · November 1, 2021 Previous studies have confirmed the beneficial effects of green space exposure on depressive disorders, but the majority of them were conducted in developed countries. Given the difference in utilization of green spaces in countries with agriculturally hea ... Full text Cite

Cognitive impairment and all-cause mortality among Chinese adults aged 80 years or older.

Journal Article Brain and behavior · October 2021 ObjectivesThe oldest-old (aged ≥80 years) are the fastest growing population segment and age is related to cognitive impairment. We aimed to estimate the association between cognitive impairment and all-cause mortality, in addition to the relation ... Full text Cite

Megacity, Microscale Livable Space, and Major Depression.

Journal Article JAMA network open · October 2021 Full text Cite

Global, regional, and national mortality among young people aged 10-24 years, 1950-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Journal Article Lancet (London, England) · October 2021 BackgroundDocumentation of patterns and long-term trends in mortality in young people, which reflect huge changes in demographic and social determinants of adolescent health, enables identification of global investment priorities for this age grou ... Full text Cite

Building energy and thermo-hydraulic simulation (BETHS) for district heat system in residential communities: A case of Shenyang, China

Journal Article Energy and Buildings · September 15, 2021 District Heating Systems (DHS) have received renewed attention in relation to theirtheir environmental, economic, and health benefits. Research literature on DHS tends to focus separately, either on the thermo-hydrological modelling or building energy dema ... Full text Cite

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019.

Journal Article Lancet · September 4, 2021 BACKGROUND: Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirt ... Full text Link to item Cite

Residential green space structures and mortality in an elderly prospective longitudinal cohort in China

Journal Article Environmental Research Letters · September 1, 2021 Greenness is beneficial to health and is associated with lower mortality. Many studies used the normalized difference vegetation index (NDVI) to measure greenness. However, NDVI cannot be used to indicate landscape type. To go beyond NDVI, we aim to study ... Full text Cite

Projection of Temperature-Related Excess Mortality by Integrating Population Adaptability Under Changing Climate - China, 2050s and 2080s.

Journal Article China CDC weekly · August 2021 What is already known about this topic?An increasing number of studies have projected temperature-related mortality, but few consider the change of population's adaptability to future temperature and mortality burden from cold and heat effects. Full text Cite

Facilities for Centralized Isolation and Quarantine for the Observation and Treatment of Patients with COVID-19.

Journal Article Engineering (Beijing, China) · July 2021 The coronavirus disease 2019 (COVID-19) pandemic increased the burden on many healthcare systems and in the process, exposed the need for medical resources and physical space. While few studies discussed the efficient utilization of medical resources and p ... Full text Cite

Sleep duration, vegetable consumption and all-cause mortality among older adults in China: a 6-year prospective study.

Journal Article BMC Geriatr · June 21, 2021 BACKGROUND: Sleep duration and vegetable consumption are associated with mortality at old age (termed as sleep-mortality linkage and vegetable-mortality linkage, respectively). Yet, little is known about the interplay of sleep duration and vegetable consum ... Full text Link to item Cite

Effect modification of greenness on temperature-mortality relationship among older adults: A case-crossover study in China.

Journal Article Environmental research · June 2021 BackgroundClimate change exacerbates temperature-related mortality, but effects may vary by geographic characteristics. We hypothesize that higher greenness may mitigate temperature-related mortality, and that the effect may vary in different area ... Full text Cite

Association of APOE ε4 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study.

Journal Article PLoS Med · June 2021 BACKGROUND: Apolipoprotein E (APOE) ε4 is the single most important genetic risk factor for cognitive impairment and Alzheimer disease (AD), while lifestyle factors such as smoking, drinking, diet, and physical activity also have impact on cognition. The g ... Full text Link to item Cite

Interaction of Sirtuin 1 (SIRT1) candidate longevity gene and particulate matter (PM2.5) on all-cause mortality: a longitudinal cohort study in China.

Journal Article Environ Health · March 14, 2021 BACKGROUND: The SIRT1 gene was associated with the lifespan in several organisms through inflammatory and oxidative stress pathways. Long-term air particulate matter (PM) is detrimental to health through the same pathways. METHODS: We used the Chinese Long ... Full text Link to item Cite

Association of low blood arsenic exposure with level of malondialdehyde among Chinese adults aged 65 and older.

Journal Article The Science of the total environment · March 2021 High environmental arsenic exposure can increase chronic oxidative stress in experimental studies and in occupational epidemiology studies. Many regulatory agencies have put forth arsenic exposure limits, it is still unclear that whether low environmental ... Full text Cite

Gene-Environment Interaction of FOXO and Residential Greenness on Mortality Among Older Adults.

Journal Article Rejuvenation Res · February 2021 Featured Publication Residential greenness is an important environmental factor that is strongly associated with mortality. To our knowledge, there was no previous study on the gene-environment interaction analysis between residential greenness and forkhead box O (FOXO) gene, ... Full text Link to item Cite

Gray cityscape caused by particulate matter pollution hampers human stress recovery

Journal Article Journal of Cleaner Production · January 10, 2021 Air pollution has caused degraded visibility and gray cityscape in many developing countries. Though this visual change affects daily life from various aspects, there still lacks evidence on how it influences human psychological and physiological wellbeing ... Full text Cite

Warmer weather unlikely to reduce the COVID-19 transmission: An ecological study in 202 locations in 8 countries.

Journal Article The Science of the total environment · January 2021 PurposeTo examine the association between meteorological factors (temperature, relative humidity, wind speed, and UV radiation) and transmission capacity of COVID-19.MethodsWe collected daily numbers of COVID-19 cases in 202 locations in ... Full text Cite

Mapping routine measles vaccination in low- and middle-income countries.

Journal Article Nature · January 2021 The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income ... Full text Link to item Cite

Apolipoprotein E Induced Cognitive Dysfunction: Mediation Analysis of Lipids and Glucose Biomarkers in an Elderly Cohort Study.

Journal Article Front Aging Neurosci · 2021 INTRODUCTION: Prior evidence suggested Apolipoprotein E (APOE), lipids, and glucose metabolism may act through the same pathways on the pathogenesis of Alzheimer's disease (AD). METHODS: This prospective study used data from the Chinese Longitudinal Health ... Full text Link to item Cite

Residential Greenness Alters Serum 25(OH)D Concentrations: A Longitudinal Cohort of Chinese Older Adults.

Journal Article J Am Med Dir Assoc · December 2020 Featured Publication OBJECTIVES: Vitamin D deficiency is prevalent among older adults. We aimed to study whether residential greenness could alter serum 25(OH)D concentrations as a possible mechanism of residential greenness's positive health effects. DESIGN: A longitudinal co ... Full text Link to item Cite

Modification of vitamin B6 on the associations of blood lead levels and cardiovascular diseases in the US adults.

Journal Article BMJ nutrition, prevention & health · December 2020 BackgroundCardiovascular disease (CVD) is a leading cause of death in the US population. Lead exposure is an important risk factor of CVDs, as is associated with elevated homocysteine level and oxidative stress. We aim to examine whether vitamin B ... Full text Cite

Prevention and control of COVID-19 in nursing homes, orphanages, and prisons.

Journal Article Environmental pollution (Barking, Essex : 1987) · November 2020 As the number of Coronavirus Disease (2019) (COVID-19) cases increase globally, countries are taking more aggressive preventive measures against this pandemic. Transmission routes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) include drop ... Full text Cite

Mask use during COVID-19: A risk adjusted strategy.

Journal Article Environmental pollution (Barking, Essex : 1987) · November 2020 In the context of Coronavirus Disease (2019) (COVID-19) cases globally, there is a lack of consensus across cultures on whether wearing face masks is an effective physical intervention against disease transmission. This study 1) illustrates transmission ro ... Full text Cite

Prevention and control of COVID-19 in public transportation: Experience from China.

Journal Article Environmental pollution (Barking, Essex : 1987) · November 2020 Due to continuous spread of coronavirus disease 2019 (COVID-19) worldwide, long-term effective prevention and control measures should be adopted for public transport facilities, as they are increasing in popularity and serve as the principal modes for trav ... Full text Cite

Aerosol transmission of SARS-CoV-2? Evidence, prevention and control.

Journal Article Environment international · November 2020 As public health teams respond to the pandemic of coronavirus disease 2019 (COVID-19), containment and understanding of the modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission is of utmost importance for policy making. During ... Full text Cite

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 BACKGROUND: Achieving universal health coverage (UHC) involves all people receiving the health services they need, of high quality, without experiencing financial hardship. Making progress towards UHC is a policy priority for both countries and global inst ... Full text Link to item Cite

Five insights from the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 ... Full text Open Access Link to item Cite

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 BACKGROUND: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study ... Full text Link to item Cite

Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 BACKGROUND: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries ... Full text Link to item Cite

Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 BACKGROUND: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. Th ... Full text Link to item Cite

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17.

Journal Article The Lancet. Global health · September 2020 BackgroundUniversal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolutio ... Full text Cite

The global distribution of lymphatic filariasis, 2000-18: a geospatial analysis.

Journal Article The Lancet. Global health · September 2020 BackgroundLymphatic filariasis is a neglected tropical disease that can cause permanent disability through disruption of the lymphatic system. This disease is caused by parasitic filarial worms that are transmitted by mosquitos. Mass drug administ ... Full text Cite

Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17.

Journal Article The Lancet. Global health · August 2020 BackgroundOral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years w ... Full text Cite

Association Between Blood Lead Level and Uncontrolled Hypertension in the US Population (NHANES 1999-2016).

Journal Article Journal of the American Heart Association · July 2020 Featured Publication Background This study aims to explore whether higher blood lead levels (BLL) may be associated with failure to control blood pressure and subsequent uncontrolled hypertension. Methods and Results We used serial cross-sectional waves of the US National Heal ... Full text Cite

Residential Greenness and Frailty Among Older Adults: A Longitudinal Cohort in China.

Journal Article Journal of the American Medical Directors Association · June 2020 ObjectivesFrailty is an accumulation of deficits characterized by reduced resilience to stressors and increased vulnerability to adverse outcomes. There is evolving evidence on the health benefits of residential greenness, but little is known abou ... Full text Cite

Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet (London, England) · June 2020 BackgroundAcross low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea incidence and mortality is attributable t ... Full text Cite

Fine Particulate Matter and Poor Cognitive Function among Chinese Older Adults: Evidence from a Community-Based, 12-Year Prospective Cohort Study.

Journal Article Environ Health Perspect · June 2020 Featured Publication BACKGROUND: Research on the relationship between long-term exposure to particulate matter with aerodynamic diameter ≤2.5μm (PM2.5) and poor cognitive function is lacking in developing countries, especially in highly polluted areas. OBJECTIVES: We evaluated ... Full text Link to item Cite

Department of Error.

Journal Article Lancet (London, England) · June 2020 Full text Cite

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017.

Journal Article Nat Med · May 2020 A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- ... Full text Open Access Link to item Cite

The Paradox Association between Smoking and Blood Pressure among Half Million Chinese People.

Journal Article International journal of environmental research and public health · April 2020 Background: The association between smoking and blood pressure (BP) has been explored extensively, yet the results remain inconclusive. Using real-world evidence of a large Chinese population, we examine the effect of smoking on BP levels. Method ... Full text Cite

Interaction between residential greenness and air pollution mortality: analysis of the Chinese Longitudinal Healthy Longevity Survey.

Journal Article The Lancet. Planetary health · March 2020 Featured Publication BackgroundBoth air pollution and green space have been shown to affect health. We aimed to assess whether greenness protects against air pollution-related mortality.MethodsWe used data from the 2008 wave of the Chinese Longitudinal Health ... Full text Cite

Origins of MERS-CoV, and lessons for 2019-nCoV.

Journal Article The Lancet. Planetary health · March 2020 Full text Cite

The IMO 2020 sulphur cap: a step forward for planetary health?

Journal Article The Lancet. Planetary health · February 2020 Full text Cite

APOE ε4 Modifies Effect of Residential Greenness on Cognitive Function among Older Adults: A Longitudinal Analysis in China.

Journal Article Sci Rep · January 9, 2020 Featured Publication We tested whether the protective effects of residential greenness on cognitive function differ by APOE ε4 status by using the Chinese Longitudinal Healthy Longevity Survey (CLHLS). We calculated Normalized Difference Vegetation Index (NDVI) using 500 m rad ... Full text Link to item Cite

Association of Serum Vitamins with Eczema in US Adults (NHANES 2005-2006).

Journal Article Dermatology (Basel, Switzerland) · January 2020 Full text Cite

Mapping disparities in education across low- and middle-income countries.

Journal Article Nature · January 2020 Featured Publication Educational attainment is an important social determinant of maternal, newborn, and child health1-3. As a tool for promoting gender equity, it has gained increasing traction in popular media, international aid strategies, and global agenda-setting4-6. The ... Full text Open Access Link to item Cite

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study.

Journal Article JAMA Oncol · December 1, 2019 IMPORTANCE: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the ... Full text Link to item Cite

Trends of Blood Cadmium Concentration Among Workers and Non-Workers in the United States (NHANES 2003 to 2012).

Journal Article Journal of occupational and environmental medicine · December 2019 ObjectiveWe aimed to explore the trends of blood cadmium (bCd) concentrations among workers and non-workers in the United States.MethodsWe used serial cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) ... Full text Cite

A Comparison Study of Vitamin D Deficiency among Older Adults in China and the United States.

Journal Article Scientific reports · December 2019 Vitamin D deficiency is a common health concern worldwide. We aim to compare the prevalence of vitamin D deficiency among older adults (65+) in China and the United States (US). We used data from the 2011 wave of Chinese Longitudinal Healthy Longevity Surv ... Full text Cite

Global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2017, and forecasts to 2030, for 195 countries and territories: a systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017.

Journal Article The lancet. HIV · December 2019 BackgroundUnderstanding the patterns of HIV/AIDS epidemics is crucial to tracking and monitoring the progress of prevention and control efforts in countries. We provide a comprehensive assessment of the levels and trends of HIV/AIDS incidence, pre ... Full text Cite

Current situation and progress toward the 2030 health-related Sustainable Development Goals in China: A systematic analysis.

Journal Article PLoS Med · November 2019 BACKGROUND: The Sustainable Development Goals (SDGs), adopted by all United Nations (UN) member states in 2015, established a set of bold and ambitious health-related targets to achieve by 2030. Understanding China's progress toward these targets is critic ... Full text Link to item Cite

Mapping 123 million neonatal, infant and child deaths between 2000 and 2017.

Journal Article Nature · October 2019 Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2-to end preventable child deaths by 2030-we need con ... Full text Open Access Cite

Utilization and expenses of outpatient services among tuberculosis patients in three Chinese counties: an observational comparison study.

Journal Article Infectious diseases of poverty · October 2019 BackgroundThe China-Gates TB project Phase II implemented case-based payment reform in three Chinese counties in 2014, designed specifically for patients diagnosed with Tuberculosis (TB). This study aimed to examine the changes in utilization and ... Full text Cite

Residential greenness, activities of daily living, and instrumental activities of daily living: A longitudinal cohort study of older adults in China.

Journal Article Environmental epidemiology (Philadelphia, Pa.) · October 2019 We aimed to explore whether higher levels of residential greenness were related to lower odds of disabilities in activities of daily living (ADL) and instrumental activities of daily living (IADL).MethodsWe included older adults 65 years of age or ... Full text Cite

Time for health to enter China's climate action framework.

Journal Article The Lancet. Public health · September 2019 Featured Publication Full text Open Access Cite

Factors Influencing Hospitalization Rates and Inpatient Cost of Patients with Tuberculosis in Jiangsu Province, China: An Uncontrolled before and after Study.

Journal Article International journal of environmental research and public health · August 2019 ObjectiveThe China Center for Disease Control and Prevention (CDC) introduced an innovative financing model of tuberculosis (TB) care and control with the aim of standardizing TB treatment and reducing the financial burden associated with patients ... Full text Open Access Cite

Department of Error.

Journal Article Lancet · June 22, 2019 Full text Link to item Cite

Inverted U-shaped relationship between vitamin D and ever-reported eczema in US adults.

Journal Article Allergy · May 2019 Featured Publication BACKGROUND: Eczema is a skin condition which affects up to 10% to 20% of people worldwide. Previous literature finds that low vitamin D levels may be a risk factor for eczema, but the association is not clear. METHODS: We used the cross-sectional data from ... Full text Link to item Cite

Maternofetal outcomes of obstructed labor among women who gave birth at general hospital in Ethiopia.

Journal Article BMC research notes · March 2019 ObjectiveObstructed labor had different maternal outcomes such as uterine rupture, postpartum hemorrhage, puerperal sepsis, Vesico-Vaginal fistula (VVF), recto-vaginal fistula can leads to death. Besides fetal outcomes including birth asphyxia, st ... Full text Cite

Association of environmental exposure to heavy metals and eczema in US population: Analysis of blood cadmium, lead, and mercury.

Journal Article Archives of environmental & occupational health · January 2019 ObjectivesWe aim to explore the association between blood heavy metal concentrations of cadmium, lead, and mercury with ever-report of eczema in the US population.MethodsWe used NHANES cross-sectional data from 2005-2006. Eczema was measu ... Full text Cite

Residential greenness and mortality in oldest-old women and men in China: a longitudinal cohort study.

Journal Article Lancet Planet Health · January 2019 Featured Publication BACKGROUND: Exposure to natural vegetation, or greenness, might affect health through several pathways, including increased physical activity and social engagement, improved mental health, and reductions in exposure to air pollution, extreme temperatures, ... Full text Link to item Cite

Association between residential greenness and cognitive function: analysis of the Chinese Longitudinal Healthy Longevity Survey.

Journal Article BMJ nutrition, prevention & health · January 2019 IntroductionProximity to vegetated green space has been linked to better physical and mental health. However, the relationship between residential greenness and cognitive function and its decline among older adults is not clear in large cohort stu ... Full text Cite

Global, regional, and national burden of motor neuron diseases 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

Journal Article The Lancet. Neurology · December 2018 Featured Publication BackgroundUnderstanding how prevalence, incidence, and mortality of motor neuron diseases change over time and by location is crucial for understanding the causes of these disorders and for health-care planning. Our aim was to produce estimates of ... Full text Cite

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk-outcome ... Full text Open Access Link to item Cite

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 20 ... Full text Open Access Link to item Cite

Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global B ... Full text Open Access Link to item Cite

Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates of population and fertility, alth ... Full text Open Access Link to item Cite

Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no on ... Full text Open Access Link to item Cite

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We c ... Full text Open Access Link to item Cite

Air pollution and China's ageing society.

Journal Article The Lancet. Public health · October 2018 Featured Publication Full text Cite

Changing cancer survival in China during 2003-15: a pooled analysis of 17 population-based cancer registries.

Journal Article The Lancet. Global health · May 2018 BackgroundFrom 2003 to 2005, standardised 5-year cancer survival in China was much lower than in developed countries and varied substantially by geographical area. Monitoring population-level cancer survival is crucial to the understanding of the ... Full text Open Access Cite

Extracellular Vesicles: A Brief Overview and Its Role in Precision Medicine.

Journal Article Methods in molecular biology (Clifton, N.J.) · January 2017 Precision medicine has emerged as an approach to tailor therapies for an individual at the time of diagnosis and/or treatment. This emergence has been fueled by the ability to profile nucleic acids, along with proteins and lipids isolated from biofluids, a ... Full text Cite

Cancer Liquid Biopsy: Is It Ready for Clinic?

Journal Article IEEE pulse · January 2017 The management of cancer relies on a combination of imaging and tissue biopsy for diagnosis, monitoring, and molecular classification-based patient stratification to ensure appropriate treatment. Conventional tissue biopsy harvests tumor samples with invas ... Full text Cite

UHC Presents Universal Challenges.

Journal Article Health systems and reform · January 2016 Full text Cite

Lead exposure and tremor among older men: the VA normative aging study.

Journal Article Environmental health perspectives · May 2015 Featured Publication BackgroundTremor is one of the most common neurological signs, yet its etiology is poorly understood. Case-control studies suggest an association between blood lead and essential tremor, and that this association is modified by polymorphisms in th ... Full text Open Access Cite

Occupational determinants of cumulative lead exposure: analysis of bone lead among men in the VA normative aging study.

Journal Article Journal of occupational and environmental medicine · April 2014 ObjectivesTo examine the relation between occupation and cumulative lead exposure-assessed by measuring bone lead-in a community-dwelling population.MethodWe measured bone lead concentration with K-shell X-Ray Fluorescence in 1320 men in ... Full text Open Access Cite

Association between blood lead and walking speed in the National Health and Nutrition Examination Survey (NHANES 1999-2002).

Journal Article Environmental health perspectives · June 2013 Featured Publication BackgroundWalking speed is a simple and reliable measure of motor function that is negatively associated with adverse health events in older people, including falls, disability, hospital admissions, and mortality. Lead has adverse affects on human ... Full text Open Access Cite